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8EE1
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BU of 8ee1 by Molmil
KS-AT didomain from module 2 of the 6-deoxyerythronolide B synthase in complex with antibody fragment AA5
Descriptor: 6-deoxyerythronolide B synthase, AA5 antibody heavy chain, AA5 antibody light chain
Authors:Cogan, D.P, Brodsky, K.L, Guzman, K.M, Mathews, I.I, Khosla, C.
Deposit date:2022-09-06
Release date:2023-05-31
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Discovery and Characterization of Antibody Probes of Module 2 of the 6-Deoxyerythronolide B Synthase.
Biochemistry, 62, 2023
6EC7
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BU of 6ec7 by Molmil
Glutamylation domain, TbtB, from thiomuracin biosynthesis
Descriptor: Lantibiotic dehydratase domain protein
Authors:Cogan, D.P, Nair, S.K.
Deposit date:2018-08-07
Release date:2019-08-14
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Characterization of glutamyl-tRNA-dependent dehydratases using nonreactive substrate mimics.
Proc.Natl.Acad.Sci.USA, 116, 2019
5UAO
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BU of 5uao by Molmil
Crystal structure of MibH, a lathipeptide tryptophan 5-halogenase
Descriptor: CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Tryptophane-5-halogenase
Authors:Cogan, D.P, Nair, S.K.
Deposit date:2016-12-19
Release date:2017-01-25
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Two Flavoenzymes Catalyze the Post-Translational Generation of 5-Chlorotryptophan and 2-Aminovinyl-Cysteine during NAI-107 Biosynthesis.
ACS Chem. Biol., 12, 2017
6EC8
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BU of 6ec8 by Molmil
Glutamylation domain, TbtB, from thiomuracin biosynthesis bound to 5'-phosphodesmethylglutamycin
Descriptor: 3'-deoxy-3'-[(L-alpha-glutamyl)amino]adenosine 5'-(dihydrogen phosphate), Lantibiotic dehydratase domain protein
Authors:Cogan, D.P, Nair, S.K.
Deposit date:2018-08-07
Release date:2019-06-19
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (2.148 Å)
Cite:Characterization of glutamyl-tRNA-dependent dehydratases using nonreactive substrate mimics.
Proc.Natl.Acad.Sci.USA, 116, 2019
6C0H
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BU of 6c0h by Molmil
Lysinoalanine synthase, DurN, from duramycin biosynthesis bound to 1-Dha6Ala
Descriptor: GLN-DAL-CYS-ALA-PHE-GLY-PRO-PHE-DBB-PHE-VAL-CYS-BH2-GLY, Lysinoalanine synthase, POTASSIUM ION
Authors:Cogan, D.P, Nair, S.K.
Deposit date:2017-12-31
Release date:2018-09-05
Last modified:2018-10-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Substrate-assisted enzymatic formation of lysinoalanine in duramycin.
Nat. Chem. Biol., 14, 2018
6C0G
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BU of 6c0g by Molmil
Lysinoalanine synthase, DurN, from duramycin biosynthesis
Descriptor: Lysinoalanine synthase, POTASSIUM ION
Authors:Cogan, D.P, Nair, S.K.
Deposit date:2017-12-31
Release date:2018-09-05
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.145 Å)
Cite:Substrate-assisted enzymatic formation of lysinoalanine in duramycin.
Nat. Chem. Biol., 14, 2018
6C0Y
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BU of 6c0y by Molmil
Lysinoalanine synthase, DurN, from duramycin biosynthesis bound to duramycin
Descriptor: CYS-LYS-GLN-DAL-CYS-ALA-PHE-GLY-PRO-PHE-DBB-PHE-VAL-CYS-BH2-GLY-ASN-DBB-LYS, Lysinoalanine synthase, POTASSIUM ION
Authors:Cogan, D.P, Nair, S.K.
Deposit date:2018-01-03
Release date:2018-09-05
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (1.66 Å)
Cite:Substrate-assisted enzymatic formation of lysinoalanine in duramycin.
Nat. Chem. Biol., 14, 2018
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