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1BI5
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CHALCONE SYNTHASE FROM ALFALFA
分子名称: CHALCONE SYNTHASE
著者Ferrer, J.L, Jez, J.M, Bowman, M.E, Dixon, R.A, Noel, J.P.
登録日1998-06-22
公開日1999-06-22
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Structure of chalcone synthase and the molecular basis of plant polyketide biosynthesis.
Nat.Struct.Biol., 6, 1999
6MS8
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Crystal Structure of Chalcone Isomerase from Medicago Truncatula Complexed with (2S) Naringenin
分子名称: Chalcone-flavonone isomerase family protein, NARINGENIN
著者Burke, J.R, La Clair, J.J, Philippe, R.N, Pabis, A, Jez, J.M, Cortina, G, Kaltenbach, M, Bowman, M.E, Woods, K.B, Nelson, A.T, Tawfik, D.S, Kamerlin, S.C.L, Noel, J.P.
登録日2018-10-16
公開日2019-08-21
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Bifunctional Substrate Activation via an Arginine Residue Drives Catalysis in Chalcone Isomerases
Acs Catalysis, 2019
8DLE
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Crosslinked Crystal Structure of the 8-amino-7-oxonanoate synthase, BioF, and Benzene Sulfonyl Fluoride-crypto Acyl Carrier Protein, BSF-ACP
分子名称: 1,2-ETHANEDIOL, 8-amino-7-oxononanoate synthase, Acyl carrier protein, ...
著者Chen, A, Davis, T.D, Louie, G.V, Bowman, M.E, Noel, J.P, Burkart, M.D.
登録日2022-07-07
公開日2023-07-12
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crosslinked Crystal Structure of the 8-amino-7-oxonanoate synthase, BioF, and Benzene Sulfonyl Fluoride-crypto Acyl Carrier Protein, BSF-ACP.
To Be Published
6CJO
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Crystal Structure of Chalcone Isomerase from Medicago Sativa with the G95S mutation.
分子名称: Chalcone--flavonone isomerase 1, SULFATE ION
著者Burke, J.R, La Clair, J.J, Philippe, R.N, Pabis, A, Jez, J.M, Cortina, G, Kaltenbach, M, Bowman, M.E, Woods, K.B, Nelson, A.T, Tawfik, D.S, Kamerlin, S.C.L, Noel, J.P.
登録日2018-02-26
公開日2019-03-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Bifunctional Substrate Activation via an Arginine Residue Drives Catalysis in Chalcone Isomerases
Acs Catalysis, 2019
6CJN
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Crystal Structure of Chalcone Isomerase from Medicago Sativa with the G95T mutation
分子名称: Chalcone--flavonone isomerase 1, SULFATE ION
著者Burke, J.R, La Clair, J.J, Philippe, R.N, Pabis, A, Jez, J.M, Cortina, G, Kaltenbach, M, Bowman, M.E, Woods, K.B, Nelson, A.T, Tawfik, D.S, Kamerlin, S.C.L, Noel, J.P.
登録日2018-02-26
公開日2019-03-13
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Bifunctional Substrate Activation via an Arginine Residue Drives Catalysis in Chalcone Isomerases
Acs Catalysis, 2019
4R1T
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Crystal structure of Petunia hydrida cinnamoyl-CoA reductase
分子名称: cinnamoyl CoA reductase, molecular iodine
著者Noel, J.P, Louie, G.V, Bowman, M.E, Bomati, E.K.
登録日2014-08-07
公開日2014-10-01
最終更新日2014-11-12
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural Studies of Cinnamoyl-CoA Reductase and Cinnamyl-Alcohol Dehydrogenase, Key Enzymes of Monolignol Biosynthesis.
Plant Cell, 26, 2014
4R1U
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Crystal structure of Medicago truncatula cinnamoyl-CoA reductase
分子名称: ACETATE ION, Cinnamoyl CoA reductase
著者Noel, J.P, Bomati, E.K, Louie, G.V, Bowman, M.E.
登録日2014-08-07
公開日2014-10-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Structural Studies of Cinnamoyl-CoA Reductase and Cinnamyl-Alcohol Dehydrogenase, Key Enzymes of Monolignol Biosynthesis.
Plant Cell, 26, 2014
4R1S
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Crystal structure of Petunia hydrida cinnamoyl-CoA reductase
分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, cinnamoyl CoA reductase
著者Noel, J.P, Louie, G.V, Bowman, M.E, Bomati, E.K.
登録日2014-08-07
公開日2014-10-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural Studies of Cinnamoyl-CoA Reductase and Cinnamyl-Alcohol Dehydrogenase, Key Enzymes of Monolignol Biosynthesis.
Plant Cell, 26, 2014
1ZCN
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human Pin1 Ng mutant
分子名称: PENTAETHYLENE GLYCOL, PHOSPHATE ION, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Jager, M, Zhang, Y, Nguyen, H, Dendel, G, Bowman, M.E, Gruebele, M, Noel, J.P, Kelly, J.W.
登録日2005-04-12
公開日2006-06-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structure-function-folding relationship in a WW domain.
Proc.Natl.Acad.Sci.Usa, 103, 2006
1ZGD
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Chalcone Reductase Complexed With NADP+ at 1.7 Angstrom Resolution
分子名称: NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, chalcone reductase
著者Bomati, E.K, Austin, M.B, Bowman, M.E, Dixon, R.A, Noel, J.P.
登録日2005-04-21
公開日2005-06-28
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Structural elucidation of chalcone reductase and implications for deoxychalcone biosynthesis
J.Biol.Chem., 280, 2005
1JX1
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Chalcone Isomerase--T48A mutant
分子名称: 7-HYDROXY-2-(4-HYDROXY-PHENYL)-CHROMAN-4-ONE, CHALCONE--FLAVONONE ISOMERASE 1, SULFATE ION
著者Jez, J.M, Bowman, M.E, Noel, J.P.
登録日2001-09-05
公開日2002-07-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Role of Hydrogen Bonds in the Reaction Mechanism of Chalcone Isomerase
Biochemistry, 41, 2002
1JX0
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Chalcone Isomerase--Y106F mutant
分子名称: 7-HYDROXY-2-(4-HYDROXY-PHENYL)-CHROMAN-4-ONE, CHALCONE--FLAVONONE ISOMERASE 1, SULFATE ION
著者Jez, J.M, Bowman, M.E, Noel, J.P.
登録日2001-09-05
公開日2002-07-24
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献Role of Hydrogen Bonds in the Reaction Mechanism of Chalcone Isomerase
Biochemistry, 41, 2002
1KNJ
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Co-Crystal Structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate Synthase (ispF) from E. coli Involved in Mevalonate-Independent Isoprenoid Biosynthesis, Complexed with CMP/MECDP/Mn2+
分子名称: 2C-METHYL-D-ERYTHRITOL 2,4-CYCLODIPHOSPHATE, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, CYTIDINE-5'-MONOPHOSPHATE, ...
著者Richard, S.B, Ferrer, J.L, Bowman, M.E, Lillo, A.M, Tetzlaff, C.N, Cane, D.E, Noel, J.P.
登録日2001-12-18
公開日2002-06-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure and mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. An enzyme in the mevalonate-independent isoprenoid biosynthetic pathway.
J.Biol.Chem., 277, 2002
1KNK
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Crystal Structure of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate Synthase (ispF) from E. coli involved in Mevalonate-Independent Isoprenoid Biosynthesis
分子名称: 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MANGANESE (II) ION
著者Richard, S.B, Ferrer, J.L, Bowman, M.E, Lillo, A.M, Tetzlaff, C.N, Cane, D.E, Noel, J.P.
登録日2001-12-18
公開日2002-06-18
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structure and mechanism of 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase. An enzyme in the mevalonate-independent isoprenoid biosynthetic pathway.
J.Biol.Chem., 277, 2002
1D6I
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CHALCONE SYNTHASE (H303Q MUTANT)
分子名称: CHALCONE SYNTHASE, SULFATE ION
著者Jez, J.M, Ferrer, J.L, Bowman, M.E, Dixon, R.A, Noel, J.P.
登録日1999-10-13
公開日2000-02-03
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase.
Biochemistry, 39, 2000
1D6F
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CHALCONE SYNTHASE C164A MUTANT
分子名称: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHALCONE SYNTHASE, SULFATE ION
著者Jez, J.M, Ferrer, J.L, Bowman, M.E, Dixon, R.A, Noel, J.P.
登録日1999-10-13
公開日2000-02-03
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.69 Å)
主引用文献Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase.
Biochemistry, 39, 2000
1D6H
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CHALONE SYNTHASE (N336A MUTANT COMPLEXED WITH COA)
分子名称: CHALCONE SYNTHASE, COENZYME A, SULFATE ION
著者Jez, J.M, Ferrer, J.L, Bowman, M.E, Dixon, R.A, Noel, J.P.
登録日1999-10-13
公開日2000-02-03
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Dissection of malonyl-coenzyme A decarboxylation from polyketide formation in the reaction mechanism of a plant polyketide synthase.
Biochemistry, 39, 2000
2F21
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human Pin1 Fip mutant
分子名称: PENTAETHYLENE GLYCOL, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
著者Jager, M, Zhang, Y, Bowman, M.E, Noel, J.P, Kelly, J.W.
登録日2005-11-15
公開日2006-06-20
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure-function-folding relationship in a WW domain.
Proc.Natl.Acad.Sci.Usa, 103, 2006
1U0U
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An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases: Pine stilbene synthase structure
分子名称: Dihydropinosylvin synthase
著者Austin, M.B, Bowman, M.E, Ferrer, J.-L, Schroder, J, Noel, J.P.
登録日2004-07-14
公開日2004-10-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases
Chem.Biol., 11, 2004
1U0W
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An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases: 18xCHS+resveratrol Structure
分子名称: Chalcone synthase 2, RESVERATROL
著者Austin, M.B, Bowman, M.E, Ferrer, J.-L, Schroder, J, Noel, J.P.
登録日2004-07-14
公開日2004-10-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases
Chem.Biol., 11, 2004
1U0V
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An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization of Specificity of Type III Polyketide Synthases: 18xCHS structure
分子名称: Chalcone synthase 2
著者Austin, M.B, Bowman, M.E, Ferrer, J.-L, Schroder, J, Noel, J.P.
登録日2004-07-14
公開日2004-10-12
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献An Aldol Switch Discovered in Stilbene Synthases Mediates Cyclization Specificity of Type III Polyketide Synthases
Chem.Biol., 11, 2004
1U0M
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Crystal Structure of 1,3,6,8-Tetrahydroxynaphthalene Synthase (THNS) from Streptomyces coelicolor A3(2): a Bacterial Type III Polyketide Synthase (PKS) Provides Insights into Enzymatic Control of Reactive Polyketide Intermediates
分子名称: GLYCEROL, POLYETHYLENE GLYCOL (N=34), putative polyketide synthase
著者Austin, M.B, Izumikawa, M, Bowman, M.E, Udwary, D.W, Ferrer, J.L, Moore, B.S, Noel, J.P.
登録日2004-07-13
公開日2004-09-14
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Crystal structure of a bacterial type III polyketide synthase and enzymatic control of reactive polyketide intermediates
J.Biol.Chem., 279, 2004
2H84
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Crystal Structure of the C-terminal Type III Polyketide Synthase (PKS III) Domain of 'Steely1' (a Type I/III PKS Hybrid from Dictyostelium)
分子名称: HEXAETHYLENE GLYCOL, Steely1
著者Austin, M.B, Saito, T, Bowman, M.E, Haydock, S, Kato, A, Moore, B.S, Kay, R.R, Noel, J.P.
登録日2006-06-06
公開日2006-08-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Biosynthesis of Dictyostelium discoideum differentiation-inducing factor by a hybrid type I fatty acid-type III polyketide synthase.
Nat.Chem.Biol., 2, 2006
4DOO
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Crystal structure of Arabidopsis thaliana fatty-acid binding protein At3g63170 (AtFAP1)
分子名称: Chalcone-flavanone isomerase family protein, LAURIC ACID, POTASSIUM ION
著者Noel, J.P, Pojer, F, Louie, G.V, Bowman, M.E.
登録日2012-02-09
公開日2012-05-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Evolution of the chalcone-isomerase fold from fatty-acid binding to stereospecific catalysis.
Nature, 485, 2012
4DOK
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Crystal structure of Arabidopsis thaliana chalcone-isomerase like protein At5g05270 (AtCHIL)
分子名称: ACETATE ION, CALCIUM ION, Similarity to chalcone-flavonone isomerase
著者Noel, J.P, Louie, G.V, Bowman, M.E.
登録日2012-02-09
公開日2012-05-09
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Evolution of the chalcone-isomerase fold from fatty-acid binding to stereospecific catalysis.
Nature, 485, 2012

 

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