3DAZ
| Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties | Descriptor: | Carbonic anhydrase 2, N-(3-methyl-5-sulfamoyl-1,3,4-thiadiazol-2(3H)-ylidene)acetamide, ZINC ION | Authors: | Genis, C, Sippel, K.H, Case, N, Govindasamy, L, Agbandje-Mckenna, M, Mckenna, R. | Deposit date: | 2008-05-30 | Release date: | 2009-03-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties Biochemistry, 48, 2009
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3DCC
| Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties | Descriptor: | 5-(2-chlorophenyl)-1,3,4-thiadiazole-2-sulfonamide, Carbonic anhydrase 2, ZINC ION | Authors: | Genis, C, Sippel, K.H, Case, N, Govindasamy, L, Agbandje-Mckenna, M, Mckenna, R. | Deposit date: | 2008-06-03 | Release date: | 2009-03-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties Biochemistry, 48, 2009
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3D8W
| Use of a carbonic Anhydrase II, IX Active-site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties | Descriptor: | 5-[(phenylsulfonyl)amino]-1,3,4-thiadiazole-2-sulfonamide, Carbonic anhydrase II, ZINC ION | Authors: | Genis, C, Sippel, K.H, Case, N, Govindasamy, L, Agbandje-Mckenna, M, Mckenna, R. | Deposit date: | 2008-05-26 | Release date: | 2009-03-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties Biochemistry, 48, 2009
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3DBU
| Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties | Descriptor: | 5-[(phenylsulfonyl)amino]-1,3,4-thiadiazole-2-sulfonamide, Carbonic anhydrase 2, ZINC ION | Authors: | Genis, C, Sippel, K.H, Case, N, Govindasamy, L, Agbandje-Mckenna, M, Mckenna, R. | Deposit date: | 2008-06-02 | Release date: | 2009-03-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties Biochemistry, 48, 2009
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3DD0
| Use of Carbonic Anhydrase II, IX Active-Site Mimic, for the Purpose of Screening Inhibitors for Possible Anti-Cancer Properties | Descriptor: | 6-ethoxy-1,3-benzothiazole-2-sulfonamide, Carbonic anhydrase 2, ZINC ION | Authors: | Genis, C, Sippel, K.H, Case, N, Govindasamy, L, Agbandje-Mckenna, M, Mckenna, R. | Deposit date: | 2008-06-04 | Release date: | 2009-03-03 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.48 Å) | Cite: | Design of a carbonic anhydrase IX active-site mimic to screen inhibitors for possible anticancer properties Biochemistry, 48, 2009
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8TXO
| E. coli DNA-directed RNA polymerase transcription elongation complex bound to the unnatural dZ-PTP base pair in the active site | Descriptor: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | Authors: | Aiyer, S, Shan, Z, Oh, J, Wang, D, Tan, Y.Z, Lyumkis, D. | Deposit date: | 2023-08-23 | Release date: | 2024-01-24 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Overcoming resolution attenuation during tilted cryo-EM data collection. Nat Commun, 15, 2024
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7U97
| SAAV pH 4.0 capsid structure | Descriptor: | Capsid protein | Authors: | Mietzsch, M, McKenna, R. | Deposit date: | 2022-03-10 | Release date: | 2022-04-13 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.66 Å) | Cite: | Characterization of the Serpentine Adeno-Associated Virus (SAAV) Capsid Structure: Receptor Interactions and Antigenicity. J.Virol., 96, 2022
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7U95
| SAAV pH 6.0 capsid structure | Descriptor: | Capsid protein | Authors: | Mietzsch, M, McKenna, R. | Deposit date: | 2022-03-10 | Release date: | 2022-04-13 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.73 Å) | Cite: | Characterization of the Serpentine Adeno-Associated Virus (SAAV) Capsid Structure: Receptor Interactions and Antigenicity. J.Virol., 96, 2022
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7U96
| SAAV pH 5.5 capsid structure | Descriptor: | Capsid protein | Authors: | Mietzsch, M, McKenna, R. | Deposit date: | 2022-03-10 | Release date: | 2022-04-13 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (2.14 Å) | Cite: | Characterization of the Serpentine Adeno-Associated Virus (SAAV) Capsid Structure: Receptor Interactions and Antigenicity. J.Virol., 96, 2022
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7U94
| SAAV pH 7.4 capsid structure | Descriptor: | Capsid protein | Authors: | Mietzsch, M, McKenna, R. | Deposit date: | 2022-03-10 | Release date: | 2022-04-13 | Last modified: | 2024-02-14 | Method: | ELECTRON MICROSCOPY (3.25 Å) | Cite: | Characterization of the Serpentine Adeno-Associated Virus (SAAV) Capsid Structure: Receptor Interactions and Antigenicity. J.Virol., 96, 2022
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4XZ5
| Structure of the thermostable alpha-Carbonic Anydrase from Thiomicrospira crunogena XCL-2 gammaproteobacterium | Descriptor: | BICARBONATE ION, Carbonic anhydrase, alpha family, ... | Authors: | Mahon, B.P, Diaz-Torres, N.A, Pinard, M.A, McKenna, R. | Deposit date: | 2015-02-03 | Release date: | 2015-07-29 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.596 Å) | Cite: | Structural and biophysical characterization of the alpha-carbonic anhydrase from the gammaproteobacterium Thiomicrospira crunogena XCL-2: insights into engineering thermostable enzymes for CO2 sequestration. Acta Crystallogr.,Sect.D, 71, 2015
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7RL1
| AAVrh.10-7x capsid | Descriptor: | 2'-DEOXYADENOSINE-5'-MONOPHOSPHATE, 2'-DEOXYCYTIDINE-5'-MONOPHOSPHATE, Capsid protein VP1 | Authors: | Mietzsch, M, McKenna, R. | Deposit date: | 2021-07-23 | Release date: | 2021-09-08 | Last modified: | 2021-11-24 | Method: | ELECTRON MICROSCOPY (2.71 Å) | Cite: | Structural Study of Aavrh.10 Receptor and Antibody Interactions. J.Virol., 95, 2021
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7S1W
| The AAVrh.10-glycan complex | Descriptor: | Capsid protein VP1, beta-D-galactopyranose | Authors: | Mietzsch, M, McKenna, R. | Deposit date: | 2021-09-02 | Release date: | 2021-09-22 | Last modified: | 2021-12-01 | Method: | ELECTRON MICROSCOPY (3.09 Å) | Cite: | Structural Study of Aavrh.10 Receptor and Antibody Interactions. J.Virol., 95, 2021
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2QA0
| Structure of Adeno-Associated virus serotype 8 | Descriptor: | Capsid protein, SODIUM ION | Authors: | Nam, H.-J. | Deposit date: | 2007-06-14 | Release date: | 2008-04-08 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of adeno-associated virus serotype 8, a gene therapy vector. J.Virol., 81, 2007
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3IXO
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5DVX
| Crystal structure of the catalytic-domain of human carbonic anhydrase IX at 1.6 angstrom resolution | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, Carbonic anhydrase 9, ... | Authors: | Mahon, B.P, Socorro, L, Driscoll, J.M, McKenna, R. | Deposit date: | 2015-09-21 | Release date: | 2016-08-03 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (1.598 Å) | Cite: | The Structure of Carbonic Anhydrase IX Is Adapted for Low-pH Catalysis. Biochemistry, 55, 2016
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2ILI
| Refine atomic structure of human carbonic anhydrase II | Descriptor: | Carbonic anhydrase 2, ZINC ION | Authors: | Fisher, S.Z. | Deposit date: | 2006-10-02 | Release date: | 2007-06-05 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Atomic crystal and molecular dynamics simulation structures of human carbonic anhydrase II: insights into the proton transfer mechanism Biochemistry, 46, 2007
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3EKI
| Structural insights of the Mycoplasma hyorhinis protein Mh-p37: A putative thiamine pyrophosphate transporter | Descriptor: | BROMIDE ION, CALCIUM ION, GLYCEROL, ... | Authors: | Sippel, K.H, Robbins, A.H, Reutzel, R, McKenna, R. | Deposit date: | 2008-09-19 | Release date: | 2009-06-23 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural insights into the extracytoplasmic thiamine-binding lipoprotein p37 of Mycoplasma hyorhinis J.Bacteriol., 191, 2009
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3GZ0
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1KVP
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7NA6
| Cryo-EM structure of AAV True Type | Descriptor: | Capsid protein VP1 | Authors: | Bennett, A.D, McKenna, R. | Deposit date: | 2021-06-19 | Release date: | 2021-09-29 | Last modified: | 2021-10-13 | Method: | ELECTRON MICROSCOPY (3.35 Å) | Cite: | Comparative structural, biophysical, and receptor binding study of true type and wild type AAV2. J.Struct.Biol., 213, 2021
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1G0F
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1G0E
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2FLE
| Structural analysis of asymmetric inhibitor bound to the HIV-1 Protease V82A mutant | Descriptor: | (2S,2'S)-N,N'-[(2S,3S,4S,5S)-1-CYCLOHEXYL-3,4-DIHYDROXY-6-PHENYLHEXANE-2,5-DIYL]BIS[3-METHYL-2-({[METHYL(PYRIDIN-2-YLMETHYL)AMINO]CARBONYL}AMINO)BUTANAMIDE], GLYCEROL, pol protein | Authors: | Clemente, J.C, Robbins, A, Dunn, B.M, Sussman, F. | Deposit date: | 2006-01-05 | Release date: | 2007-01-16 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Design, synthesis, evaluation, and crystallographic-based structural studies of HIV-1 protease inhibitors with reduced response to the V82A mutation. J.Med.Chem., 51, 2008
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1SGU
| Comparing the Accumulation of Active Site and Non-active Site Mutations in the HIV-1 Protease | Descriptor: | N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE, POL polyprotein | Authors: | Clemente, J.C, Moose, R.E, Hemrajani, R, Govindasamy, L, Reutzel, R, Mckenna, R, Abandje-McKenna, M, Goodenow, M.M, Dunn, B.M. | Deposit date: | 2004-02-24 | Release date: | 2004-10-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Comparing the Accumulation of Active- and Nonactive-Site Mutations in the HIV-1 Protease. Biochemistry, 43, 2004
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