1EG6

CRYSTAL STRUCTURE ANALYSIS OF D(CG(5-BRU)ACG) COMPLEXES TO A PHENAZINE

Summary for 1EG6

Descriptor5'-D(*CP*GP*(BRO)UP*AP*CP*G)-3', COBALT (III) ION, BROMIDE ION, ... (5 entities in total)
Functional Keywordsdrug-dna complex, intercalation, major groove binding, double helix, dna
Total number of polymer chains2
Total molecular weight4241.3
Authors
Cardin, C.J.,Denny, W.A.,Hobbs, J.R.,Thorpe, J.H. (deposition date: 2000-02-14, release date: 2001-01-03, Last modification date: 2011-07-13)
Primary citation
Thorpe, J.H.,Hobbs, J.R.,Todd, A.K.,Denny, W.A.,Charlton, P.,Cardin, C.J.
Guanine specific binding at a DNA junction formed by d[CG(5-BrU)ACG](2) with a topoisomerase poison in the presence of Co(2+) ions.
Biochemistry, 39:15055-15061, 2000
PubMed: 11106483 (PDB entries with the same primary citation)
DOI: 10.1021/bi001749p
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2 Å)
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Structure validation

Clashscore47MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution