4X9H
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4X9G
| Crystal structure of Dscam1 isoform 6.44, N-terminal four Ig domains | 分子名称: | Down Syndrome Cell Adhesion Molecule isoform 6.44, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Chen, Q, Yu, Y, Li, S.A, Cheng, L. | 登録日 | 2014-12-11 | 公開日 | 2015-12-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.403 Å) | 主引用文献 | Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition Sci Adv, 2, 2016
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4X9I
| Crystal structure of Dscam1 isoform 9.44, N-terminal four Ig domains | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Down Syndrome Cell Adhesion Molecule, isoform 9.44, ... | 著者 | Chen, Q, Yu, Y, Li, S.A, cheng, L. | 登録日 | 2014-12-11 | 公開日 | 2015-12-16 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.904 Å) | 主引用文献 | Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition Sci Adv, 2, 2016
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4XB8
| Crystal structure of Dscam1 isoform 9.44, N-terminal four Ig domains (with zinc) | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Down Syndrome Cell Adhesion Molecule, ... | 著者 | Chen, Q, Yu, Y, Li, S.A, cheng, L. | 登録日 | 2014-12-16 | 公開日 | 2015-12-16 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.202 Å) | 主引用文献 | Structural basis of Dscam1 homodimerization: Insights into context constraint for protein recognition Sci Adv, 2, 2016
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4D90
| Crystal Structure of Del-1 EGF domains | 分子名称: | 2-acetamido-2-deoxy-beta-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | 著者 | Chen, Q, Schurpf, T, Springer, T, Wang, J. | 登録日 | 2012-01-11 | 公開日 | 2012-05-30 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.601 Å) | 主引用文献 | The RGD finger of Del-1 is a unique structural feature critical for integrin binding. Faseb J., 26, 2012
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3Q5Y
| V beta/V beta homodimerization-based pre-TCR model suggested by TCR beta crystal structures | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, DI(HYDROXYETHYL)ETHER, GLYCEROL, ... | 著者 | Chen, Q, Zhang, H, Wang, J.-H. | 登録日 | 2010-12-30 | 公開日 | 2011-03-09 | 最終更新日 | 2014-10-15 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A conserved hydrophobic patch on Vbeta domains revealed by TCRbeta chain crystal structures: implications for pre-TCR dimerization Front Immunol, 2, 2011
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3Q5T
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4IRE
| Crystal structure of GLIC with mutations at the loop C region | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ACETATE ION, OXALATE ION, ... | 著者 | Chen, Q, Pan, J, Liang, Y.H, Xu, Y, Tang, P. | 登録日 | 2013-01-14 | 公開日 | 2013-04-24 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | 主引用文献 | Signal transduction pathways in the pentameric ligand-gated ion channels. Plos One, 8, 2013
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4QH9
| Crystal structure of Mn2+ bound human APE1 | 分子名称: | 1,2-ETHANEDIOL, DNA-(apurinic or apyrimidinic site) lyase, MANGANESE (II) ION | 著者 | Chen, Q, He, H, Georgiadis, M.M. | 登録日 | 2014-05-27 | 公開日 | 2014-11-12 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.175 Å) | 主引用文献 | High-resolution crystal structures reveal plasticity in the metal binding site of apurinic/apyrimidinic endonuclease I. Biochemistry, 53, 2014
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6KNZ
| Crystal structure of T2R-TTL-KXO1 complex | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-[5-[4-(2-morpholin-4-ylethoxy)phenyl]pyridin-2-yl]-~{N}-(phenylmethyl)ethanamide, CALCIUM ION, ... | 著者 | Chen, Q, Yu, Y. | 登録日 | 2019-08-07 | 公開日 | 2019-10-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.475 Å) | 主引用文献 | Reversible binding of the anticancer drug KXO1 (tirbanibulin) to the colchicine-binding site of beta-tubulin explains KXO1's low clinical toxicity. J.Biol.Chem., 294, 2019
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8J4U
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8H2F
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8H18
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8HI1
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6LP7
| Crystal structure of human DHODH in complex with inhibitor 0944 | 分子名称: | 3-[3,5-bis(fluoranyl)-4-(3-methoxyphenyl)phenyl]benzo[f]benzotriazole-4,9-dione, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ... | 著者 | Chen, Q, Yu, Y. | 登録日 | 2020-01-09 | 公開日 | 2020-09-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.802 Å) | 主引用文献 | Bifunctional Naphtho[2,3- d ][1,2,3]triazole-4,9-dione Compounds Exhibit Antitumor Effects In Vitro and In Vivo by Inhibiting Dihydroorotate Dehydrogenase and Inducing Reactive Oxygen Species Production. J.Med.Chem., 63, 2020
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6LP6
| Crystal structure of human DHODH in complex with inhibitor 1214 | 分子名称: | 3-[3,5-bis(fluoranyl)-4-[2-fluoranyl-5-(hydroxymethyl)phenyl]phenyl]benzo[f]benzotriazole-4,9-dione, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ... | 著者 | Chen, Q, Yu, Y. | 登録日 | 2020-01-09 | 公開日 | 2020-09-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.795 Å) | 主引用文献 | Bifunctional Naphtho[2,3- d ][1,2,3]triazole-4,9-dione Compounds Exhibit Antitumor Effects In Vitro and In Vivo by Inhibiting Dihydroorotate Dehydrogenase and Inducing Reactive Oxygen Species Production. J.Med.Chem., 63, 2020
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6LP8
| Crystal structure of human DHODH in complex with inhibitor 1243 | 分子名称: | 3-[4-[3-(dimethylamino)phenyl]-3,5-bis(fluoranyl)phenyl]benzo[f]benzotriazole-4,9-dione, ACETATE ION, Dihydroorotate dehydrogenase (quinone), ... | 著者 | Chen, Q, Yu, Y. | 登録日 | 2020-01-09 | 公開日 | 2020-09-30 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | Bifunctional Naphtho[2,3- d ][1,2,3]triazole-4,9-dione Compounds Exhibit Antitumor Effects In Vitro and In Vivo by Inhibiting Dihydroorotate Dehydrogenase and Inducing Reactive Oxygen Species Production. J.Med.Chem., 63, 2020
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7Y73
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7Y8I
| Crystal structure of sDscam FNIII3 domain, isoform alpha7 | 分子名称: | CHLORIDE ION, DI(HYDROXYETHYL)ETHER, Dscam, ... | 著者 | Chen, Q, Yu, Y, Cheng, J. | 登録日 | 2022-06-24 | 公開日 | 2023-05-24 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural basis for the self-recognition of sDSCAM in Chelicerata. Nat Commun, 14, 2023
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7Y9A
| Crystal structure of sDscam Ig1-2 domains, isoform beta2v6 | 分子名称: | Down Syndrome Cell Adhesion Molecules, beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[beta-L-fucopyranose-(1-3)][beta-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose | 著者 | Chen, Q, Yu, Y, Cheng, J. | 登録日 | 2022-06-24 | 公開日 | 2023-05-24 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Structural basis for the self-recognition of sDSCAM in Chelicerata. Nat Commun, 14, 2023
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7Y5J
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7Y8S
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7Y6O
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7Y54
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7Y5R
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