Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
9EUU
DownloadVisualize
BU of 9euu by Molmil
Structure of recombinant alpha-synuclein fibrils 1B capable of seeding GCIs in vivo
Descriptor: Alpha-synuclein
Authors:Burger, D, Kashyrina, M, Lewis, A, De Nuccio, F, Mohammed, I, de La Seigliere, H, van den Heuvel, L, Feuillie, C, Verchere, J, Berbon, M, Arotcarena, M, Retailleau, A, Bezard, E, Laferriere, F, Loquet, A, Bousset, L, Baron, T, Lofrumento, D.D, De Giorgi, F, Stahlberg, H, Ichas, F.
Deposit date:2024-03-28
Release date:2024-06-05
Method:ELECTRON MICROSCOPY (1.93 Å)
Cite:Multiple System Atrophy: Insights from aSyn Fibril Structure
To Be Published
3ZO8
DownloadVisualize
BU of 3zo8 by Molmil
Wild-type chorismate mutase of Bacillus subtilis at 1.6 A resolution
Descriptor: CHORISMATE MUTASE AROH
Authors:Burschowsky, D, vanEerde, A, Okvist, M, Kienhofer, A, Kast, P, Hilvert, D, Krengel, U.
Deposit date:2013-02-20
Release date:2014-04-16
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.59 Å)
Cite:Electrostatic Transition State Stabilization Rather Than Reactant Destabilization Provides the Chemical Basis for Efficient Chorismate Mutase Catalysis.
Proc.Natl.Acad.Sci.USA, 111, 2014
3ZP7
DownloadVisualize
BU of 3zp7 by Molmil
Arg90Cit chorismate mutase of Bacillus subtilis in complex with chorismate and prephenate
Descriptor: (3R,4R)-3-[(1-carboxyethenyl)oxy]-4-hydroxycyclohexa-1,5-diene-1-carboxylic acid, CHORISMATE MUTASE AROH, PREPHENIC ACID
Authors:Burschowsky, D, vanEerde, A, Okvist, M, Kienhofer, A, Kast, P, Hilvert, D, Krengel, U.
Deposit date:2013-02-26
Release date:2014-04-16
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Electrostatic Transition State Stabilization Rather Than Reactant Destabilization Provides the Chemical Basis for Efficient Chorismate Mutase Catalysis.
Proc.Natl.Acad.Sci.USA, 111, 2014
3ZP4
DownloadVisualize
BU of 3zp4 by Molmil
Arg90Cit chorismate mutase of Bacillus subtilis in complex with a transition state analog
Descriptor: 8-HYDROXY-2-OXA-BICYCLO[3.3.1]NON-6-ENE-3,5-DICARBOXYLIC ACID, CHORISMATE MUTASE AROH
Authors:Burschowsky, D, vanEerde, A, Okvist, M, Kienhofer, A, Kast, P, Hilvert, D, Krengel, U.
Deposit date:2013-02-26
Release date:2014-04-16
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.798 Å)
Cite:Electrostatic Transition State Stabilization Rather Than Reactant Destabilization Provides the Chemical Basis for Efficient Chorismate Mutase Catalysis.
Proc.Natl.Acad.Sci.USA, 111, 2014
3ZOP
DownloadVisualize
BU of 3zop by Molmil
Arg90Cit chorismate mutase of Bacillus subtilis at 1.6 A resolution
Descriptor: CHORISMATE MUTASE AROH
Authors:Burschowsky, D, vanEerde, A, Okvist, M, Kienhofer, A, Kast, P, Hilvert, D, Krengel, U.
Deposit date:2013-02-22
Release date:2014-04-16
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.61 Å)
Cite:Electrostatic Transition State Stabilization Rather Than Reactant Destabilization Provides the Chemical Basis for Efficient Chorismate Mutase Catalysis.
Proc.Natl.Acad.Sci.USA, 111, 2014
2L4F
DownloadVisualize
BU of 2l4f by Molmil
NMR structure of the UBA domain of S. cerevisiae Dcn1 bound to ubiquitin
Descriptor: Defective in cullin neddylation protein 1
Authors:Burschowsky, D, Mattle, D, Rudolf, F, Peter, M, Wider, G.
Deposit date:2010-10-05
Release date:2011-10-05
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural analysis of the ubiquitin-associated domain (UBA) of yeast Dcn1 in complex with ubiquitin
To be Published
2L4E
DownloadVisualize
BU of 2l4e by Molmil
NMR structure of the UBA domain of S. cerevisiae Dcn1
Descriptor: Defective in cullin neddylation protein 1
Authors:Burschowsky, D, Rudolf, F, Mattle, D, Peter, M, Wider, G.
Deposit date:2010-10-05
Release date:2011-10-05
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural analysis of the ubiquitin-associated domain (UBA) of yeast Dcn1 in complex with ubiquitin
To be Published
5HUC
DownloadVisualize
BU of 5huc by Molmil
DAHP synthase from Corynebacterium glutamicum
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 3-Deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, MANGANESE (II) ION, ...
Authors:Burschowsky, D, Heim, J.B, Thorbjoernsrud, H.V, Krengel, U.
Deposit date:2016-01-27
Release date:2017-08-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Inter-Enzyme Allosteric Regulation of Chorismate Mutase in Corynebacterium glutamicum: Structural Basis of Feedback Activation by Trp.
Biochemistry, 57, 2018
5HUD
DownloadVisualize
BU of 5hud by Molmil
Non-covalent complex of and DAHP synthase and chorismate mutase from Corynebacterium glutamicum with bound transition state analog
Descriptor: 3-Deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, 8-HYDROXY-2-OXA-BICYCLO[3.3.1]NON-6-ENE-3,5-DICARBOXYLIC ACID, Chorismate mutase, ...
Authors:Burschowsky, D, Heim, J.B, Thorbjoernsrud, H.V, Krengel, U.
Deposit date:2016-01-27
Release date:2017-08-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.15 Å)
Cite:Inter-Enzyme Allosteric Regulation of Chorismate Mutase in Corynebacterium glutamicum: Structural Basis of Feedback Activation by Trp.
Biochemistry, 57, 2018
5HUB
DownloadVisualize
BU of 5hub by Molmil
High-resolution structure of chorismate mutase from Corynebacterium glutamicum
Descriptor: Chorismate mutase, FORMIC ACID
Authors:Burschowsky, D, Heim, J.B, Thorbjoernsrud, H.V, Krengel, U.
Deposit date:2016-01-27
Release date:2017-08-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.06 Å)
Cite:Inter-Enzyme Allosteric Regulation of Chorismate Mutase in Corynebacterium glutamicum: Structural Basis of Feedback Activation by Trp.
Biochemistry, 57, 2018
5HUE
DownloadVisualize
BU of 5hue by Molmil
DAHP synthase from Corynebacterium glutamicum in complex with tryptophan
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-Deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase, ...
Authors:Burschowsky, D, Heim, J.B, Thorbjoernsrud, H.V, Krengel, U.
Deposit date:2016-01-27
Release date:2017-08-02
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Inter-Enzyme Allosteric Regulation of Chorismate Mutase in Corynebacterium glutamicum: Structural Basis of Feedback Activation by Trp.
Biochemistry, 57, 2018
2KWV
DownloadVisualize
BU of 2kwv by Molmil
Solution Structure of UBM1 of murine Polymerase iota in Complex with Ubiquitin
Descriptor: DNA polymerase iota, Ubiquitin
Authors:Burschowsky, D, Rudolf, F, Rabut, G, Herrmann, T, Peter, M, Wider, G.
Deposit date:2010-04-20
Release date:2010-10-06
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structural analysis of the conserved ubiquitin-binding motifs (UBMs) of the translesion polymerase iota in complex with ubiquitin.
J.Biol.Chem., 286, 2011
2KWU
DownloadVisualize
BU of 2kwu by Molmil
Solution Structure of UBM2 of murine Polymerase iota in Complex with Ubiquitin
Descriptor: DNA polymerase iota, Ubiquitin
Authors:Burschowsky, D, Rudolf, F, Rabut, G, Herrmann, T, Peter, M, Wider, G.
Deposit date:2010-04-19
Release date:2010-10-06
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Structural analysis of the conserved ubiquitin-binding motifs (UBMs) of the translesion polymerase iota in complex with ubiquitin.
J.Biol.Chem., 286, 2011
6I83
DownloadVisualize
BU of 6i83 by Molmil
Crystal structure of phosphorylated RET V804M tyrosine kinase domain complexed with PDD00018366
Descriptor: 4-[5-(pyridin-3-ylmethylamino)pyrazolo[1,5-a]pyrimidin-3-yl]benzamide, FORMIC ACID, Proto-oncogene tyrosine-protein kinase receptor Ret
Authors:Burschowsky, D, Seewooruthun, C, Bayliss, R, Carr, M.D, Echalier, A, Jordan, A.M.
Deposit date:2018-11-19
Release date:2020-03-11
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (1.88 Å)
Cite:Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RETV804MKinase.
Acs Med.Chem.Lett., 11, 2020
6I82
DownloadVisualize
BU of 6i82 by Molmil
Crystal structure of partially phosphorylated RET V804M tyrosine kinase domain complexed with PDD00018412
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, FORMIC ACID, ...
Authors:Burschowsky, D, Seewooruthun, C, Bayliss, R, Carr, M.D, Echalier, A, Jordan, A.M.
Deposit date:2018-11-19
Release date:2020-03-11
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Discovery and Optimization of wt-RET/KDR-Selective Inhibitors of RETV804MKinase.
Acs Med.Chem.Lett., 11, 2020
6SS4
DownloadVisualize
BU of 6ss4 by Molmil
Structure of arginase-2 in complex with the inhibitory human antigen-binding fragment Fab C0021181
Descriptor: Arginase-2, mitochondrial, Fab C0021181 heavy chain (IgG1), ...
Authors:Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
Deposit date:2019-09-06
Release date:2020-06-10
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.9 Å)
Cite:Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Mabs, 12
6SS2
DownloadVisualize
BU of 6ss2 by Molmil
Structure of arginase-2 in complex with the inhibitory human antigen-binding fragment Fab C0021158
Descriptor: Arginase-2, mitochondrial, Fab C0021158 heavy chain (IgG1), ...
Authors:Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
Deposit date:2019-09-06
Release date:2020-06-10
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Mabs, 12
6SS0
DownloadVisualize
BU of 6ss0 by Molmil
Structure of the arginase-2-inhibitory human antigen-binding fragment Fab C0021181
Descriptor: CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Fab C0021181 heavy chain (IgG1), ...
Authors:Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
Deposit date:2019-09-06
Release date:2020-06-10
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Mabs, 12
6SRV
DownloadVisualize
BU of 6srv by Molmil
Structure of the arginase-2-inhibitory human antigen-binding fragment Fab C0021144
Descriptor: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, ...
Authors:Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
Deposit date:2019-09-06
Release date:2020-06-10
Last modified:2024-11-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Mabs, 12
6SS5
DownloadVisualize
BU of 6ss5 by Molmil
Structure of the arginase-2-inhibitory human antigen-binding fragment Fab C0020187
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ...
Authors:Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
Deposit date:2019-09-06
Release date:2020-06-10
Last modified:2024-11-20
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Extensive sequence and structural evolution of Arginase 2 inhibitory antibodies enabled by an unbiased approach to affinity maturation.
Proc.Natl.Acad.Sci.USA, 117, 2020
6TUL
DownloadVisualize
BU of 6tul by Molmil
Structure of the arginase-2-inhibitory human antigen-binding fragment Fab C0021177
Descriptor: D-MALATE, Fab C0021177 heavy chain (IgG1), Fab C0021177 light chain (IgG1), ...
Authors:Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
Deposit date:2020-01-07
Release date:2020-06-10
Last modified:2024-11-13
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Mabs, 12
6SRX
DownloadVisualize
BU of 6srx by Molmil
Structure of the arginase-2-inhibitory human antigen-binding fragment Fab C0021158
Descriptor: ACETATE ION, CHLORIDE ION, Fab C0021158 heavy chain (IgG1), ...
Authors:Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
Deposit date:2019-09-06
Release date:2020-06-10
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural and functional characterization of C0021158, a high-affinity monoclonal antibody that inhibits Arginase 2 function via a novel non-competitive mechanism of action.
Mabs, 12
6SS6
DownloadVisualize
BU of 6ss6 by Molmil
Structure of arginase-2 in complex with the inhibitory human antigen-binding fragment Fab C0020187
Descriptor: Arginase-2, mitochondrial, Fab C0020187 heavy chain (IgG1), ...
Authors:Burschowsky, D, Addyman, A, Fiedler, S, Groves, M, Haynes, S, Seewooruthun, C, Carr, M.
Deposit date:2019-09-06
Release date:2020-06-10
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.25 Å)
Cite:Extensive sequence and structural evolution of Arginase 2 inhibitory antibodies enabled by an unbiased approach to affinity maturation.
Proc.Natl.Acad.Sci.USA, 117, 2020
5IN7
DownloadVisualize
BU of 5in7 by Molmil
X-RAY STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN
Descriptor: Neuronal migration protein doublecortin
Authors:Ruf, A, Benz, J, Burger, D, D'Arcy, B, Debulpaep, M, Di Lello, P, Fry, D, Huber, W, Kremer, T, Laeremans, T, Matile, H, Ross, A, Rudolph, M.G, Rufer, A.C, Sharma, A, Steinmetz, M.O, Steyaert, J, Schoch, G, Stihle, M, Thoma, R.
Deposit date:2016-03-07
Release date:2016-03-23
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies.
J.Biol.Chem., 291, 2016
5IO9
DownloadVisualize
BU of 5io9 by Molmil
X-RAY STRUCTURE OF THE N-TERMINAL DOMAIN OF HUMAN DOUBLECORTIN
Descriptor: Neuronal migration protein doublecortin
Authors:Ruf, A, Benz, J, Burger, D, D'Arcy, B, Debulpaep, M, Di Lello, P, Fry, D, Huber, W, Kremer, T, Laeremans, T, Matile, H, Ross, A, Rudolph, M.G, Rufer, A.C, Sharma, A, Steinmetz, M.O, Steyaert, J, Schoch, G, Stihle, M, Thoma, R.
Deposit date:2016-03-08
Release date:2016-03-23
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal Structures of the Human Doublecortin C- and N-terminal Domains in Complex with Specific Antibodies.
J.Biol.Chem., 291, 2016

227561

PDB entries from 2024-11-20

PDB statisticsPDBj update infoContact PDBjnumon