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1RXS
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BU of 1rxs by Molmil
E. coli uridine phosphorylase: 2'-deoxyuridine phosphate complex
分子名称: 2'-DEOXYURIDINE, META VANADATE, PHOSPHATE ION, ...
著者Caradoc-Davies, T.T, Cutfield, S.M, Lamont, I.L, Cutfield, J.F.
登録日2003-12-18
公開日2004-04-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structures of escherichia coli uridine phosphorylase in two native and three complexed forms reveal basis of substrate specificity, induced conformational changes and influence of potassium
J.Mol.Biol., 337, 2004
1RXY
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BU of 1rxy by Molmil
E. coli uridine phosphorylase: type-B native
分子名称: ACETATE ION, GLYCEROL, POTASSIUM ION, ...
著者Caradoc-Davies, T.T, Cutfield, S.M, Lamont, I.L, Cutfield, J.F.
登録日2003-12-18
公開日2004-04-13
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of escherichia coli uridine phosphorylase in two native and three complexed forms reveal basis of substrate specificity, induced conformational changes and influence of potassium
J.Mol.Biol., 337, 2004
1RXU
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BU of 1rxu by Molmil
E. coli uridine phosphorylase: thymidine phosphate complex
分子名称: PHOSPHATE ION, POTASSIUM ION, THYMIDINE, ...
著者Caradoc-Davies, T.T, Cutfield, S.M, Lamont, I.L, Cutfield, J.F.
登録日2003-12-18
公開日2004-04-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Crystal structures of escherichia coli uridine phosphorylase in two native and three complexed forms reveal basis of substrate specificity, induced conformational changes and influence of potassium
J.Mol.Biol., 337, 2004
1RXC
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BU of 1rxc by Molmil
E. COLI uridine phosphorylase: 5-fluorouracil ribose-1-phosphate complex
分子名称: 1-O-phosphono-alpha-D-ribofuranose, 5-FLUOROURACIL, 5-FLUOROURIDINE, ...
著者Caradoc-Davies, T.T, Cutfield, S.M, Lamont, I.L, Cutfield, J.F.
登録日2003-12-18
公開日2004-04-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Crystal structures of escherichia coli uridine phosphorylase in two native and three complexed forms reveal basis of substrate specificity, induced conformational changes and influence of potassium
J.Mol.Biol., 337, 2004
1T0U
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BU of 1t0u by Molmil
Crystal structure of E.coli uridine phosphorylase at 2.2 A resolution (Type-A Native)
分子名称: Uridine phosphorylase
著者Caradoc-Davies, T.T, Cutfield, S.M, Lamont, I.L, Cutfield, J.F.
登録日2004-04-13
公開日2004-04-27
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structures of escherichia coli uridine phosphorylase in two native and three complexed forms reveal basis of substrate specificity, induced conformational changes and influence of potassium
J.Mol.Biol., 337, 2004
4V2T
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BU of 4v2t by Molmil
Membrane embedded pleurotolysin pore with 13 fold symmetry
分子名称: PLEUROTOLYSIN A, PLEUROTOLYSIN B
著者Lukoyanova, N, Kondos, S.C, Farabella, I, Law, R.H.P, Reboul, C.F, Caradoc-Davies, T.T, Spicer, B.A, Kleifeld, O, Perugini, M, Ekkel, S, Hatfaludi, T, Oliver, K, Hotze, E.M, Tweten, R.K, Whisstock, J.C, Topf, M, Dunstone, M.A, Saibil, H.R.
登録日2014-10-15
公開日2015-02-18
最終更新日2017-08-30
実験手法ELECTRON MICROSCOPY (11 Å)
主引用文献Conformational Changes During Pore Formation by the Perforin-Related Protein Pleurotolysin.
Plos Biol., 13, 2015
4OEJ
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BU of 4oej by Molmil
Structure of membrane binding protein pleurotolysin B from Pleurotus ostreatus
分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
著者Dunstone, M.A, Caradoc-Davies, T.T, Whisstock, J.C, Law, R.H.P.
登録日2014-01-13
公開日2015-02-18
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Conformational Changes during Pore Formation by the Perforin-Related Protein Pleurotolysin.
Plos Biol., 13, 2015
6CXO
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BU of 6cxo by Molmil
Complement component-9
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Complement component C9, ...
著者Law, R.H.P, Spicer, B.A, Caradoc-Davies, T.T.
登録日2018-04-03
公開日2018-09-05
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献The first transmembrane region of complement component-9 acts as a brake on its self-assembly.
Nat Commun, 9, 2018
4V3M
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BU of 4v3m by Molmil
Membrane bound pleurotolysin prepore (TMH2 helix lock) trapped with engineered disulphide cross-link
分子名称: PLEUROTOLYSIN A, PLEUROTOLYSIN B
著者Lukoyanova, N, Kondos, S.C, Farabella, I, Law, R.H.P, Reboul, C.F, Caradoc-Davies, T.T, Spicer, B.A, Kleifeld, O, Perugini, M, Ekkel, S, Hatfaludi, T, Oliver, K, Hotze, E.M, Tweten, R.K, Whisstock, J.C, Topf, M, Dunstone, M.A, Saibil, H.R.
登録日2014-10-20
公開日2015-02-18
最終更新日2017-08-23
実験手法ELECTRON MICROSCOPY (17 Å)
主引用文献Conformational Changes During Pore Formation by the Perforin-Related Protein Pleurotolysin.
Plos Biol., 13, 2015
4V3N
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BU of 4v3n by Molmil
Membrane bound pleurotolysin prepore (TMH2 strand lock) trapped with engineered disulphide cross-link
分子名称: PLEUROTOLYSIN A, PLEUROTOLYSIN B
著者Lukoyanova, N, Kondos, S.C, Farabella, I, Law, R.H.P, Reboul, C.F, Caradoc-Davies, T.T, Spicer, B.A, Kleifeld, O, Perugini, M, Ekkel, S, Hatfaludi, T, Oliver, K, Hotze, E.M, Tweten, R.K, Whisstock, J.C, Topf, M, Dunstone, M.A, Saibil, H.R.
登録日2014-10-20
公開日2015-02-18
最終更新日2017-08-23
実験手法ELECTRON MICROSCOPY (14 Å)
主引用文献Conformational Changes During Pore Formation by the Perforin-Related Protein Pleurotolysin.
Plos Biol., 13, 2015
3KLQ
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BU of 3klq by Molmil
Crystal Structure of the Minor Pilin FctB from Streptococcus pyogenes 90/306S
分子名称: GLYCEROL, Putative pilus anchoring protein
著者Linke, C, Young, P.G, Bunker, R.D, Caradoc-Davies, T.T, Baker, E.N.
登録日2009-11-08
公開日2010-04-28
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the minor pilin FctB reveals determinants of Group A streptococcal pilus anchoring
J.Biol.Chem., 285, 2010
2HUO
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BU of 2huo by Molmil
Crystal structure of mouse myo-inositol oxygenase in complex with substrate
分子名称: 1,2,3,4,5,6-HEXAHYDROXY-CYCLOHEXANE, FE (III) ION, FORMIC ACID, ...
著者Brown, P.M, Caradoc-Davies, T.T, Dickson, J.M.J, Cooper, G.J.S, Loomes, K.M, Baker, E.N.
登録日2006-07-27
公開日2006-09-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a substrate complex of myo-inositol oxygenase, a di-iron oxygenase with a key role in inositol metabolism.
Proc.Natl.Acad.Sci.Usa, 103, 2006
6DN7
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BU of 6dn7 by Molmil
SPRY domain-containing SOCS box protein 2 complexed with WDINNN(BAL) Cyclic peptide inhibitor
分子名称: CHLORIDE ION, SPRY domain-containing SOCS box protein 4, WDINNN(BAL) Cyclic peptide inhibitor
著者Law, R.H.P, Caradoc-Davies, T.T, Norton, R.S.
登録日2018-06-06
公開日2019-04-17
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent.
ACS Chem. Biol., 13, 2018
5ULM
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BU of 5ulm by Molmil
Structure of the ASK1 central regulatory region
分子名称: GLYCEROL, Mitogen-activated protein kinase kinase kinase 5
著者Mace, P.D, Kumar, A, Caradoc-Davies, T.T.
登録日2017-01-24
公開日2017-03-01
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of autoregulatory scaffolding by apoptosis signal-regulating kinase 1.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6DN6
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BU of 6dn6 by Molmil
SPRY domain-containing SOCS box protein 2 complexed with INNN(ABU) cyclic peptide inhibitor
分子名称: INNN(ABU) cyclic peptide inhibitor, SPRY domain-containing SOCS box protein 2
著者Law, R.H.P, Caradoc-Davies, T.T, Norton, R.S.
登録日2018-06-06
公開日2019-04-17
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent.
ACS Chem. Biol., 13, 2018
6DN8
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BU of 6dn8 by Molmil
SPRY domain-containing SOCS box protein 2 complexed with (GZJ)VDINNN(CY3) Cyclic peptide inhibitor
分子名称: (GZJ)VDINNN(CY3) Cyclic peptide inhibitor, ACETATE ION, SPRY domain-containing SOCS box protein 4, ...
著者Law, R.H.P, Caradoc-Davies, T.T, Norton, R.S.
登録日2018-06-06
公開日2019-04-17
最終更新日2022-04-13
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent.
ACS Chem. Biol., 13, 2018
6DN5
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BU of 6dn5 by Molmil
SPRY domain-containing SOCS box protein 2 complexed with WDINNN(BAL) cyclic peptide inhibitor
分子名称: SPRY domain-containing SOCS box protein 2, SULFATE ION, WDINNN(BAL) cyclic peptide inhibitor
著者Law, R.H.P, Caradoc-Davies, T.T, Norton, R.S.
登録日2018-06-06
公開日2019-04-17
最終更新日2020-01-08
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献A Cyclic Peptide Inhibitor of the iNOS-SPSB Protein-Protein Interaction as a Potential Anti-Infective Agent.
ACS Chem. Biol., 13, 2018
3NSJ
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BU of 3nsj by Molmil
The X-ray crystal structure of lymphocyte perforin
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CHLORIDE ION, ...
著者Law, R.H, Whisstock, J.C, Caradoc-Davies, T.T.
登録日2010-07-01
公開日2010-11-03
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献The structural basis for membrane binding and pore formation by lymphocyte perforin.
Nature, 468, 2010
3OVU
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BU of 3ovu by Molmil
Crystal Structure of Human Alpha-Haemoglobin Complexed with AHSP and the First NEAT Domain of IsdH from Staphylococcus aureus
分子名称: Alpha-hemoglobin-stabilizing protein, Hemoglobin subunit alpha, Iron-regulated surface determinant protein H, ...
著者Jacques, D.A, Krishna Kumar, K, Caradoc-Davies, T.T, Langley, D.B, Mackay, J.P, Guss, J.M, Gell, D.A.
登録日2010-09-17
公開日2011-09-21
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献A new haem pocket structure in alpha-haemoglobin
To be Published
3GI1
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BU of 3gi1 by Molmil
Crystal Structure of the laminin-binding protein Lbp of Streptococcus pyogenes
分子名称: Laminin-binding protein of group A streptococci, ZINC ION
著者Linke, C, Caradoc-Davies, T.T, Young, P.G, Proft, T, Baker, E.N.
登録日2009-03-04
公開日2009-08-04
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献The laminin-binding protein Lbp from Streptococcus pyogenes is a zinc receptor
J.Bacteriol., 191, 2009
4OEB
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BU of 4oeb by Molmil
Structure of membrane binding protein pleurotolysin A from Pleurotus ostreatus
分子名称: Pleurotolysin A, SULFATE ION
著者Dunstone, M.A, Caradoc-Davies, T.T, Whisstock, J.C, Law, R.H.P.
登録日2014-01-12
公開日2015-02-18
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Conformational Changes during Pore Formation by the Perforin-Related Protein Pleurotolysin.
Plos Biol., 13, 2015
6OG4
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BU of 6og4 by Molmil
plasminogen binding group A streptococcal M protein
分子名称: Plasminogen, Plasminogen-binding group A streptococcal M-like protein PAM, SULFATE ION
著者Law, R.H.P, Quek, A.J, Whisstock, J.C, Caradoc-Davies, T.T.
登録日2019-04-01
公開日2019-07-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structure and Function Characterization of the a1a2 Motifs of Streptococcus pyogenes M Protein in Human Plasminogen Binding.
J.Mol.Biol., 431, 2019
4P48
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BU of 4p48 by Molmil
The structure of a chicken anti-cardiac Troponin I scFv
分子名称: Antibody scFv 180
著者Conroy, P.J, Law, R.H.P, Gillgunn, S, Hearty, S, Caradoc-Davies, T.T, Llyod, G, O'Kennedy, R.J, Whisstock, J.C.
登録日2014-03-12
公開日2014-04-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Reconciling the structural attributes of avian antibodies.
J.Biol.Chem., 289, 2014
4P49
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BU of 4p49 by Molmil
The structure of a chicken anti-prostate specific antigen scFv
分子名称: ACETATE ION, Antibody scFv B8, SULFATE ION
著者Conroy, P.J, Law, R.H.P, Gilgunn, S, Hearty, S, Llyod, G, Caradoc-Davies, T.T, O'Kennedy, R.J, Whisstock, J.C.
登録日2014-03-12
公開日2014-04-23
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Reconciling the structural attributes of avian antibodies.
J.Biol.Chem., 289, 2014
6MQV
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BU of 6mqv by Molmil
Structure of HEWL from LCP injector using synchrotron radiation
分子名称: Lysozyme C, SODIUM ION
著者Caradoc-Davies, T.T, Aishima, J, Berntsen, P, Hadian-Jazi, M.
登録日2018-10-10
公開日2019-09-11
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The serial millisecond crystallography instrument at the Australian Synchrotron incorporating the "Lipidico" injector.
Rev Sci Instrum, 90, 2019

 

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