3OK0
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![BU of 3ok0 by Molmil](/molmil-images/mine/3ok0) | E35A Mutant of Hen Egg White Lysozyme (HEWL) | Descriptor: | CHLORIDE ION, Lysozyme C, SODIUM ION | Authors: | O'Meara, F, Bradley, J, O'Rourke, P.E, Webb, H, Tynan-Connolly, B.M, Nielsen, J.E. | Deposit date: | 2010-08-24 | Release date: | 2011-03-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | E35A Mutant of Hen Egg White Lysozyme (HEWL) TO BE PUBLISHED
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3OJP
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![BU of 3ojp by Molmil](/molmil-images/mine/3ojp) | D52N Mutant of Hen Egg White Lysozyme (HEWL) | Descriptor: | ACETATE ION, CHLORIDE ION, Lysozyme C, ... | Authors: | O'Meara, F, Bradley, J, O'Rourke, P.E, Webb, H, Tynan-Connolly, B.M, Nielsen, J.E. | Deposit date: | 2010-08-23 | Release date: | 2011-03-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | D52N Mutant of Hen Egg White Lysozyme (HEWL) TO BE PUBLISHED
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6PZ4
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![BU of 6pz4 by Molmil](/molmil-images/mine/6pz4) | co-crystal structure of BACE with inhibitor AM-6494 | Descriptor: | Beta-secretase 1, GLYCEROL, IODIDE ION, ... | Authors: | Huang, X. | Deposit date: | 2019-07-31 | Release date: | 2019-10-23 | Last modified: | 2020-03-25 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Discovery of AM-6494: A Potent and Orally Efficacious beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 (BACE1) Inhibitor with in Vivo Selectivity over BACE2. J.Med.Chem., 63, 2020
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3PMQ
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![BU of 3pmq by Molmil](/molmil-images/mine/3pmq) | |
6B8O
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![BU of 6b8o by Molmil](/molmil-images/mine/6b8o) | WT Ig-like V Domain with Phosphatidylserine | Descriptor: | 1,2-DICAPROYL-SN-PHOSPHATIDYL-L-SERINE, 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Sudom, A, Wang, Z. | Deposit date: | 2017-10-09 | Release date: | 2018-06-27 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Molecular basis for the loss-of-function effects of the Alzheimer's disease-associated R47H variant of the immune receptor TREM2. J. Biol. Chem., 293, 2018
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4LPN
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![BU of 4lpn by Molmil](/molmil-images/mine/4lpn) | Frog M-ferritin with cobalt, D127E mutant | Descriptor: | CHLORIDE ION, COBALT (II) ION, Ferritin, ... | Authors: | Torres, R, Behera, R, Goulding, C.W. | Deposit date: | 2013-07-16 | Release date: | 2014-07-16 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | D127E ion channel exit modification in ferritin nanocages entraps Fe(II) and impairs its distribution to diiron catalytic centers To be Published
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4LPM
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![BU of 4lpm by Molmil](/molmil-images/mine/4lpm) | Frog M-ferritin with magnesium, D127E mutant | Descriptor: | CHLORIDE ION, Ferritin, middle subunit, ... | Authors: | Torres, R, Behera, R, Goulding, C.W, Theil, E.C. | Deposit date: | 2013-07-16 | Release date: | 2014-07-16 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | D127E ion channel exit modification in ferritin nanocages entraps Fe(II) and impairs its distribution to diiron catalytic centers To be Published
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5UD8
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![BU of 5ud8 by Molmil](/molmil-images/mine/5ud8) | Crystal Structure of Mutant Ig-like Domain | Descriptor: | Triggering receptor expressed on myeloid cells 2 | Authors: | Sudom, A, Min, X, Wang, Z. | Deposit date: | 2016-12-23 | Release date: | 2018-04-04 | Last modified: | 2019-04-17 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Molecular basis for the loss-of-function effects of the Alzheimer's disease-associated R47H variant of the immune receptor TREM2. J. Biol. Chem., 293, 2018
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5UD7
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![BU of 5ud7 by Molmil](/molmil-images/mine/5ud7) | Crystal Structure of Wild-Type Ig-like Domain | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, IODIDE ION, SULFATE ION, ... | Authors: | Sudom, A, Min, X, Wang, Z. | Deposit date: | 2016-12-23 | Release date: | 2018-04-04 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.20002246 Å) | Cite: | Molecular basis for the loss-of-function effects of the Alzheimer's disease-associated R47H variant of the immune receptor TREM2. J. Biol. Chem., 293, 2018
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