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SARS-CoV-2 spike in complex with the S2M11 neutralizing antibody Fab fragment
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2M11 Fab fragment (heavy chain), ...
Authors:	Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2020-09-14
Release date:	2020-10-07
Last modified:	2021-01-27
Method:	ELECTRON MICROSCOPY (2.6 Å)
Cite:	Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms. Science, 370, 2020

7K45

SARS-CoV-2 spike in complex with the S2E12 neutralizing antibody Fab fragment (local refinement of the RBD and Fab variable domains)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2E12 neutralizing antibody Fab fragment (heavy chain), S2E12 neutralizing antibody Fab fragment (light chain), ...
Authors:	Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2020-09-14
Release date:	2020-10-07
Last modified:	2023-10-18
Method:	ELECTRON MICROSCOPY (3.7 Å)
Cite:	Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms. Science, 370, 2020

7K4N

SARS-CoV-2 spike in complex with the S2E12 neutralizing antibody Fab fragment
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2E12 neutralizing antibody Fab fragment (heavy chain), ...
Authors:	Tortorici, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2020-09-15
Release date:	2020-10-07
Last modified:	2020-12-02
Method:	ELECTRON MICROSCOPY (3.3 Å)
Cite:	Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms. Science, 370, 2020

7K3Q

An ultra-potent human neutralizing antibody locks the SARS-CoV-2 spike in the closed conformation
Descriptor:	1,2-ETHANEDIOL, Fab fragment of S2E12 monoclonal antibody, heavy chain, ...
Authors:	Snell, G, Czudnochowski, N, Ng, C.
Deposit date:	2020-09-12
Release date:	2020-10-07
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (1.38 Å)
Cite:	Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms. Science, 370, 2020

7R7N

SARS-CoV-2 spike in complex with the S2D106 neutralizing antibody Fab fragment (local refinement of the RBD and S2D106)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, S2D106 FAB heavy chain, S2D106 FAB light chain, ...
Authors:	Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-06-25
Release date:	2021-07-21
Last modified:	2021-09-15
Method:	ELECTRON MICROSCOPY (3.95 Å)
Cite:	SARS-CoV-2 RBD antibodies that maximize breadth and resistance to escape. Nature, 597, 2021

7RA8

SARS-CoV-2 S glycoprotein in complex with S2X259 Fab
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Heavy chain Fab S2X259 Fab variable domain, ...
Authors:	Veesler, D, Tortorici, M.A, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-06-30
Release date:	2021-08-04
Last modified:	2021-09-15
Method:	ELECTRON MICROSCOPY (3.1 Å)
Cite:	Broad sarbecovirus neutralization by a human monoclonal antibody. Nature, 597, 2021

7RAL

SARS-CoV-2 S bound to S2X259 Fab (local refinement of the RBD/S2X259 variable domains)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, S2X259 Fab heavy chain, S2X259 Fab light chain, ...
Authors:	Veesler, D, Tortorici, M.A, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-07-01
Release date:	2021-08-04
Last modified:	2021-09-15
Method:	ELECTRON MICROSCOPY
Cite:	Broad sarbecovirus neutralization by a human monoclonal antibody. Nature, 597, 2021

7TAT

SARS-CoV-2 spike in complex with the S2K146 neutralizing antibody Fab fragment (two receptor-binding domains open)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2K146 Fab heavy chain, ...
Authors:	Park, Y.J, Seattle Structural Genomics Center for Infectious Disease (SSGCID), Veesler, D.
Deposit date:	2021-12-21
Release date:	2022-01-12
Last modified:	2022-02-09
Method:	ELECTRON MICROSCOPY (3.2 Å)
Cite:	Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry. Science, 375, 2022

7TAS

SARS-CoV-2 spike in complex with the S2K146 neutralizing antibody Fab fragment (local refinement of the RBD and S2K146)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, S2K146 Fab heavy chain, S2K146 Fab light chain, ...
Authors:	Park, Y.J, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-12-21
Release date:	2022-01-12
Last modified:	2022-02-09
Method:	ELECTRON MICROSCOPY (3.2 Å)
Cite:	Antibody-mediated broad sarbecovirus neutralization through ACE2 molecular mimicry. Science, 375, 2022

6TOU

Rabies virus glycoprotein PH domain in complex with the scFv fragment of broadly neutralizing human antibody RVC20
Descriptor:	CALCIUM ION, CHLORIDE ION, Glycoprotein,Glycoprotein, ...
Authors:	Hellert, J, Rey, F.A.
Deposit date:	2019-12-12
Release date:	2020-02-12
Last modified:	2024-05-01
Method:	X-RAY DIFFRACTION (2.587 Å)
Cite:	Structure of the prefusion-locking broadly neutralizing antibody RVC20 bound to the rabies virus glycoprotein. Nat Commun, 11, 2020

6URM

Crystal structure of vaccine-elicited receptor-binding site targeting antibody LPAF-a.01 in complex with Hemagglutinin H1 A/California/04/2009
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCEROL, ...
Authors:	Zhou, T, Cheung, S.F, Kwong, P.D.
Deposit date:	2019-10-23
Release date:	2020-09-16
Last modified:	2023-10-11
Method:	X-RAY DIFFRACTION (2.65 Å)
Cite:	Identification and Structure of a Multidonor Class of Head-Directed Influenza-Neutralizing Antibodies Reveal the Mechanism for Its Recurrent Elicitation. Cell Rep, 32, 2020

5TDG

Crystal structure of prefusion-stabilized bovine RSV F (DS-Cav1 variant: strain ATue51908)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Fusion glycoprotein F0,Fibritin
Authors:	Chen, L, Zhang, B, Kwong, P.D.
Deposit date:	2016-09-19
Release date:	2017-08-16
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (2.65 Å)
Cite:	Protection of calves by a prefusion-stabilized bovine RSV F vaccine. NPJ Vaccines, 2, 2017

5TDL

Crystal structure of prefusion-stabilized bovine RSV fusion glycoprotein (single-chain DS2-v1 variant: strain 391-2 sc9 DS-Cav1 Q98C Q361C)
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, Bovine prefusion RSV F glycoprotein
Authors:	Chen, L, Zhang, B, Kwong, P.D.
Deposit date:	2016-09-19
Release date:	2017-08-16
Last modified:	2020-07-29
Method:	X-RAY DIFFRACTION (3.5 Å)
Cite:	Protection of calves by a prefusion-stabilized bovine RSV F vaccine. NPJ Vaccines, 2, 2017

7SOF

SARS-CoV-2 S NTD B.1.617.1 kappa variant S2X303 Local Refinement
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, S2X303 Fab heavy chain, S2X303 Fab light chain, ...
Authors:	McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-10-29
Release date:	2021-11-17
Last modified:	2022-01-05
Method:	ELECTRON MICROSCOPY (3.6 Å)
Cite:	Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants. Science, 374, 2021

7SOE

SARS-CoV-2 S B.1.617.1 kappa variant + S2X303 Global Refinement
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2X303 Fab heavy chain, ...
Authors:	McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-10-29
Release date:	2021-11-17
Last modified:	2022-06-08
Method:	ELECTRON MICROSCOPY (2.8 Å)
Cite:	Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants. Science, 374, 2021

7SOC

SARS-CoV-2 S RBD B.1.617.1 kappa variant S309 Local Refinement
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, S309 Fab heavy chain, S309 Fab light chain, ...
Authors:	McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-10-29
Release date:	2021-11-17
Last modified:	2022-01-05
Method:	ELECTRON MICROSCOPY (3.3 Å)
Cite:	Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants. Science, 374, 2021

7SOB

SARS-CoV-2 S B.1.617.1 kappa variant + S309 + S2L20 Global Refinement
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, S2L20 Fab heavy chain, S2L20 Fab light chain, ...
Authors:	McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-10-29
Release date:	2021-11-17
Last modified:	2022-01-05
Method:	ELECTRON MICROSCOPY (2.4 Å)
Cite:	Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants. Science, 374, 2021

7SO9

SARS-CoV-2 S B.1.617.2 delta variant + S2M11 + S2L20 Global Refinement
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, S2L20 Fab heavy chain, S2L20 Fab light chain, ...
Authors:	McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-10-29
Release date:	2021-11-17
Last modified:	2022-01-05
Method:	ELECTRON MICROSCOPY (2.4 Å)
Cite:	Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants. Science, 374, 2021

7SOD

SARS-CoV-2 S NTD B.1.617.1 kappa variant S2L20 Local Refinement
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2L20 Fab heavy chain, ...
Authors:	McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-10-29
Release date:	2021-11-17
Last modified:	2022-01-05
Method:	ELECTRON MICROSCOPY (3.2 Å)
Cite:	Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants. Science, 374, 2021

7SOA

SARS-CoV-2 S NTD B.1.617.2 delta variant + S2L20 Local Refinement
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2L20 Fab heavy chain, ...
Authors:	McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2021-10-29
Release date:	2021-11-17
Last modified:	2022-01-05
Method:	ELECTRON MICROSCOPY (3.1 Å)
Cite:	Molecular basis of immune evasion by the Delta and Kappa SARS-CoV-2 variants. Science, 374, 2021

7TM0

SARS-CoV-2 S B.1.1.529 Omicron variant + S309 + S2L20 Global Refinement
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, S2L20 Fab heavy chain, ...
Authors:	McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2022-01-19
Release date:	2022-02-02
Last modified:	2022-03-09
Method:	ELECTRON MICROSCOPY (3.1 Å)
Cite:	Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement. Science, 375, 2022

7TLY

SARS-CoV-2 S B.1.1.529 Omicron variant (RBD + S309 Local Refinement)
Descriptor:	S309 Fab heavy chain, S309 Fab light chain, Spike glycoprotein, ...
Authors:	McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2022-01-19
Release date:	2022-02-02
Last modified:	2022-03-09
Method:	ELECTRON MICROSCOPY (3 Å)
Cite:	Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement. Science, 375, 2022

7TLZ

SARS-CoV-2 S NTD B.1.1.529 Omicron variant + S309 Local Refinement
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, S2L20 Fab heavy chain, S2L20 Fab light chain, ...
Authors:	McCallum, M, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2022-01-19
Release date:	2022-02-02
Last modified:	2022-03-09
Method:	ELECTRON MICROSCOPY (3.3 Å)
Cite:	Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement. Science, 375, 2022

7TN0

SARS-CoV-2 Omicron RBD in complex with human ACE2 and S304 Fab and S309 Fab
Descriptor:	1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Angiotensin-converting enzyme 2, ...
Authors:	McCallum, M, Czudnochowski, N, Nix, J.C, Croll, T.I, SSGCID, Dillen, J.R, Snell, G, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2022-01-20
Release date:	2022-02-02
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2.85 Å)
Cite:	Structural basis of SARS-CoV-2 Omicron immune evasion and receptor engagement. Science, 375, 2022

7U0L

Crystal structure of the CCoV-HuPn-2018 RBD (domain B) in complex with canine APN
Descriptor:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Aminopeptidase N, ...
Authors:	Tortorici, M.A, Veesler, D, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2022-02-18
Release date:	2022-08-24
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (3.3 Å)
Cite:	Structure, receptor recognition, and antigenicity of the human coronavirus CCoV-HuPn-2018 spike glycoprotein. Cell, 185, 2022

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