3IEX
 
 | | Schistosoma Purine nucleoside phosphorylase in complex with guanosine | | Descriptor: | ACETATE ION, DIMETHYL SULFOXIDE, GUANOSINE, ... | | Authors: | Castilho, M.S, Pereira, H.M, Oliva, G, Andricopulo, A.D. | | Deposit date: | 2009-07-23 | | Release date: | 2010-03-16 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.05 Å) | | Cite: | Structural basis for selective inhibition of purine nucleoside phosphorylase from Schistosoma mansoni: kinetic and structural studies
Bioorg.Med.Chem., 18, 2010
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1ML3
 | | Evidences for a flip-flop catalytic mechanism of Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase, from its crystal structure in complex with reacted irreversible inhibitor 2-(2-phosphono-ethyl)-acrylic acid 4-nitro-phenyl ester | | Descriptor: | (3-FORMYL-BUT-3-ENYL)-PHOSPHONIC ACID, Glyceraldehyde 3-phosphate dehydrogenase, glycosomal, ... | | Authors: | Castilho, M.S, Pavao, F, Oliva, G. | | Deposit date: | 2002-08-29 | | Release date: | 2003-07-08 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Evidence for the Two Phosphate Binding Sites of an Analogue of the Thioacyl Intermediate for the Trypanosoma cruzi Glyceraldehyde-3-phosphate Dehydrogenase-Catalyzed Reaction, from Its Crystal Structure.
Biochemistry, 42, 2003
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1QXS
 | | CRYSTAL STRUCTURE OF Trypanosoma cruzi GLYCERALDEHYDE-3- PHOSPHATE DEHYDROGENASE COMPLEXED WITH AN ANALOGUE OF 1,3- BisPHOSPHO-D-GLYCERIC ACID | | Descriptor: | 3-HYDROXY-2-OXO-4-PHOPHONOXY- BUTYL)-PHOSPHONIC ACID, Glyceraldehyde 3-phosphate dehydrogenase, glycosomal, ... | | Authors: | Castilho, M.S, Pavao, F, Oliva, G. | | Deposit date: | 2003-09-08 | | Release date: | 2004-05-11 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.75 Å) | | Cite: | Crystal structure of Trypanosoma cruzi glyceraldehyde-3-phosphate dehydrogenase complexed with an analogue of 1,3-bisphospho-d-glyceric acid.
Eur.J.Biochem., 270, 2003
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3FNQ
 | | Crystal structure of schistosoma purine nucleoside phosphorylase in complex with hypoxanthine | | Descriptor: | DIMETHYL SULFOXIDE, HYPOXANTHINE, Purine-nucleoside phosphorylase, ... | | Authors: | Castilho, M.S, Pereira, H.M, Garratt, R.C, Oliva, G. | | Deposit date: | 2008-12-26 | | Release date: | 2009-02-24 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Adenosine binding to low-molecular-weight purine nucleoside phosphorylase: the structural basis for recognition based on its complex with the enzyme from Schistosoma mansoni.
Acta Crystallogr.,Sect.D, 66, 2010
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3DJF
 | | Crystal Structure of Schistosoma mansoni Purine Nucleoside Phosphorylase in a complex with BCX-34 | | Descriptor: | 2-amino-7-(pyridin-3-ylmethyl)-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one, DIMETHYL SULFOXIDE, Purine-nucleoside phosphorylase, ... | | Authors: | Postigo, M.P, Pereira, H.M, Oliva, G, Andricopulo, A.D. | | Deposit date: | 2008-06-23 | | Release date: | 2009-06-30 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (2.302 Å) | | Cite: | Structural basis for selective inhibition of purine nucleoside phosphorylase from Schistosoma mansoni: kinetic and structural studies.
Bioorg.Med.Chem., 18, 2010
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1K3T
 | | Structure of Glycosomal Glyceraldehyde-3-Phosphate Dehydrogenase from Trypanosoma cruzi Complexed with Chalepin, a Coumarin Derivative Inhibitor | | Descriptor: | 6-(1,1-DIMETHYLALLYL)-2-(1-HYDROXY-1-METHYLETHYL)-2,3-DIHYDRO-7H-FURO[3,2-G]CHROMEN-7-ONE, Glyceraldehyde-3-phosphate dehydrogenase | | Authors: | Pavao, F. | | Deposit date: | 2001-10-04 | | Release date: | 2002-06-19 | | Last modified: | 2024-04-03 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Structure of Trypanosoma cruzi glycosomal glyceraldehyde-3-phosphate dehydrogenase complexed with chalepin, a natural product inhibitor, at 1.95 A resolution.
FEBS Lett., 520, 2002
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3E9R
 | | Crystal structure of purine nucleoside phosphorylase from Schistosoma mansoni in complex with adenine | | Descriptor: | ACETATE ION, ADENINE, DIMETHYL SULFOXIDE, ... | | Authors: | Pereira, H.M, Rezende, M.M, Oliva, G, Garratt, R.C. | | Deposit date: | 2008-08-23 | | Release date: | 2009-09-01 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (1.85 Å) | | Cite: | Adenosine binding to low-molecular-weight purine nucleoside phosphorylase: the structural basis for recognition based on its complex with the enzyme from Schistosoma mansoni.
Acta Crystallogr.,Sect.D, 66, 2010
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3FAZ
 | | Crystal structure of Schistosoma mansoni purine nucleoside phosphorylase in complex with inosine | | Descriptor: | INOSINE, Purine-nucleoside phosphorylase, SULFATE ION | | Authors: | Pereira, H.M, Garratt, R.C, Oliva, G. | | Deposit date: | 2008-11-18 | | Release date: | 2009-11-24 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Adenosine binding to low-molecular-weight purine nucleoside phosphorylase: the structural basis for recognition based on its complex with the enzyme from Schistosoma mansoni.
Acta Crystallogr.,Sect.D, 66, 2010
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3F8W
 | | Crystal structure of Schistosoma mansoni purine nucleoside phosphorylase in complex with adenosine | | Descriptor: | ADENOSINE, DIMETHYL SULFOXIDE, Purine-nucleoside phosphorylase, ... | | Authors: | Pereira, H.M, Rezende, M.M, Garratt, R.C, Oliva, G. | | Deposit date: | 2008-11-13 | | Release date: | 2009-11-24 | | Last modified: | 2023-09-06 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Adenosine binding to low-molecular-weight purine nucleoside phosphorylase: the structural basis for recognition based on its complex with the enzyme from Schistosoma mansoni.
Acta Crystallogr.,Sect.D, 66, 2010
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