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4BCK
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BU of 4bck by Molmil
Structure of CDK2 in complex with cyclin A and a 2-amino-4-heteroaryl- pyrimidine inhibitor
Descriptor: 3-[[5-cyano-4-[4-methyl-2-(methylamino)-1,3-thiazol-5-yl]pyrimidin-2-yl]amino]benzenesulfonamide, CYCLIN-A2, CYCLIN-DEPENDENT KINASE 2, ...
Authors:Hole, A.J, Baumli, S, Wang, S, Endicott, J.A, Noble, M.E.M.
Deposit date:2012-10-02
Release date:2013-03-06
Method:X-RAY DIFFRACTION (2.052 Å)
Cite:Comparative Structural and Functional Studies of 4-(Thiazol- 5-Yl)-2-(Phenylamino)Pyrimidine-5-Carbonitrile Cdk9 Inhibitors Suggest the Basis for Isotype Selectivity.
J.Med.Chem., 56, 2013
3FBI
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BU of 3fbi by Molmil
Structure of the Mediator submodule Med7N/31
Descriptor: Mediator of RNA polymerase II transcription subunit 31, Mediator of RNA polymerase II transcription subunit 7
Authors:Koschubs, T, Seizl, M, Lariviere, L, Kurth, F, Baumli, S, Martin, D.E, Cramer, P.
Deposit date:2008-11-19
Release date:2008-12-16
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Identification, structure, and functional requirement of the Mediator submodule Med7N/31
Embo J., 28, 2009
3FBN
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BU of 3fbn by Molmil
Structure of the Mediator submodule Med7N/31
Descriptor: Mediator of RNA polymerase II transcription subunit 31, Mediator of RNA polymerase II transcription subunit 7
Authors:Koschubs, T, Seizl, M, Lariviere, L, Kurth, F, Baumli, S, Martin, D.E, Cramer, P.
Deposit date:2008-11-19
Release date:2008-12-16
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (3.007 Å)
Cite:Identification, structure, and functional requirement of the Mediator submodule Med7N/31
Embo J., 28, 2009
2XNF
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BU of 2xnf by Molmil
The Mediator Med25 activator interaction domain: Structure and cooperative binding of VP16 subdomains
Descriptor: MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 25
Authors:Vojnic, E, Mourao, A, Seizl, M, Simon, B, Wenzeck, L, Lariviere, L, Baumli, S, Meisterernst, M, Sattler, M, Cramer, P.
Deposit date:2010-08-02
Release date:2011-03-09
Last modified:2011-07-13
Method:SOLUTION NMR
Cite:Structure and Vp16 Binding of the Mediator Med25 Activator Interaction Domain.
Nat.Struct.Mol.Biol., 18, 2011
2IVX
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BU of 2ivx by Molmil
Crystal structure of human cyclin T2 at 1.8 A resolution
Descriptor: 1,2-ETHANEDIOL, CYCLIN-T2
Authors:Debreczeni, J.E, Bullock, A.N, Fedorov, O, Savitsky, P, Berridge, G, Das, S, Pike, A.C.W, Turnbull, A, Ugochukwu, E, Papagrigoriou, E, Gorrec, F, Sundstrom, M, Edwards, A, Arrowsmith, C, Weigelt, J, von Delft, F, Knapp, S.
Deposit date:2006-06-21
Release date:2006-07-19
Last modified:2019-05-08
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation.
EMBO J., 27, 2008
2RF4
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BU of 2rf4 by Molmil
Crystal structure of the RNA Polymerase I subcomplex A14/43
Descriptor: DNA-directed RNA polymerase I subunit RPA4
Authors:Geiger, S.R, Kuhn, C.D, Cramer, P.
Deposit date:2007-09-28
Release date:2008-01-15
Last modified:2017-10-25
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Functional architecture of RNA polymerase I.
Cell(Cambridge,Mass.), 131, 2007
1TRJ
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BU of 1trj by Molmil
Homology Model of Yeast RACK1 Protein fitted into 11.7A cryo-EM map of Yeast 80S Ribosome
Descriptor: Guanine nucleotide-binding protein beta subunit-like protein, Helix 39 of 18S rRNA, Helix 40 of 18S rRNA
Authors:Sengupta, J, Nilsson, J, Gursky, R, Spahn, C.M, Nissen, P, Frank, J.
Deposit date:2004-06-21
Release date:2004-09-28
Last modified:2024-02-14
Method:ELECTRON MICROSCOPY (11.7 Å)
Cite:Identification of the versatile scaffold protein RACK1 on the eukaryotic ribosome by cryo-EM
Nat.Struct.Mol.Biol., 11, 2004
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