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4CYE
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BU of 4cye by Molmil
Crystal structure of avian FAK FERM domain FAK31-405 at 3.2A
Descriptor: FOCAL ADHESION KINASE 1
Authors:Goni, G.M, Epifano, C, Boskovic, J, Camacho-Artacho, M, Zhou, J, Martin, M.T, Eck, M.J, Kremer, L, Graeter, F, Gervasio, F.L, Perez-Moreno, M, Lietha, D.
Deposit date:2014-04-10
Release date:2014-04-23
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Phosphatidylinositol 4,5-Bisphosphate Triggers Activation of Focal Adhesion Kinase by Inducing Clustering and Conformational Changes.
Proc.Natl.Acad.Sci.USA, 111, 2014
8WQ4
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BU of 8wq4 by Molmil
Structural basis of translation inhibition by a valine tRNA-derived fragment
Descriptor: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ...
Authors:Wang, Y.H, Zhou, J.
Deposit date:2023-10-11
Release date:2024-04-10
Method:ELECTRON MICROSCOPY (4.53 Å)
Cite:Structural basis of translation inhibition by a valine tRNA-derived fragment
To Be Published
8WKP
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BU of 8wkp by Molmil
Structural basis of translation inhibition by a valine tRNA-derived fragment
Descriptor: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ...
Authors:Wang, Y.H, Zhou, J.
Deposit date:2023-09-28
Release date:2024-04-10
Method:ELECTRON MICROSCOPY (4.62 Å)
Cite:Structural basis of translation inhibition by a valine tRNA-derived fragment
To Be Published
8WQ2
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BU of 8wq2 by Molmil
Structural basis of translation inhibition by a valine tRNA-derived fragment
Descriptor: 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ...
Authors:Wang, Y.H, Zhou, J.
Deposit date:2023-10-10
Release date:2024-04-10
Method:ELECTRON MICROSCOPY (4.1 Å)
Cite:Structural basis of translation inhibition by a valine tRNA-derived fragment
To Be Published
3MGT
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BU of 3mgt by Molmil
Crystal structure of a H5-specific CTL epitope variant derived from H5N1 influenza virus in complex with HLA-A*0201
Descriptor: 10-meric peptide from Hemagglutinin, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Sun, Y, Liu, J, Yang, M, Gao, F, Zhou, J, Kitamura, Y.
Deposit date:2010-04-07
Release date:2010-05-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.197 Å)
Cite:Identification and structural definition of H5-specific CTL epitopes restricted by HLA-A*0201 derived from the H5N1 subtype of influenza A viruses
J.Gen.Virol., 91, 2010
3MGO
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BU of 3mgo by Molmil
Crystal structure of a H5-specific CTL epitope derived from H5N1 influenza virus in complex with HLA-A*0201
Descriptor: 10-meric peptide from Hemagglutinin, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
Authors:Sun, Y, Liu, J, Yang, M, Gao, F, Zhou, J, Kitamura, Y.
Deposit date:2010-04-07
Release date:2010-05-19
Last modified:2023-11-01
Method:X-RAY DIFFRACTION (2.297 Å)
Cite:Identification and structural definition of H5-specific CTL epitopes restricted by HLA-A*0201 derived from the H5N1 subtype of influenza A viruses
J.Gen.Virol., 91, 2010
1CW3
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BU of 1cw3 by Molmil
HUMAN MITOCHONDRIAL ALDEHYDE DEHYDROGENASE COMPLEXED WITH NAD+ AND MN2+
Descriptor: MAGNESIUM ION, MANGANESE (II) ION, MITOCHONDRIAL ALDEHYDE DEHYDROGENASE, ...
Authors:Ni, L, Zhou, J, Hurley, T.D, Weiner, H.
Deposit date:1999-08-25
Release date:1999-08-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.58 Å)
Cite:Human liver mitochondrial aldehyde dehydrogenase: three-dimensional structure and the restoration of solubility and activity of chimeric forms.
Protein Sci., 8, 1999
4LJY
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BU of 4ljy by Molmil
Crystal structure of RNA splicing effector Prp5 in complex with ADP
Descriptor: (4R)-2-METHYLPENTANE-2,4-DIOL, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Zhang, Z.-M, Li, J, Yang, F, Xu, Y, Zhou, J.
Deposit date:2013-07-05
Release date:2013-12-11
Last modified:2019-12-25
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Crystal structure of Prp5p reveals interdomain interactions that impact spliceosome assembly.
Cell Rep, 5, 2013
4LK2
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BU of 4lk2 by Molmil
Crystal structure of RNA splicing effector Prp5
Descriptor: NICKEL (II) ION, Pre-mRNA-processing ATP-dependent RNA helicase PRP5
Authors:Zhang, Z.-M, Li, J, Yang, F, Xu, Y, Zhou, J.
Deposit date:2013-07-05
Release date:2013-12-11
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.12 Å)
Cite:Crystal structure of Prp5p reveals interdomain interactions that impact spliceosome assembly.
Cell Rep, 5, 2013
8HKO
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BU of 8hko by Molmil
Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to Rucaparib
Descriptor: GLYCEROL, Poly [ADP-ribose] polymerase 2, Rucaparib
Authors:Wang, X.Y, Zhou, J, Xu, B.L.
Deposit date:2022-11-27
Release date:2024-05-01
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to Rucaparib
To Be Published
8HKS
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BU of 8hks by Molmil
Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to Pamiparib(BGB-290)
Descriptor: (2R)-14-fluoro-2-methyl-6,9,10,19-tetrazapentacyclo[14.2.1.02,6.08,18.012,17]nonadeca-1(18),8,12(17),13,15-pentaen-11-one, GLYCEROL, Poly [ADP-ribose] polymerase 2
Authors:Wang, X.Y, Zhou, J, Xu, B.L.
Deposit date:2022-11-28
Release date:2024-05-01
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to Pamiparib
To Be Published
8HLJ
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BU of 8hlj by Molmil
Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to Olaparib (AZD2281)
Descriptor: 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-one, Poly [ADP-ribose] polymerase 2
Authors:Wang, X.Y, Zhou, J, Xu, B.L.
Deposit date:2022-11-30
Release date:2024-05-01
Method:X-RAY DIFFRACTION (2.24 Å)
Cite:Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to Olaparib (AZD2281)
To Be Published
1YGH
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BU of 1ygh by Molmil
HAT DOMAIN OF GCN5 FROM SACCHAROMYCES CEREVISIAE
Descriptor: GLYCEROL, PROTEIN (TRANSCRIPTIONAL ACTIVATOR GCN5)
Authors:Trievel, R.C, Rojas, J.R, Sterner, D.E, Venkataramani, R, Wang, L, Zhou, J, Allis, C.D, Berger, S.L, Marmorstein, R.
Deposit date:1999-05-27
Release date:1999-08-02
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Crystal structure and mechanism of histone acetylation of the yeast GCN5 transcriptional coactivator.
Proc.Natl.Acad.Sci.USA, 96, 1999
8HLR
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BU of 8hlr by Molmil
Human ADP-ribosyltransferase 1 (PARP1) catalytic domain bound to Fluzoparib (SHR3162)
Descriptor: Fluzoparib, Poly [ADP-ribose] polymerase 1, processed C-terminus, ...
Authors:Wang, X.Y, Zhou, J, Xu, B.L.
Deposit date:2022-11-30
Release date:2024-05-01
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:Human ADP-ribosyltransferase 1 (PARP1) catalytic domain bound to Fluzoparib (SHR3162)
To Be Published
8HKN
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BU of 8hkn by Molmil
Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to approved drug Fluzoparib
Descriptor: Fluzoparib, GLYCEROL, Poly [ADP-ribose] polymerase 2
Authors:Wang, X.Y, Zhou, J, Xu, B.L.
Deposit date:2022-11-27
Release date:2024-05-01
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to approved drug Fluzoparib
To Be Published
8HLQ
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BU of 8hlq by Molmil
Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to Niraparib (MK-4827)
Descriptor: 2-{4-[(3S)-piperidin-3-yl]phenyl}-2H-indazole-7-carboxamide, GLYCEROL, Poly [ADP-ribose] polymerase 2
Authors:Wang, X.Y, Zhou, J, Xu, B.L.
Deposit date:2022-11-30
Release date:2024-05-01
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Mutated human ADP-ribosyltransferase 2 (PARP2) catalytic domain bound to Niraparib (MK-4827)
To Be Published
1ZCT
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BU of 1zct by Molmil
structure of glycogenin truncated at residue 270 in a complex with UDP
Descriptor: Glycogenin-1, MANGANESE (II) ION, URIDINE-5'-DIPHOSPHATE
Authors:Hurley, T.D, Stout, S.L, Miner, E, Zhou, J, Roach, P.J.
Deposit date:2005-04-13
Release date:2005-04-26
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Requirements for catalysis in mammalian glycogenin.
J.Biol.Chem., 280, 2005
1ZDF
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BU of 1zdf by Molmil
Ser162 mutant of glycogenin complexed with UDP-glucose and manganese
Descriptor: Glycogenin-1, MANGANESE (II) ION, SULFATE ION, ...
Authors:Hurley, T.D, Stout, S.L, Miner, E, Zhou, J, Roach, P.J.
Deposit date:2005-04-14
Release date:2005-04-26
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.45 Å)
Cite:Requirements for catalysis in mammalian glycogenin.
J.Biol.Chem., 280, 2005
1ZCY
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BU of 1zcy by Molmil
apo form of a mutant of glycogenin in which Asp159 is replaced by Ser
Descriptor: Glycogenin-1, SULFATE ION
Authors:Hurley, T.D, Stout, S.L, Miner, E, Zhou, J, Roach, P.J.
Deposit date:2005-04-13
Release date:2005-04-26
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.99 Å)
Cite:Requirements for catalysis in mammalian glycogenin.
J.Biol.Chem., 280, 2005
1ZCU
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BU of 1zcu by Molmil
apo form of the 162S mutant of glycogenin
Descriptor: Glycogenin-1
Authors:Hurley, T.D, Stout, S.L, Miner, E, Zhou, J, Roach, P.J.
Deposit date:2005-04-13
Release date:2005-04-26
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2 Å)
Cite:Requirements for catalysis in mammalian glycogenin.
J.Biol.Chem., 280, 2005
1ZDG
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BU of 1zdg by Molmil
Ser159 mutant of glycogenin complexed with UDP-glucose and manganese
Descriptor: Glycogenin-1, MANGANESE (II) ION, SULFATE ION, ...
Authors:Hurley, T.D, Stout, S.L, Miner, E, Zhou, J, Roach, P.J.
Deposit date:2005-04-14
Release date:2005-04-26
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Requirements for catalysis in mammalian glycogenin.
J.Biol.Chem., 280, 2005
1ZCV
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BU of 1zcv by Molmil
apo form of a mutant of glycogenin in which Asp159 is replaced by Asn
Descriptor: Glycogenin-1, SULFATE ION
Authors:Hurley, T.D, Stout, S.L, Miner, E, Zhou, J, Roach, P.J.
Deposit date:2005-04-13
Release date:2005-04-26
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.98 Å)
Cite:Requirements for catalysis in mammalian glycogenin.
J.Biol.Chem., 280, 2005
1ZLM
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BU of 1zlm by Molmil
Crystal structure of the SH3 domain of human osteoclast stimulating factor
Descriptor: Osteoclast stimulating factor 1
Authors:Chen, L, Wang, Y, Wells, D, Toh, D, Harold, H, Zhou, J, DiGiammarino, E, Meehan, E.J.
Deposit date:2005-05-06
Release date:2006-05-16
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (1.07 Å)
Cite:Structure of the SH3 domain of human osteoclast-stimulating factor at atomic resolution.
Acta Crystallogr.,Sect.F, 62, 2006
4FTW
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BU of 4ftw by Molmil
Crystal structure of a carboxyl esterase N110C/L145H at 2.3 angstrom resolution
Descriptor: 3-CYCLOHEXYLPROPYL 4-O-ALPHA-D-GLUCOPYRANOSYL-BETA-D-GLUCOPYRANOSIDE, CHLORIDE ION, PIPERAZINE-N,N'-BIS(2-ETHANESULFONIC ACID), ...
Authors:Wu, L, Ma, J, Zhou, J, Yu, H.
Deposit date:2012-06-28
Release date:2012-10-03
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Enhanced enantioselectivity of a carboxyl esterase from Rhodobacter sphaeroides by directed evolution.
Appl.Microbiol.Biotechnol., 97, 2013
5KPO
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BU of 5kpo by Molmil
Structure of human PARP1 catalytic domain bound to a quinazoline-2,4(1H,3H)-dione inhibitor
Descriptor: 1-[[3-(4-ethyl-3-oxidanylidene-piperazin-1-yl)carbonyl-4-fluoranyl-phenyl]methyl]quinazoline-2,4-dione, Poly [ADP-ribose] polymerase 1
Authors:Cao, R, Wang, Y.L, Zhou, J, Yao, H.P, Huang, N, Xu, B.L.
Deposit date:2016-07-05
Release date:2016-12-21
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Structure of human PARP1 catalytic domain bound to a quinazoline-2,4(1H,3H)-dione inhibitor
To Be Published

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