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8GP6
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BU of 8gp6 by Molmil
Structure of the vaccinia virus A16/G9 sub-complex from the orthopoxvirus entry-fusion complex
Descriptor: GLYCEROL, Myristoylated protein G9, Virion membrane protein A16
Authors:Lu, G.W, Yang, F.L, Lin, S.
Deposit date:2022-08-25
Release date:2023-05-17
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural basis of poxvirus A16/G9 binding for sub-complex formation.
Emerg Microbes Infect, 12, 2023
7V1Y
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BU of 7v1y by Molmil
Serine beta-lactamase-like protein LACTB in complex with inhibitor
Descriptor: ALA-ALA-B3S, Serine beta-lactamase-like protein LACTB, mitochondrial
Authors:Zhang, M.H, Yang, M.J.
Deposit date:2021-08-07
Release date:2022-02-16
Last modified:2023-11-15
Method:ELECTRON MICROSCOPY (2.82 Å)
Cite:Structural basis for the catalytic activity of filamentous human serine beta-lactamase-like protein LACTB.
Structure, 30, 2022
7V1Z
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BU of 7v1z by Molmil
human Serine beta-lactamase-like protein LACTB
Descriptor: Serine beta-lactamase-like protein LACTB, mitochondrial
Authors:Zhang, M.H, Yang, M.J.
Deposit date:2021-08-07
Release date:2022-02-16
Last modified:2023-03-01
Method:ELECTRON MICROSCOPY (2.98 Å)
Cite:Structural basis for the catalytic activity of filamentous human serine beta-lactamase-like protein LACTB.
Structure, 30, 2022
7V21
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BU of 7v21 by Molmil
human Serine beta-lactamase-like protein LACTB truncation variant
Descriptor: Serine beta-lactamase-like protein LACTB, mitochondrial
Authors:Zhang, M.H, Yang, M.J.
Deposit date:2021-08-07
Release date:2022-02-16
Last modified:2023-03-01
Method:ELECTRON MICROSCOPY (3.08 Å)
Cite:Structural basis for the catalytic activity of filamentous human serine beta-lactamase-like protein LACTB.
Structure, 30, 2022
8HB2
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BU of 8hb2 by Molmil
Crystal structure of Caenorhabditis elegans NMAD-1 in complex with ligand II
Descriptor: 2-OXOGLUTARIC ACID, DNA N6-methyl adenine demethylase, MANGANESE (II) ION
Authors:Shang, G, Chen, Z.
Deposit date:2022-10-27
Release date:2024-02-07
Method:X-RAY DIFFRACTION (3.06 Å)
Cite:Structural Basis of Nucleic Acid Recognition and 6mA Demethylation by Caenorhabditis elegans NMAD-1A.
Int J Mol Sci, 25, 2024
8HAZ
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BU of 8haz by Molmil
Crystal structure of Caenorhabditis elegans NMAD-1 in complex with ligand I
Descriptor: DNA N6-methyl adenine demethylase, SULFATE ION
Authors:Shang, G, Chen, Z.
Deposit date:2022-10-27
Release date:2024-02-07
Method:X-RAY DIFFRACTION (2.66 Å)
Cite:Structural Basis of Nucleic Acid Recognition and 6mA Demethylation by Caenorhabditis elegans NMAD-1A.
Int J Mol Sci, 25, 2024
8HBB
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BU of 8hbb by Molmil
Crystal structure of Caenorhabditis elegans NMAD-1 in complex with ligand III
Descriptor: CHLORIDE ION, DNA N6-methyl adenine demethylase, MANGANESE (II) ION
Authors:Shang, G, Chen, Z.
Deposit date:2022-10-27
Release date:2024-02-07
Method:X-RAY DIFFRACTION (3.09 Å)
Cite:Structural Basis of Nucleic Acid Recognition and 6mA Demethylation by Caenorhabditis elegans NMAD-1A.
Int J Mol Sci, 25, 2024
8GYX
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BU of 8gyx by Molmil
Cryo-EM structure of human CEPT1
Descriptor: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, Choline/ethanolaminephosphotransferase 1, MAGNESIUM ION
Authors:Qian, H.W, Wang, Z.H.
Deposit date:2022-09-24
Release date:2023-03-22
Last modified:2023-10-04
Method:ELECTRON MICROSCOPY (3.7 Å)
Cite:Structural basis for catalysis of human choline/ethanolamine phosphotransferase 1.
Nat Commun, 14, 2023
8GYW
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BU of 8gyw by Molmil
Cryo-EM structure of human CEPT1 complexed with CDP-choline
Descriptor: Choline/ethanolaminephosphotransferase 1, MAGNESIUM ION, [2-CYTIDYLATE-O'-PHOSPHONYLOXYL]-ETHYL-TRIMETHYL-AMMONIUM
Authors:Qian, H.W, Wang, Z.H.
Deposit date:2022-09-24
Release date:2023-03-22
Last modified:2023-10-04
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural basis for catalysis of human choline/ethanolamine phosphotransferase 1.
Nat Commun, 14, 2023
1P5T
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BU of 1p5t by Molmil
Crystal Structure of Dok1 PTB Domain
Descriptor: Docking protein 1
Authors:Shi, N, Ye, S, Liu, Y, Zhou, W, Ding, Y, Lou, Z, Qiang, B, Yuan, J, Rao, Z.
Deposit date:2003-04-28
Release date:2004-02-17
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural Basis for the Specific Recognition of RET by the Dok1 Phosphotyrosine Binding Domain
J.BIOL.CHEM., 279, 2004
8V7O
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BU of 8v7o by Molmil
Fab fragment of human mAb #58 in complex with computationally optimized broadly reactive H1 influenza hemagglutinin X6
Descriptor: #58 heavy chain, #58 light chain, Hemagglutinin
Authors:Nagashima, K.A, Mousa, J.J.
Deposit date:2023-12-04
Release date:2024-04-10
Method:ELECTRON MICROSCOPY (3.57 Å)
Cite:Structural basis for the broad antigenicity of the computationally optimized influenza hemagglutinin X6
To Be Published
6JLC
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BU of 6jlc by Molmil
Structure determination of CAMP factor of Mobiluncus curtisii and insight into structural dynamics
Descriptor: ACETATE ION, CAMP factor
Authors:Jin, T.C, Zeng, W.H.
Deposit date:2019-03-04
Release date:2019-12-04
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.847 Å)
Cite:Structure determination of CAMP factor of Mobiluncus curtisii and insights into structural dynamics.
Int.J.Biol.Macromol., 150, 2020
4OLS
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BU of 4ols by Molmil
The amidase-2 domain of LysGH15
Descriptor: Endolysin, FE (III) ION, MAGNESIUM ION, ...
Authors:Gu, J, Ouyang, S, Liu, Z.J, Han, W.
Deposit date:2014-01-24
Release date:2014-06-04
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Structural and biochemical characterization reveals LysGH15 as an unprecedented "EF-hand-like" calcium-binding phage lysin.
Plos Pathog., 10, 2014
4OLK
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BU of 4olk by Molmil
The CHAP domain of LysGH15
Descriptor: 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CALCIUM ION, Endolysin
Authors:Gu, J, Ouyang, S, Liu, Z.J, Han, W.
Deposit date:2014-01-24
Release date:2014-05-28
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.694 Å)
Cite:Structural and biochemical characterization reveals LysGH15 as an unprecedented "EF-hand-like" calcium-binding phage lysin.
Plos Pathog., 10, 2014
6N7E
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BU of 6n7e by Molmil
Crystal structure of the cytosolic domain of human CNNM2 in complex with AMP-PNP and Mg2+
Descriptor: MAGNESIUM ION, Metal transporter CNNM2,Metal transporter CNNM2, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER
Authors:Chen, Y.S, Gehring, K.
Deposit date:2018-11-27
Release date:2019-12-04
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Mg2+-ATP Sensing in CNNM, a Putative Magnesium Transporter.
Structure, 28, 2020
5K22
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BU of 5k22 by Molmil
Crystal structure of the complex between human PRL-2 phosphatase in reduced state and Bateman domain of human CNNM3
Descriptor: Metal transporter CNNM3, Protein tyrosine phosphatase type IVA 2
Authors:Kozlov, G, Wu, H, Gehring, K.
Deposit date:2016-05-18
Release date:2016-10-12
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3 Å)
Cite:Phosphocysteine in the PRL-CNNM pathway mediates magnesium homeostasis.
EMBO Rep., 17, 2016
2MK5
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BU of 2mk5 by Molmil
Solution structure of a protein domain
Descriptor: Endolysin
Authors:Feng, Y, Gu, J.
Deposit date:2014-01-24
Release date:2014-05-28
Last modified:2019-12-18
Method:SOLUTION NMR
Cite:Structural and biochemical characterization reveals LysGH15 as an unprecedented "EF-hand-like" calcium-binding phage lysin.
Plos Pathog., 10, 2014
6PAV
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BU of 6pav by Molmil
Structure of Human NMT1 with products CoA and myristoyl-lysine peptide with acetylated N-terminus
Descriptor: ARF6 peptide, COENZYME A, GLYCEROL, ...
Authors:Price, I.R, Lin, H.
Deposit date:2019-06-12
Release date:2020-03-11
Method:X-RAY DIFFRACTION (2.52 Å)
Cite:NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle.
Nat Commun, 11, 2020
6PAU
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BU of 6pau by Molmil
Structure of Human NMT2 with myristoyl-lysine peptide and CoA products
Descriptor: 4'-diphospho pantetheine, Arf6 peptide, GLYCEROL, ...
Authors:Price, I.R, Lin, H.
Deposit date:2019-06-11
Release date:2020-03-11
Last modified:2023-10-11
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle.
Nat Commun, 11, 2020
5NFO
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BU of 5nfo by Molmil
Human JMJD7 in complex with Mn and 2OG in the P21212 form
Descriptor: 2-OXOGLUTARIC ACID, GLYCEROL, JmjC domain-containing protein 7, ...
Authors:Chowdhury, R, Markolovic, S, Schofield, C.J.
Deposit date:2017-03-14
Release date:2018-03-14
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.173 Å)
Cite:(3S)-Lysyl hydroxylation of TRAFAC GTPases is catalyzed by the human Jumonji-C oxygenase JMJD7.
To Be Published
3LZ6
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BU of 3lz6 by Molmil
Guinea Pig 11beta hydroxysteroid dehydrogenase with PF-877423
Descriptor: Corticosteroid 11-beta-dehydrogenase isozyme 1, N-adamantan-2-yl-1-ethyl-D-prolinamide, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Pauly, T.A.
Deposit date:2010-03-01
Release date:2011-05-04
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.84 Å)
Cite:The development and SAR of pyrrolidine carboxamide 11beta-HSD1 inhibitors.
Bioorg.Med.Chem.Lett., 20, 2010
6IEC
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BU of 6iec by Molmil
Structure of RVFV Gn and human monoclonal antibody R17
Descriptor: NSmGnGc, R17 H chain, R17 L chain
Authors:Wang, Q.H, Wu, Y, Gao, F, Qi, J.X, Gao, G.F.
Deposit date:2018-09-13
Release date:2019-04-10
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (3.2 Å)
Cite:Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus.
Nat Microbiol, 4, 2019
6IEA
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BU of 6iea by Molmil
Structure of RVFV Gn and human monoclonal antibody R13
Descriptor: DI(HYDROXYETHYL)ETHER, GLYCEROL, NSmGnGc, ...
Authors:Wang, Q.H, Wu, Y, Gao, F, Qi, J.X, Gao, G.F.
Deposit date:2018-09-13
Release date:2019-04-10
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (2 Å)
Cite:Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus.
Nat Microbiol, 4, 2019
6IEK
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BU of 6iek by Molmil
Structure of RVFV Gn and human monoclonal antibody R12
Descriptor: Heavy chain of Fab R12, Light chain of Fab R12, NSmGnGc
Authors:Wang, Q.H, Wu, Y, Gao, F, Qi, J.X, Gao, G.F.
Deposit date:2018-09-14
Release date:2019-04-10
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus.
Nat Microbiol, 4, 2019
6IEB
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BU of 6ieb by Molmil
Structure of RVFV Gn and human monoclonal antibody R15
Descriptor: NSmGnGc, R15 H chain, R15 L chain
Authors:Wang, Q.H, Wu, Y, Gao, F, Qi, J.X, Gao, G.F.
Deposit date:2018-09-13
Release date:2019-04-10
Last modified:2019-07-10
Method:X-RAY DIFFRACTION (2.409 Å)
Cite:Neutralization mechanism of human monoclonal antibodies against Rift Valley fever virus.
Nat Microbiol, 4, 2019

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