8PQV
| Cytoplasmic dynein-1 motor domain in post-powerstroke state | Descriptor: | Cytoplasmic dynein 1 heavy chain 1 | Authors: | Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. | Deposit date: | 2023-07-12 | Release date: | 2024-03-27 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (4 Å) | Cite: | Molecular mechanism of dynein-dynactin complex assembly by LIS1. Science, 383, 2024
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8PR4
| Dynactin pointed end bound to JIP3 | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, Arp11, C-Jun-amino-terminal kinase-interacting protein 3, ... | Authors: | Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. | Deposit date: | 2023-07-12 | Release date: | 2024-03-27 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Molecular mechanism of dynein-dynactin complex assembly by LIS1. Science, 383, 2024
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8PQZ
| Cytoplasmic dynein-1 A1/A2 motor domains bound to LIS1 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1, ... | Authors: | Singh, K, Lau, C.K, Manigrasso, G, Gassmann, R, Carter, A.P. | Deposit date: | 2023-07-12 | Release date: | 2024-03-27 | Last modified: | 2024-04-10 | Method: | ELECTRON MICROSCOPY (5.5 Å) | Cite: | Molecular mechanism of dynein-dynactin complex assembly by LIS1. Science, 383, 2024
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8OH4
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5NVS
| Human cytoplasmic dynein-1 tail in the twisted N-terminus state | Descriptor: | LC8, N-terminal dimerization domain, Robl, ... | Authors: | Zhang, K, Foster, H.E, Carter, A.P. | Deposit date: | 2017-05-04 | Release date: | 2017-06-28 | Last modified: | 2024-07-10 | Method: | ELECTRON MICROSCOPY (8.4 Å) | Cite: | Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated. Cell, 169, 2017
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5NW4
| Human cytoplasmic dynein-1 bound to dynactin and an N-terminal construct of BICD2 | Descriptor: | Arp1, Arp11, BICD2N, ... | Authors: | Zhang, K, Foster, H.E, Carter, A.P. | Deposit date: | 2017-05-05 | Release date: | 2017-08-02 | Last modified: | 2018-11-21 | Method: | ELECTRON MICROSCOPY (8.7 Å) | Cite: | Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated. Cell, 169, 2017
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5NVU
| Full length human cytoplasmic dynein-1 in the phi-particle conformation | Descriptor: | Dynein intermediate chain, Dynein light intermediate chain, Dynein motor domain, ... | Authors: | Zhang, K, Foster, H.E, Carter, A.P. | Deposit date: | 2017-05-04 | Release date: | 2017-08-09 | Last modified: | 2017-09-06 | Method: | ELECTRON MICROSCOPY (15 Å) | Cite: | Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated. Cell, 169, 2017
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5NUG
| Motor domains from human cytoplasmic dynein-1 in the phi-particle conformation | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1, ... | Authors: | Zhang, K, Foster, H.E, Carter, A.P. | Deposit date: | 2017-04-30 | Release date: | 2017-06-28 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Cryo-EM Reveals How Human Cytoplasmic Dynein Is Auto-inhibited and Activated. Cell, 169, 2017
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5OWO
| Human cytoplasmic Dynein N-Terminus dimerization domain at 1.8 Angstrom resolution | Descriptor: | CALCIUM ION, Cytoplasmic dynein 1 heavy chain 1, GLYCEROL, ... | Authors: | Urnavicius, L, Lau, C.K, Elshenawy, M.M, Morales-Rios, E, Motz, C, Yildiz, A, Carter, A.P. | Deposit date: | 2017-09-01 | Release date: | 2018-07-11 | Last modified: | 2022-03-30 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Cryo-EM shows how dynactin recruits two dyneins for faster movement. Nature, 554, 2018
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7Z8K
| Cytoplasmic dynein (A1) bound to BICDR1 | Descriptor: | ARP1 actin related protein 1 homolog A, BICD family-like cargo adapter 1, Cytoplasmic dynein 1 heavy chain 1, ... | Authors: | Chaaban, S, Carter, A.P. | Deposit date: | 2022-03-17 | Release date: | 2022-07-27 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (4.37 Å) | Cite: | Structure of dynein-dynactin on microtubules shows tandem adaptor binding. Nature, 610, 2022
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7Z8L
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7Z8H
| Cytoplasmic dynein-1 motor domain AAA1, AAA2, and AAA3 subunits | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1, ... | Authors: | Chaaban, S, Carter, A.P. | Deposit date: | 2022-03-17 | Release date: | 2022-07-27 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.41 Å) | Cite: | Structure of dynein-dynactin on microtubules shows tandem adaptor binding. Nature, 610, 2022
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7Z8F
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7Z8J
| Cytoplasmic dynein (A2) bound to BICDR1 | Descriptor: | BICD family-like cargo adapter 1, Cytoplasmic dynein 1 heavy chain 1, Cytoplasmic dynein 1 intermediate chain 2, ... | Authors: | Chaaban, S, Carter, A.P. | Deposit date: | 2022-03-17 | Release date: | 2022-07-27 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.93 Å) | Cite: | Structure of dynein-dynactin on microtubules shows tandem adaptor binding. Nature, 610, 2022
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7Z8G
| Cytoplasmic dynein-1 motor domain | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Cytoplasmic dynein 1 heavy chain 1, ... | Authors: | Chaaban, S, Carter, A.P. | Deposit date: | 2022-03-17 | Release date: | 2022-07-27 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.52 Å) | Cite: | Structure of dynein-dynactin on microtubules shows tandem adaptor binding. Nature, 610, 2022
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7Z8M
| The pointed end complex of dynactin bound to BICDR1 | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ARP1 actin related protein 1 homolog A, ... | Authors: | Chaaban, S, Carter, A.P. | Deposit date: | 2022-03-17 | Release date: | 2022-07-27 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.37 Å) | Cite: | Structure of dynein-dynactin on microtubules shows tandem adaptor binding. Nature, 610, 2022
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7Z8I
| The barbed end complex of dynactin bound to BICDR1 and the cytoplasmic dynein tails (A2, B1, B2) | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ARP1 actin related protein 1 homolog A, BICD family-like cargo adapter 1, ... | Authors: | Chaaban, S, Carter, A.P. | Deposit date: | 2022-03-17 | Release date: | 2022-08-17 | Last modified: | 2024-07-24 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Structure of dynein-dynactin on microtubules shows tandem adaptor binding. Nature, 610, 2022
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4AI6
| Dynein Motor Domain - ADP complex | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, GLUTATHIONE S-TRANSFERASE CLASS-MU 26 KDA ISOZYME, ... | Authors: | Schmidt, H, Gleave, E.S, Carter, A.P. | Deposit date: | 2012-02-08 | Release date: | 2012-03-14 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | Insights Into Dynein Motor Domain Function from a 3.3 Angstrom Crystal Structure Nat.Struct.Mol.Biol., 19, 2012
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4AKI
| Dynein Motor Domain - LuAc derivative | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GLUTATHIONE S-TRANSFERASE CLASS-MU 26 KDA ISOZYME, DYNEIN HEAVY CHAIN CYTOPLASMIC, ... | Authors: | Schmidt, H, Gleave, E.S, Carter, A.P. | Deposit date: | 2012-02-22 | Release date: | 2012-03-14 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Insights Into Dynein Motor Domain Function from a 3.3 Angstrom Crystal Structure Nat.Struct.Mol.Biol., 19, 2012
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4AKH
| Dynein Motor Domain - AMPPNP complex | Descriptor: | ADENOSINE-5'-TRIPHOSPHATE, GLUTATHIONE S-TRANSFERASE CLASS-MU 26 KDA ISOZYME, DYNEIN HEAVY CHAIN CYTOPLASMIC, ... | Authors: | Schmidt, H, Gleave, E.S, Carter, A.P. | Deposit date: | 2012-02-22 | Release date: | 2012-03-14 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Insights Into Dynein Motor Domain Function from a 3.3 Angstrom Crystal Structure Nat.Struct.Mol.Biol., 19, 2012
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7XU2
| Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-2 Conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | Authors: | Qu, K, Chen, Q, Ciazynska, K.A, Liu, B, Zhang, X, Wang, J, He, Y, Guan, J, He, J, Liu, T, Zhang, X, Carter, A.P, Xiong, X, Briggs, J.A.G. | Deposit date: | 2022-05-18 | Release date: | 2022-07-20 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike. Plos Pathog., 18, 2022
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7XU0
| Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-211 Conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | Authors: | Qu, K, Chen, Q, Ciazynska, K.A, Liu, B, Zhang, X, Wang, J, He, Y, Guan, J, He, J, Liu, T, Zhang, X, Carter, A.P, Xiong, X, Briggs, J.A.G. | Deposit date: | 2022-05-18 | Release date: | 2022-07-20 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike. Plos Pathog., 18, 2022
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7XTZ
| Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-1 Conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | Authors: | Qu, K, Chen, Q, Ciazynska, K.A, Liu, B, Zhang, X, Wang, J, He, Y, Guan, J, He, J, Liu, T, Zhang, X, Carter, A.P, Xiong, X, Briggs, J.A.G. | Deposit date: | 2022-05-18 | Release date: | 2022-07-20 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike. Plos Pathog., 18, 2022
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7XU1
| Structure of SARS-CoV-2 Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-122 Conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | Authors: | Qu, K, Chen, Q, Ciazynska, K.A, Liu, B, Zhang, X, Wang, J, He, Y, Guan, J, He, J, Liu, T, Zhang, X, Carter, A.P, Xiong, X, Briggs, J.A.G. | Deposit date: | 2022-05-18 | Release date: | 2022-07-20 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike. Plos Pathog., 18, 2022
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7XU4
| Structure of SARS-CoV-2 D614G Spike Protein with Engineered x3 Disulfide (x3(D427C, V987C) and single Arg S1/S2 cleavage site), Locked-2 Conformation | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BILIVERDINE IX ALPHA, ... | Authors: | Qu, K, Chen, Q, Ciazynska, K.A, Liu, B, Zhang, X, Wang, J, He, Y, Guan, J, He, J, Liu, T, Zhang, X, Carter, A.P, Xiong, X, Briggs, J.A.G. | Deposit date: | 2022-05-18 | Release date: | 2022-07-20 | Last modified: | 2022-08-17 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike. Plos Pathog., 18, 2022
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