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FphE, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E, Oxadiazolone compound 3 bound
Descriptor:	Fluorophosphonate-binding serine hydrolase E, methyl 2-formyl-2-[3-methyl-4-(3-phenoxybenzamido)phenyl]hydrazine-1-carboxylate
Authors:	Fellner, M, Bakker, A.T, Martin, N.I, Stelt, M.
Deposit date:	2023-02-08
Release date:	2024-02-21
Method:	X-RAY DIFFRACTION (1.6 Å)
Cite:	FphE, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E, Oxadiazolone compound 3 bound To be published

E.coli DNA gyrase in complex with 217 bp substrate DNA and LEI-800
Descriptor:	DNA gyrase subunit A, DNA gyrase subunit B, MAGNESIUM ION, ...
Authors:	Ghilarov, D, Martin, N.I, van der Stelt, M.
Deposit date:	2023-10-04
Release date:	2024-06-19
Last modified:	2024-07-03
Method:	ELECTRON MICROSCOPY (2.9 Å)
Cite:	Discovery of isoquinoline sulfonamides as allosteric gyrase inhibitors with activity against fluoroquinolone-resistant bacteria. Nat.Chem., 2024

FphH, Staphylococcus aureus fluorophosphonate-binding serine hydrolases H, apo form
Descriptor:	Alpha/beta fold hydrolase, CALCIUM ION
Authors:	Fellner, M.
Deposit date:	2023-01-12
Release date:	2023-10-11
Last modified:	2023-11-22
Method:	X-RAY DIFFRACTION (1.37 Å)
Cite:	Biochemical and Cellular Characterization of the Function of Fluorophosphonate-Binding Hydrolase H (FphH) in Staphylococcus aureus Support a Role in Bacterial Stress Response. Acs Infect Dis., 9, 2023