1K3T

Structure of Glycosomal Glyceraldehyde-3-Phosphate Dehydrogenase from Trypanosoma cruzi Complexed with Chalepin, a Coumarin Derivative Inhibitor

Summary for 1K3T

Entry DOI	10.2210/pdb1k3t/pdb
Descriptor	Glyceraldehyde-3-phosphate dehydrogenase, 6-(1,1-DIMETHYLALLYL)-2-(1-HYDROXY-1-METHYLETHYL)-2,3-DIHYDRO-7H-FURO[3,2-G]CHROMEN-7-ONE (3 entities in total)
Functional Keywords	apo-protein, ggapdh-chalepin complex, glycosome, trypanosoma cruzi, oxidoreductase
Biological source	Trypanosoma cruzi
Cellular location	Glycosome: P22513
Total number of polymer chains	4
Total formula weight	156764.53
Authors	Pavao, F. (deposition date: 2001-10-04, release date: 2002-06-19, Last modification date: 2024-04-03)
Primary citation	Pavao, F.,Castilho, M.S.,Pupo, M.T.,Dias, R.L.,Correa, A.G.,Fernandes, J.B.,da Silva, M.F.,Mafezoli, J.,Vieira, P.C.,Oliva, G. Structure of Trypanosoma cruzi glycosomal glyceraldehyde-3-phosphate dehydrogenase complexed with chalepin, a natural product inhibitor, at 1.95 A resolution. FEBS Lett., 520:13-17, 2002 Cited by PubMed: 12044862 DOI: 10.1016/S0014-5793(02)02700-X PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.95 Å)

Structure validation