6NYN
| Helicobacter pylori Vacuolating Cytotoxin A Oligomeric Assembly 2e (OA-2e) | Descriptor: | Vacuolating cytotoxin autotransporter | Authors: | Zhang, K, Zhang, H, Li, S, Au, S, Chiu, W. | Deposit date: | 2019-02-11 | Release date: | 2019-03-27 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Cryo-EM structures ofHelicobacter pylorivacuolating cytotoxin A oligomeric assemblies at near-atomic resolution. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6OJN
| Comparative Model of SGIV Major Coat Protein (MCP) Trimer Based on Cryo-EM Map | Descriptor: | Major capsid protein | Authors: | Pintilie, G, Chen, D.-H, Tran, B.N, Jakana, J, Wu, J, Hew, C.L, Chiu, W. | Deposit date: | 2019-04-11 | Release date: | 2019-06-12 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (8.6 Å) | Cite: | Segmentation and Comparative Modeling in an 8.6- angstrom Cryo-EM Map of the Singapore Grouper Iridovirus. Structure, 27, 2019
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6POM
| Cryo-EM structure of the full-length Bacillus subtilis glyQS T-box riboswitch in complex with tRNA-Gly | Descriptor: | T-box GlyQS leader (155-MER), tRNAGly (75-MER) | Authors: | Li, S, Su, Z, Zhang, J, Chiu, W. | Deposit date: | 2019-07-04 | Release date: | 2019-11-20 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.9 Å) | Cite: | Structural basis of amino acid surveillance by higher-order tRNA-mRNA interactions. Nat.Struct.Mol.Biol., 26, 2019
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2M5S
| High-resolution NMR structure and cryo-EM imaging support multiple functional roles for the accessory I-domain of phage P22 coat protein | Descriptor: | Coat protein | Authors: | Rizzo, A.A, Suhanovsky, M.M, Baker, M.L, Fraser, L.C.R, Jones, L.M, Rempel, D.L, Gross, M.L, Chiu, W, Alexandrescu, A.T, Teschke, C.M. | Deposit date: | 2013-03-05 | Release date: | 2014-03-05 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Multiple Functional Roles of the Accessory I-Domain of Bacteriophage P22 Coat Protein Revealed by NMR Structure and CryoEM Modeling. Structure, 22, 2014
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2L1F
| Structure of a conserved retroviral RNA packaging element by NMR spectroscopy and cryo-electron tomography | Descriptor: | RNA (65-MER), RNA (66-MER) | Authors: | Summers, M.F, Irobalieva, R.N, Tolbert, B, Smalls-Manty, A, Iyalla, K, Loeliger, K, D'Souza, V, Khant, H, Schmid, M, Garcia, E, Telesnitsky, A, Chiu, W, Miyazaki, Y. | Deposit date: | 2010-07-28 | Release date: | 2010-10-27 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | Structure of a conserved retroviral RNA packaging element by NMR spectroscopy and cryo-electron tomography. J.Mol.Biol., 404, 2010
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7TUB
| The beta-tubulin folding intermediate IV | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | Authors: | Zhao, Y, Frydman, J, Chiu, W. | Deposit date: | 2022-02-02 | Release date: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT. Cell, 185, 2022
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7TRG
| The beta-tubulin folding intermediate I | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | Authors: | Zhao, Y, Frydman, J, Chiu, W. | Deposit date: | 2022-01-28 | Release date: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT. Cell, 185, 2022
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7TTN
| The beta-tubulin folding intermediate II | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | Authors: | Zhao, Y, Frydman, J, Chiu, W. | Deposit date: | 2022-02-01 | Release date: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT. Cell, 185, 2022
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7TTT
| The beta-tubulin folding intermediate III | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, MAGNESIUM ION, ... | Authors: | Zhao, Y, Frydman, J, Chiu, W. | Deposit date: | 2022-02-01 | Release date: | 2022-12-28 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT. Cell, 185, 2022
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7XSN
| Native Tetrahymena ribozyme conformation | Descriptor: | RNA (387-MER) | Authors: | Li, S, Palo, M, Pintilie, G, Zhang, X, Su, Z, Kappel, K, Chiu, W, Zhang, K, Das, R. | Deposit date: | 2022-05-14 | Release date: | 2022-08-03 | Last modified: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (3.01 Å) | Cite: | Topological crossing in the misfolded Tetrahymena ribozyme resolved by cryo-EM. Proc.Natl.Acad.Sci.USA, 119, 2022
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7XSM
| Misfolded Tetrahymena ribozyme conformation 3 | Descriptor: | RNA (388-MER) | Authors: | Li, S, Palo, M, Pintilie, G, Zhang, X, Su, Z, Kappel, K, Chiu, W, Zhang, K, Das, R. | Deposit date: | 2022-05-14 | Release date: | 2022-08-03 | Last modified: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (4.01 Å) | Cite: | Topological crossing in the misfolded Tetrahymena ribozyme resolved by cryo-EM. Proc.Natl.Acad.Sci.USA, 119, 2022
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7XSL
| Misfolded Tetrahymena ribozyme conformation 2 | Descriptor: | RNA (388-MER) | Authors: | Li, S, Palo, M, Pintilie, G, Zhang, X, Su, Z, Kappel, K, Chiu, W, Zhang, K, Das, R. | Deposit date: | 2022-05-14 | Release date: | 2022-08-03 | Last modified: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (3.84 Å) | Cite: | Topological crossing in the misfolded Tetrahymena ribozyme resolved by cryo-EM. Proc.Natl.Acad.Sci.USA, 119, 2022
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7XSK
| Misfolded Tetrahymena ribozyme conformation 1 | Descriptor: | RNA (388-MER) | Authors: | Li, S, Palo, M, Pintilie, G, Zhang, X, Su, Z, Kappel, K, Chiu, W, Zhang, K, Das, R. | Deposit date: | 2022-05-14 | Release date: | 2022-08-03 | Last modified: | 2022-10-05 | Method: | ELECTRON MICROSCOPY (3.53 Å) | Cite: | Topological crossing in the misfolded Tetrahymena ribozyme resolved by cryo-EM. Proc.Natl.Acad.Sci.USA, 119, 2022
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5NG5
| multi-drug efflux; membrane transport; RND superfamily; Drug resistance | Descriptor: | 6-[2-(3,4-dimethoxyphenyl)ethylsulfanyl]-8-[4-(2-methoxyethyl)piperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile, Multidrug efflux pump accessory protein AcrZ, Multidrug efflux pump subunit AcrA, ... | Authors: | Wang, Z, Fan, G, Hryc, C.F, Blaza, J.N, Serysheva, I.I, Schmid, M.F, Chiu, W, Luisi, B.F, Du, D. | Deposit date: | 2017-03-16 | Release date: | 2017-04-19 | Last modified: | 2017-08-02 | Method: | ELECTRON MICROSCOPY (6.5 Å) | Cite: | An allosteric transport mechanism for the AcrAB-TolC Multidrug Efflux Pump. Elife, 6, 2017
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3J0C
| Models of E1, E2 and CP of Venezuelan Equine Encephalitis Virus TC-83 strain restrained by a near atomic resolution cryo-EM map | Descriptor: | Capsid protein, E1 envelope glycoprotein, E2 envelope glycoprotein | Authors: | Zhang, R, Hryc, C.F, Cong, Y, Liu, X, Jakana, J, Gorchakov, R, Baker, M.L, Weaver, S.C, Chiu, W. | Deposit date: | 2011-06-22 | Release date: | 2011-08-24 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (4.8 Å) | Cite: | 4.4 A cryo-EM structure of an enveloped alphavirus Venezuelan equine encephalitis virus. Embo J., 30, 2011
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7WU7
| Prefoldin-tubulin-TRiC complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Prefoldin subunit 1, Prefoldin subunit 2, ... | Authors: | Gestaut, D, Zhao, Y, Park, J, Ma, B, Leitner, A, Collier, M, Pintilie, G, Roh, S.-H, Chiu, W, Frydman, J. | Deposit date: | 2022-02-07 | Release date: | 2022-12-21 | Method: | ELECTRON MICROSCOPY (3.85 Å) | Cite: | Structural visualization of the tubulin folding pathway directed by human chaperonin TRiC/CCT. Cell, 185, 2022
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3J0G
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6UKT
| Cryo-EM structure of mammalian Ric-8A:Galpha(i):nanobody complex | Descriptor: | Guanine nucleotide-binding protein G(i) subunit alpha-1, NB8109, NB8117, ... | Authors: | Mou, T.C, Zhang, K, Johnston, J.D, Chiu, W, Sprang, S.R. | Deposit date: | 2019-10-05 | Release date: | 2020-03-11 | Method: | ELECTRON MICROSCOPY (3.87 Å) | Cite: | Structure of the G protein chaperone and guanine nucleotide exchange factor Ric-8A bound to G alpha i1. Nat Commun, 11, 2020
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6V5B
| Human Drosha and DGCR8 in complex with Primary MicroRNA (MP/RNA complex) - Active state | Descriptor: | CALCIUM ION, Microprocessor complex subunit DGCR8, Pri-miR-16-2 (78-MER), ... | Authors: | Partin, A, Zhang, K, Jeong, B, Herrell, E, Li, S, Chiu, W, Nam, Y. | Deposit date: | 2019-12-04 | Release date: | 2020-04-08 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Cryo-EM Structures of Human Drosha and DGCR8 in Complex with Primary MicroRNA. Mol.Cell, 78, 2020
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6UES
| Apo SAM-IV Riboswitch | Descriptor: | RNA (119-MER) | Authors: | Zhang, K, Li, S, Kappel, K, Pintilie, G, Su, Z, Mou, T, Schmid, M, Das, R, Chiu, W. | Deposit date: | 2019-09-23 | Release date: | 2019-12-18 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.7 Å) | Cite: | Cryo-EM structure of a 40 kDa SAM-IV riboswitch RNA at 3.7 angstrom resolution. Nat Commun, 10, 2019
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6UET
| SAM-bound SAM-IV riboswitch | Descriptor: | RNA (119-MER), S-ADENOSYLMETHIONINE | Authors: | Zhang, K, Li, S, Kappel, K, Pintilie, G, Su, Z, Mou, T, Schmid, M, Das, R, Chiu, W. | Deposit date: | 2019-09-23 | Release date: | 2019-12-18 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.1 Å) | Cite: | Cryo-EM structure of a 40 kDa SAM-IV riboswitch RNA at 3.7 angstrom resolution. Nat Commun, 10, 2019
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6VQX
| Type I-F CRISPR-Csy complex with its inhibitor AcrF6 | Descriptor: | AcrF6, CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, ... | Authors: | Zhang, K, Li, S, Pintilie, G, Zhu, Y, Huang, Z, Chiu, W. | Deposit date: | 2020-02-06 | Release date: | 2020-03-11 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.15 Å) | Cite: | Inhibition mechanisms of AcrF9, AcrF8, and AcrF6 against type I-F CRISPR-Cas complex revealed by cryo-EM. Proc.Natl.Acad.Sci.USA, 117, 2020
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6VQV
| Type I-F CRISPR-Csy complex with its inhibitor AcrF9 | Descriptor: | AcrF9, CRISPR-associated endonuclease Cas6/Csy4, CRISPR-associated protein Csy1, ... | Authors: | Zhang, K, Li, S, Pintilie, G, Zhu, Y, Huang, Z, Chiu, W. | Deposit date: | 2020-02-06 | Release date: | 2020-03-11 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (2.57 Å) | Cite: | Inhibition mechanisms of AcrF9, AcrF8, and AcrF6 against type I-F CRISPR-Cas complex revealed by cryo-EM. Proc.Natl.Acad.Sci.USA, 117, 2020
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7KIP
| A 3.4 Angstrom cryo-EM structure of the human coronavirus spike trimer computationally derived from vitrified NL63 virus particles | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | Authors: | Zhang, K, Li, S, Pintilie, G, Chmielewski, D, Schmid, M, Simmons, G, Jin, J, Chiu, W. | Deposit date: | 2020-10-24 | Release date: | 2020-11-11 | Method: | ELECTRON MICROSCOPY (3.39 Å) | Cite: | A 3.4- angstrom cryo-EM structure of the human coronavirus spike trimer computationally derived from vitrified NL63 virus particles. Biorxiv, 2020
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6V5C
| Human Drosha and DGCR8 in complex with Primary MicroRNA (MP/RNA complex) - partially docked state | Descriptor: | Microprocessor complex subunit DGCR8, Pri-miR-16-2 (66-MER), Ribonuclease 3 | Authors: | Partin, A, Zhang, K, Jeong, B, Herrell, E, Li, S, Chiu, W, Nam, Y. | Deposit date: | 2019-12-04 | Release date: | 2020-04-08 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (4.4 Å) | Cite: | Cryo-EM Structures of Human Drosha and DGCR8 in Complex with Primary MicroRNA. Mol.Cell, 78, 2020
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