8J4U

Structure of HerA-Sir2 complex from Escherichia coli Nezha system

This is a non-PDB format compatible entry.

Summary for 8J4U

• Entry DOI: 10.2210/pdb8j4u/pdb
• EMDB information: 35978
• Descriptor: SIR2-like domain-containing protein, Nucleoside triphosphate hydrolase, [(2R,3S,4R,5R)-5-(6-AMINOPURIN-9-YL)-3,4-DIHYDROXY-OXOLAN-2-YL]METHYL [HYDROXY-[[(2R,3S,4R,5S)-3,4,5-TRIHYDROXYOXOLAN-2-YL]METHOXY]PHOSPHORYL] HYDROGEN PHOSPHATE, ... (5 entities in total)
• Functional Keywords: defense system hera sir2, immune system
• Biological source: Escherichia coli; More
• Total number of polymer chains: 18
• Total formula weight: 981756.25

Authors

Chen, Q.,Yu, Y. (deposition date: 2023-04-20, release date: 2024-01-03)

• Primary citation: Tang, D.,Chen, Y.,Chen, H.,Jia, T.,Chen, Q.,Yu, Y.; Multiple enzymatic activities of a Sir2-HerA system cooperate for anti-phage defense.; Mol.Cell, 83:4600-4613.e6, 2023; PubMed: 38096825; DOI: 10.1016/j.molcel.2023.11.010

Experimental method

ELECTRON MICROSCOPY (2.97 Å)