7ULY
 
 | | MicroED structure of triclinic lysozyme | | Descriptor: | Lysozyme C, NITRATE ION | | Authors: | Clabbers, M.T.B, Martynowycz, M.W, Hattne, J, Gonen, T. | | Deposit date: | 2022-04-05 | | Release date: | 2023-03-15 | | Last modified: | 2024-10-09 | | Method: | ELECTRON CRYSTALLOGRAPHY (0.87 Å) | | Cite: | Hydrogens and hydrogen-bond networks in macromolecular MicroED data.
J Struct Biol X, 6, 2022
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7L6W
 | | SFX structure of the MyD88 TIR domain higher-order assembly | | Descriptor: | Myeloid differentiation primary response protein MyD88 | | Authors: | Clabbers, M.T.B, Holmes, S, Muusse, T.W, Vajjhala, P, Thygesen, S.J, Malde, A.K, Hunter, D.J.B, Croll, T.I, Flueckiger, L, Nanson, J.D, Rahaman, M.H, Aquila, A, Hunter, M.S, Liang, M, Yoon, C.H, Zhao, J, Zatsepin, N.A, Abbey, B, Sierecki, E, Gambin, Y, Stacey, K.J, Darmanin, C, Kobe, B, Xu, H, Ve, T. | | Deposit date: | 2020-12-24 | | Release date: | 2021-03-10 | | Last modified: | 2023-10-18 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography.
Nat Commun, 12, 2021
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7BER
 | | SFX structure of the MyD88 TIR domain higher-order assembly (solved, rebuilt and refined using an identical protocol to the MicroED structure of the MyD88 TIR domain higher-order assembly) | | Descriptor: | Myeloid differentiation primary response protein MyD88 | | Authors: | Clabbers, M.T.B, Holmes, S, Muusse, T.W, Vajjhala, P, Thygesen, S.J, Malde, A.K, Hunter, D.J.B, Croll, T.I, Nanson, J.D, Rahaman, M.H, Aquila, A, Hunter, M.S, Liang, M, Yoon, C.H, Zhao, J, Zatsepin, N.A, Abbey, B, Sierecki, E, Gambin, Y, Darmanin, C, Kobe, B, Xu, H, Ve, T. | | Deposit date: | 2020-12-24 | | Release date: | 2021-03-10 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography.
Nat Commun, 12, 2021
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7BEQ
 | | MicroED structure of the MyD88 TIR domain higher-order assembly | | Descriptor: | Myeloid differentiation primary response protein MyD88 | | Authors: | Clabbers, M.T.B, Holmes, S, Muusse, T.W, Vajjhala, P, Thygesen, S.J, Malde, A.K, Hunter, D.J.B, Croll, T.I, Nanson, J.D, Rahaman, M.H, Aquila, A, Hunter, M.S, Liang, M, Yoon, C.H, Zhao, J, Zatsepin, N.A, Abbey, B, Sierecki, E, Gambin, Y, Darmanin, C, Kobe, B, Xu, H, Ve, T. | | Deposit date: | 2020-12-24 | | Release date: | 2021-03-10 | | Last modified: | 2024-01-31 | | Method: | ELECTRON CRYSTALLOGRAPHY (3 Å) | | Cite: | MyD88 TIR domain higher-order assembly interactions revealed by microcrystal electron diffraction and serial femtosecond crystallography.
Nat Commun, 12, 2021
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5O4W
 | | Protein structure determination by electron diffraction using a single three-dimensional nanocrystal | | Descriptor: | Lysozyme C | | Authors: | Clabbers, M.T.B, van Genderen, E, Wan, W, Wiegers, E.L, Gruene, T, Abrahams, J.P. | | Deposit date: | 2017-05-31 | | Release date: | 2017-08-23 | | Last modified: | 2024-01-17 | | Method: | ELECTRON CRYSTALLOGRAPHY (2.11 Å) | | Cite: | Protein structure determination by electron diffraction using a single three-dimensional nanocrystal.
Acta Crystallogr D Struct Biol, 73, 2017
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5O4X
 | | Protein structure determination by electron diffraction using a single three-dimensional nanocrystal | | Descriptor: | Lysozyme C | | Authors: | Clabbers, M.T.B, van Genderen, E, Wan, W, Wiegers, E.L, Gruene, T, Abrahams, J.P. | | Deposit date: | 2017-05-31 | | Release date: | 2017-08-23 | | Last modified: | 2024-01-17 | | Method: | ELECTRON CRYSTALLOGRAPHY (2.11 Å) | | Cite: | Protein structure determination by electron diffraction using a single three-dimensional nanocrystal.
Acta Crystallogr D Struct Biol, 73, 2017
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8E53
 | | MicroED structure of proteinase K recorded on K3 | | Descriptor: | CALCIUM ION, Proteinase K | | Authors: | Clabbers, M.T.B, Martynowycz, M.W, Hattne, J, Nannenga, B.L, Gonen, T. | | Deposit date: | 2022-08-19 | | Release date: | 2022-09-21 | | Last modified: | 2022-10-19 | | Method: | ELECTRON CRYSTALLOGRAPHY (1.7 Å) | | Cite: | Electron-counting MicroED data with the K2 and K3 direct electron detectors.
J.Struct.Biol., 214, 2022
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8E52
 | | MicroED structure of proteinase K recorded on K2 | | Descriptor: | CALCIUM ION, Proteinase K | | Authors: | Clabbers, M.T.B, Martynowycz, M.W, Hattne, J, Nannenga, B.L, Gonen, T. | | Deposit date: | 2022-08-19 | | Release date: | 2022-09-21 | | Last modified: | 2022-10-19 | | Method: | ELECTRON CRYSTALLOGRAPHY (2.8 Å) | | Cite: | Electron-counting MicroED data with the K2 and K3 direct electron detectors.
J.Struct.Biol., 214, 2022
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8E54
 | | MicroED structure of triclinic lysozyme recorded on K3 | | Descriptor: | Lysozyme C, NITRATE ION | | Authors: | Clabbers, M.T.B, Martynowycz, M.W, Hattne, J, Nannenga, B.L, Gonen, T. | | Deposit date: | 2022-08-19 | | Release date: | 2022-09-21 | | Last modified: | 2024-10-23 | | Method: | ELECTRON CRYSTALLOGRAPHY (1.2 Å) | | Cite: | Electron-counting MicroED data with the K2 and K3 direct electron detectors.
J.Struct.Biol., 214, 2022
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6YMB
 | | MicroED structure of human carbonic anhydrase II | | Descriptor: | ZINC ION, carbonic anhydrase 2 | | Authors: | Clabbers, M.T.B, Fisher, S.Z, Coincon, M, Zou, X, Xu, H. | | Deposit date: | 2020-04-08 | | Release date: | 2020-08-12 | | Last modified: | 2024-01-24 | | Method: | ELECTRON CRYSTALLOGRAPHY (2.5 Å) | | Cite: | Visualizing drug binding interactions using microcrystal electron diffraction.
Commun Biol, 3, 2020
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6YMA
 | | MicroED structure of acetazolamide-bound human carbonic anhydrase II | | Descriptor: | 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, DIMETHYL SULFOXIDE, ZINC ION, ... | | Authors: | Clabbers, M.T.B, Fisher, S.Z, Coincon, M, Zou, X, Xu, H. | | Deposit date: | 2020-04-08 | | Release date: | 2020-08-12 | | Last modified: | 2024-01-24 | | Method: | ELECTRON CRYSTALLOGRAPHY (2.5 Å) | | Cite: | Visualizing drug binding interactions using microcrystal electron diffraction.
Commun Biol, 3, 2020
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6QRZ
 | | Crystal structure of R2-like ligand-binding oxidase from Sulfolobus acidocaldarius solved by 3D micro-crystal electron diffraction | | Descriptor: | FE (III) ION, MANGANESE (III) ION, Ribonucleoside-diphosphate reductase | | Authors: | Xu, H, Lebrette, H, Clabbers, M.T.B, Zhao, J, Griese, J.J, Zou, X, Hogbom, M. | | Deposit date: | 2019-02-20 | | Release date: | 2019-04-24 | | Last modified: | 2024-05-15 | | Method: | ELECTRON CRYSTALLOGRAPHY (3 Å) | | Cite: | Solving a new R2lox protein structure by microcrystal electron diffraction.
Sci Adv, 5, 2019
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6ZHB
 | | 3D electron diffraction structure of bovine insulin | | Descriptor: | Insulin, ZINC ION | | Authors: | Blum, T, Housset, D, Clabbers, M.T.B, van Genderen, E, Bacia-Verloop, M, Zander, U, McCarthy, A.A, Schoehn, G, Ling, W.L, Abrahams, J.P. | | Deposit date: | 2020-06-22 | | Release date: | 2021-01-27 | | Last modified: | 2024-01-24 | | Method: | ELECTRON CRYSTALLOGRAPHY (3.25 Å) | | Cite: | Statistically correcting dynamical electron scattering improves the refinement of protein nanocrystals, including charge refinement of coordinated metals.
Acta Crystallogr D Struct Biol, 77, 2021
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6ZHJ
 | | 3D electron diffraction structure of thermolysin from Bacillus thermoproteolyticus | | Descriptor: | CALCIUM ION, Thermolysin, ZINC ION | | Authors: | Blum, T, Housset, D, Clabbers, M.T.B, van Genderen, E, Schoehn, G, Ling, W.L, Abrahams, J.P. | | Deposit date: | 2020-06-23 | | Release date: | 2021-01-27 | | Last modified: | 2024-01-24 | | Method: | ELECTRON CRYSTALLOGRAPHY (3.26 Å) | | Cite: | Statistically correcting dynamical electron scattering improves the refinement of protein nanocrystals, including charge refinement of coordinated metals.
Acta Crystallogr D Struct Biol, 77, 2021
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6ZHN
 | | 3D electron diffraction structure of thaumatin from Thaumatococcus daniellii | | Descriptor: | CHLORIDE ION, Thaumatin-1 | | Authors: | Blum, T, Housset, D, Clabbers, M.T.B, van Genderen, E, Schoehn, G, Ling, W.L, Abrahams, J.P. | | Deposit date: | 2020-06-23 | | Release date: | 2021-01-27 | | Last modified: | 2024-10-16 | | Method: | ELECTRON CRYSTALLOGRAPHY (2.76 Å) | | Cite: | Statistically correcting dynamical electron scattering improves the refinement of protein nanocrystals, including charge refinement of coordinated metals.
Acta Crystallogr D Struct Biol, 77, 2021
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8FYQ
 | | MicroED structure of Proteinase K from argon milled lamellae | | Descriptor: | CALCIUM ION, NITRATE ION, Proteinase K | | Authors: | Martynowycz, M.W, Shiriaeva, A, Clabbers, M.T.B, Nicolas, W.J, Weaver, S.J, Hattne, J, Gonen, T. | | Deposit date: | 2023-01-26 | | Release date: | 2023-03-08 | | Method: | ELECTRON CRYSTALLOGRAPHY (1.4 Å) | | Cite: | A robust approach for MicroED sample preparation of lipidic cubic phase embedded membrane protein crystals.
Nat Commun, 14, 2023
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8FYR
 | | MicroED structure of Proteinase K from oxygen milled lamellae | | Descriptor: | CALCIUM ION, NITRATE ION, Proteinase K | | Authors: | Martynowycz, M.W, Shiriaeva, A, Clabbers, M.T.B, Nicolas, W.J, Weaver, S.J, Hattne, J, Gonen, T. | | Deposit date: | 2023-01-26 | | Release date: | 2023-03-08 | | Last modified: | 2024-10-23 | | Method: | ELECTRON CRYSTALLOGRAPHY (1.5 Å) | | Cite: | A robust approach for MicroED sample preparation of lipidic cubic phase embedded membrane protein crystals.
Nat Commun, 14, 2023
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8FYP
 | | MicroED structure of Proteinase K from xenon milled lamellae | | Descriptor: | CALCIUM ION, NITRATE ION, Proteinase K | | Authors: | Martynowycz, M.W, Shiriaeva, A, Clabbers, M.T.B, Nicolas, W.J, Weaver, S.J, Hattne, J, Gonen, T. | | Deposit date: | 2023-01-26 | | Release date: | 2023-03-08 | | Last modified: | 2024-10-23 | | Method: | ELECTRON CRYSTALLOGRAPHY (1.45 Å) | | Cite: | A robust approach for MicroED sample preparation of lipidic cubic phase embedded membrane protein crystals.
Nat Commun, 14, 2023
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8FYN
 | | MicroED structure of A2A from plasma milled lamellae | | Descriptor: | (2R)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, (2S)-2,3-dihydroxypropyl (9Z)-octadec-9-enoate, 4-{2-[(7-amino-2-furan-2-yl[1,2,4]triazolo[1,5-a][1,3,5]triazin-5-yl)amino]ethyl}phenol, ... | | Authors: | Martynowycz, M.W, Shiriaeva, A, Clabbers, M.T.B, Nicolas, W.J, Weaver, S.J, Hattne, J, Gonen, T. | | Deposit date: | 2023-01-26 | | Release date: | 2023-03-08 | | Last modified: | 2024-10-23 | | Method: | ELECTRON CRYSTALLOGRAPHY (2 Å) | | Cite: | A robust approach for MicroED sample preparation of lipidic cubic phase embedded membrane protein crystals.
Nat Commun, 14, 2023
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8FYS
 | | MicroED structure of Proteinase K from nitrogen milled lamellae | | Descriptor: | CALCIUM ION, Proteinase K | | Authors: | Martynowycz, M.W, Shiriaeva, A, Clabbers, M.T.B, Nicolas, W.J, Weaver, S.J, Hattne, J, Gonen, T. | | Deposit date: | 2023-01-26 | | Release date: | 2023-03-08 | | Last modified: | 2024-10-09 | | Method: | ELECTRON CRYSTALLOGRAPHY (1.8 Å) | | Cite: | A robust approach for MicroED sample preparation of lipidic cubic phase embedded membrane protein crystals.
Nat Commun, 14, 2023
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8FYO
 | | MicroED structure of Proteinase K from lamellae milled from multiple plasma sources | | Descriptor: | CALCIUM ION, NITRATE ION, Proteinase K | | Authors: | Martynowycz, M.W, Shiriaeva, A, Clabbers, M.T.B, Nicolas, W.J, Weaver, S.J, Hattne, J, Gonen, T. | | Deposit date: | 2023-01-26 | | Release date: | 2023-05-24 | | Last modified: | 2024-10-23 | | Method: | ELECTRON CRYSTALLOGRAPHY (1.39 Å) | | Cite: | A robust approach for MicroED sample preparation of lipidic cubic phase embedded membrane protein crystals.
Nat Commun, 14, 2023
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7SKX
 | | Ab initio structure of proteinase K from electron-counted MicroED data | | Descriptor: | 5-amino-2,4,6-triiodobenzene-1,3-dicarboxylic acid, CALCIUM ION, Proteinase K | | Authors: | Martynowycz, M.W, Clabbers, M.T.B, Hattne, J, Gonen, T. | | Deposit date: | 2021-10-21 | | Release date: | 2022-06-08 | | Last modified: | 2024-10-16 | | Method: | ELECTRON CRYSTALLOGRAPHY (1.5 Å) | | Cite: | Ab initio phasing macromolecular structures using electron-counted MicroED data.
Nat.Methods, 19, 2022
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7SKW
 | | Ab initio structure of triclinic lysozyme from electron-counted MicroED data | | Descriptor: | Lysozyme C, NITRATE ION | | Authors: | Martynowycz, M.W, Clabbers, M.T.B, Hattne, J, Gonen, T. | | Deposit date: | 2021-10-21 | | Release date: | 2022-06-08 | | Last modified: | 2024-10-09 | | Method: | ELECTRON CRYSTALLOGRAPHY (0.87 Å) | | Cite: | Ab initio phasing macromolecular structures using electron-counted MicroED data.
Nat.Methods, 19, 2022
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7SW4
 | | MicroED structure of proteinase K from a 540 nm thick lamella measured at 200 kV | | Descriptor: | Proteinase K | | Authors: | Martynowycz, M.W, Clabbers, M.T.B, Unge, J, Hattne, J, Gonen, T. | | Deposit date: | 2021-11-19 | | Release date: | 2022-09-07 | | Last modified: | 2024-10-09 | | Method: | ELECTRON CRYSTALLOGRAPHY (2.4 Å) | | Cite: | Benchmarking the ideal sample thickness in cryo-EM.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7SW9
 | | MicroED structure of proteinase K from a 170 nm thick lamella measured at 300 kV | | Descriptor: | Proteinase K | | Authors: | Martynowycz, M.W, Clabbers, M.T.B, Unge, J, Hattne, J, Gonen, T. | | Deposit date: | 2021-11-19 | | Release date: | 2022-09-07 | | Last modified: | 2023-10-18 | | Method: | ELECTRON CRYSTALLOGRAPHY (2.1 Å) | | Cite: | Benchmarking the ideal sample thickness in cryo-EM.
Proc.Natl.Acad.Sci.USA, 118, 2021
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