2Q1H
| Ancestral Corticoid Receptor in Complex with Aldosterone | Descriptor: | ALDOSTERONE, AncCR, GLYCEROL, ... | Authors: | Ortlund, E.A, Bridgham, J.T, Redinbo, M.R, Thornton, J.W. | Deposit date: | 2007-05-24 | Release date: | 2007-09-04 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of an ancient protein: evolution by conformational epistasis. Science, 317, 2007
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2Q3Y
| Ancestral Corticiod Receptor in Complex with DOC | Descriptor: | Ancestral Corticiod Receptor, DESOXYCORTICOSTERONE, GLYCEROL, ... | Authors: | Ortlund, E.A, Bridgham, J.T, Redinbo, M.R, Thornton, J.W. | Deposit date: | 2007-05-30 | Release date: | 2007-09-04 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of an ancient protein: evolution by conformational epistasis Science, 317, 2007
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4N1Y
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3GN8
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2Q1V
| Ancestral corticoid receptor in complex with cortisol | Descriptor: | 17,21-DIHYDROXYPREGNA-1,4-DIENE-3,11,20-TRIONE, AncCR, GLYCEROL | Authors: | Ortlund, E.A, Redinbo, M.R. | Deposit date: | 2007-05-25 | Release date: | 2007-09-04 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Crystal structure of an ancient protein: evolution by conformational epistasis. Science, 317, 2007
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4OND
| Ancestral Steroid Receptor 2 DBD helix mutant - ERE DNA complex | Descriptor: | 5'-D(*CP*CP*AP*GP*GP*TP*CP*AP*GP*AP*GP*TP*GP*AP*CP*CP*TP*G)-3', 5'-D(*TP*CP*AP*GP*GP*TP*CP*AP*CP*TP*CP*TP*GP*AP*CP*CP*TP*G)-3', Ancestral SR2 Helix Mutant, ... | Authors: | Ortlund, E.O, Murphy, M.N. | Deposit date: | 2014-01-28 | Release date: | 2014-10-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.253 Å) | Cite: | Evolution of DNA specificity in a transcription factor family produced a new gene regulatory module. Cell(Cambridge,Mass.), 159, 2014
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4OLN
| Ancestral Steroid Receptor 1 in complex with estrogen response element DNA | Descriptor: | 5'-D(*CP*CP*AP*GP*GP*TP*CP*AP*GP*AP*GP*TP*GP*AP*CP*CP*TP*GP*A)-3', 5'-D(*TP*CP*AP*GP*GP*TP*CP*AP*CP*TP*CP*TP*GP*AP*CP*CP*TP*GP*G)-3', AncSR1, ... | Authors: | Ortlund, E.O, Murphy, M.N. | Deposit date: | 2014-01-24 | Release date: | 2014-10-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Evolution of DNA specificity in a transcription factor family produced a new gene regulatory module. Cell(Cambridge,Mass.), 159, 2014
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4OV7
| Ancestral Steroid Receptor 2 DBD helix mutant - SRE DNA complex | Descriptor: | 5'-D(*CP*CP*AP*GP*AP*AP*CP*AP*GP*AP*GP*TP*GP*TP*TP*CP*TP*G)-3', 5'-D(*TP*CP*AP*GP*AP*AP*CP*AP*CP*TP*CP*TP*GP*TP*TP*CP*TP*G)-3', Ancestral Steroid Receptor 2 DBD helix mutant, ... | Authors: | Ortlund, E.A. | Deposit date: | 2014-02-20 | Release date: | 2014-10-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.701 Å) | Cite: | Evolution of DNA specificity in a transcription factor family produced a new gene regulatory module. Cell(Cambridge,Mass.), 159, 2014
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4OOR
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