1ATP
 
 | | 2.2 angstrom refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MNATP and a peptide inhibitor | | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, PEPTIDE INHIBITOR PKI(5-24), ... | | 著者 | Zheng, J, Trafny, E.A, Knighton, D.R, Xuong, N.-H, Taylor, S.S, Teneyck, L.F, Sowadski, J.M. | | 登録日 | 1993-01-08 | | 公開日 | 1993-04-15 | | 最終更新日 | 2019-08-14 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | 2.2 A refined crystal structure of the catalytic subunit of cAMP-dependent protein kinase complexed with MnATP and a peptide inhibitor.
Acta Crystallogr.,Sect.D, 49, 1993
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1CMK
 | | CRYSTAL STRUCTURES OF THE MYRISTYLATED CATALYTIC SUBUNIT OF CAMP-DEPENDENT PROTEIN KINASE REVEAL OPEN AND CLOSED CONFORMATIONS | | 分子名称: | IODIDE ION, MYRISTIC ACID, cAMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNIT, ... | | 著者 | Zheng, J, Knighton, D.R, Xuong, N.-H, Taylor, S.S, Sowadski, J.M, Ten Eyck, L.F. | | 登録日 | 1993-11-18 | | 公開日 | 1994-05-31 | | 最終更新日 | 2012-07-18 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Crystal structures of the myristylated catalytic subunit of cAMP-dependent protein kinase reveal open and closed conformations.
Protein Sci., 2, 1993
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1AWE
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5LVX
 | | Crystal structure of glucocerebrosidase with an inhibitory quinazoline modulator | | 分子名称: | 11-[(2~{R})-2-[(2-pyridin-3-ylquinazolin-4-yl)amino]-2,3-dihydro-1~{H}-inden-5-yl]undec-10-ynoic acid, 11-[(2~{S})-2-[(2-pyridin-3-ylquinazolin-4-yl)amino]-2,3-dihydro-1~{H}-inden-5-yl]undec-10-ynoic acid, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Zheng, J, Chen, L, Skinner, O.S, Lansbury, P, Skerlj, R, Mrosek, M, Heunisch, U, Krapp, S, Weigand, S, Charrow, J, Schwake, M, Kelleher, N.L, Silverman, R.B, Krainc, D. | | 登録日 | 2016-09-14 | | 公開日 | 2017-10-25 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | beta-Glucocerebrosidase Modulators Promote Dimerization of beta-Glucocerebrosidase and Reveal an Allosteric Binding Site.
J. Am. Chem. Soc., 140, 2018
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4DIF
 | | Structure of A1-type ketoreductase | | 分子名称: | AmphB, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Zheng, J, Keatinge-Clay, A.T. | | 登録日 | 2012-01-30 | | 公開日 | 2013-02-13 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.521 Å) | | 主引用文献 | Structure and mutagenesis of A2-type ketoreductase from modular polyketide synthase reveals insights into stereospecificity
To be Published
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1ZYL
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1U5W
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4XXB
 | | Crystal structure of human MDM2-RPL11 | | 分子名称: | 60S ribosomal protein L11, BETA-MERCAPTOETHANOL, E3 ubiquitin-protein ligase Mdm2, ... | | 著者 | Zheng, J, Chen, Z. | | 登録日 | 2015-01-30 | | 公開日 | 2015-08-12 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structure of human MDM2 complexed with RPL11 reveals the molecular basis of p53 activation
Genes Dev., 29, 2015
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7VW9
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7VWA
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7VW8
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3LCB
 | | The crystal structure of isocitrate dehydrogenase kinase/phosphatase in complex with its substrate, isocitrate dehydrogenase, from Escherichia coli. | | 分子名称: | ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, Isocitrate dehydrogenase [NADP], ... | | 著者 | Zheng, J, Jia, Z. | | 登録日 | 2010-01-10 | | 公開日 | 2010-04-21 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structure of the bifunctional isocitrate dehydrogenase kinase/phosphatase.
Nature, 465, 2010
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3FRQ
 | | Structure of the macrolide biosensor protein, MphR(A), with erythromcyin | | 分子名称: | CHLORIDE ION, ERYTHROMYCIN A, GLYCEROL, ... | | 著者 | Zheng, J, Sagar, V, Smolinsky, A, Bourke, C, LaRonde-LeBlanc, N, Cropp, T.A. | | 登録日 | 2009-01-08 | | 公開日 | 2009-03-24 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.76 Å) | | 主引用文献 | Structure and function of the macrolide biosensor protein, MphR(A), with and without erythromycin
J.Mol.Biol., 387, 2009
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3G56
 | | Structure of the macrolide biosensor protein, MphR(A) | | 分子名称: | 1,2-ETHANEDIOL, GLYCEROL, Regulator of macrolide 2'-phosphotransferase I | | 著者 | Zheng, J, Sagar, V, Smolinsky, A, Bourke, C, LaRonde-LeBlanc, N, Cropp, T.A. | | 登録日 | 2009-02-04 | | 公開日 | 2009-03-03 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Structure and function of the macrolide biosensor protein, MphR(A), with and without erythromycin
J.Mol.Biol., 387, 2009
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3EPS
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3LC6
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4P0U
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4PT1
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3MJS
 | | Structure of A-type Ketoreductases from Modular Polyketide Synthase | | 分子名称: | (2S)-2-hydroxybutanedioic acid, AmphB, D-MALATE, ... | | 著者 | Zheng, J, Taylor, C.A, Piasecki, S.K, Keatinge-Clay, A.T. | | 登録日 | 2010-04-13 | | 公開日 | 2010-08-18 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structural and Functional Analysis of A-Type Ketoreductases from the Amphotericin Modular Polyketide Synthase.
Structure, 18, 2010
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3MJT
 | | Structure of A-type Ketoreductases from Modular Polyketide Synthase | | 分子名称: | AmphB, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Zheng, J, Taylor, C.A, Piasecki, S.K, Keatinge-Clay, A.T. | | 登録日 | 2010-04-13 | | 公開日 | 2010-08-18 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structural and Functional Analysis of A-Type Ketoreductases from the Amphotericin Modular Polyketide Synthase.
Structure, 18, 2010
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3MJC
 | | Structure of A-type Ketoreductases from Modular Polyketide Synthase | | 分子名称: | AmphB, GLYCEROL | | 著者 | Zheng, J, Taylor, C.A, Piasecki, S.K, Keatinge-Clay, A.T. | | 登録日 | 2010-04-12 | | 公開日 | 2010-08-18 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | | 主引用文献 | Structural and Functional Analysis of A-Type Ketoreductases from the Amphotericin Modular Polyketide Synthase.
Structure, 18, 2010
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3MJV
 | | Structure of A-type Ketoreductases from Modular Polyketide Synthase | | 分子名称: | AmphB, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Zheng, J, Taylor, C.A, Piasecki, S.K, Keatinge-Clay, A.T. | | 登録日 | 2010-04-13 | | 公開日 | 2010-08-18 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Structural and Functional Analysis of A-Type Ketoreductases from the Amphotericin Modular Polyketide Synthase.
Structure, 18, 2010
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3MJE
 | | Structure of A-type Ketoreductases from Modular Polyketide Synthase | | 分子名称: | AmphB, GLYCEROL, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE | | 著者 | Zheng, J, Taylor, C.A, Piasecki, S.K, Keatinge-Clay, A.T. | | 登録日 | 2010-04-12 | | 公開日 | 2010-08-18 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1.36 Å) | | 主引用文献 | Structural and Functional Analysis of A-Type Ketoreductases from the Amphotericin Modular Polyketide Synthase.
Structure, 18, 2010
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4IMP
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3QP9
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