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1OM2
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SOLUTION NMR STRUCTURE OF THE MITOCHONDRIAL PROTEIN IMPORT RECEPTOR TOM20 FROM RAT IN A COMPLEX WITH A PRESEQUENCE PEPTIDE DERIVED FROM RAT ALDEHYDE DEHYDROGENASE (ALDH)
分子名称: PROTEIN (MITOCHONDRIAL ALDEHYDE DEHYDROGENASE), PROTEIN (MITOCHONDRIAL IMPORT RECEPTOR SUBUNIT TOM20)
著者Abe, Y, Shodai, T, Muto, T, Mihara, K, Torii, H, Nishikawa, S, Endo, T, Kohda, D.
登録日1999-04-23
公開日2000-02-02
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Structural basis of presequence recognition by the mitochondrial protein import receptor Tom20.
Cell(Cambridge,Mass.), 100, 2000
3WW6
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Crystal Structure of hen egg white lysozyme mutant N46D/D52S
分子名称: CHLORIDE ION, Lysozyme C
著者Abe, Y, Kubota, M, Ito, Y, Imoto, T, Ueda, T.
登録日2014-06-17
公開日2015-06-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Effect on catalysis by replacement of catalytic residue from hen egg white lysozyme to Venerupis philippinarum lysozyme.
Protein Sci., 25, 2016
3WW5
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Crystal Structure of hen egg white lysozyme mutant N46E/D52S
分子名称: CHLORIDE ION, Lysozyme C
著者Abe, Y, Kubota, M, Ito, Y, Imoto, T, Ueda, T.
登録日2014-06-17
公開日2015-06-17
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Effect on catalysis by replacement of catalytic residue from hen egg white lysozyme to Venerupis philippinarum lysozyme.
Protein Sci., 25, 2016
2D35
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BU of 2d35 by Molmil
Solution structure of Cell Division Reactivation Factor, CedA
分子名称: Cell division activator cedA
著者Abe, Y, Watanabe, N, Matsuda, Y, Yoshida, Y, Katayama, T, Ueda, T.
登録日2005-09-26
公開日2006-12-12
最終更新日2022-03-09
実験手法SOLUTION NMR
主引用文献Structural Analysis and Molecular Interaction of Cell Division Reactivation Factor, CedA from Escherichia coli
To be Published
2E0G
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BU of 2e0g by Molmil
DnaA N-terminal domain
分子名称: Chromosomal replication initiator protein dnaA
著者Abe, Y, Katayama, T, Ueda, T, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2006-10-07
公開日2007-05-01
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure and Function of DnaA N-Terminal Domains: Specific Sites and Mechanisms in Inter-DnaA Interaction and in DnaB Helicase Loading on oriC
To be Published
5YCQ
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BU of 5ycq by Molmil
Unique Specificity-Enhancing Factor for the AAA+ Lon Protease
分子名称: Heat shock protein HspQ
著者Abe, Y, Shioi, S, Kita, S, Nakata, H, Maenaka, K, Kohda, D, Katayama, T, Ueda, T.
登録日2017-09-08
公開日2018-04-11
実験手法X-RAY DIFFRACTION (2.503 Å)
主引用文献X-ray crystal structure of Escherichia coli HspQ, a protein involved in the retardation of replication initiation
FEBS Lett., 591, 2017
2RUP
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BU of 2rup by Molmil
Solution structure of rat P2X4 receptor head domain
分子名称: P2X purinoceptor 4
著者Abe, Y, Igawa, T, Tsuda, M, Inoue, K, Ueda, T.
登録日2014-11-12
公開日2015-02-04
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Solution structure of the rat P2X4 receptor head domain involved in inhibitory metal binding
FEBS Lett., 589, 2015
2RU8
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DnaT C-terminal domain
分子名称: Primosomal protein 1
著者Abe, Y, Tani, J, Fujiyama, S, Urabe, M, Sato, K, Aramaki, T, Katayama, T, Ueda, T.
登録日2014-01-29
公開日2014-10-08
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Structure and mechanism of the primosome protein DnaT-functional structures for homotrimerization, dissociation of ssDNA from the PriB·ssDNA complex, and formation of the DnaT·ssDNA complex.
Febs J., 281, 2014
1B9O
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BU of 1b9o by Molmil
HUMAN ALPHA-LACTALBUMIN, LOW TEMPERATURE FORM
分子名称: CALCIUM ION, PROTEIN (ALPHA-LACTALBUMIN)
著者Harata, K, Abe, Y, Muraki, M.
登録日1999-02-14
公開日1999-03-31
最終更新日2023-12-27
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Crystallographic evaluation of internal motion of human alpha-lactalbumin refined by full-matrix least-squares method.
J.Mol.Biol., 287, 1999
4K9G
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BU of 4k9g by Molmil
1.55 A Crystal Structure of Macrophage Migration Inhibitory Factor bound to ISO-66 and a related compound
分子名称: (4R,6Z)-6-(3-fluoro-4-hydroxyphenyl)-4-hydroxy-6-iminohexan-2-one, 1-[(5S)-3-(3-fluoro-4-hydroxyphenyl)-4,5-dihydro-1,2-oxazol-5-yl]propan-2-one, CHLORIDE ION, ...
著者Crichlow, G.V, Al-Abed, Y, Lolis, E.J.
登録日2013-04-19
公開日2014-09-24
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献ISO-66, a novel inhibitor of macrophage migration, shows efficacy in melanoma and colon cancer models.
INT J ONCOL., 45, 2014
1QQ2
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BU of 1qq2 by Molmil
CRYSTAL STRUCTURE OF A MAMMALIAN 2-CYS PEROXIREDOXIN, HBP23.
分子名称: CHLORIDE ION, THIOREDOXIN PEROXIDASE 2
著者Hirotsu, S, Abe, Y, Okada, K, Nagahara, N, Hori, H, Nishino, T, Hakoshima, T.
登録日1999-06-10
公開日1999-10-29
最終更新日2021-11-03
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Crystal structure of a multifunctional 2-Cys peroxiredoxin heme-binding protein 23 kDa/proliferation-associated gene product.
Proc.Natl.Acad.Sci.USA, 96, 1999
5WQV
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BU of 5wqv by Molmil
Crystal structure of PriB mutant - S55A
分子名称: Primosomal replication protein N
著者Fujiyama, S, Shiroishi, M, Katayama, T, Abe, Y, Ueda, T.
登録日2016-11-28
公開日2017-11-29
最終更新日2019-06-12
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Insight into the interaction between PriB and DnaT on bacterial DNA replication restart: Significance of the residues on PriB dimer interface and highly acidic region on DnaT.
Biochim Biophys Acta Proteins Proteom, 1867, 2019
2Z9S
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BU of 2z9s by Molmil
Crystal Structure Analysis of rat HBP23/Peroxiredoxin I, Cys52Ser mutant
分子名称: Peroxiredoxin-1
著者Matsumura, T, Okamoto, K, Nishino, T, Abe, Y.
登録日2007-09-25
公開日2007-11-20
最終更新日2021-11-10
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Dimer-Oligomer Interconversion of Wild-type and Mutant Rat 2-Cys Peroxiredoxin: DISULFIDE FORMATION AT DIMER-DIMER INTERFACES IS NOT ESSENTIAL FOR DECAMERIZATION
J.Biol.Chem., 283, 2008
4YZF
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BU of 4yzf by Molmil
Crystal structure of the anion exchanger domain of human erythrocyte Band 3
分子名称: 2,2'-ethane-1,2-diylbis{5-[(sulfanylmethyl)amino]benzenesulfonic acid}, Band 3 anion transport protein, FAB fragment of Immunoglobulin (IgG) molecule
著者Alguel, Y, Arakawa, T, Yugiri, T.K, Iwanari, H, Hatae, H, Iwata, M, Abe, Y, Hino, T, Suno, C.I, Kuma, H, Kang, D, Murata, T, Hamakubo, T, Cameron, A.D, Kobayashi, T, Hamasaki, N, Iwata, S.
登録日2015-03-25
公開日2015-11-04
最終更新日2015-11-18
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Crystal structure of the anion exchanger domain of human erythrocyte band 3.
Science, 350, 2015
5A16
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Crystal structure of Fab4201 raised against Human Erythrocyte Anion Exchanger 1
分子名称: FAB4201 HEAVY CHAIN
著者Arakawa, T, Kobayashi-Yugiri, T, Alguel, Y, Weyand, S, Iwanari, H, Hatae, H, Iwata, M, Abe, Y, Hino, T, Ikeda-Suno, C, Kuma, H, Kang, D, Murata, T, Hamakubo, T, Cameron, A, Kobayashi, T, Hamasaki, N, Iwata, S.
登録日2015-04-28
公開日2015-06-10
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Crystal Structure of the Anion Exchanger Domain of Human Erythrocyte Band 3
Science, 350, 2015
1JSF
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FULL-MATRIX LEAST-SQUARES REFINEMENT OF HUMAN LYSOZYME
分子名称: LYSOZYME, NITRATE ION
著者Harata, K, Abe, Y, Muraki, M.
登録日1998-01-05
公開日1998-04-29
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.15 Å)
主引用文献Full-matrix least-squares refinement of lysozymes and analysis of anisotropic thermal motion.
Proteins, 30, 1998
1JSE
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FULL-MATRIX LEAST-SQUARES REFINEMENT OF TURKEY LYSOZYME
分子名称: LYSOZYME, N-PROPANOL
著者Harata, K, Abe, Y, Muraki, M.
登録日1998-01-05
公開日1998-04-29
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.12 Å)
主引用文献Full-matrix least-squares refinement of lysozymes and analysis of anisotropic thermal motion.
Proteins, 30, 1998
1LJT
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BU of 1ljt by Molmil
Crystal Structure of Macrophage Migration Inhibitory Factor complexed with (S,R)-3-(4-hydroxyphenyl)-4,5-dihydro-5-isoxazole-acetic acid methyl ester (ISO-1)
分子名称: 3-(4-HYDROXYPHENYL)-4,5-DIHYDRO-5-ISOXAZOLE-ACETIC ACID METHYL ESTER, Macrophage migration inhibitory factor
著者Lubetsky, J.B, Dios, A, Han, J, Aljabari, B, Ruzsicska, B, Mitchell, R, Lolis, E, Al-Abed, Y.
登録日2002-04-22
公開日2002-11-27
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The Tautomerase Active Site of Macrophage Migration Inhibitory factor is a Potential Target for Discovery of Novel Anti-inflammatory Agents
J.Biol.Chem., 277, 2002
2OOW
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MIF Bound to a Fluorinated OXIM Derivative
分子名称: 3-FLUORO-4-HYDROXYBENZALDEHYDE O-(CYCLOHEXYLCARBONYL)OXIME, GLYCEROL, ISOPROPYL ALCOHOL, ...
著者Crichlow, G.V, Al-Abed, Y, Lolis, E.
登録日2007-01-26
公開日2007-06-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Alternative chemical modifications reverse the binding orientation of a pharmacophore scaffold in the active site of macrophage migration inhibitory factor.
J.Biol.Chem., 282, 2007
2OOZ
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Macrophage Migration Inhibitory Factor (MIF) Complexed with OXIM6 (an OXIM Derivative Not Containing a Ring in its R-group)
分子名称: 4-HYDROXYBENZALDEHYDE O-(3,3-DIMETHYLBUTANOYL)OXIME, GLYCEROL, ISOPROPYL ALCOHOL, ...
著者Crichlow, G.V, Al-Abed, Y, Lolis, E.
登録日2007-01-26
公開日2007-06-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Alternative chemical modifications reverse the binding orientation of a pharmacophore scaffold in the active site of macrophage migration inhibitory factor.
J.Biol.Chem., 282, 2007
2OOH
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Crystal Structure of MIF bound to a Novel Inhibitor, OXIM-11
分子名称: 4-HYDROXYBENZALDEHYDE O-(CYCLOHEXYLCARBONYL)OXIME, GLYCEROL, Macrophage migration inhibitory factor, ...
著者Crichlow, G.V, Al-Abed, Y, Lolis, E.
登録日2007-01-25
公開日2007-06-05
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Alternative chemical modifications reverse the binding orientation of a pharmacophore scaffold in the active site of macrophage migration inhibitory factor.
J.Biol.Chem., 282, 2007
2RT6
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Backbone 1H, 13C, and 15N Chemical Shift Assignments for PriC N-terminal domain
分子名称: Primosomal replication protein N''
著者Aramaki, T, Abe, Y, Katayama, T, Ueda, T.
登録日2013-04-24
公開日2013-08-07
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Solution structure of the N-terminal domain of a replication restart primosome factor, PriC, in Escherichia coli.
Protein Sci., 22, 2013
1WOC
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Crystal structure of PriB
分子名称: Primosomal replication protein n
著者Shioi, S, Ose, T, Maenaka, K, Abe, Y, Kohda, D, Katayama, T, Ueda, T.
登録日2004-08-13
公開日2005-01-25
最終更新日2012-12-05
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a biologically functional form of PriB from Escherichia coli reveals a potential single-stranded DNA-binding site
Biochem.Biophys.Res.Commun., 326, 2005
5Y25
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EGFR kinase domain mutant (T790M/L858R) with covalent ligand NS-062
分子名称: (2R)-N-[4-[(3-chloranyl-4-fluoranyl-phenyl)amino]-7-(3-morpholin-4-ylpropoxy)quinazolin-6-yl]-1-(2-fluoranylethanoyl)pyrrolidine-2-carboxamide, Epidermal growth factor receptor
著者Shiroishi, M, Abe, Y, Caaveiro, J.M.M, Sakamoto, S, Morimoto, S, Fuchida, H, Shindo, N, Ojida, A.
登録日2017-07-24
公開日2018-07-25
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.102 Å)
主引用文献Selective and reversible modification of kinase cysteines with chlorofluoroacetamides.
Nat.Chem.Biol., 15, 2019
2DQA
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Crystal Structure of Tapes japonica Lysozyme
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Lysozyme, PLATINUM (II) ION, ...
著者Goto, T, Kakuta, Y, Abe, Y, Takeshita, K, Imoto, T, Ueda, T.
登録日2006-05-24
公開日2007-06-12
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal Structure of Tapes japonica Lysozyme with Substrate Analogue: STRUCTURAL BASIS OF THE CATALYTIC MECHANISM AND MANIFESTATION OF ITS CHITINASE ACTIVITY ACCOMPANIED BY QUATERNARY STRUCTURAL CHANGE
J.Biol.Chem., 282, 2007

 

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