7QVV
| BAZ2A bromodomain in complex with pyridone derivative fragment 36 | Descriptor: | 5-(4-azanylpiperidin-1-yl)carbonyl-1~{H}-pyridin-2-one, Bromodomain adjacent to zinc finger domain protein 2A | Authors: | Dalle Vedove, A, Cazzanelli, G, Caflisch, A, Lolli, G. | Deposit date: | 2022-01-23 | Release date: | 2022-09-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.601 Å) | Cite: | Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing. Acs Med.Chem.Lett., 13, 2022
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7QYU
| BAZ2A bromodomain in complex with acetylpyrrole derivative compound 88 | Descriptor: | 2-[4-[[4-[4-(4-ethanoyl-3-ethyl-5-methyl-1~{H}-pyrrol-2-yl)-1,3-thiazol-2-yl]piperazin-1-yl]methyl]-1,2,3-triazol-1-yl]ethanamide, Bromodomain adjacent to zinc finger domain protein 2A | Authors: | Dalle Vedove, A, Cazzanelli, G, Caflisch, A, Lolli, G. | Deposit date: | 2022-01-29 | Release date: | 2022-09-28 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Identification of a BAZ2A-Bromodomain Hit Compound by Fragment Growing. Acs Med.Chem.Lett., 13, 2022
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8Q33
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8Q4R
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8Q2W
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8Q2X
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8Q4W
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8Q3A
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8Q4V
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8Q2T
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8Q2U
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8Q37
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8Q2V
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8Q2Y
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8Q3G
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8Q4M
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8Q4P
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8Q38
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8Q4T
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8Q2R
| Crystal structure of YTHDC1 in complex with Compound 3 (ZA_431) | Descriptor: | 5-chloranyl-~{N},3-dimethyl-1~{H}-pyrazolo[4,3-d]pyrimidin-7-amine, SULFATE ION, YTH domain-containing protein 1 | Authors: | Bedi, R.K, Zalesak, F, Li, Y, Caflisch, A. | Deposit date: | 2023-08-03 | Release date: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Crystal structure of YTHDC1 in complex with Compound 3 (ZA_431) To Be Published
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8Q2S
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8Q31
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8Q35
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8Q39
| Crystal structure of YTHDC1 in complex with Compound 21 (ZA_515) | Descriptor: | 2-chloranyl-N-methyl-9-[[3-(1H-1,2,3,4-tetrazol-5-yl)phenyl]methyl]purin-6-amine, SULFATE ION, YTH domain-containing protein 1 | Authors: | Bedi, R.K, Zalesak, F, Caflisch, A. | Deposit date: | 2023-08-03 | Release date: | 2023-12-06 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Crystal structure of YTHDC1 in complex with Compound 21 (ZA_515) To Be Published
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8Q4U
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