4LBO
 
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4LBN
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4LBM
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7RGY
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7RH0
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7RH1
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7RGZ
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7RH3
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7RH4
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3T1L
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3T2T
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3T1M
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4JC1
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6EW3
 | | Crystal structure of the metallo-beta-lactamase VIM-2 with ML302F | | 分子名称: | (2Z)-2-sulfanyl-3-(2,3,6-trichlorophenyl)prop-2-enoic acid, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | | 著者 | Collins, P.M, Brem, J, McDonough, M.A, van Berkel, S.S, von Delft, F, Schofield, C.J. | | 登録日 | 2017-11-03 | | 公開日 | 2018-10-03 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.14 Å) | | 主引用文献 | Structure activity relationship studies on rhodanines and derived enethiol inhibitors of metallo-beta-lactamases.
Bioorg. Med. Chem., 26, 2018
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6F83
 | | Crystal Structure of Human Galectin-1 in Complex With Thienyl-1,2, 3-triazolyl Thiodigalactoside Inhibitor | | 分子名称: | 3-deoxy-3-[4-(thiophen-3-yl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranosyl 3-deoxy-1-thio-3-[4-(thiophen-3-yl)-1H-1,2,3-triazol-1-yl]-beta-D-galactopyranoside, Galectin-1 | | 著者 | Collins, P.M, Blanchard, H. | | 登録日 | 2017-12-12 | | 公開日 | 2019-01-30 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Aromatic heterocycle galectin-1 interactions for selective single-digit nM affinity ligands
To be published
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2NMN
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2NMO
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2NN8
 | | Crystal structure of human galectin-3 carbohydrate-recognition domain with lactose bound, at 1.35 angstrom resolution | | 分子名称: | CHLORIDE ION, GLYCEROL, Galectin-3, ... | | 著者 | Blanchard, H, Collins, P.M. | | 登録日 | 2006-10-24 | | 公開日 | 2007-03-06 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | | 主引用文献 | Slow diffusion of lactose out of galectin-3 crystals monitored by X-ray crystallography: possible implications for ligand-exchange protocols.
Acta Crystallogr.,Sect.D, 63, 2007
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3OY8
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3OYW
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5OS4
 | | Crystal structure of Aurora-A kinase in complex with an allosterically binding fragment | | 分子名称: | (3~{a}~{R},5~{S},7~{a}~{S})-5-phenyl-3~{a},4,5,6,7,7~{a}-hexahydroisoindole-1,3-dione, ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, ... | | 著者 | McIntyre, P.J, Collins, P.M, von Delft, F, Bayliss, R. | | 登録日 | 2017-08-16 | | 公開日 | 2017-11-01 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.88 Å) | | 主引用文献 | Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches.
ACS Chem. Biol., 12, 2017
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5ORL
 | | Crystal structure of Aurora-A kinase in complex with an allosterically binding fragment | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, CHLORIDE ION, ... | | 著者 | McIntyre, P.J, Collins, P.M, Vrzal, L, Birchall, K, Arnold, L.H, Mpamhanga, C, Coombs, P.J, Burgess, S.G, Richards, M.W, Winter, A, Veverka, V, von Delft, F, Merritt, A, Bayliss, R. | | 登録日 | 2017-08-16 | | 公開日 | 2017-11-01 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | | 主引用文献 | Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches.
ACS Chem. Biol., 12, 2017
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5OS1
 | | Crystal structure of Aurora-A kinase in complex with an allosterically binding fragment | | 分子名称: | 6-ethoxy-2-methyl-1,3-benzothiazole, ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, ... | | 著者 | McIntyre, P.J, Collins, P.M, von Delft, F, Bayliss, R. | | 登録日 | 2017-08-16 | | 公開日 | 2017-11-01 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches.
ACS Chem. Biol., 12, 2017
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5ORS
 | | Crystal structure of Aurora-A kinase in complex with an allosterically binding fragment | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, MAGNESIUM ION, ... | | 著者 | McIntyre, P.J, Collins, P.M, von Delft, F, Bayliss, R. | | 登録日 | 2017-08-16 | | 公開日 | 2017-11-01 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.98 Å) | | 主引用文献 | Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches.
ACS Chem. Biol., 12, 2017
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5ORW
 | | Crystal structure of Aurora-A kinase in complex with an allosterically binding fragment | | 分子名称: | 3-(4-fluoranylphenoxy)-1-thiomorpholin-4-yl-propan-1-one, ADENOSINE-5'-DIPHOSPHATE, Aurora kinase A, ... | | 著者 | McIntyre, P.J, Collins, P.M, von Delft, F, Bayliss, R. | | 登録日 | 2017-08-16 | | 公開日 | 2017-11-01 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Characterization of Three Druggable Hot-Spots in the Aurora-A/TPX2 Interaction Using Biochemical, Biophysical, and Fragment-Based Approaches.
ACS Chem. Biol., 12, 2017
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