1HEZ
 
 | | Structure of P. magnus protein L bound to a human IgM Fab. | | 分子名称: | HEAVY CHAIN OF IG, IMIDAZOLE, KAPPA LIGHT CHAIN OF IG, ... | | 著者 | Graille, M, Stura, E.A, Housden, N.G, Bottomley, S.P, Taussig, M.J, Sutton, B.J, Gore, M.G, Charbonnier, J.B. | | 登録日 | 2000-11-27 | | 公開日 | 2001-08-10 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Complex between Peptostreptococcus Magnus Protein L and a Human Antibody Reveals Structural Convergence in the Interaction Modes of Fab Binding Modes
Structure, 9, 2001
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1MTP
 | | The X-ray crystal structure of a serpin from a thermophilic prokaryote | | 分子名称: | Serine Proteinase Inhibitor (SERPIN), Chain A, Chain B | | 著者 | Irving, J.A, Cabrita, L.D, Rossjohn, J, Pike, R.N, Bottomley, S.P, Whisstock, J.C. | | 登録日 | 2002-09-21 | | 公開日 | 2003-04-15 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The 1.5 A crystal structure of a prokaryote serpin: controlling conformational change in a heated environment
Structure, 11, 2003
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1WZ9
 | | The 2.1 A structure of a tumour suppressing serpin | | 分子名称: | Maspin precursor, SULFATE ION | | 著者 | Law, R.H, Irving, J.A, Buckle, A.M, Ruzyla, K, Buzza, M, Bashtannyk-Puhalovich, T.A, Beddoe, T.C, Kim, N, Worrall, D.M, Bottomley, S.P, Bird, P.I, Rossjohn, J, Whisstock, J.C. | | 登録日 | 2005-03-03 | | 公開日 | 2005-03-15 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix.
J.Biol.Chem., 280, 2005
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2ZNM
 | | Oxidoreductase NmDsbA3 from Neisseria meningitidis | | 分子名称: | Thiol:disulfide interchange protein DsbA | | 著者 | Vivian, J.P, Scoullar, J, Robertson, A.L, Bottomley, S.P, Horne, J, Chin, Y, Velkov, T, Wielens, J, Thompson, P.E, Piek, S, Byres, E, Beddoe, T, Wilce, M.C.J, Kahler, C, Rossjohn, J, Scanlon, M.J. | | 登録日 | 2008-04-30 | | 公開日 | 2008-08-19 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural and Biochemical Characterization of the Oxidoreductase NmDsbA3 from Neisseria meningitidis
J.Biol.Chem., 283, 2008
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1YXA
 | | Serpina3n, a murine orthologue of human antichymotrypsin | | 分子名称: | serine (or cysteine) proteinase inhibitor, clade A, member 3N | | 著者 | Horvath, A.J, Irving, J.A, Law, R.H, Rossjohn, J, Bottomley, S.P, Quinsey, N.S, Pike, R.N, Coughlin, P.B, Whisstock, J.C. | | 登録日 | 2005-02-20 | | 公開日 | 2005-09-06 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The murine orthologue of human antichymotrypsin: a structural paradigm for clade A3 serpins.
J.Biol.Chem., 280, 2005
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1D5S
 | | CRYSTAL STRUCTURE OF CLEAVED ANTITRYPSIN POLYMER | | 分子名称: | P1-ARG ANTITRYPSIN | | 著者 | Dunstone, M.A, Dai, W, Whisstock, J.C, Rossjohn, J, Pike, R.N, Feil, S.C, Le Bonneic, B.F, Parker, M.W, Bottomley, S.P. | | 登録日 | 1999-10-11 | | 公開日 | 2000-04-02 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Cleaved antitrypsin polymers at atomic resolution.
Protein Sci., 9, 2000
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1T0N
 | | Conformational switch in polymorphic H-2K molecules containing an HSV peptide | | 分子名称: | Beta-2-microglobulin, Glycoprotein B, H-2 class I histocompatibility antigen, ... | | 著者 | Webb, A.I, Borg, N.A, Dunstone, M.A, Kjer-Nielsen, L, Beddoe, T, McCluskey, J, Carbone, F.R, Bottomley, S.P, Purcell, A.W, Rossjohn, J. | | 登録日 | 2004-04-12 | | 公開日 | 2004-11-23 | | 最終更新日 | 2019-11-06 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | The structure of H-2K(b) and K(bm8) complexed to a herpes simplex virus determinant: evidence for a conformational switch that governs T cell repertoire selection and viral resistance.
J Immunol., 173, 2004
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1SYS
 | | Crystal structure of HLA, B*4403, and peptide EEPTVIKKY | | 分子名称: | Beta-2-microglobulin, Sorting nexin 5, leukocyte antigen (HLA) class I molecule | | 著者 | Zernich, D, Purcell, A.W, Macdonald, W.A, Kjer-Nielsen, L, Ely, L.K, Laham, N, Crockford, T, Mifsud, N.A, Tait, B.D, Holdsworth, R, Brooks, A.G, Bottomley, S.P, Beddoe, T, Peh, C.A, Rossjohn, J, McCluskey, J. | | 登録日 | 2004-04-01 | | 公開日 | 2004-10-19 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion
J.Exp.Med., 200, 2004
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1T0M
 | | Conformational switch in polymorphic H-2K molecules containing an HSV peptide | | 分子名称: | Beta-2-microglobulin, Glycoprotein B, H-2 class I histocompatibility antigen, ... | | 著者 | Webb, A.I, Borg, N.A, Dunstone, M.A, Kjer-Nielsen, L, Beddoe, T, McCluskey, J, Carbone, F.R, Bottomley, S.P, Purcell, A.W, Rossjohn, J. | | 登録日 | 2004-04-12 | | 公開日 | 2004-11-23 | | 最終更新日 | 2019-11-06 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The structure of H-2K(b) and K(bm8) complexed to a herpes simplex virus determinant: evidence for a conformational switch that governs T cell repertoire selection and viral resistance.
J Immunol., 173, 2004
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1SYV
 | | HLA-B*4405 complexed to the dominant self ligand EEFGRAYGF | | 分子名称: | Beta-2-microglobulin, MHC class I antigen, major histocompatibility complex, ... | | 著者 | Zernich, D, Purcell, A.W, Macdonald, W.A, Kjer-Nielsen, L, Ely, L.K, Laham, N, Crockford, T, Mifsud, N.A, Tait, B.D, Holdsworth, R, Brooks, A.G, Bottomley, S.P, Beddoe, T, Peh, C.A, Rossjohn, J, McCluskey, J. | | 登録日 | 2004-04-02 | | 公開日 | 2004-10-19 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Natural HLA class I polymorphism controls the pathway of antigen presentation and susceptibility to viral evasion
J.Exp.Med., 200, 2004
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1SNG
 | | Structure of a Thermophilic Serpin in the Native State | | 分子名称: | COG4826: Serine protease inhibitor, SULFATE ION | | 著者 | Fulton, K.F, Buckle, A.M, Cabrita, L.D, Irving, J.A, Butcher, R.E, Smith, I, Reeve, S, Lesk, A.M, Bottomley, S.P, Rossjohn, J, Whisstock, J.C. | | 登録日 | 2004-03-10 | | 公開日 | 2004-12-14 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | The high resolution crystal structure of a native thermostable serpin reveals the complex mechanism underpinning the stressed to relaxed transition.
J.Biol.Chem., 280, 2005
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2JWD
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2QP2
 | | Structure of a MACPF/perforin-like protein | | 分子名称: | CALCIUM ION, Unknown protein | | 著者 | Rosado, C.J, Buckle, A.M, Law, R.H.P, Butcher, R.E, Kan, W.T, Bird, C.H, Ung, K, Browne, K.A, Baran, K, Bashtannyk-Puhalovich, T.A, Faux, N.G, Wong, W, Porter, C.J, Pike, R.N, Ellisdon, A.M, Pearce, M.C, Bottomley, S.P, Emsley, J, Smith, A.I, Rossjohn, J, Hartland, E.L, Voskoboinik, I, Trapani, J.A, Bird, P.I, Dunstone, M.A, Whisstock, J.C. | | 登録日 | 2007-07-22 | | 公開日 | 2007-09-04 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | A common fold mediates vertebrate defense and bacterial attack
Science, 317, 2007
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2QUG
 | | Crystal structure of alpha-1-antitrypsin, crystal form A | | 分子名称: | Alpha-1-antitrypsin | | 著者 | Hansen, G, Morton, C.J, Pearce, M.C, Feil, S.C, Adams, J.J, Parker, M.W, Bottomley, S.P. | | 登録日 | 2007-08-05 | | 公開日 | 2008-08-12 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Preventing serpin aggregation: The molecular mechanism of citrate action upon antitrypsin unfolding.
Protein Sci., 17, 2008
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2VH4
 | | Structure of a loop C-sheet serpin polymer | | 分子名称: | TENGPIN | | 著者 | Zhang, Q, Law, R.H.P, Bottomley, S.P, Whisstock, J.C, Buckle, A.M. | | 登録日 | 2007-11-19 | | 公開日 | 2008-01-08 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | A Structural Basis for Loop C-Sheet Polymerization in Serpins.
J.Mol.Biol., 376, 2008
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2DUT
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3LPC
 | | Crystal structure of a subtilisin-like protease | | 分子名称: | ACETATE ION, AprB2, CALCIUM ION, ... | | 著者 | Porter, C.J, Wong, W, Whisstock, J.C, Rood, J.I, Kennan, R.M. | | 登録日 | 2010-02-05 | | 公開日 | 2010-12-08 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | The Subtilisin-Like Protease AprV2 Is Required for Virulence and Uses a Novel Disulphide-Tethered Exosite to Bind Substrates
Plos Pathog., 6, 2010
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3LPA
 | | Crystal structure of a subtilisin-like protease | | 分子名称: | Acidic extracellular subtilisin-like protease AprV2, CALCIUM ION | | 著者 | Porter, C.J, Wong, W, Whisstock, J.C, Rood, J.I, Kennan, R.M. | | 登録日 | 2010-02-05 | | 公開日 | 2010-12-08 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The Subtilisin-Like Protease AprV2 Is Required for Virulence and Uses a Novel Disulphide-Tethered Exosite to Bind Substrates
Plos Pathog., 6, 2010
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3LPD
 | | Crystal structure of a subtilisin-like protease | | 分子名称: | Acidic extracellular subtilisin-like protease AprV2, CALCIUM ION | | 著者 | Porter, C.J, Wong, W, Whisstock, J.C, Rood, J.I, Kennan, R.M. | | 登録日 | 2010-02-05 | | 公開日 | 2010-12-08 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | The Subtilisin-Like Protease AprV2 Is Required for Virulence and Uses a Novel Disulphide-Tethered Exosite to Bind Substrates
Plos Pathog., 6, 2010
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2PEE
 | | Crystal Structure of a Thermophilic Serpin, Tengpin, in the Native State | | 分子名称: | GLYCEROL, SULFATE ION, Serine protease inhibitor | | 著者 | Zhang, Q.W, Buckle, A.M, Whisstock, J.C. | | 登録日 | 2007-04-02 | | 公開日 | 2007-06-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | The N terminus of the serpin, tengpin, functions to trap the metastable native state.
Embo Rep., 8, 2007
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2PEF
 | | Crystal Structure of a Thermophilic Serpin, Tengpin, in the Latent State | | 分子名称: | Serine protease inhibitor | | 著者 | Zhang, Q.W, Buckle, A.M, Whisstock, J.C. | | 登録日 | 2007-04-03 | | 公開日 | 2007-06-19 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The N terminus of the serpin, tengpin, functions to trap the metastable native state.
Embo Rep., 8, 2007
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1XU8
 | | The 2.8 A structure of a tumour suppressing serpin | | 分子名称: | Maspin, SULFATE ION | | 著者 | Irving, J.A, Law, R.H, Ruzyla, K, Bashtannyk-Puhalovich, T.A, Kim, N, Worrall, D.M, Rossjohn, J, Whisstock, J.C. | | 登録日 | 2004-10-25 | | 公開日 | 2005-03-15 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | The high resolution crystal structure of the human tumor suppressor maspin reveals a novel conformational switch in the G-helix.
J.Biol.Chem., 280, 2005
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5CE0
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5CDX
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5CDZ
 | | Crystal structure of conserpin in the latent state | | 分子名称: | Conserpin in the latent state, GLYCEROL | | 著者 | Porebski, B.T, McGowan, S, Keleher, S, Buckle, A.M. | | 登録日 | 2015-07-06 | | 公開日 | 2016-07-20 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.449 Å) | | 主引用文献 | Smoothing a rugged protein folding landscape by sequence-based redesign.
Sci Rep, 6, 2016
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