2Q3Y

Ancestral Corticiod Receptor in Complex with DOC

Summary for 2Q3Y

• Entry DOI: 10.2210/pdb2q3y/pdb
• Related: 2Q1H 2Q1V
• Descriptor: Ancestral Corticiod Receptor, Nuclear receptor 0B2, DESOXYCORTICOSTERONE, ... (5 entities in total)
• Functional Keywords: nuclear receptor, mineralocoticiod, ligand binding domain, doc, cortisol, evolution, transcription
• Biological source: unidentified
• Cellular location: Nucleus: Q15466
• Total number of polymer chains: 2
• Total formula weight: 30406.27

Authors

Ortlund, E.A.,Bridgham, J.T.,Redinbo, M.R.,Thornton, J.W. (deposition date: 2007-05-30, release date: 2007-09-04, Last modification date: 2024-04-03)

• Primary citation: Ortlund, E.A.,Bridgham, J.T.,Redinbo, M.R.,Thornton, J.W.; Crystal structure of an ancient protein: evolution by conformational epistasis; Science, 317:1544-1548, 2007; PubMed: 17702911; DOI: 10.1126/science.1142819

Experimental method

X-RAY DIFFRACTION (2.4 Å)