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6DU3
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BU of 6du3 by Molmil
Structure of Scp1 D96N bound to REST-pS861/4 peptide
Descriptor: Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1, MAGNESIUM ION, REST-pS861
Authors:Burkholder, N.T, Mayfield, J.E, Yu, X, Irani, S, Arce, D.K, Jiang, F, Matthews, W, Xue, Y, Zhang, Y.J.
Deposit date:2018-06-19
Release date:2018-09-26
Last modified:2020-01-01
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST).
J. Biol. Chem., 293, 2018
6DU2
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BU of 6du2 by Molmil
Structure of Scp1 D96N bound to REST-pS861/4 peptide
Descriptor: MAGNESIUM ION, REST-pS861/4, carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform X2
Authors:Burkholder, N.T, Mayfield, J.E, Yu, X, Irani, S, Arce, D.K, Jiang, F, Matthews, W, Xue, Y, Zhang, Y.J.
Deposit date:2018-06-19
Release date:2018-09-26
Last modified:2024-10-16
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Phosphatase activity of small C-terminal domain phosphatase 1 (SCP1) controls the stability of the key neuronal regulator RE1-silencing transcription factor (REST).
J. Biol. Chem., 293, 2018
7S3V
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BU of 7s3v by Molmil
Structure of HsKYNase_66, an evolved variant of human kynureninase with greatly increased activity towards kynurenine
Descriptor: Kynureninase
Authors:Burkholder, N.T, Zhang, Y.J.
Deposit date:2021-09-08
Release date:2022-12-21
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (3.249 Å)
Cite:Bypassing evolutionary dead ends and switching the rate-limiting step of a human immunotherapeutic enzyme.
Nat Catal, 5, 2022
7RGW
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BU of 7rgw by Molmil
Crystal structure of HERC2 DOC domain
Descriptor: DI(HYDROXYETHYL)ETHER, E3 ubiquitin-protein ligase HERC2
Authors:Liu, J, Tencer, A.H, Kutateladze, T.G.
Deposit date:2021-07-15
Release date:2022-07-20
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:The ZZ domain of HERC2 is a receptor of arginylated substrates.
Sci Rep, 12, 2022
8DS8
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BU of 8ds8 by Molmil
Crystal structure of human TNRC18 BAH domain in complex with H3K9me3 peptide
Descriptor: Histone H3.1, Trinucleotide repeat-containing gene 18 protein
Authors:Song, J.K, Lu, J.W.
Deposit date:2022-07-21
Release date:2023-08-02
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:TNRC18 engages H3K9me3 to mediate silencing of endogenous retrotransposons.
Nature, 623, 2023
6NPW
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BU of 6npw by Molmil
SSu72/Sympk in complex with Ser2/Ser5 phosphorylated peptide
Descriptor: PHOSPHATE ION, Ser2/Ser5 phosphorylated peptide, Ssu72 ortholog, ...
Authors:Irani, S, Zhang, Y.
Deposit date:2019-01-18
Release date:2019-04-24
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.486 Å)
Cite:Structural determinants for accurate dephosphorylation of RNA polymerase II by its cognate C-terminal domain (CTD) phosphatase during eukaryotic transcription.
J.Biol.Chem., 294, 2019
7N4Z
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BU of 7n4z by Molmil
Complex structure of NOS4 with noscapine
Descriptor: NOS4, SULFATE ION, noscapine
Authors:Kim, W, Zhang, Y.
Deposit date:2021-06-04
Release date:2022-06-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.21 Å)
Cite:Using fungible biosensors to evolve improved alkaloid biosyntheses.
Nat.Chem.Biol., 18, 2022
7N53
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BU of 7n53 by Molmil
Complex structure of PAP4 with papaverine
Descriptor: 1-(3,4-DIMETHOXYBENZYL)-6,7-DIMETHOXYISOQUINOLINE, GLYCEROL, PAP4, ...
Authors:Kim, W, Zhang, Y.
Deposit date:2021-06-04
Release date:2022-06-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Using fungible biosensors to evolve improved alkaloid biosyntheses.
Nat.Chem.Biol., 18, 2022
7N4W
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BU of 7n4w by Molmil
Complex structure of ROTU4 with rotundine
Descriptor: GLYCEROL, ROTU4, SULFATE ION, ...
Authors:Kim, W, Zhang, Y.
Deposit date:2021-06-04
Release date:2022-06-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.64 Å)
Cite:Using fungible biosensors to evolve improved alkaloid biosyntheses.
Nat.Chem.Biol., 18, 2022
7N54
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BU of 7n54 by Molmil
Complex structure of GLAU4 with glaucine
Descriptor: GLAU4, SULFATE ION, glaucine
Authors:Kim, W, Zhang, Y.
Deposit date:2021-06-04
Release date:2022-06-29
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2 Å)
Cite:Using fungible biosensors to evolve improved alkaloid biosyntheses.
Nat.Chem.Biol., 18, 2022

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