5ZOA
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7V3O
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7V36
| The complex structure of soBcmB and its intermediate product 2a | Descriptor: | (3Z,6S)-3-[(2R)-2-methyl-2,3-bis(oxidanyl)propylidene]-6-[(2S)-4-oxidanylbutan-2-yl]piperazine-2,5-dione, 2-OXOGLUTARIC ACID, CHLORIDE ION, ... | Authors: | Wu, L, Zhou, J.H. | Deposit date: | 2021-08-10 | Release date: | 2023-02-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.96009171 Å) | Cite: | The complex structure of SoBcmB and its intermediate product To Be Published
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7V3E
| The complex structure of soBcmB and its intermediate product 1a | Descriptor: | (3S,6Z)-3-[(2S)-butan-2-yl]-6-[(2R)-2-methyl-2,3-bis(oxidanyl)propylidene]piperazine-2,5-dione, 2-OXOGLUTARIC ACID, CHLORIDE ION, ... | Authors: | Wu, L, Zhou, J.H. | Deposit date: | 2021-08-10 | Release date: | 2023-02-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | The crystal structure of SoBcmB and its side way intermediate product To Be Published
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7V2U
| The complex structure of SoBcmB and its product 2f | Descriptor: | (1S,5S,6S)-5-methyl-1-[(1S,2S)-2-methyl-1,2,3-tris(oxidanyl)propyl]-2-oxa-7,9-diazabicyclo[4.2.2]decane-8,10-dione, 2-OXOGLUTARIC ACID, CHLORIDE ION, ... | Authors: | Wu, L, Zhou, J.H. | Deposit date: | 2021-08-09 | Release date: | 2023-02-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.00009918 Å) | Cite: | The complex structure of SoBcmB and its product 2f To Be Published
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7V3N
| The complex structure of soBcmB-D307A and its natural precursor 2 | Descriptor: | (3S,6S)-3-((R)-2,3-dihydroxy-2-methylpropyl)-6-((S)-4-hydroxybutan-2-yl)piperazine-2,5-dione, 2-OXOGLUTARIC ACID, FE (II) ION, ... | Authors: | Wu, L, Zhou, J.H. | Deposit date: | 2021-08-10 | Release date: | 2023-02-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.850011 Å) | Cite: | The complex structure of SoBcmB mutant D307A and its substrate To Be Published
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7V2X
| The complex structure of soBcmB and its substrate 1 | Descriptor: | (3S,6S)-3-[(2S)-butan-2-yl]-6-[(2R)-2-methyl-2,3-bis(oxidanyl)propyl]piperazine-2,5-dion, 2-OXOGLUTARIC ACID, FE (II) ION, ... | Authors: | Wu, L, Zhou, J.H. | Deposit date: | 2021-08-10 | Release date: | 2023-02-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.08387423 Å) | Cite: | The crystal structure of SoBcmB and its side way substrate To Be Published
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7V34
| The complex structure of soBcmB and its product 1d | Descriptor: | (3S,4S,5S,8S)-8-[(2S)-butan-2-yl]-3-methyl-3,4-bis(oxidanyl)-1-oxa-7,10-diazaspiro[4.5]decane-6,9-dione, 2-OXOGLUTARIC ACID, CHLORIDE ION, ... | Authors: | Wu, L, Zhou, J.H. | Deposit date: | 2021-08-10 | Release date: | 2023-02-15 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.000169 Å) | Cite: | The complex structure of SoBcmB and its side way product To Be Published
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7ETL
| The crystal structure of FtmOx1-Y68F | Descriptor: | 1,2-ETHANEDIOL, 2-OXOGLUTARIC ACID, CHLORIDE ION, ... | Authors: | Zhou, J.H, Wu, L. | Deposit date: | 2021-05-13 | Release date: | 2021-12-01 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.992128 Å) | Cite: | Structural Insight into the Catalytic Mechanism of the Endoperoxide Synthase FtmOx1. Angew.Chem.Int.Ed.Engl., 61, 2022
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7ETK
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7WZV
| The structure of a Twitch Radical SAM Dehydrogenase SpeY | Descriptor: | (1~{S},2~{R},4~{S},5~{R})-2,4-bis(methylamino)-6-[(2~{S},3~{R},4~{S},6~{R})-6-methyl-3,4-bis(oxidanyl)oxan-2-yl]oxy-cyclohexane-1,3,5-triol, 1,2-ETHANEDIOL, 4Fe-4S cluster-binding domain-containing protein, ... | Authors: | Zhou, J.H, Hou, X.L. | Deposit date: | 2022-02-19 | Release date: | 2022-12-28 | Method: | X-RAY DIFFRACTION (1.899313 Å) | Cite: | Dioxane Bridge Formation during the Biosynthesis of Spectinomycin Involves a Twitch Radical S -Adenosyl Methionine Dehydrogenase That May Have Evolved from an Epimerase. J.Am.Chem.Soc., 144, 2022
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4O08
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4NZZ
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4O98
| Crystal structure of Pseudomonas oleovorans PoOPH mutant H250I/I263W | Descriptor: | ZINC ION, organophosphorus hydrolase | Authors: | Luo, X.J, Kong, X.D, Zhao, J, Chen, Q, Zhou, J.H, Xu, J.H. | Deposit date: | 2014-01-02 | Release date: | 2014-12-03 | Last modified: | 2017-11-22 | Method: | X-RAY DIFFRACTION (2.251 Å) | Cite: | Switching a newly discovered lactonase into an efficient and thermostable phosphotriesterase by simple double mutations His250Ile/Ile263Trp Biotechnol.Bioeng., 111, 2014
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5HSJ
| Structure of tyrosine decarboxylase complex with PLP at 1.9 Angstroms resolution | Descriptor: | PYRIDOXAL-5'-PHOSPHATE, Putative decarboxylase | Authors: | Ni, Y, Zhou, J, Zhu, H, Zhang, K. | Deposit date: | 2016-01-25 | Release date: | 2016-09-14 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Crystal structure of tyrosine decarboxylase and identification of key residues involved in conformational swing and substrate binding Sci Rep, 6, 2016
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4EML
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5YB5
| The complex crystal structure of VrEH2 mutant M263N with SNO | Descriptor: | (S)-PARA-NITROSTYRENE OXIDE, Epoxide hydrolase | Authors: | Li, F.L, Chen, F.F, Chen, Q, Kong, X.D, Yu, H.L, Xu, J.H. | Deposit date: | 2017-09-03 | Release date: | 2018-09-05 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.903 Å) | Cite: | Regioselectivity Engineering of Epoxide Hydrolase: Near-Perfect Enantioconvergence through a Single Site Mutation Acs Catalysis, 8, 2018
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5YQT
| Crystal Structure of the L74F/M78V/I80V/L114F mutant of LEH complexed with cyclopentene oxide | Descriptor: | (1R,5S)-6-oxabicyclo[3.1.0]hexane, Limonene-1,2-epoxide hydrolase | Authors: | Kong, X.D, Sun, Z.T, Wu, L, Reetz, M.T, Zhou, J.H, Xu, J.H. | Deposit date: | 2017-11-07 | Release date: | 2018-06-27 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural and Computational Insight into the Catalytic Mechanism of Limonene Epoxide Hydrolase Mutants in Stereoselective Transformations. J. Am. Chem. Soc., 140, 2018
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7BQK
| The structure of PdxI in complex with its substrate analogue | Descriptor: | 1,2-ETHANEDIOL, 3-[(E,2S,4S)-2,4-dimethyloct-6-enoyl]-4-oxidanyl-1H-pyridin-2-one, GLYCEROL, ... | Authors: | Cai, Y.J, Ohashi, M, Zhou, J.H, Tang, Y. | Deposit date: | 2020-03-24 | Release date: | 2020-10-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.99 Å) | Cite: | An enzymatic Alder-ene reaction. Nature, 586, 2020
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7BQL
| The crystal structure of PdxI complex with the Alder-ene adduct | Descriptor: | 3-[(1R,2S,4R,6S)-2-ethenyl-4,6-dimethyl-cyclohexyl]-4-oxidanyl-1H-pyridin-2-one, DI(HYDROXYETHYL)ETHER, Methyltransf_2 domain-containing protein | Authors: | Cai, Y.J, Ohashi, M, Zhou, J.H, Tang, Y. | Deposit date: | 2020-03-24 | Release date: | 2020-10-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.396 Å) | Cite: | An enzymatic Alder-ene reaction. Nature, 586, 2020
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7BQJ
| The structure of PdxI | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Methyltransf_2 domain-containing protein, ... | Authors: | Cai, Y.J, Ohashi, M, Zhou, J.H, Tang, Y. | Deposit date: | 2020-03-24 | Release date: | 2020-10-14 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | An enzymatic Alder-ene reaction. Nature, 586, 2020
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7BQO
| The structure of HpiI in complex with its substrate analogue | Descriptor: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 3-[(E,2S,4S)-2,4-dimethyloct-6-enoyl]-4-oxidanyl-1H-pyridin-2-one, GLYCEROL, ... | Authors: | Cai, Y.J, Ohashi, M, Zhou, J.H, Tang, Y. | Deposit date: | 2020-03-25 | Release date: | 2020-10-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.53 Å) | Cite: | An enzymatic Alder-ene reaction. Nature, 586, 2020
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7BQP
| The structure of HpiI | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, GLYCEROL, ... | Authors: | Cai, Y.J, Ohashi, M, Zhou, J.H, Tang, Y. | Deposit date: | 2020-03-25 | Release date: | 2020-10-14 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.33 Å) | Cite: | An enzymatic Alder-ene reaction. Nature, 586, 2020
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6ISQ
| structure of Lipase mutant with oxided Cys-His-Asp catalytic triad | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, ISOPROPYL ALCOHOL, ... | Authors: | Cen, Y.X, Zhou, J.H, Wu, Q. | Deposit date: | 2018-11-18 | Release date: | 2019-07-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution. Nat Commun, 10, 2019
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6ISR
| structure of lipase mutant with Cys-His-Asp catalytic triad | Descriptor: | DI(HYDROXYETHYL)ETHER, Lipase B, NICKEL (II) ION, ... | Authors: | Cen, Y.X, Zhou, J.H, Wu, Q. | Deposit date: | 2018-11-18 | Release date: | 2019-07-24 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Artificial cysteine-lipases with high activity and altered catalytic mechanism created by laboratory evolution. Nat Commun, 10, 2019
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