6PAV

Structure of Human NMT1 with products CoA and myristoyl-lysine peptide with acetylated N-terminus

Summary for 6PAV

• Entry DOI: 10.2210/pdb6pav/pdb
• Descriptor: Glycylpeptide N-tetradecanoyltransferase 1, acetyl-Arf6 peptide, ARF6 peptide, ... (7 entities in total)
• Functional Keywords: lysine, myristoyl, myristoylation, n-myristoyl transferase, transferase
• Biological source: Homo sapiens (Human); More
• Total number of polymer chains: 4
• Total formula weight: 94437.48

Authors

Price, I.R.,Lin, H. (deposition date: 2019-06-12, release date: 2020-03-11)

• Primary citation: Kosciuk, T.,Price, I.R.,Zhang, X.,Zhu, C.,Johnson, K.N.,Zhang, S.,Halaby, S.L.,Komaniecki, G.P.,Yang, M.,DeHart, C.J.,Thomas, P.M.,Kelleher, N.L.,Christopher Fromme, J.,Lin, H.; NMT1 and NMT2 are lysine myristoyltransferases regulating the ARF6 GTPase cycle.; Nat Commun, 11:1067-1067, 2020; PubMed: 32103017; DOI: 10.1038/s41467-020-14893-x

Experimental method

X-RAY DIFFRACTION (2.52 Å)