6IFX
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6IFS
| KsgA from Bacillus subtilis 168 | Descriptor: | Ribosomal RNA small subunit methyltransferase A | Authors: | Bhujbalrao, R, Anand, R. | Deposit date: | 2018-09-21 | Release date: | 2019-01-30 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (2.27 Å) | Cite: | Deciphering Determinants in Ribosomal Methyltransferases That Confer Antimicrobial Resistance. J. Am. Chem. Soc., 141, 2019
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3CO7
| Crystal Structure of FoxO1 DBD Bound to DBE2 DNA | Descriptor: | DNA (5'-D(*DCP*DAP*DAP*DAP*DAP*DTP*DGP*DTP*DAP*DAP*DAP*DCP*DAP*DAP*DGP*DA)-3'), DNA (5'-D(*DTP*DCP*DTP*DTP*DGP*DTP*DTP*DTP*DAP*DCP*DAP*DTP*DTP*DTP*DTP*DG)-3'), Forkhead box protein O1 | Authors: | Brent, M.M, Anand, R, Marmorstein, R. | Deposit date: | 2008-03-27 | Release date: | 2008-09-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.91 Å) | Cite: | Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification. Structure, 16, 2008
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3CO6
| Crystal Structure of FoxO1 DBD Bound to DBE1 DNA | Descriptor: | CALCIUM ION, CHLORIDE ION, DNA (5'-D(*DCP*DAP*DAP*DGP*DGP*DTP*DAP*DAP*DAP*DCP*DAP*DAP*DAP*DCP*DCP*DA)-3'), ... | Authors: | Brent, M.M, Anand, R, Marmorstein, R. | Deposit date: | 2008-03-27 | Release date: | 2008-09-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification. Structure, 16, 2008
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3COA
| Crystal Structure of FoxO1 DBD Bound to IRE DNA | Descriptor: | CALCIUM ION, DNA (5'-D(*DCP*DAP*DAP*DGP*DCP*DAP*DAP*DAP*DAP*DCP*DAP*DAP*DAP*DCP*DCP*DA)-3'), DNA (5'-D(*DTP*DGP*DGP*DTP*DTP*DTP*DGP*DTP*DTP*DTP*DTP*DGP*DCP*DTP*DTP*DG)-3'), ... | Authors: | Brent, M.M, Anand, R, Marmorstein, R. | Deposit date: | 2008-03-27 | Release date: | 2008-09-16 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structural Basis for DNA Recognition by FoxO1 and Its Regulation by Posttranslational Modification. Structure, 16, 2008
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4R7G
| Determination of the formylglycinamide ribonucleotide amidotransferase ammonia pathway by combining 3D-RISM theory with experiment | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Phosphoribosylformylglycinamidine synthase, ... | Authors: | Tanwar, A.S, Sindhikara, D.J, Hirata, F, Anand, R. | Deposit date: | 2014-08-27 | Release date: | 2015-01-21 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Determination of the formylglycinamide ribonucleotide amidotransferase ammonia pathway by combining 3D-RISM theory with experiment. Acs Chem.Biol., 10, 2015
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7C3T
| Crystal structure of NE0047 (N66Q) mutant in complex with 8-azaguanine | Descriptor: | 5-AMINO-1H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-OL, Cytidine and deoxycytidylate deaminase zinc-binding region, ZINC ION | Authors: | Gaded, V, Bitra, A, Singh, J, Anand, R. | Deposit date: | 2020-05-14 | Release date: | 2021-05-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.07 Å) | Cite: | Structure guided mutagenesis reveals the substrate determinants of guanine deaminase. J.Struct.Biol., 213, 2021
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7C3U
| Crystal structure of NE0047 (N66A) mutant in complex with 8-azaguanine | Descriptor: | 1,2-ETHANEDIOL, 5-AMINO-1H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-OL, Cytidine and deoxycytidylate deaminase zinc-binding region, ... | Authors: | Gaded, V, Bitra, A, Singh, J, Anand, R. | Deposit date: | 2020-05-14 | Release date: | 2021-05-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Structure guided mutagenesis reveals the substrate determinants of guanine deaminase. J.Struct.Biol., 213, 2021
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7C3S
| Crystal structure of NE0047 (E143D) mutant in complex with 8-azaguanine | Descriptor: | 1,2-ETHANEDIOL, 5-AMINO-1H-[1,2,3]TRIAZOLO[4,5-D]PYRIMIDIN-7-OL, Cytidine and deoxycytidylate deaminase zinc-binding region, ... | Authors: | Gaded, V, Bitra, A, Singh, J, Anand, R. | Deposit date: | 2020-05-14 | Release date: | 2021-05-26 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Structure guided mutagenesis reveals the substrate determinants of guanine deaminase. J.Struct.Biol., 213, 2021
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7CPH
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7EDZ
| Crystal Structure of human PPCS in complex with P-HoPan and AMPPNP | Descriptor: | 4-[[(2R)-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]butanoic acid, GLYCEROL, MAGNESIUM ION, ... | Authors: | Sharma, N, Mostert, K.J, Strauss, E, Anand, R. | Deposit date: | 2021-03-17 | Release date: | 2021-11-24 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | The Coenzyme A Level Modulator Hopantenate (HoPan) Inhibits Phosphopantotenoylcysteine Synthetase Activity. Acs Chem.Biol., 16, 2021
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6JT7
| Crystal structure of 452-453_deletion mutant of FGAM Synthetase | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, ... | Authors: | Sharma, N, Ahalawat, N, Sandhu, P, Mondal, J, Anand, R. | Deposit date: | 2019-04-10 | Release date: | 2020-03-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Role of allosteric switches and adaptor domains in long-distance cross-talk and transient tunnel formation. Sci Adv, 6, 2020
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6JT8
| Crystal structure of 450-451_deletion mutant of FGAM Synthetase | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | Authors: | Sharma, N, Ahalawat, N, Sandhu, P, Mondal, J, Anand, R. | Deposit date: | 2019-04-10 | Release date: | 2020-03-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Role of allosteric switches and adaptor domains in long-distance cross-talk and transient tunnel formation. Sci Adv, 6, 2020
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6LYM
| Crystal structure of D657A mutant of formylglycinamidine synthetase | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | Authors: | Sharma, N, Tanwar, A.S, Anand, R. | Deposit date: | 2020-02-14 | Release date: | 2021-02-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.46 Å) | Cite: | Mechanism of Coordinated Gating and Signal Transduction in Purine Biosynthetic Enzyme Formylglycinamidine Synthetase. Acs Catalysis, 12, 2022
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6LYO
| Crystal Structure of H296A mutant of Formylglycinamidine Synthetase | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | Authors: | Sharma, N, Tanwar, A.S, Anand, R. | Deposit date: | 2020-02-15 | Release date: | 2021-02-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | Mechanism of Coordinated Gating and Signal Transduction in Purine Biosynthetic Enzyme Formylglycinamidine Synthetase. Acs Catalysis, 12, 2022
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6LYK
| Crystal Structure of R1263A mutant of Formylglycinamidine Synthetase | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLUTAMINE, ... | Authors: | Sharma, N, Tanwar, A.S, Anand, R. | Deposit date: | 2020-02-14 | Release date: | 2021-02-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Mechanism of Coordinated Gating and Signal Transduction in Purine Biosynthetic Enzyme Formylglycinamidine Synthetase. Acs Catalysis, 12, 2022
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6LYL
| Crystal structure of S1052D mutant of Formylglycinamidine synthetase | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLYCEROL, ... | Authors: | Sharma, N, Tanwar, A.S, Anand, R. | Deposit date: | 2020-02-14 | Release date: | 2021-02-17 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Mechanism of Coordinated Gating and Signal Transduction in Purine Biosynthetic Enzyme Formylglycinamidine Synthetase. Acs Catalysis, 12, 2022
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7V2P
| T.thermophilus 30S ribosome with KsgA, class K5 | Descriptor: | 16s ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Raina, R, Singh, J, Anand, R, Vinothkumar, K.R. | Deposit date: | 2021-08-09 | Release date: | 2022-04-06 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Decoding the Mechanism of Specific RNA Targeting by Ribosomal Methyltransferases. Acs Chem.Biol., 17, 2022
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7V2N
| T.thermophilus 30S ribosome with KsgA, class K2 | Descriptor: | 16s ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Raina, R, Singh, J, Anand, R, Vinothkumar, K.R. | Deposit date: | 2021-08-09 | Release date: | 2022-04-06 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Decoding the Mechanism of Specific RNA Targeting by Ribosomal Methyltransferases. Acs Chem.Biol., 17, 2022
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7V2Q
| T.thermophilus 30S ribosome with KsgA, class K6 | Descriptor: | 16s ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Raina, R, Singh, J, Anand, R, Vinothkumar, K.R. | Deposit date: | 2021-08-09 | Release date: | 2022-04-06 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (3.24 Å) | Cite: | Decoding the Mechanism of Specific RNA Targeting by Ribosomal Methyltransferases. Acs Chem.Biol., 17, 2022
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7V2L
| T.thermophilus 30S ribosome with KsgA, class K1k2 | Descriptor: | 16s ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Raina, R, Singh, J, Anand, R, Vinothkumar, K.R. | Deposit date: | 2021-08-09 | Release date: | 2022-04-06 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Decoding the Mechanism of Specific RNA Targeting by Ribosomal Methyltransferases. Acs Chem.Biol., 17, 2022
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7V2M
| T.thermophilus 30S ribosome with KsgA, class K1k4 | Descriptor: | 16s ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Raina, R, Singh, J, Anand, R, Vinothkumar, K.R. | Deposit date: | 2021-08-09 | Release date: | 2022-04-06 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Decoding the Mechanism of Specific RNA Targeting by Ribosomal Methyltransferases. Acs Chem.Biol., 17, 2022
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7V2O
| T.thermophilus 30S ribosome with KsgA, class K4 | Descriptor: | 16s ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | Authors: | Raina, R, Singh, J, Anand, R, Vinothkumar, K.R. | Deposit date: | 2021-08-09 | Release date: | 2022-04-06 | Last modified: | 2022-04-27 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Decoding the Mechanism of Specific RNA Targeting by Ribosomal Methyltransferases. Acs Chem.Biol., 17, 2022
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6JT9
| Crystal Structure of D464A mutant of FGAM Synthetase | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, CHLORIDE ION, GLYCEROL, ... | Authors: | Sharma, N, Ahalawat, N, Sandhu, P, Mondal, J, Anand, R. | Deposit date: | 2019-04-10 | Release date: | 2020-03-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Role of allosteric switches and adaptor domains in long-distance cross-talk and transient tunnel formation. Sci Adv, 6, 2020
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6JTA
| Crystal Structure of D464A L465A mutant of FGAM Synthetase | Descriptor: | 1,2-ETHANEDIOL, ADENOSINE-5'-DIPHOSPHATE, GLUTAMINE, ... | Authors: | Sharma, N, Ahalawat, N, Sandhu, P, Mondal, J, Anand, R. | Deposit date: | 2019-04-10 | Release date: | 2020-03-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Role of allosteric switches and adaptor domains in long-distance cross-talk and transient tunnel formation. Sci Adv, 6, 2020
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