8EO2
 
 | | Lufaxin a bifunctional inhibitor of complement and coagulation | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, BROMIDE ION, ... | | 著者 | Andersen, J.F, Strayer, E.C. | | 登録日 | 2022-10-01 | | 公開日 | 2023-08-09 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.31 Å) | | 主引用文献 | A bispecific inhibitor of complement and coagulation blocks activation in complementopathy models via a novel mechanism.
Blood, 141, 2023
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8ENU
 | | Structure of the C3bB proconvertase in complex with lufaxin | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Complement C3 beta chain, Complement C3b alpha' chain, ... | | 著者 | Andersen, J.F, Lei, H. | | 登録日 | 2022-09-30 | | 公開日 | 2023-08-09 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | | 主引用文献 | A bispecific inhibitor of complement and coagulation blocks activation in complementopathy models via a novel mechanism.
Blood, 141, 2023
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8EOK
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1AIU
 | | HUMAN THIOREDOXIN (D60N MUTANT, REDUCED FORM) | | 分子名称: | THIOREDOXIN | | 著者 | Andersen, J.F, Gasdaska, J.R, Sanders, D.A.R, Weichsel, A, Powis, G, Montfort, W.R. | | 登録日 | 1997-04-25 | | 公開日 | 1997-07-07 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Human thioredoxin homodimers: regulation by pH, role of aspartate 60, and crystal structure of the aspartate 60 --> asparagine mutant.
Biochemistry, 36, 1997
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1EUO
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1NP4
 | | CRYSTAL STRUCTURE OF NITROPHORIN 4 FROM RHODNIUS PROLIXUS | | 分子名称: | AMMONIA, PROTEIN (NITROPHORIN 4), PROTOPORPHYRIN IX CONTAINING FE | | 著者 | Andersen, J.F, Weichsel, A, Champagne, D.E, Balfour, C.A, Montfort, W.R. | | 登録日 | 1998-07-29 | | 公開日 | 1998-08-05 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | The crystal structure of nitrophorin 4 at 1.5 A resolution: transport of nitric oxide by a lipocalin-based heme protein.
Structure, 6, 1998
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6MT7
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6MTF
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6XKE
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6XL7
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6XMB
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7TVY
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7TVC
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7TX8
 | | Long form D7 protein from Anopheles darlingi with U46619 and serotonin bound | | 分子名称: | (5Z)-7-{(1R,4S,5S,6R)-6-[(1E,3S)-3-hydroxyoct-1-en-1-yl]-2-oxabicyclo[2.2.1]hept-5-yl}hept-5-enoic acid, Long form D7 salivary protein, SEROTONIN | | 著者 | Andersen, J.F, Alvarenga, P.H. | | 登録日 | 2022-02-08 | | 公開日 | 2022-06-01 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | | 主引用文献 | Functional aspects of evolution in a cluster of salivary protein genes from mosquitoes.
Insect Biochem.Mol.Biol., 146, 2022
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4TPV
 | | Crystal Structure of Hookworm Platelet Inhibitor | | 分子名称: | GLYCEROL, Platelet inhibitor | | 著者 | Andersen, J.F, Ma, D, Francischetti, I. | | 登録日 | 2014-06-09 | | 公開日 | 2015-04-22 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | The structure of hookworm platelet inhibitor (HPI), a CAP superfamily member from Ancylostoma caninum.
Acta Crystallogr.,Sect.F, 71, 2015
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5H9N
 | | Crystal structure of LTBP1 Y114A mutant in complex with leukotriene C4 | | 分子名称: | (5~{S},6~{R},7~{E},9~{E},11~{Z},14~{Z})-6-[(2~{R})-2-[[(4~{S})-4-azanyl-5-oxidanyl-5-oxidanylidene-pentanoyl]amino]-3-(2-hydroxy-2-oxoethylamino)-3-oxidanylidene-propyl]sulfanyl-5-oxidanyl-icosa-7,9,11,14-tetraenoic acid, Lipocalin AI-4 | | 著者 | Andersen, J.F. | | 登録日 | 2015-12-28 | | 公開日 | 2016-05-11 | | 最終更新日 | 2017-05-24 | | 実験手法 | X-RAY DIFFRACTION (1.28 Å) | | 主引用文献 | Structure and Ligand-Binding Mechanism of a Cysteinyl Leukotriene-Binding Protein from a Blood-Feeding Disease Vector.
Acs Chem.Biol., 11, 2016
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5H9L
 | | Crystal Structure of LTBP1 in complex with cleaved Leukotriene C4 | | 分子名称: | (5S,7E,9E,11Z,14Z)-5-hydroxyicosa-7,9,11,14-tetraenoic acid, GLUTATHIONE, Lipocalin AI-4 | | 著者 | Andersen, J.F. | | 登録日 | 2015-12-28 | | 公開日 | 2016-05-11 | | 最終更新日 | 2016-07-27 | | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | | 主引用文献 | Structure and Ligand-Binding Mechanism of a Cysteinyl Leukotriene-Binding Protein from a Blood-Feeding Disease Vector.
Acs Chem.Biol., 11, 2016
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5HA0
 | | Crystal structure of the LTBP1 leukotriene d4 complex | | 分子名称: | (5~{S},6~{R},7~{E},9~{E},11~{Z},14~{Z})-6-[(2~{R})-2-azanyl-3-(2-hydroxy-2-oxoethylamino)-3-oxidanylidene-propyl]sulfanyl-5-oxidanyl-icosa-7,9,11,14-tetraenoic acid, Lipocalin AI-4 | | 著者 | Andersen, J.F. | | 登録日 | 2015-12-29 | | 公開日 | 2016-05-11 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.441 Å) | | 主引用文献 | Structure and Ligand-Binding Mechanism of a Cysteinyl Leukotriene-Binding Protein from a Blood-Feeding Disease Vector.
Acs Chem.Biol., 11, 2016
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5HAE
 | | Crystal structure of LTBP1 LTC4 complex collected on an in-house source | | 分子名称: | (5S,7E,9E,11Z,14Z)-5-hydroxyicosa-7,9,11,14-tetraenoic acid, GLUTATHIONE, Lipocalin AI-4 | | 著者 | Andersen, J.F. | | 登録日 | 2015-12-30 | | 公開日 | 2016-05-11 | | 最終更新日 | 2018-03-07 | | 実験手法 | X-RAY DIFFRACTION (2.002 Å) | | 主引用文献 | Structure and Ligand-Binding Mechanism of a Cysteinyl Leukotriene-Binding Protein from a Blood-Feeding Disease Vector.
Acs Chem.Biol., 11, 2016
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5H9K
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5K6D
 | | Structure of FS50 an antagonist of NaV1.5 | | 分子名称: | Putative secreted salivary protein | | 著者 | Andersen, J.F, Xu, X. | | 登録日 | 2016-05-24 | | 公開日 | 2016-11-23 | | 実験手法 | X-RAY DIFFRACTION (1.139 Å) | | 主引用文献 | Structure and Function of FS50, a salivary protein from the flea Xenopsylla cheopis that blocks the sodium channel NaV1.5.
Sci Rep, 6, 2016
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5V13
 | | Mosquito juvenile hormone-binding protein | | 分子名称: | AAEL008620-PA odorant-binding protein, methyl (2E,6E)-9-[(2R)-3,3-dimethyloxiran-2-yl]-3,7-dimethylnona-2,6-dienoate | | 著者 | Andersen, J.F, Kim, I.H. | | 登録日 | 2017-03-01 | | 公開日 | 2017-08-09 | | 最終更新日 | 2017-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | A mosquito hemolymph odorant-binding protein family member specifically binds juvenile hormone.
J. Biol. Chem., 292, 2017
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3U3N
 | | Crystal structure of tablysin-15 | | 分子名称: | CITRIC ACID, PALMITIC ACID, PRASEODYMIUM ION, ... | | 著者 | Andersen, J.F. | | 登録日 | 2011-10-06 | | 公開日 | 2012-02-15 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.651 Å) | | 主引用文献 | Structure of protein having inhibitory disintegrin and leukotriene scavenging functions contained in single domain.
J.Biol.Chem., 287, 2012
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3U3L
 | | Crystal structure of the selenomethionine derivative of tablysin-15 | | 分子名称: | CITRIC ACID, PALMITIC ACID, PRASEODYMIUM ION, ... | | 著者 | Andersen, J.F, Xu, X, Ribeiro, J.M. | | 登録日 | 2011-10-06 | | 公開日 | 2012-02-15 | | 最終更新日 | 2017-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.57 Å) | | 主引用文献 | Structure of protein having inhibitory disintegrin and leukotriene scavenging functions contained in single domain.
J.Biol.Chem., 287, 2012
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3U3U
 | | Crystal structure of the tablysin-15-leukotriene E4 complex | | 分子名称: | (5S,7E,9E,11Z,14Z)-5-hydroxyicosa-7,9,11,14-tetraenoic acid, CITRIC ACID, PRASEODYMIUM ION, ... | | 著者 | Andersen, J.F. | | 登録日 | 2011-10-06 | | 公開日 | 2012-02-15 | | 最終更新日 | 2015-01-28 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of protein having inhibitory disintegrin and leukotriene scavenging functions contained in single domain.
J.Biol.Chem., 287, 2012
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