6HBS
 
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6HBV
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4TQX
 | | Molecular Basis of Streptococcus mutans Sortase A Inhibition by Chalcone. | | 分子名称: | ACETIC ACID, SULFATE ION, Sortase, ... | | 著者 | Wallock-Richards, D.J, Marles-Wright, J, Clarke, D.J, Maitra, A, Dodds, M, Hanley, B, Campopiano, D.J. | | 登録日 | 2014-06-12 | | 公開日 | 2015-05-20 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | | 主引用文献 | Molecular basis of Streptococcus mutans sortase A inhibition by the flavonoid natural product trans-chalcone.
Chem.Commun.(Camb.), 51, 2015
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1BS0
 | | PLP-DEPENDENT ACYL-COA SYNTHASE | | 分子名称: | PROTEIN (8-AMINO-7-OXONANOATE SYNTHASE), SULFATE ION | | 著者 | Alexeev, D, Alexeeva, M, Baxter, R.L, Campopiano, D.J, Webster, S.P, Sawyer, L. | | 登録日 | 1998-08-31 | | 公開日 | 1999-08-27 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | The crystal structure of 8-amino-7-oxononanoate synthase: a bacterial PLP-dependent, acyl-CoA-condensing enzyme.
J.Mol.Biol., 284, 1998
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1XC1
 | | Oxo Zirconium(IV) Cluster in the Ferric Binding Protein (FBP) | | 分子名称: | OXO ZIRCONIUM(IV) CLUSTER, periplasmic iron-binding protein | | 著者 | Zhong, W, Alexeev, D, Harvey, I, Guo, M, Hunter, D.J.B, Zhu, H, Campopiano, D.J, Sadler, P.J. | | 登録日 | 2004-08-31 | | 公開日 | 2004-09-21 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | Assembly of an Oxo-Zirconium(IV) Cluster in a Protein Cleft
Angew.Chem.Int.Ed.Engl., 43, 2004
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5K1R
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5G1F
 | | Crystal structure of the 6-carboxyhexanoate-CoA ligase (BioW)from Bacillus subtilis in complex with coenzyme A | | 分子名称: | 6-CARBOXYHEXANOATE-COA LIGASE, COENZYME A, NONAETHYLENE GLYCOL, ... | | 著者 | Moynie, L, Wang, M, Campopiano, D.J, Naismith, J.H. | | 登録日 | 2016-03-25 | | 公開日 | 2017-03-08 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | | 主引用文献 | The Structure of the 6-Carboxyhexanoate-Coa Ligase from Bacillus Subtilis
To be Published
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1R1N
 | | Tri-nuclear oxo-iron clusters in the ferric binding protein from N. gonorrhoeae | | 分子名称: | Ferric-iron Binding Protein, OXO-IRON CLUSTER 1, OXO-IRON CLUSTER 2, ... | | 著者 | Zhu, H, Alexeev, D, Hunter, D.J, Campopiano, D.J, Sadler, P.J. | | 登録日 | 2003-09-24 | | 公開日 | 2004-03-09 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.74 Å) | | 主引用文献 | Oxo-iron clusters in a bacterial iron-trafficking protein: new roles for a conserved motif.
Biochem.J., 376, 2003
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3EFR
 | | Biotin protein ligase R40G mutant from Aquifex aeolicus in complex with biotin | | 分子名称: | BIOTIN, Biotin [acetyl-CoA-carboxylase] ligase, SULFATE ION | | 著者 | Tron, C.M, McNae, I.W, Walkinshaw, M.D, Baxter, R.L, Campopiano, D.J. | | 登録日 | 2008-09-10 | | 公開日 | 2009-06-09 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | Structural and functional studies of the biotin protein ligase from Aquifex aeolicus reveal a critical role for a conserved residue in target specificity.
J.Mol.Biol., 387, 2009
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3EFS
 | | Biotin protein ligase from Aquifex aeolicus in complex with biotin and ATP | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, BIOTIN, Biotin [acetyl-CoA-carboxylase] ligase, ... | | 著者 | Tron, C.M, McNae, I.W, Walkinshaw, M.D, Baxter, R.L, Campopiano, D.J. | | 登録日 | 2008-09-10 | | 公開日 | 2009-06-09 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural and functional studies of the biotin protein ligase from Aquifex aeolicus reveal a critical role for a conserved residue in target specificity.
J.Mol.Biol., 387, 2009
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3FJP
 | | Apo structure of Biotin protein ligase from Aquifex aeolicus | | 分子名称: | Biotin [acetyl-CoA-carboxylase] ligase, SULFATE ION | | 著者 | McNae, I.W, Tron, C.M, Baxter, R.L, Walkinshaw, M.D, Campopiano, D.J. | | 登録日 | 2008-12-15 | | 公開日 | 2009-06-09 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural and functional studies of the biotin protein ligase from Aquifex aeolicus reveal a critical role for a conserved residue in target specificity.
J.Mol.Biol., 387, 2009
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1O7T
 | | Metal nanoclusters bound to the Ferric Binding Protein from Neisseria gonorrhoeae. | | 分子名称: | HF OXO CLUSTER HF5, HF-OXO-PHOSPHATE CLUSTER PHF, IRON BINDING PROTEIN, ... | | 著者 | Alexeev, D, Zu, H, Guo, M, Zhong, W, Hunter, D.J.B, Yang, W, Campopiano, D.J, Sadler, P.J. | | 登録日 | 2002-11-12 | | 公開日 | 2003-02-27 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | A novel protein-mineral interface.
Nat. Struct. Biol., 10, 2003
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4BMK
 | | Serine Palmitoyltransferase K265A from S. paucimobilis with bound PLP- Myriocin Aldimine | | 分子名称: | Decarboxylated Myriocin, GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, ... | | 著者 | Wadsworth, J.M, Clarke, D.J, McMahon, S.A, Beattie, A.E, Lowther, J, Dunn, T.M, Naismith, J.H, Campopiano, D.J. | | 登録日 | 2013-05-09 | | 公開日 | 2013-09-04 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | | 主引用文献 | The Chemical Basis of Serine Palmitoyltransferase Inhibition by Myriocin.
J.Am.Chem.Soc., 135, 2013
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2XBN
 | | Inhibition of the PLP-dependent enzyme serine palmitoyltransferase by cycloserine: evidence for a novel decarboxylative mechanism of inactivation | | 分子名称: | 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, MAGNESIUM ION, SERINE PALMITOYLTRANSFERASE | | 著者 | Lowther, J, Yard, B.A, Johnson, K.A, Carter, L.G, Bhat, V.T, Raman, M.C.C, Clarke, D.J, Ramakers, B, McMahon, S.A, Naismith, J.H, Campopiano, D.J. | | 登録日 | 2010-04-13 | | 公開日 | 2010-05-19 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Inhibition of the Plp-Dependent Enzyme Serine Palmitoyltransferase by Cycloserine: Evidence for a Novel Decarboxylative Mechanism of Inactivation.
Mol.Biosystems, 6, 2010
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2X8U
 | | Sphingomonas wittichii Serine palmitoyltransferase | | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, SERINE PALMITOYLTRANSFERASE | | 著者 | Raman, M.C.C, Johnson, K.A, Campopiano, D.J, Naismith, J.H. | | 登録日 | 2010-03-12 | | 公開日 | 2010-03-23 | | 最終更新日 | 2015-11-11 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The Serine Palmitoyltransferase from Sphingomonas Wittichii Rw1 an Interesting Link to an Unusual Acyl Carrier Protein
Biopolymers, 93, 2010
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4A6G
 | | N-acyl amino acid racemase from Amycalotopsis sp. Ts-1-60: G291D- F323Y mutant in complex with N-acetyl methionine | | 分子名称: | MAGNESIUM ION, N-ACETYLMETHIONINE, N-ACYLAMINO ACID RACEMASE | | 著者 | Baxter, S, Royer, S, Grogan, G, Holt-Tiffin, K.E, Taylor, I.N, Fotheringham, I.G, Campopiano, D.J. | | 登録日 | 2011-11-02 | | 公開日 | 2012-11-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.71 Å) | | 主引用文献 | An Improved Racemase/Acylase Biotransformation for the Preparation of Enantiomerically Pure Amino Acids.
J.Am.Chem.Soc., 134, 2012
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1DJE
 | | CRYSTAL STRUCTURE OF THE PLP-BOUND FORM OF 8-AMINO-7-OXONANOATE SYNTHASE | | 分子名称: | 8-AMINO-7-OXONANOATE SYNTHASE, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION | | 著者 | Webster, S.P, Alexeev, D, Campopiano, D.J, Watt, R.M, Alexeeva, M, Sawyer, L, Baxter, R.L. | | 登録日 | 1999-12-02 | | 公開日 | 2000-12-04 | | 最終更新日 | 2018-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.71 Å) | | 主引用文献 | Mechanism of 8-amino-7-oxononanoate synthase: spectroscopic, kinetic, and crystallographic studies.
Biochemistry, 39, 2000
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1DJ9
 | | CRYSTAL STRUCTURE OF 8-AMINO-7-OXONANOATE SYNTHASE (OR 7-KETO-8AMINIPELARGONATE OR KAPA SYNTHASE) COMPLEXED WITH PLP AND THE PRODUCT 8(S)-AMINO-7-OXONANONOATE (OR KAPA). THE ENZYME OF BIOTIN BIOSYNTHETIC PATHWAY. | | 分子名称: | 8-AMINO-7-OXONONANOATE SYNTHASE, MAGNESIUM ION, N-[7-KETO-8-AMINOPELARGONIC ACID]-[3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YL-METHANE], ... | | 著者 | Webster, S.P, Alexeev, D, Campopiano, D.J, Watt, R.M, Alexeeva, M, Sawyer, L, Baxter, R.L. | | 登録日 | 1999-12-02 | | 公開日 | 2000-12-06 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Mechanism of 8-amino-7-oxononanoate synthase: spectroscopic, kinetic, and crystallographic studies.
Biochemistry, 39, 2000
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6G1F
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5DBV
 | | Structure of a C269A mutant of propionaldehyde dehydrogenase from the Clostridium phytofermentans fucose utilisation bacterial microcompartment | | 分子名称: | ACETATE ION, Aldehyde Dehydrogenase, COENZYME A, ... | | 著者 | Tuck, L.R, Altenbach, K, Ang, T.F, Crawshaw, A.D, Campopiano, D.J, Clarke, D.J, Marles-Wright, J. | | 登録日 | 2015-08-22 | | 公開日 | 2016-03-16 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | | 主引用文献 | Insight into Coenzyme A cofactor binding and the mechanism of acyl-transfer in an acylating aldehyde dehydrogenase from Clostridium phytofermentans.
Sci Rep, 6, 2016
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5DRU
 | | Structure of His387Ala mutant of the propionaldehyde dehydrogenase from the Clostridium phytofermentans fucose utilisation bacterial microcompartment | | 分子名称: | Aldehyde Dehydrogenase, SULFATE ION | | 著者 | Tuck, L.R, Altenbach, K, Fu, A.T, Crawshaw, A.D, Campopiano, D.J, Clarke, D.J, Marles-Wright, J. | | 登録日 | 2015-09-16 | | 公開日 | 2016-03-16 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.083 Å) | | 主引用文献 | Insight into Coenzyme A cofactor binding and the mechanism of acyl-transfer in an acylating aldehyde dehydrogenase from Clostridium phytofermentans.
Sci Rep, 6, 2016
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2JG2
 | | HIGH RESOLUTION STRUCTURE OF SPT WITH PLP INTERNAL ALDIMINE | | 分子名称: | MAGNESIUM ION, PYRIDOXAL-5'-PHOSPHATE, SERINE PALMITOYLTRANSFERASE | | 著者 | Yard, B.A, Carter, L.G, Johnson, K.A, Overton, I.M, Mcmahon, S.A, Dorward, M, Liu, H, Puech, D, Oke, M, Barton, G.J, Naismith, J.H, Campopiano, D.J. | | 登録日 | 2007-02-07 | | 公開日 | 2007-05-01 | | 最終更新日 | 2015-11-11 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | The Structure of Serine Palmitoyltransferase; Gateway to Sphingolipid Biosynthesis.
J.Mol.Biol., 370, 2007
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2JGT
 | | Low resolution structure of SPT | | 分子名称: | SERINE PALMITOYLTRANSFERASE | | 著者 | Yard, B.A, Carter, L.G, Johnson, K.A, Overton, I.M, Mcmahon, S.A, Dorward, M, Liu, H, Puech, D, Oke, M, Barton, G.J, Naismith, J.H, Campopiano, D.J. | | 登録日 | 2007-02-14 | | 公開日 | 2007-05-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | The Structure of Serine Palmitoyltransferase; Gateway to Sphingolipid Biosynthesis.
J.Mol.Biol., 370, 2007
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2W8V
 | | SPT with PLP, N100W | | 分子名称: | PYRIDOXAL-5'-PHOSPHATE, SERINE PALMITOYLTRANSFERASE | | 著者 | Raman, M.C.C, Johnson, K.A, Campopiano, D.J, Naismith, J.H. | | 登録日 | 2009-01-19 | | 公開日 | 2009-01-27 | | 最終更新日 | 2015-11-18 | | 実験手法 | X-RAY DIFFRACTION (1.43 Å) | | 主引用文献 | The External-Aldimine Form of Serine Palmitoyltranserase; Structural, Kinetic and Spectroscopic Analysis of the Wild-Type Enzyme and Hsan1 Mutant Mimics.
J.Biol.Chem., 284, 2009
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2W8J
 | | SPT with PLP-ser | | 分子名称: | SERINE PALMITOYLTRANSFERASE, [3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL]-SERINE | | 著者 | Carter, L.G, Raman, M.C.C, Johnson, K.A, Campopiano, D.J, Naismith, J.H. | | 登録日 | 2009-01-16 | | 公開日 | 2009-01-27 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The External-Aldimine Form of Serine Palmitoyltranserase; Structural, Kinetic and Spectroscopic Analysis of the Wild-Type Enzyme and Hsan1 Mutant Mimics.
J.Biol.Chem., 284, 2009
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