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Choline Kinase alpha acts through a double-displacement kinetic mechanism involving enzyme isomerisation, as determined through enzyme and inhibitor kinetics and structural biology
分子名称:	(3R)-1-azabicyclo[2.2.2]oct-3-yl[bis(5-chlorothiophen-2-yl)]methanol, Choline kinase alpha, SULFATE ION
著者	Brown, K, Hudson, C, Charlton, P, Pollard, J.
登録日	2012-01-12
公開日	2013-04-17
最終更新日	2024-02-28
実験手法	X-RAY DIFFRACTION (2.4 Å)
主引用文献	Kinetic and mechanistic characterisation of Choline Kinase-alpha. Biochim.Biophys.Acta, 1834, 2013

CRYSTAL STRUCTURE ANALYSIS OF D(CG(5-BRU)ACG) COMPLEXES TO A PHENAZINE
分子名称:	5'-D(CPGP(BRO)UPAPCPG)-3', 9-BROMO-PHENAZINE-1-CARBOXYLIC ACID (2-DIMETHYLAMINO-ETHYL)-AMIDE, BROMIDE ION, ...
著者	Cardin, C.J, Denny, W.A, Hobbs, J.R, Thorpe, J.H.
登録日	2000-02-14
公開日	2001-01-03
最終更新日	2024-02-07
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Guanine specific binding at a DNA junction formed by d[CG(5-BrU)ACG](2) with a topoisomerase poison in the presence of Co(2+) ions. Biochemistry, 39, 2000