4N6N
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4N1K
| Crystal structures of NLRP14 pyrin domain reveal a conformational switch mechanism, regulating its molecular interactions | 分子名称: | NACHT, LRR and PYD domains-containing protein 14 | 著者 | Eibl, C, Hessenberger, M, Wenger, J, Brandstetter, H. | 登録日 | 2013-10-04 | 公開日 | 2014-07-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structures of the NLRP14 pyrin domain reveal a conformational switch mechanism regulating its molecular interactions. Acta Crystallogr.,Sect.D, 70, 2014
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1JH1
| Crystal Structure of MMP-8 complexed with a 6H-1,3,4-thiadiazine derived inhibitor | 分子名称: | BUT-3-ENYL-[5-(4-CHLORO-PHENYL)-3,6-DIHYDRO-[1,3,4]THIADIAZIN-2-YLIDENE]-AMINE, CALCIUM ION, Matrix Metalloproteinase 8, ... | 著者 | Schroder, J, Henke, A, Wenzel, H, Brandstetter, H, Stammler, H.G, Stammler, A, Pfeiffer, W.D, Tschesche, H. | 登録日 | 2001-06-27 | 公開日 | 2001-12-27 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure-based design and synthesis of potent matrix metalloproteinase inhibitors derived from a 6H-1,3,4-thiadiazine scaffold. J.Med.Chem., 44, 2001
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4NFF
| Human kallikrein-related peptidase 2 in complex with PPACK | 分子名称: | D-phenylalanyl-N-[(2S,3S)-6-{[amino(iminio)methyl]amino}-1-chloro-2-hydroxyhexan-3-yl]-L-prolinamide, Kallikrein-2 | 著者 | Skala, W, Brandstetter, H, Magdolen, V, Goettig, P. | 登録日 | 2013-10-31 | 公開日 | 2014-10-29 | 最終更新日 | 2017-11-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure-function analyses of human kallikrein-related peptidase 2 establish the 99-loop as master regulator of activity J.Biol.Chem., 289, 2014
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4NFE
| Human kallikrein-related peptidase 2 in complex with benzamidine | 分子名称: | BENZAMIDINE, Kallikrein-2, SULFATE ION | 著者 | Skala, W, Brandstetter, H, Magdolen, V, Goettig, P. | 登録日 | 2013-10-31 | 公開日 | 2014-10-29 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure-function analyses of human kallikrein-related peptidase 2 establish the 99-loop as master regulator of activity J.Biol.Chem., 289, 2014
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1J2Q
| 20S proteasome in complex with calpain-Inhibitor I from archaeoglobus fulgidus | 分子名称: | 2-ACETYLAMINO-4-METHYL-PENTANOIC ACID [1-(1-FORMYL-PENTYLCARBAMOYL)-3-METHYL-BUTYL]-AMIDE, Proteasome alpha subunit, Proteasome beta subunit | 著者 | Groll, M, Brandstetter, H, Bartunik, H, Bourenkow, G, Huber, R. | 登録日 | 2003-01-08 | 公開日 | 2003-03-18 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.83 Å) | 主引用文献 | Investigations on the Maturation and Regulation of Archaebacterial Proteasomes J.MOL.BIOL., 327, 2003
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1J2P
| alpha-ring from the proteasome from archaeoglobus fulgidus | 分子名称: | Proteasome alpha subunit | 著者 | Groll, M, Brandstetter, H, Bartunik, H, Bourenkow, G, Huber, R. | 登録日 | 2003-01-08 | 公開日 | 2003-03-18 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | 主引用文献 | Investigations on the Maturation and Regulation of Archaebacterial Proteasomes J.MOL.BIOL., 327, 2003
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1ITV
| Dimeric form of the haemopexin domain of MMP9 | 分子名称: | MMP9, SULFATE ION | 著者 | Cha, H, Kopetzki, E, Huber, R, Lanzendoerfer, M, Brandstetter, H. | 登録日 | 2002-02-11 | 公開日 | 2002-09-04 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Structural basis of the adaptive molecular recognition by MMP9. J.Mol.Biol., 320, 2002
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1RFN
| HUMAN COAGULATION FACTOR IXA IN COMPLEX WITH P-AMINO BENZAMIDINE | 分子名称: | CALCIUM ION, P-AMINO BENZAMIDINE, PROTEIN (COAGULATION FACTOR IX), ... | 著者 | Hopfner, K.-P, Lang, A, Karcher, A, Sichler, K, Kopetzki, E, Brandstetter, H, Huber, R, Bode, W, Engh, R.A. | 登録日 | 1999-04-19 | 公開日 | 1999-09-01 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Coagulation factor IXa: the relaxed conformation of Tyr99 blocks substrate binding. Structure Fold.Des., 7, 1999
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1S0P
| Structure of the N-Terminal Domain of the Adenylyl Cyclase-Associated Protein (CAP) from Dictyostelium discoideum. | 分子名称: | Adenylyl cyclase-associated protein, MAGNESIUM ION | 著者 | Ksiazek, D, Brandstetter, H, Israel, L, Bourenkov, G.P, Katchalova, G, Janssen, K.P, Bartunik, H.D, Noegel, A.A, Schleicher, M, Holak, T.A. | 登録日 | 2004-01-01 | 公開日 | 2004-01-27 | 最終更新日 | 2024-02-14 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | STRUCTURE OF THE N-TERMINAL DOMAIN OF THE ADENYLYL
CYCLASE-ASSOCIATED PROTEIN (CAP) FROM DICTYOSTELIUM DISCOIDEUM Structure, 11, 2003
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1XRP
| Crystal structure of active site F1-mutant E213Q soaked with peptide Pro-Leu-Gly-Gly | 分子名称: | PLGG, PROLINE, Proline iminopeptidase | 著者 | Goettig, P, Brandstetter, H, Groll, M, Goehring, W, Konarev, P.V, Svergun, D.I, Huber, R, Kim, J.-S. | 登録日 | 2004-10-15 | 公開日 | 2005-07-12 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum J.Biol.Chem., 280, 2005
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1XQY
| Crystal structure of F1-mutant S105A complex with PRO-LEU-GLY-GLY | 分子名称: | PLGG, PROLINE, Proline iminopeptidase | 著者 | Goettig, P, Brandstetter, H, Groll, M, Goehring, W, Konarev, P.V, Svergun, D.I, Huber, R, Kim, J.-S. | 登録日 | 2004-10-13 | 公開日 | 2005-07-12 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum J.Biol.Chem., 280, 2005
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1XQX
| Crystal structure of F1-mutant S105A complex with PCK | 分子名称: | PHENYLALANYLMETHYLCHLORIDE, Proline iminopeptidase | 著者 | Goettig, P, Brandstetter, H, Groll, M, Goehring, W, Konarev, P.V, Svergun, D.I, Huber, R, Kim, J.-S. | 登録日 | 2004-10-13 | 公開日 | 2005-07-12 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum J.Biol.Chem., 280, 2005
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1XRM
| Crystal structure of active site F1-mutant E213Q soaked with peptide Ala-Phe | 分子名称: | ALANINE, PHENYLALANINE, Proline iminopeptidase | 著者 | Goettig, P, Brandstetter, H, Groll, M, Goehring, W, Konarev, P.V, Svergun, D.I, Huber, R, Kim, J.-S. | 登録日 | 2004-10-15 | 公開日 | 2005-07-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum J.Biol.Chem., 280, 2005
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1XRR
| Crystal structure of active site F1-mutant E245Q soaked with peptide Pro-Pro | 分子名称: | PROLINE, Proline iminopeptidase | 著者 | Goettig, P, Brandstetter, H, Groll, M, Goehring, W, Konarev, P.V, Svergun, D.I, Huber, R, Kim, J.-S. | 登録日 | 2004-10-15 | 公開日 | 2005-07-12 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum J.Biol.Chem., 280, 2005
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1XRN
| Crystal structure of active site F1-mutant E213Q soaked with peptide Phe-Ala | 分子名称: | ALANINE, Proline iminopeptidase | 著者 | Goettig, P, Brandstetter, H, Groll, M, Goehring, W, Konarev, P.V, Svergun, D.I, Huber, R, Kim, J.-S. | 登録日 | 2004-10-15 | 公開日 | 2005-07-12 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum J.Biol.Chem., 280, 2005
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1XQV
| Crystal structure of inactive F1-mutant G37A | 分子名称: | Proline iminopeptidase | 著者 | Goettig, P, Brandstetter, H, Groll, M, Goehring, W, Konarev, P.V, Svergun, D.I, Huber, R, Kim, J.-S. | 登録日 | 2004-10-13 | 公開日 | 2005-07-12 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum J.Biol.Chem., 280, 2005
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1XRL
| Crystal structure of active site F1-mutant Y205F complex with inhibitor PCK | 分子名称: | (2R,3S)-3-AMINO-1-CHLORO-4-PHENYL-BUTAN-2-OL, Proline iminopeptidase | 著者 | Goettig, P, Brandstetter, H, Groll, M, Goehring, W, Konarev, P.V, Svergun, D.I, Huber, R, Kim, J.-S. | 登録日 | 2004-10-15 | 公開日 | 2005-07-12 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum J.Biol.Chem., 280, 2005
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1XRQ
| Crystal structure of active site F1-mutant E245Q soaked with peptide Phe-Leu | 分子名称: | LEUCINE, Proline iminopeptidase | 著者 | Goettig, P, Brandstetter, H, Groll, M, Goehring, W, Konarev, P.V, Svergun, D.I, Huber, R, Kim, J.-S. | 登録日 | 2004-10-15 | 公開日 | 2005-07-12 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum J.Biol.Chem., 280, 2005
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1XQW
| Crystal structure of F1-mutant S105A complex with PHE-LEU | 分子名称: | LEUCINE, PHENYLALANINE, Proline iminopeptidase | 著者 | Goettig, P, Brandstetter, H, Groll, M, Goehring, W, Konarev, P.V, Svergun, D.I, Huber, R, Kim, J.-S. | 登録日 | 2004-10-13 | 公開日 | 2005-07-12 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum J.Biol.Chem., 280, 2005
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1XRO
| Crystal structure of active site F1-mutant E213Q soaked with peptide Phe-Leu | 分子名称: | LEUCINE, Proline iminopeptidase | 著者 | Goettig, P, Brandstetter, H, Groll, M, Goehring, W, Konarev, P.V, Svergun, D.I, Huber, R, Kim, J.-S. | 登録日 | 2004-10-15 | 公開日 | 2005-07-12 | 最終更新日 | 2021-11-10 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | X-ray snapshots of peptide processing in mutants of tricorn-interacting factor F1 from Thermoplasma acidophilum J.Biol.Chem., 280, 2005
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1Z1W
| Crystal structures of the tricorn interacting facor F3 from Thermoplasma acidophilum, a zinc aminopeptidase in three different conformations | 分子名称: | SULFATE ION, Tricorn protease interacting factor F3, ZINC ION | 著者 | Kyrieleis, O.J.P, Goettig, P, Kiefersauer, R, Huber, R, Brandstetter, H. | 登録日 | 2005-03-07 | 公開日 | 2005-05-31 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Crystal Structures of the Tricorn Interacting Factor F3 from Thermoplasma acidophilum, a Zinc Aminopeptidase in Three Different Conformations J.MOL.BIOL., 394, 2005
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1Z5H
| Crystal structures of the Tricorn interacting Factor F3 from Thermoplasma acidophilum | 分子名称: | SULFATE ION, Tricorn protease interacting factor F3, ZINC ION | 著者 | Kyrieleis, O.J.P, Goettig, P, Kiefersauer, R, Huber, R, Brandstetter, H. | 登録日 | 2005-03-18 | 公開日 | 2005-06-28 | 最終更新日 | 2024-03-13 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Crystal Structures of the Tricorn Interacting Factor F3 from Thermoplasma acidophilum, a Zinc Aminopeptidase in Three Different Conformations J.MOL.BIOL., 349, 2005
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1ZRZ
| Crystal Structure of the Catalytic Domain of Atypical Protein Kinase C-iota | 分子名称: | 3-{1-[3-(DIMETHYLAMINO)PROPYL]-1H-INDOL-3-YL}-4-(1H-INDOL-3-YL)-1H-PYRROLE-2,5-DIONE, Protein kinase C, iota | 著者 | Messerschmidt, A, Macieira, S, Velarde, M, Baedeker, M, Benda, C, Jestel, A, Brandstetter, H, Neuefeind, T, Blaesse, M, Structural Proteomics in Europe (SPINE) | 登録日 | 2005-05-23 | 公開日 | 2005-09-13 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Crystal Structure of the Catalytic Domain of Human Atypical Protein Kinase C-iota Reveals Interaction Mode of Phosphorylation Site in Turn Motif J.Mol.Biol., 352, 2005
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1KLI
| Cofactor-and substrate-assisted activation of factor VIIa | 分子名称: | BENZAMIDINE, CALCIUM ION, GLYCEROL, ... | 著者 | Sichler, K, Banner, D.W, D'Arcy, A, Hopfner, K.P, Huber, R, Bode, W, Kresse, G.B, Kopetzki, E, Brandstetter, H. | 登録日 | 2001-12-12 | 公開日 | 2002-09-18 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.69 Å) | 主引用文献 | Crystal Structure of Uninhibited Factor VIIa Link its Cofactor and Substrate-assisted Activation to Specific Interactions J.Mol.Biol., 322, 2002
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