Loading
PDBj
English日本語简体中文繁體中文한국어
✖
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
Search by PDB author
6N1V
DownloadVisualize
BU of 6n1v by Molmil
Cryo-EM structure at 4.0 A resolution of vaccine-elicited antibody A12V163-a.01 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A12V163-a.01 Heavy chain, ...
Authors:Acharya, P, Kwong, P.D.
Deposit date:2018-11-12
Release date:2019-07-24
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
6MPG
DownloadVisualize
BU of 6mpg by Molmil
Cryo-EM structure at 3.2 A resolution of HIV-1 fusion peptide-directed antibody, A12V163-b.01, elicited by vaccination of Rhesus macaques, in complex with stabilized HIV-1 Env BG505 DS-SOSIP, which was also bound to antibodies VRC03 and PGT122
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, A12V163-b.01 Heavy Chain, ...
Authors:Acharya, P, Kwong, P.D.
Deposit date:2018-10-06
Release date:2019-07-24
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Antibody Lineages with Vaccine-Induced Antigen-Binding Hotspots Develop Broad HIV Neutralization.
Cell, 178, 2019
4JPW
DownloadVisualize
BU of 4jpw by Molmil
Crystal structure of broadly and potently neutralizing antibody 12a21 in complex with hiv-1 strain 93th057 gp120 mutant
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HEAVY CHAIN OF ANTIBODY 12A21, ...
Authors:Acharya, P, Luongo, T, Zhou, T, Kwong, P.D.
Deposit date:2013-03-19
Release date:2013-04-17
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.904 Å)
Cite:Somatic mutations of the immunoglobulin framework are generally required for broad and potent HIV-1 neutralization.
Cell(Cambridge,Mass.), 153, 2013
6CUF
DownloadVisualize
BU of 6cuf by Molmil
Cryo-EM structure at 4.2 A resolution of vaccine-elicited antibody vFP1.01 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
Authors:Acharya, P, Carragher, B, Potter, C.S, Kwong, P.D.
Deposit date:2018-03-26
Release date:2018-07-25
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4.2 Å)
Cite:Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV.
PLoS Pathog., 14, 2018
6CUE
DownloadVisualize
BU of 6cue by Molmil
Cryo-EM structure at 4.0 A resolution of vaccine-elicited antibody vFP7.04 in complex with HIV-1 Env BG505 DS-SOSIP, and antibodies VRC03 and PGT122
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Envelope glycoprotein gp120, ...
Authors:Acharya, P, Carragher, B, Potter, C.S, Kwong, P.D.
Deposit date:2018-03-26
Release date:2018-07-11
Last modified:2020-07-29
Method:ELECTRON MICROSCOPY (4 Å)
Cite:Complete functional mapping of infection- and vaccine-elicited antibodies against the fusion peptide of HIV.
PLoS Pathog., 14, 2018
6E5P
DownloadVisualize
BU of 6e5p by Molmil
Backbone model based on cryo-EM map at 8.5 A of domain-swapped, glycan-reactive, neutralizing antibody 2G12 bound to HIV-1 Env BG505 DS-SOSIP, which was also bound to CD4-binding site antibody VRC03
Descriptor: 2G12 Light chain, 2G12 heavy chain, Envelope glycoprotein gp120, ...
Authors:Acharya, P, Kwong, P.D.
Deposit date:2018-07-21
Release date:2019-02-13
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (8.8 Å)
Cite:Structural Survey of Broadly Neutralizing Antibodies Targeting the HIV-1 Env Trimer Delineates Epitope Categories and Characteristics of Recognition.
Structure, 27, 2019
8CSA
DownloadVisualize
BU of 8csa by Molmil
Triple mutant (K417N-E484K-N501Y) SARS-CoV-2 spike protein in the 3-RBD-Down conformation (S-GSAS-D614G-K417N-E484K-N501Y)
Descriptor: Spike glycoprotein
Authors:Gobeil, S, Acharya, P.
Deposit date:2022-05-12
Release date:2022-07-20
Last modified:2024-01-31
Method:ELECTRON MICROSCOPY (3.84 Å)
Cite:Effect of natural mutations of SARS-CoV-2 on spike structure, conformation, and antigenicity
Science, 2021
8U1D
DownloadVisualize
BU of 8u1d by Molmil
Cryo-EM structure of vaccine-elicited CD4 binding site antibody DH1285 bound to HIV-1 CH505TFchim.6R.SOSIP.664v4.1 Env Local Refinement
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DH1285 Heavy Chain, DH1285 Light Chain, ...
Authors:Thakur, B, Stalls, V.D, Acharya, P.
Deposit date:2023-08-31
Release date:2024-01-03
Method:ELECTRON MICROSCOPY (4.25 Å)
Cite:Rhesus macaque vaccine elicited antibody DH1285 Fab bound to the one of the gp120 promoter of CH505M5chimer.6R.SOSIP.664v4.1 Env
To be published
8FEJ
DownloadVisualize
BU of 8fej by Molmil
Langya Virus Fusion Protein (LayV-F) in Pre-Fusion Conformation
Descriptor: Fusion Protein
Authors:May, A.J, Pothula, K.R, Janowska, K, Acharya, P.
Deposit date:2022-12-06
Release date:2023-04-19
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (4.64 Å)
Cite:Structures of Langya Virus Fusion Protein Ectodomain in Pre- and Postfusion Conformation.
J.Virol., 97, 2023
8FEL
DownloadVisualize
BU of 8fel by Molmil
Langya Virus Fusion Protein (LayV-F) in Post-Fusion Conformation
Descriptor: Fusion Protein
Authors:May, A.J, Pothula, K.R, Janowska, K, Acharya, P.
Deposit date:2022-12-06
Release date:2023-04-19
Last modified:2024-04-24
Method:ELECTRON MICROSCOPY (4.64 Å)
Cite:Structures of Langya Virus Fusion Protein Ectodomain in Pre- and Postfusion Conformation.
J.Virol., 97, 2023
8GDO
DownloadVisualize
BU of 8gdo by Molmil
Crystal structure of DH1010 Fab
Descriptor: DH1010 Fab Heavy Chain, DH1010 Fab Light chain
Authors:Lindenberger, J, Acharya, P.
Deposit date:2023-03-06
Release date:2024-03-13
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of DH1010 Fab
To Be Published
6XRJ
DownloadVisualize
BU of 6xrj by Molmil
Crystal structure of the disulfide linked DH717.1 Fab dimer, derived from a macaque HIV-1 vaccine-induced Env glycan-reactive neutralizing antibody B cell lineage
Descriptor: DH717.1 heavy chain Fab fragment, DH717.1 light chain Fab fragment
Authors:Manne, K, Nicely, N.I, Acharya, P.
Deposit date:2020-07-13
Release date:2020-12-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.15 Å)
Cite:Fab-dimerized glycan-reactive antibodies are a structural category of natural antibodies.
Cell, 184, 2021
8DY6
DownloadVisualize
BU of 8dy6 by Molmil
Vaccine elicited Antibody MU89+S27Y bound to CH848.D949.10.17_N133D_N138T.DS.SOSIP.664 HIV-1 Env trimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Stalls, V, Acharya, P.
Deposit date:2022-08-03
Release date:2023-04-19
Method:ELECTRON MICROSCOPY (4.32 Å)
Cite:Mutation-Guided Vaccine Design: A Strategy for Developing Boosting Immunogens for HIV Broadly Neutralizing Antibody Induction
bioRxiv, 2022
8DKF
DownloadVisualize
BU of 8dkf by Molmil
Antibody DH1030.1 Fab fragment
Descriptor: DH1030.1 Heavy chain, DH1030.1 Light chain
Authors:Gobeil, S, Acharya, P.
Deposit date:2022-07-05
Release date:2023-07-12
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.79 Å)
Cite:DH1030.1 glycan reactive Ab
To Be Published
8DP1
DownloadVisualize
BU of 8dp1 by Molmil
Cryo-EM structure of HIV-1 Env(BG505.T332N SOSIP) in complex with DH1030.1 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1030.1 Fab Heavy chain, ...
Authors:Gobeil, S, Acharya, P.
Deposit date:2022-07-14
Release date:2023-07-19
Method:ELECTRON MICROSCOPY (3.46 Å)
Cite:Shared recognition mechanism for HIV-1 envelope-reactive V3 glycan broadly neutralizing B cell lineage maturation in humans and macaques
To Be Published
8DOW
DownloadVisualize
BU of 8dow by Molmil
Cryo-EM structure of HIV-1 Env(CH848 10.17 DS.SOSIP_DT) in complex with DH1030.1 Fab
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1030.1 Fab Heavy chain, ...
Authors:Gobeil, S, Acharya, P.
Deposit date:2022-07-14
Release date:2023-07-19
Method:ELECTRON MICROSCOPY (3.69 Å)
Cite:Shared recognition mechanism for HIV-1 envelope-reactive V3 glycan broadly neutralizing B cell lineage maturation in humans and macaques
To Be Published
8DTK
DownloadVisualize
BU of 8dtk by Molmil
Structure of RBD directed antibody DH1047 in complex with SARS-CoV-2 spike: Local refinement of RBD-Fab interace
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DH1047 Fab Heavy Chain, DH1047 Fab Light Chain, ...
Authors:May, A.J, Manne, K, Acharya, P.
Deposit date:2022-07-25
Release date:2023-08-02
Last modified:2024-02-28
Method:ELECTRON MICROSCOPY (3.77 Å)
Cite:Broadly neutralizing antibody induction by non-stabilized SARS-CoV-2 Spike mRNA vaccination in nonhuman primates.
Biorxiv, 2023
8DTO
DownloadVisualize
BU of 8dto by Molmil
Vaccine elicited Antibody MU89 bound to CH848.D949.10.17_N133D_N138T.DS.SOSIP.664 HIV-1 Env trimer
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Stalls, V, Acharya, P.
Deposit date:2022-07-26
Release date:2023-04-19
Last modified:2023-10-11
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:Mutation-Guided Vaccine Design: A Strategy for Developing Boosting Immunogens for HIV Broadly Neutralizing Antibody Induction
bioRxiv, 2022
8DPZ
DownloadVisualize
BU of 8dpz by Molmil
Local refinement of SARS-CoV-2 vaccine induced antibody DH1338 bound to SARS-CoV-2 HexaPro RBD Spike ectodomain
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, DH1338 Fab Heavy Chain, DH1338 Fab Light Chain, ...
Authors:Stalls, V, May, A.J, Acharya, P.
Deposit date:2022-07-18
Release date:2023-08-02
Method:ELECTRON MICROSCOPY (3.38 Å)
Cite:Local refinement of SARS-CoV-2 vaccine induced antibody Ab026500 bound to SARS-CoV-2 HexaPro RBD Spike ectodomain
To Be Published
7SG4
DownloadVisualize
BU of 7sg4 by Molmil
Structure of SARS-CoV S protein in complex with Receptor Binding Domain antibody DH1047
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, DH1047 Heavy chain, DH1047 light chain, ...
Authors:Gobeil, S, Acharya, P.
Deposit date:2021-10-04
Release date:2021-11-10
Last modified:2022-02-09
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:A broadly cross-reactive antibody neutralizes and protects against sarbecovirus challenge in mice.
Sci Transl Med, 14, 2022
8EU8
DownloadVisualize
BU of 8eu8 by Molmil
Cryo-EM structure of CH848 10.17DT DS-SOSIP-2P Env
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CH848 10.17DT SOSIP Envelope glycoprotein gp160
Authors:Wrapp, D, Acharya, P, Haynes, B.F.
Deposit date:2022-10-18
Release date:2023-01-04
Last modified:2023-02-08
Method:ELECTRON MICROSCOPY (3.73 Å)
Cite:Structure-Based Stabilization of SOSIP Env Enhances Recombinant Ectodomain Durability and Yield.
J.Virol., 97, 2023
6X2A
DownloadVisualize
BU of 6x2a by Molmil
SARS-CoV-2 u1S2q 1-RBD Up Spike Protein Trimer
Descriptor: Spike glycoprotein
Authors:Henderson, R, Acharya, P.
Deposit date:2020-05-20
Release date:2020-05-27
Last modified:2021-08-04
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Controlling the SARS-CoV-2 spike glycoprotein conformation.
Nat.Struct.Mol.Biol., 27, 2020
6X29
DownloadVisualize
BU of 6x29 by Molmil
SARS-CoV-2 rS2d Down State Spike Protein Trimer
Descriptor: Spike glycoprotein
Authors:Henderson, R, Acharya, P.
Deposit date:2020-05-20
Release date:2020-05-27
Last modified:2020-10-21
Method:ELECTRON MICROSCOPY (2.7 Å)
Cite:Controlling the SARS-CoV-2 spike glycoprotein conformation.
Nat.Struct.Mol.Biol., 27, 2020
6X2B
DownloadVisualize
BU of 6x2b by Molmil
SARS-CoV-2 u1S2q 2-RBD Up Spike Protein Trimer
Descriptor: Spike glycoprotein
Authors:Henderson, R, Acharya, P.
Deposit date:2020-05-20
Release date:2020-05-27
Last modified:2021-08-04
Method:ELECTRON MICROSCOPY (3.6 Å)
Cite:Controlling the SARS-CoV-2 spike glycoprotein conformation.
Nat.Struct.Mol.Biol., 27, 2020
6X2C
DownloadVisualize
BU of 6x2c by Molmil
SARS-CoV-2 u1S2q All Down RBD State Spike Protein Trimer
Descriptor: Spike glycoprotein
Authors:Henderson, R, Acharya, P.
Deposit date:2020-05-20
Release date:2020-05-27
Last modified:2021-07-07
Method:ELECTRON MICROSCOPY (3.2 Å)
Cite:Controlling the SARS-CoV-2 spike glycoprotein conformation.
Nat.Struct.Mol.Biol., 27, 2020

218853

PDB entries from 2024-04-24

PDB statisticsPDBj update infoContact PDBjnumon