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Crystal structure of a putative fructose-1,6-biphosphate aldolase from Coccidioides immitis solved by combined SAD MR
Descriptor:	IODIDE ION, Putative fructose-bisphosphate aldolase, ZINC ION
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2010-11-16
Release date:	2010-12-15
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	SAD phasing using iodide ions in a high-throughput structural genomics environment. J Struct Funct Genomics, 12, 2011

3LQW

Crystal structure of deoxyuridine 5-triphosphate nucleotidohydrolase from Entamoeba histolytica
Descriptor:	1,2-ETHANEDIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, GLYCEROL
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2010-02-10
Release date:	2010-03-09
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (1.3 Å)
Cite:	Crystal structure of deoxyuridine 5-triphosphate nucleotidohydrolase from Entamoeba histolytica To be Published

3LNC

Crystal structure of guanylate kinase from Anaplasma phagocytophilum
Descriptor:	GUANOSINE-5'-MONOPHOSPHATE, Guanylate kinase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2010-02-02
Release date:	2010-02-16
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (1.95 Å)
Cite:	Crystal structure of guanylate kinase from Anaplasma phagocytophilum TO BE PUBLISHED

3LO0

Crystal structure of inorganic pyrophosphatase from Ehrlichia chaffeensis
Descriptor:	Inorganic pyrophosphatase, SULFATE ION
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2010-02-03
Release date:	2010-02-16
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (1.95 Å)
Cite:	Crystal structure of inorganic pyrophosphatase from Ehrlichia chaffeensis TO BE PUBLISHED

3MBQ

Crystal structure of deoxyuridine 5-triphosphate nucleotidohydrolase from Brucella melitensis, orthorhombic crystal form
Descriptor:	1,2-ETHANEDIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase, GLYCEROL, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2010-03-25
Release date:	2010-04-21
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (2.1 Å)
Cite:	Crystal structure of deoxyuridine 5-triphosphate nucleotidohydrolase from Brucella melitensis, orthorhombic crystal form To be Published

3MDX

Crystal structure of deoxyuridine 5-triphosphate nucleotidohydrolase from Brucella melitensis, rhombohedral crystal form
Descriptor:	1,2-ETHANEDIOL, Deoxyuridine 5'-triphosphate nucleotidohydrolase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2010-03-31
Release date:	2010-04-21
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (1.45 Å)
Cite:	Crystal structure of deoxyuridine 5-triphosphate nucleotidohydrolase from Brucella melitensis, rhombohedral crystal form To be Published

3MEN

Crystal structure of acetylpolyamine aminohydrolase from Burkholderia pseudomallei, iodide soak
Descriptor:	Acetylpolyamine aminohydrolase, IODIDE ION, POTASSIUM ION, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2010-03-31
Release date:	2010-04-21
Last modified:	2024-02-21
Method:	X-RAY DIFFRACTION (2.2 Å)
Cite:	SAD phasing using iodide ions in a high-throughput structural genomics environment. J Struct Funct Genomics, 12, 2011

3MEB

Structure of cytoplasmic aspartate aminotransferase from giardia lamblia
Descriptor:	1,2-ETHANEDIOL, Aspartate aminotransferase, PYRIDOXAL-5'-PHOSPHATE, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2010-03-31
Release date:	2010-04-21
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (1.9 Å)
Cite:	Structures of aspartate aminotransferases from Trypanosoma brucei, Leishmania major and Giardia lamblia. Acta Crystallogr F Struct Biol Commun, 71, 2015

3NGJ

Crystal structure of a putative deoxyribose-phosphate aldolase from Entamoeba histolytica
Descriptor:	1,2-ETHANEDIOL, Deoxyribose-phosphate aldolase, SODIUM ION, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2010-06-11
Release date:	2010-07-21
Last modified:	2011-07-13
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Crystal structure of a putative deoxyribose-phosphate aldolase from Entamoeba histolytica To be Published

3O2E

Crystal structure of a bol-like protein from babesia bovis
Descriptor:	BolA-like protein, IODIDE ION, MAGNESIUM ION
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2010-07-22
Release date:	2010-10-13
Last modified:	2024-04-03
Method:	X-RAY DIFFRACTION (1.95 Å)
Cite:	SAD phasing using iodide ions in a high-throughput structural genomics environment. J.Struct.Funct.Genom., 12, 2011

5W07

CRYSTAL STRUCTURE OF THE INHA FROM MYCOBACTERIUM TUBERCULOSIS IN COMPLEX WITH AN12855, EBSI 4333.
Descriptor:	(~{N}~{E})-~{N}-[[2-[[2-ethylsulfonyl-1,1-bis(oxidanyl)-3,4-dihydro-2,3,1$l^{4}-benzodiazaborinin-7-yl]oxy]-5-(trifluoromethyl)phenyl]methylidene]hydroxylamine, Enoyl-[acyl-carrier-protein] reductase [NADH]
Authors:	Abendroth, J, Edwards, T.E, Lorimer, D.
Deposit date:	2017-05-30
Release date:	2018-06-13
Last modified:	2024-03-13
Method:	X-RAY DIFFRACTION (2.65 Å)
Cite:	Discovery of a cofactor-independent inhibitor of Mycobacterium tuberculosis InhA To Be Published

3RJM

CASPASE2 IN COMPLEX WITH CHDI LIGAND 33c
Descriptor:	Caspase-2, Peptide inhibitor (ACE)VDV(3PX)D-CHO
Authors:	Abendroth, J, Lorimer, D, Stewart, L, Maillard, M, Kiselyov, A.S.
Deposit date:	2011-04-15
Release date:	2011-09-21
Last modified:	2023-12-06
Method:	X-RAY DIFFRACTION (2.55 Å)
Cite:	Exploiting differences in caspase-2 and -3 S(2) subsites for selectivity: Structure-based design, solid-phase synthesis and in vitro activity of novel substrate-based caspase-2 inhibitors. Bioorg.Med.Chem., 19, 2011

8V7O

Fab fragment of human mAb #58 in complex with computationally optimized broadly reactive H1 influenza hemagglutinin X6
Descriptor:	#58 heavy chain, #58 light chain, Hemagglutinin
Authors:	Nagashima, K.A, Mousa, J.J.
Deposit date:	2023-12-04
Release date:	2024-04-10
Method:	ELECTRON MICROSCOPY (3.57 Å)
Cite:	Structural basis for the broad antigenicity of the computationally optimized influenza hemagglutinin X6 To Be Published

4WEC

Crystal structure of a Short chain dehydrogenase from Mycobacterium smegmatis
Descriptor:	1,2-ETHANEDIOL, MAGNESIUM ION, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2014-09-09
Release date:	2014-10-08
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (1.55 Å)
Cite:	Crystal structure of a Short chain dehydrogenase from Mycobacterium smegmatis to be published

4WJM

Crystal structure of Fructokinase from Brucella abortus 2308 with bound AMPPNP
Descriptor:	1,2-ETHANEDIOL, MAGNESIUM ION, MALONIC ACID, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2014-10-01
Release date:	2014-10-22
Last modified:	2023-12-27
Method:	X-RAY DIFFRACTION (1.7 Å)
Cite:	Crystal structure of Fructokinase from Brucella abortus 2308 with bound AMPPNP To Be Published

4WNY

Crystal structure of a protein from the universal stress protein family from Burkholderia pseudomallei
Descriptor:	Universal stress protein
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2014-10-14
Release date:	2014-11-05
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (2.25 Å)
Cite:	Crystal structure of a protein from the universal stress protein family from Burkholderia pseudomallei to be published

4WSO

X-ray crystal structure of a nicotinate nucleotide adenylyltransferase from Burkholderia thailandensis bound to NAD
Descriptor:	NICOTINAMIDE-ADENINE-DINUCLEOTIDE, PHOSPHATE ION, Probable nicotinate-nucleotide adenylyltransferase
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2014-10-28
Release date:	2014-11-12
Last modified:	2023-09-27
Method:	X-RAY DIFFRACTION (2.05 Å)
Cite:	X-ray crystal structure of a nicotinate nucleotide adenylyltransferase from Burkholderia thailandensis bound to NAD to be published

6XRS

Crystal structure of a GTP-binding protein EngA (Der homolog) from Neisseria gonorrhoeae bound to GDP
Descriptor:	CHLORIDE ION, GTPase Der, GUANOSINE-5'-DIPHOSPHATE, ...
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2020-07-13
Release date:	2020-09-23
Last modified:	2023-10-18
Method:	X-RAY DIFFRACTION (2.8 Å)
Cite:	Crystal structure of a GTP-binding protein EngA (Der homolog) from Neisseria gonorrhoeae bound to GDP To Be Published

6PTH

Crystal structure of a DnaN sliding clamp (DNA polymerase III subunit beta) from Pseudomonas aeruginosa bound to griselimycin
Descriptor:	Beta sliding clamp, Griselimycin, SULFATE ION
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2019-07-15
Release date:	2019-08-07
Last modified:	2023-11-15
Method:	X-RAY DIFFRACTION (3.05 Å)
Cite:	Crystal structure of a DnaN sliding clamp (DNA polymerase III subunit beta) from Pseudomonas aeruginosa bound to griselimycin To Be Published

6U3L

Crystal structure of Hemerythrin HHE cation binding domain-containing protein: Rv2633c homolog from Mycobacterium kansasii
Descriptor:	1,2-ETHANEDIOL, Hemerythrin HHE cation binding domain protein
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2019-08-22
Release date:	2020-01-22
Last modified:	2024-03-13
Method:	X-RAY DIFFRACTION (1.75 Å)
Cite:	Crystal structure of a hemerythrin-like protein from Mycobacterium kansasii and homology model of the orthologous Rv2633c protein of M. tuberculosis. Biochem.J., 477, 2020

3F0G

Co-crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase with CMP
Descriptor:	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, CYTIDINE-5'-MONOPHOSPHATE, ZINC ION
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2008-10-24
Release date:	2008-11-04
Last modified:	2023-09-06
Method:	X-RAY DIFFRACTION (2.08 Å)
Cite:	Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. J Struct Funct Genomics, 12, 2011

3F0D

High resolution crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphatase synthase from Burkholderia pseudomallei
Descriptor:	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, ZINC ION
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2008-10-24
Release date:	2008-11-04
Last modified:	2023-12-27
Method:	X-RAY DIFFRACTION (1.2 Å)
Cite:	Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. J Struct Funct Genomics, 12, 2011

3F0E

Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase from Burkholderia pseudomallei
Descriptor:	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase, MAGNESIUM ION, ZINC ION
Authors:	Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2008-10-24
Release date:	2008-11-04
Last modified:	2023-12-27
Method:	X-RAY DIFFRACTION (2.05 Å)
Cite:	Leveraging structure determination with fragment screening for infectious disease drug targets: MECP synthase from Burkholderia pseudomallei. J Struct Funct Genomics, 12, 2011

2LKY

Solution structure of MSMEG_1053, the second DUF3349 annotated protein in the genome of Mycobacterium smegmatis, Seattle Structural Genomics Center for Infectious Disease target MysmA.17112.b
Descriptor:	Uncharacterized protein
Authors:	Buchko, G.W, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2011-10-22
Release date:	2011-11-16
Last modified:	2023-06-14
Method:	SOLUTION NMR
Cite:	Structural diversity in the Mycobacteria DUF3349 superfamily. Protein Sci., 29, 2020

2M0N

Solution structure of a DUF3349 annotated protein from Mycobacterium abscessus, MAB_3403c. Seattle Structural Genomics Center for Infectious Disease target MyabA.17112.a.A2
Descriptor:	Putative uncharacterized protein
Authors:	Buchko, G.W, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:	2012-10-30
Release date:	2012-11-21
Last modified:	2023-06-14
Method:	SOLUTION NMR
Cite:	Structural diversity in the Mycobacteria DUF3349 superfamily. Protein Sci., 29, 2020

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