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5ESS
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BU of 5ess by Molmil
Crystal Structure of M. tuberculosis MenD bound to Mg2+ and covalent intermediate I (a ThDP and decarboxylated 2-oxoglutarate adduct)
分子名称: 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, 4-[3-[(4-azanyl-2-methyl-pyrimidin-5-yl)methyl]-4-methyl-5-[2-[oxidanyl(phosphonooxy)phosphoryl]oxyethyl]-1,3-thiazol-3 -ium-2-yl]-4-oxidanyl-butanoic acid, ACETATE ION, ...
著者Johnston, J.M, Jirgis, E.N.M, Bashiri, G, Bulloch, E.M.M, Baker, E.N.
登録日2015-11-17
公開日2016-06-22
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Views along the Mycobacterium tuberculosis MenD Reaction Pathway Illuminate Key Aspects of Thiamin Diphosphate-Dependent Enzyme Mechanisms.
Structure, 24, 2016
5ESU
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Crystal Structure of M. tuberculosis MenD bound to Mg2+ and Covalent Intermediate II (a ThDP + de-carboxylated 2-oxoglutarate + Isochorismate adduct)
分子名称: (1~{R},2~{S},5~{S},6~{S})-2-[(1~{S})-1-[3-[(4-azanylidene-2-methyl-1~{H}-pyrimidin-5-yl)methyl]-4-methyl-5-[2-[oxidanyl (phosphonooxy)phosphoryl]oxyethyl]-1,3-thiazol-3-ium-2-yl]-1,4-bis(oxidanyl)-4-oxidanylidene-butyl]-6-oxidanyl-5-(3-oxid anyl-3-oxidanylidene-prop-1-en-2-yl)oxy-cyclohex-3-ene-1-carboxylic acid, 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase, BETA-MERCAPTOETHANOL, ...
著者Johnston, J.M, Jirgis, E.N.M, Bashiri, G, Bulloch, E.M.M, Baker, E.N.
登録日2015-11-17
公開日2016-06-22
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural Views along the Mycobacterium tuberculosis MenD Reaction Pathway Illuminate Key Aspects of Thiamin Diphosphate-Dependent Enzyme Mechanisms.
Structure, 24, 2016
1E3J
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BU of 1e3j by Molmil
Ketose reductase (sorbitol dehydrogenase) from silverleaf whitefly
分子名称: BORIC ACID, NADP(H)-DEPENDENT KETOSE REDUCTASE, PHOSPHATE ION, ...
著者Banfield, M.J, Salvucci, M.E, Baker, E.N, Smith, C.A.
登録日2000-06-19
公開日2001-02-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of Nadp(H)-Dependent Ketose Reductase from Besimia Argentifolii at 2.3 Angstrom Resolution
J.Mol.Biol., 306, 2001
1EEJ
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BU of 1eej by Molmil
CRYSTAL STRUCTURE OF THE PROTEIN DISULFIDE BOND ISOMERASE, DSBC, FROM ESCHERICHIA COLI
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, THIOL:DISULFIDE INTERCHANGE PROTEIN
著者McCarthy, A.A, Haebel, P.W, Torronen, A, Rybin, V, Baker, E.N, Metcalf, P.
登録日2000-01-31
公開日2000-08-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of the protein disulfide bond isomerase, DsbC, from Escherichia coli.
Nat.Struct.Biol., 7, 2000
1EH3
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BU of 1eh3 by Molmil
R210K N-TERMINAL LOBE HUMAN LACTOFERRIN
分子名称: CARBONATE ION, FE (III) ION, LACTOFERRIN
著者Peterson, N.A, Anderson, B.F, Jameson, G.B, Tweedie, J.W, Baker, E.N.
登録日2000-02-18
公開日2000-03-01
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure and iron-binding properties of the R210K mutant of the N-lobe of human lactoferrin: implications for iron release from transferrins.
Biochemistry, 39, 2000
3KGF
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BU of 3kgf by Molmil
The structure of 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis complexed with phenylalanine and tryptophan
分子名称: CHLORIDE ION, GLYCEROL, MANGANESE (II) ION, ...
著者Parker, E.J, Jameson, G.B, Jiao, W, Webby, C.J, Baker, E.N, Baker, H.M, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2009-10-29
公開日2010-07-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis
J.Biol.Chem., 285, 2010
3NV8
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BU of 3nv8 by Molmil
The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase in complex with phosphoenol pyruvate and manganese (thesit-free)
分子名称: CHLORIDE ION, GLYCEROL, MANGANESE (II) ION, ...
著者Parker, E.J, Jameson, G.B, Jiao, W, Hutton, R.H, Webby, C.J, Baker, E.N, Baker, H.M.
登録日2010-07-08
公開日2010-07-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Synergistic allostery, a sophisticated regulatory network for the control of aromatic amino acid biosynthesis in Mycobacterium tuberculosis
J.Biol.Chem., 285, 2010
1LCT
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BU of 1lct by Molmil
STRUCTURE OF THE RECOMBINANT N-TERMINAL LOBE OF HUMAN LACTOFERRIN AT 2.0 ANGSTROMS RESOLUTION
分子名称: CARBONATE ION, FE (III) ION, LACTOFERRIN
著者Day, C.L, Anderson, B.F, Baker, E.N.
登録日1993-06-19
公開日1993-10-31
最終更新日2017-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the recombinant N-terminal lobe of human lactoferrin at 2.0 A resolution.
J.Mol.Biol., 232, 1993
6BBT
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BU of 6bbt by Molmil
Structure of the major pilin protein (T-13) from Streptococcus pyogenes serotype GAS131465
分子名称: CALCIUM ION, CHLORIDE ION, GLYCEROL, ...
著者Young, P.G, Baker, E.N, Moreland, N.J.
登録日2017-10-19
公開日2018-10-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Group AStreptococcusT Antigens Have a Highly Conserved Structure Concealed under a Heterogeneous Surface That Has Implications for Vaccine Design.
Infect.Immun., 87, 2019
6BBW
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BU of 6bbw by Molmil
Structure of the major pilin protein (T3.2) from Streptococcus pyogenes serotype GAS13637
分子名称: CALCIUM ION, Major pilin backbone protein T-antigen, T3.2.
著者Young, P.G, Baker, E.N, Moreland, N.J.
登録日2017-10-19
公開日2018-10-24
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Group AStreptococcusT Antigens Have a Highly Conserved Structure Concealed under a Heterogeneous Surface That Has Implications for Vaccine Design.
Infect.Immun., 87, 2019
6BWH
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BU of 6bwh by Molmil
Crystal structure of Mycoibacterium tuberculosis Rv2983 in complex with PEP
分子名称: 2-phospho-L-lactate guanylyltransferase, MAGNESIUM ION, PHOSPHOENOLPYRUVATE
著者Bashiri, G, Jirgis, E.N.M, Baker, E.N.
登録日2017-12-15
公開日2018-12-19
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献A revised biosynthetic pathway for the cofactor F420in prokaryotes.
Nat Commun, 10, 2019
6BWG
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BU of 6bwg by Molmil
Crystal structure of native Rv2983 from Mycobacterium tuberculosis
分子名称: 2-phospho-L-lactate guanylyltransferase
著者Bashiri, G, Jirgis, E.N.M, Baker, E.N.
登録日2017-12-15
公開日2018-12-19
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献A revised biosynthetic pathway for the cofactor F420in prokaryotes.
Nat Commun, 10, 2019
2RDG
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BU of 2rdg by Molmil
Crystal structure of Staphylococcal Superantigen-Like protein 11 in complex with Sialyl Lewis X
分子名称: CITRIC ACID, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-alpha-D-glucopyranose, POTASSIUM ION, ...
著者Chung, M.C, Wines, B.D, Baker, H, Langley, R.J, Baker, E.N, Fraser, J.D.
登録日2007-09-24
公開日2007-12-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The crystal structure of staphylococcal superantigen-like protein 11 in complex with sialyl Lewis X reveals the mechanism for cell binding and immune inhibition
Mol.Microbiol., 66, 2007
2RDH
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BU of 2rdh by Molmil
Crystal structure of Staphylococcal Superantigen-Like protein 11
分子名称: PHOSPHATE ION, SODIUM ION, Superantigen-like protein 11
著者Chung, M.C, Wines, B.D, Baker, H, Langley, R.J, Baker, E.N, Fraser, J.D.
登録日2007-09-24
公開日2007-12-18
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献The crystal structure of staphylococcal superantigen-like protein 11 in complex with sialyl Lewis X reveals the mechanism for cell binding and immune inhibition
Mol.Microbiol., 66, 2007
2B7O
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BU of 2b7o by Molmil
The Structure of 3-Deoxy-D-Arabino-Heptulosonate 7-Phosphate Synthase from Mycobacterium tuberculosis
分子名称: 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG, MANGANESE (II) ION, O-DODECANYL OCTAETHYLENE GLYCOL, ...
著者Webby, C.J, Baker, H.M, Lott, J.S, Baker, E.N, Parker, E.J, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2005-10-05
公開日2005-10-18
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The structure of 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase from Mycobacterium tuberculosis reveals a common catalytic scaffold and ancestry for type I and type II enzymes
J.Mol.Biol., 354, 2005
2BLG
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BU of 2blg by Molmil
STRUCTURAL BASIS OF THE TANFORD TRANSITION OF BOVINE BETA-LACTOGLOBULIN FROM CRYSTAL STRUCTURES AT THREE PH VALUES; PH 8.2
分子名称: BETA-LACTOGLOBULIN
著者Qin, B.Y, Bewley, M.C, Creamer, L.K, Baker, H.M, Baker, E.N, Jameson, G.B.
登録日1998-08-29
公開日1999-01-27
最終更新日2021-07-28
実験手法X-RAY DIFFRACTION (2.46 Å)
主引用文献Structural basis of the Tanford transition of bovine beta-lactoglobulin.
Biochemistry, 37, 1998
2Z8L
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BU of 2z8l by Molmil
Crystal Structure of the Staphylococcal superantigen-like protein SSL5 at pH 4.6 complexed with sialyl Lewis X
分子名称: Exotoxin 3, GLYCEROL, N-acetyl-alpha-neuraminic acid-(2-3)-beta-D-galactopyranose-(1-4)-[alpha-L-fucopyranose-(1-3)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Baker, H.M, Basu, I, Chung, M.C, Caradoc Davies, T, Fraser, J.D, Baker, E.N.
登録日2007-09-06
公開日2007-11-27
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Crystal structures of the staphylococcal toxin SSL5 in complex with sialyl Lewis X reveal a conserved binding site that shares common features with viral and bacterial sialic acid binding proteins
J.Mol.Biol., 374, 2007
2F00
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Escherichia coli MurC
分子名称: MAGNESIUM ION, UDP-N-acetylmuramate--L-alanine ligase
著者Deva, T, Baker, E.N, Squire, C.J, Smith, C.A.
登録日2005-11-10
公開日2006-10-24
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure of Escherichia coliUDP-N-acetylmuramoyl:L-alanine ligase (MurC).
Acta Crystallogr.,Sect.D, 62, 2006
3BLG
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STRUCTURAL BASIS OF THE TANFORD TRANSITION OF BOVINE BETA-LACTOGLOBULIN FROM CRYSTAL STRUCTURES AT THREE PH VALUES; PH 6.2
分子名称: BETA-LACTOGLOBULIN
著者Qin, B.Y, Bewley, M.C, Creamer, L.K, Baker, H.M, Baker, E.N, Jameson, G.B.
登録日1998-08-29
公開日1999-01-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献Structural basis of the Tanford transition of bovine beta-lactoglobulin.
Biochemistry, 37, 1998
1JC5
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BU of 1jc5 by Molmil
Crystal Structure of Native Methylmalonyl-CoA Epimerase
分子名称: Methylmalonyl-CoA Epimerase, SULFATE ION
著者Mc Carthy, A.A, Baker, H.M, Shewry, S.C, Patchett, M.L, Baker, E.N.
登録日2001-06-07
公開日2001-07-11
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of methylmalonyl-coenzyme A epimerase from P. shermanii: a novel enzymatic function on an ancient metal binding scaffold.
Structure, 9, 2001
4XOO
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FMN complex of coenzyme F420:L-glutamate ligase (FbiB) from Mycobacterium tuberculosis (C-terminal domain)
分子名称: Coenzyme F420:L-glutamate ligase, FLAVIN MONONUCLEOTIDE
著者Rehan, A.M, Bashiri, G, Baker, H.M, Baker, E.N, Squire, C.J.
登録日2015-01-16
公開日2016-02-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Elongation of the Poly-gamma-glutamate Tail of F420 Requires Both Domains of the F420: gamma-Glutamyl Ligase (FbiB) of Mycobacterium tuberculosis.
J.Biol.Chem., 291, 2016
4XOQ
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BU of 4xoq by Molmil
F420 complex of coenzyme F420:L-glutamate ligase (FbiB) from Mycobacterium tuberculosis (C-terminal domain)
分子名称: COENZYME F420, Coenzyme F420:L-glutamate ligase, SULFATE ION
著者Rehan, A.M, Bashiri, G, Baker, H.M, Baker, E.N, Squire, C.J.
登録日2015-01-16
公開日2016-02-17
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Elongation of the Poly-gamma-glutamate Tail of F420 Requires Both Domains of the F420: gamma-Glutamyl Ligase (FbiB) of Mycobacterium tuberculosis.
J.Biol.Chem., 291, 2016
4XOM
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Coenzyme F420:L-glutamate ligase (FbiB) from Mycobacterium tuberculosis (C-terminal domain).
分子名称: Coenzyme F420:L-glutamate ligase, SULFATE ION
著者Rehan, A.M, Bashiri, G, Baker, H.M, Baker, E.N, Squire, C.J.
登録日2015-01-16
公開日2016-02-17
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Elongation of the Poly-gamma-glutamate Tail of F420 Requires Both Domains of the F420: gamma-Glutamyl Ligase (FbiB) of Mycobacterium tuberculosis.
J.Biol.Chem., 291, 2016
2FYF
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Structure of a putative phosphoserine aminotransferase from Mycobacterium Tuberculosis
分子名称: GLYCEROL, PYRIDOXAL-5'-PHOSPHATE, SULFATE ION, ...
著者Coulibaly, F, Lassalle, E, Baker, E.N, Mycobacterium Tuberculosis Structural Proteomics Project (XMTB)
登録日2006-02-07
公開日2007-01-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of phosphoserine aminotransferase from Mycobacterium tuberculosis.
Acta Crystallogr.,Sect.D, 68, 2012
1VFE
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HUMAN LACTOFERRIN, N-TERMINAL LOBE MUTANT WITH ARG 121 REPLACED BY SER (R121S)
分子名称: CARBONATE ION, FE (III) ION, HUMAN LACTOFERRIN
著者Faber, H.R, Day, C.L, Baker, E.N.
登録日1996-10-01
公開日1997-04-01
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Mutation of arginine 121 in lactoferrin destabilizes iron binding by disruption of anion binding: crystal structures of R121S and R121E mutants.
Biochemistry, 35, 1996

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