1E3K
| Human Progesteron Receptor Ligand Binding Domain in complex with the ligand metribolone (R1881) | Descriptor: | (17BETA)-17-HYDROXY-17-METHYLESTRA-4,9,11-TRIEN-3-ONE, PROGESTERONE RECEPTOR | Authors: | Matias, P.M, Donner, P, Coelho, R, Thomaz, M, Peixoto, C, Macedo, S, Otto, N, Joschko, S, Scholz, P, Wegg, A, Basler, S, Schafer, M, Egner, U, Carrondo, M.A. | Deposit date: | 2000-06-19 | Release date: | 2001-06-14 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural evidence for ligand specificity in the binding domain of the human androgen receptor. Implications for pathogenic gene mutations. J. Biol. Chem., 275, 2000
|
|
1DRF
| |
1DSL
| GAMMA B CRYSTALLIN C-TERMINAL DOMAIN | Descriptor: | GAMMA B CRYSTALLIN | Authors: | Norledge, B.V, Mayr, E.-M, Glockshuber, R, Bateman, O.A, Slingsby, C, Jaenicke, R, Driessen, H.P.C. | Deposit date: | 1996-02-01 | Release date: | 1996-07-11 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | The X-ray structures of two mutant crystallin domains shed light on the evolution of multi-domain proteins. Nat.Struct.Biol., 3, 1996
|
|
1DOX
| 1H AND 15N SEQUENTIAL ASSIGNMENT, SECONDARY STRUCTURE AND TERTIARY FOLD OF [2FE-2S] FERREDOXIN FROM SYNECHOCYSTIS SP. PCC 6803 | Descriptor: | FE2/S2 (INORGANIC) CLUSTER, FERREDOXIN [2FE-2S] | Authors: | Lelong, C, Setif, P, Bottin, H, Andre, F, Neumann, J.M. | Deposit date: | 1995-09-14 | Release date: | 1996-03-08 | Last modified: | 2024-04-10 | Method: | SOLUTION NMR | Cite: | 1H and 15N NMR sequential assignment, secondary structure, and tertiary fold of [2Fe-2S] ferredoxin from Synechocystis sp. PCC 6803. Biochemistry, 34, 1995
|
|
1E0L
| |
1E0M
| |
1DZD
| High resolution structure of acidic fibroblast growth factor (27-154), 24 NMR structures | Descriptor: | ACIDIC FIBROBLAST GROWTH FACTOR | Authors: | Lozano, R.M, Pineda-Lucena, A, Gonzalez, C, Jimenez, M.A, Cuevas, P, Redondo-Horcajo, M, Sanz, J.M, Rico, M, Gimenez-Gallego, G. | Deposit date: | 2000-02-24 | Release date: | 2000-03-16 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | 1H-NMR Structural Characterization of a Non Mitogenic, Vasodilatory, Ischemia-Protector and Neuromodulatory Acidic Fibroblast Growth Factor Biochemistry, 39, 2000
|
|
1ECU
| SOLUTION STRUCTURE OF E2F BINDING DNA FRAGMENT GCGCGAAAC-T-GTTTCGCGC | Descriptor: | DNA (5'-D(*GP*CP*GP*CP*GP*AP*AP*AP*CP*TP*GP*TP*TP*TP*CP*GP*CP*GP*C)-3') | Authors: | Wu, J.H, Chang, C, Pei, J.M, Xiao, Q, Shi, Y.Y. | Deposit date: | 2000-01-26 | Release date: | 2000-02-02 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | Solution structure of E2F binding DNA fragment GCGCGAAAC-T-GTTTCGCGC studied by Molecular Dynamics Simulation and Two Dimensional NMR experiment to be published, 2000
|
|
1EI9
| CRYSTAL STRUCTURE OF PALMITOYL PROTEIN THIOESTERASE 1 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, PALMITOYL PROTEIN THIOESTERASE 1 | Authors: | Bellizzi III, J.J, Widom, J, Kemp, C, Lu, J.Y, Das, A.K, Hofmann, S.L, Clardy, J. | Deposit date: | 2000-02-24 | Release date: | 2000-04-26 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | The crystal structure of palmitoyl protein thioesterase 1 and the molecular basis of infantile neuronal ceroid lipofuscinosis. Proc.Natl.Acad.Sci.USA, 97, 2000
|
|
1EMV
| CRYSTAL STRUCTURE OF COLICIN E9 DNASE DOMAIN WITH ITS COGNATE IMMUNITY PROTEIN IM9 (1.7 ANGSTROMS) | Descriptor: | COLICIN E9, IMMUNITY PROTEIN IM9, PHOSPHATE ION | Authors: | Kuhlmann, U.C, Pommer, A.J, Moore, G.M, James, R, Kleanthous, C. | Deposit date: | 2000-03-20 | Release date: | 2000-09-13 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Specificity in protein-protein interactions: the structural basis for dual recognition in endonuclease colicin-immunity protein complexes. J.Mol.Biol., 301, 2000
|
|
1E7Q
| GDP 4-keto-6-deoxy-D-mannose epimerase reductase S107A | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETYLPHOSPHATE, GDP-FUCOSE SYNTHETASE, ... | Authors: | Rosano, C, Izzo, G, Bolognesi, M. | Deposit date: | 2000-09-07 | Release date: | 2000-10-18 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Probing the Catalytic Mechanism of Gdp-4-Keto-6-Deoxy-D-Mannose Epimerase/Reductase by Kinetic and Crystallographic Characterization of Site-Specific Mutants J.Mol.Biol., 303, 2000
|
|
1E5P
| Crystal structure of aphrodisin, a sex pheromone from female hamster | Descriptor: | APHRODISIN | Authors: | Vincent, F, Brown, K, Spinelli, S, Cambillau, C, Tegoni, M. | Deposit date: | 2000-07-28 | Release date: | 2001-07-26 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.63 Å) | Cite: | Crystal structure of aphrodisin, a sex pheromone from female hamster. J.Mol.Biol., 305, 2001
|
|
1EAQ
| The RUNX1 Runt domain at 1.25A resolution: A structural switch and specifically bound chloride ions modulate DNA binding | Descriptor: | CHLORIDE ION, RUNT-RELATED TRANSCRIPTION FACTOR 1 | Authors: | Backstrom, S, Wolf-Watz, M, Grundstrom, C, Hard, T, Grundstrom, T, Sauer, U.H. | Deposit date: | 2001-07-14 | Release date: | 2002-09-12 | Method: | X-RAY DIFFRACTION (1.25 Å) | Cite: | The Runx1 Runt Domain at 1.25 A Resolution: A Structural Switch and Specifically Bound Chloride Ions Modulate DNA Binding J.Mol.Biol., 322, 2002
|
|
1EER
| |
1ESO
| MONOMERIC CU,ZN SUPEROXIDE DISMUTASE FROM ESCHERICHIA COLI | Descriptor: | COPPER (II) ION, CU, ZN SUPEROXIDE DISMUTASE, ... | Authors: | Pesce, A, Capasso, C, Battistoni, A, Folcarelli, S, Rotilio, G, Desideri, A, Bolognesi, M. | Deposit date: | 1997-06-27 | Release date: | 1998-07-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Unique structural features of the monomeric Cu,Zn superoxide dismutase from Escherichia coli, revealed by X-ray crystallography. J.Mol.Biol., 274, 1997
|
|
1EWR
| CRYSTAL STRUCTURE OF TAQ MUTS | Descriptor: | DNA MISMATCH REPAIR PROTEIN MUTS | Authors: | Obmolova, G, Ban, C, Hsieh, P, Yang, W. | Deposit date: | 2000-04-26 | Release date: | 2000-10-23 | Last modified: | 2018-06-27 | Method: | X-RAY DIFFRACTION (3.19 Å) | Cite: | Crystal structures of mismatch repair protein MutS and its complex with a substrate DNA. Nature, 407, 2000
|
|
1ELQ
| CRYSTAL STRUCTURE OF THE CYSTINE C-S LYASE C-DES | Descriptor: | L-CYSTEINE/L-CYSTINE C-S LYASE, POTASSIUM ION, PYRIDOXAL-5'-PHOSPHATE | Authors: | Clausen, T, Kaiser, J.T, Steegborn, C, Huber, R, Kessler, D. | Deposit date: | 2000-03-14 | Release date: | 2000-04-19 | Last modified: | 2021-11-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of the cystine C-S lyase from Synechocystis: stabilization of cysteine persulfide for FeS cluster biosynthesis. Proc.Natl.Acad.Sci.USA, 97, 2000
|
|
1EO0
| CONSERVED DOMAIN COMMON TO TRANSCRIPTION FACTORS TFIIS, ELONGIN A, CRSP70 | Descriptor: | TRANSCRIPTION ELONGATION FACTOR S-II | Authors: | Booth, V, Koth, C, Edwards, A.M, Arrowsmith, C.H, Northeast Structural Genomics Consortium (NESG) | Deposit date: | 2000-03-21 | Release date: | 2000-05-03 | Last modified: | 2022-02-16 | Method: | SOLUTION NMR | Cite: | Structure of a conserved domain common to the transcription factors TFIIS, elongin A, and CRSP70 J.Biol.Chem., 275, 2000
|
|
1E68
| Solution structure of bacteriocin AS-48 | Descriptor: | AS-48 PROTEIN | Authors: | Gonzalez, C, Langdon, G, Bruix, M, Galvez, A, Valdivia, E, Maqueda, M, Rico, M. | Deposit date: | 2000-08-09 | Release date: | 2000-10-25 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Bacteriocin as-48, a Microbial Cyclic Polypeptide Structurally and Functionally Related to Mammalian Nk-Lysin Proc.Natl.Acad.Sci.USA, 97, 2000
|
|
1EFW
| Crystal structure of aspartyl-tRNA synthetase from Thermus thermophilus complexed to tRNAasp from Escherichia coli | Descriptor: | ASPARTYL-TRNA, ASPARTYL-TRNA SYNTHETASE | Authors: | Briand, C, Poterszman, A, Eiler, S, Webster, G, Thierry, J.-C, Moras, D. | Deposit date: | 2000-02-10 | Release date: | 2000-06-19 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | An intermediate step in the recognition of tRNA(Asp) by aspartyl-tRNA synthetase. J.Mol.Biol., 299, 2000
|
|
1E7N
| The N-terminal domain of beta-B2-crystallin resembles the putative ancestral homodimer | Descriptor: | BETA-CRYSTALLIN B2 | Authors: | Clout, N.J, Basak, A, Wieligmann, K, Bateman, O.A, Jaenicke, R, Slingsby, C. | Deposit date: | 2000-08-31 | Release date: | 2000-10-05 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | The N-Terminal Domain of Betab2-Crystallin Resembles the Putative Ancestral Homodimer. J.Mol.Biol., 304, 2000
|
|
1ELR
| Crystal structure of the TPR2A domain of HOP in complex with the HSP90 peptide MEEVD | Descriptor: | HSP90-PEPTIDE MEEVD, NICKEL (II) ION, TPR2A-DOMAIN OF HOP | Authors: | Scheufler, C, Brinker, A, Hartl, F.U, Moarefi, I. | Deposit date: | 2000-03-14 | Release date: | 2000-04-26 | Last modified: | 2017-10-04 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Structure of TPR domain-peptide complexes: critical elements in the assembly of the Hsp70-Hsp90 multichaperone machine. Cell(Cambridge,Mass.), 101, 2000
|
|
1ELZ
| E. COLI ALKALINE PHOSPHATASE MUTANT (S102G) | Descriptor: | ALKALINE PHOSPHATASE, MAGNESIUM ION, PHOSPHATE ION, ... | Authors: | Stec, B, Hehir, M, Brennan, C, Nolte, M, Kantrowitz, E.R. | Deposit date: | 1998-02-10 | Release date: | 1998-05-27 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Kinetic and X-ray structural studies of three mutant E. coli alkaline phosphatases: insights into the catalytic mechanism without the nucleophile Ser102. J.Mol.Biol., 277, 1998
|
|
1EP4
| Crystal structure of HIV-1 reverse transcriptase in complex with S-1153 | Descriptor: | 5-(3,5-DICHLOROPHENYL)THIO-4-ISOPROPYL-1-(PYRIDIN-4-YL-METHYL)-1H-IMIDAZOL-2-YL-METHYL CARBAMATE, HIV-1 REVERSE TRANSCRIPTASE | Authors: | Ren, J, Nichols, C, Bird, L.E, Fujiwara, T, Suginoto, H, Stuart, D.I, Stammers, D.K. | Deposit date: | 2000-03-27 | Release date: | 2000-09-27 | Last modified: | 2014-11-12 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Binding of the second generation non-nucleoside inhibitor S-1153 to HIV-1 reverse transcriptase involves extensive main chain hydrogen bonding. J.Biol.Chem., 275, 2000
|
|
1EET
| HIV-1 REVERSE TRANSCRIPTASE IN COMPLEX WITH THE INHIBITOR MSC204 | Descriptor: | 1-(5-BROMO-PYRIDIN-2-YL)-3-[2-(6-FLUORO-2-HYDROXY-3-PROPIONYL-PHENYL)-CYCLOPROPYL]-UREA, HIV-1 REVERSE TRANSCRIPTASE | Authors: | Hogberg, M, Sahlberg, C, Engelhardt, P, Noreen, R, Kangasmetsa, J, Johansson, N.G, Oberg, B, Vrang, L, Zhang, H, Sahlberg, B.L, Unge, T, Lovgren, S, Fridborg, K, Backbro, K. | Deposit date: | 2000-02-03 | Release date: | 2001-02-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.73 Å) | Cite: | Urea-PETT compounds as a new class of HIV-1 reverse transcriptase inhibitors. 3. Synthesis and further structure-activity relationship studies of PETT analogues. J.Med.Chem., 42, 1999
|
|