3B6C
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8ENK
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8A4T
| crystal structures of diastereomer (S,S,S)-13b (13b-K) in complex with the SARS-CoV-2 Mpro | Descriptor: | 3C-like proteinase nsp5, CHLORIDE ION, ~{tert}-butyl ~{N}-[1-[(2~{S})-3-cyclopropyl-1-oxidanylidene-1-[[(2~{S},3~{R})-3-oxidanyl-4-oxidanylidene-1-[(3~{S})-2-oxidanylidenepyrrolidin-3-yl]-4-[(phenylmethyl)amino]butan-2-yl]amino]propan-2-yl]-2-oxidanylidene-pyridin-3-yl]carbamate | Authors: | Ibrahim, M, Hilgenfeld, R, Zhang, L. | Deposit date: | 2022-06-13 | Release date: | 2022-10-12 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Diastereomeric Resolution Yields Highly Potent Inhibitor of SARS-CoV-2 Main Protease. J.Med.Chem., 65, 2022
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6UJI
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5X9C
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5X9B
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8D0A
| Crystal structure of human USP30 in complex with a covalent inhibitor 829 and a Fab | Descriptor: | Ubiquitin carboxyl-terminal hydrolase 30, ZINC ION, mouse anti-huUSP30 Fab heavy chain, ... | Authors: | Song, X, Butler, J, Li, C, Zhang, K, Zhang, D, Hao, Y. | Deposit date: | 2022-05-25 | Release date: | 2023-02-01 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (3.19 Å) | Cite: | TBD To Be Published
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8T1O
| AP2 bound to MSP2N2 nanodisc with Tgn38 cargo peptide; composite map | Descriptor: | AP-2 complex subunit alpha-2, AP-2 complex subunit beta, AP-2 complex subunit mu, ... | Authors: | Baker, R.W, Cannon, K.S, Reta, S. | Deposit date: | 2023-06-02 | Release date: | 2023-07-12 | Last modified: | 2023-07-19 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Lipid nanodiscs as a template for high-resolution cryo-EM structures of peripheral membrane proteins. J.Struct.Biol., 215, 2023
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8A4Q
| crystal structures of diastereomer (R,S,S)-13b (13b-H) in complex with the SARS-CoV-2 Mpro. | Descriptor: | 3C-like proteinase nsp5, CHLORIDE ION, DIMETHYL SULFOXIDE, ... | Authors: | Ibrahim, M, Hilgenfeld, R, Zhang, L. | Deposit date: | 2022-06-13 | Release date: | 2022-10-12 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Diastereomeric Resolution Yields Highly Potent Inhibitor of SARS-CoV-2 Main Protease. J.Med.Chem., 65, 2022
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2HW2
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4DZ1
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6OFP
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7W75
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7W76
| Crystal structure of the K. lactis Bre1 RBD in complex with Rad6, crystal form II | Descriptor: | E3 ubiquitin-protein ligase BRE1, GLYCEROL, SULFATE ION, ... | Authors: | Shi, M, Zhao, J, Xiang, S. | Deposit date: | 2021-12-03 | Release date: | 2023-03-29 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Structural basis for the Rad6 activation by the Bre1 N-terminal domain. Elife, 12, 2023
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7K58
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2OPT
| Crystal Structure of Apo ActR from Streptomyces coelicolor. | Descriptor: | ActII protein | Authors: | Willems, A.R, Junop, M.S. | Deposit date: | 2007-01-30 | Release date: | 2008-02-05 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Crystal structures of the Streptomyces coelicolor TetR-like protein ActR alone and in complex with actinorhodin or the actinorhodin biosynthetic precursor (S)-DNPA. J.Mol.Biol., 376, 2008
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8K8J
| Cannabinoid Receptor 1 bound to Fenofibrate coupling MiniGsq and Nb35 Complex | Descriptor: | Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, Guanine nucleotide-binding protein G(s) subunit alpha isoforms short, ... | Authors: | Tang, W.Q, Wang, T.X, Li, F.H, Wang, J.Y. | Deposit date: | 2023-07-30 | Release date: | 2024-02-14 | Last modified: | 2024-04-24 | Method: | ELECTRON MICROSCOPY (2.88 Å) | Cite: | Fenofibrate Recognition and G q Protein Coupling Mechanisms of the Human Cannabinoid Receptor CB1. Adv Sci, 11, 2024
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6TZW
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6TYL
| Crystal structure of mammalian Ric-8A:Galpha(i):nanobody complex | Descriptor: | Guanine nucleotide-binding protein G(i) subunit alpha-1, Nanobody A, Nanobody B, ... | Authors: | Mou, T.C, McClelland, L, Yates-Hansen, C, Sprang, S.R. | Deposit date: | 2019-08-09 | Release date: | 2020-03-11 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Structure of the G protein chaperone and guanine nucleotide exchange factor Ric-8A bound to G alpha i1. Nat Commun, 11, 2020
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3F7O
| Crystal structure of Cuticle-Degrading Protease from Paecilomyces lilacinus (PL646) | Descriptor: | (MSU)(ALA)(ALA)(PRO)(VAL), CALCIUM ION, Serine protease | Authors: | Liang, L, Lou, Z, Meng, Z, Rao, Z, Zhang, K. | Deposit date: | 2008-11-10 | Release date: | 2009-11-17 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The crystal structures of two cuticle-degrading proteases from nematophagous fungi and their contribution to infection against nematodes. Faseb J., 24, 2010
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3F7M
| Crystal structure of apo Cuticle-Degrading Protease (ver112) from Verticillium psalliotae | Descriptor: | Alkaline serine protease ver112 | Authors: | Liang, L, Lou, Z, Ye, F, Meng, Z, Rao, Z, Zhang, K. | Deposit date: | 2008-11-09 | Release date: | 2009-11-17 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The crystal structures of two cuticle-degrading proteases from nematophagous fungi and their contribution to infection against nematodes. Faseb J., 24, 2010
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7N9Z
| E. coli cytochrome bo3 in MSP nanodisc | Descriptor: | 1,2-DIPALMITOYL-PHOSPHATIDYL-GLYCEROLE, 1,2-Distearoyl-sn-glycerophosphoethanolamine, CARDIOLIPIN, ... | Authors: | Vallese, F, Clarke, O.B. | Deposit date: | 2021-06-19 | Release date: | 2021-09-01 | Method: | ELECTRON MICROSCOPY (2.19 Å) | Cite: | Cryo-EM structures of Escherichia coli cytochrome bo 3 reveal bound phospholipids and ubiquinone-8 in a dynamic substrate binding site. Proc.Natl.Acad.Sci.USA, 118, 2021
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8GNA
| Structure of the SbCas7-11-crRNA-NTR complex | Descriptor: | RAMP superfamily protein, RNA (32-MER), RNA (5'-R(P*GP*GP*GP*GP*CP*AP*GP*AP*AP*AP*AP*UP*UP*GP*GP*GP*U)-3'), ... | Authors: | Yu, G, Wang, X, Deng, Z, Zhang, H. | Deposit date: | 2022-08-23 | Release date: | 2023-01-18 | Method: | ELECTRON MICROSCOPY (2.8 Å) | Cite: | Target RNA-guided protease activity in type III-E CRISPR-Cas system. Nucleic Acids Res., 50, 2022
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8GU6
| Structure of the SbCas7-11-crRNA-NTR-Csx29 complex | Descriptor: | CHAT domain protein, RAMP superfamily protein, RNA (33-MER), ... | Authors: | Yu, G, Wang, X, Deng, Z, Zhang, H. | Deposit date: | 2022-09-10 | Release date: | 2023-01-18 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Target RNA-guided protease activity in type III-E CRISPR-Cas system. Nucleic Acids Res., 50, 2022
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8ITE
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