1GN4
| H145E mutant of Mycobacterium tuberculosis iron-superoxide dismutase. | Descriptor: | MANGANESE (II) ION, SUPEROXIDE DISMUTASE | Authors: | Bunting, K.A, Cooper, J.B, Badasso, M.O, Tickle, I.J, Newton, M, Wood, S.P, Zhang, Y, Young, D.B. | Deposit date: | 2001-10-02 | Release date: | 2001-10-05 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Engineering a Change in the Metal-Ion Specificity of the Iron-Depedent Superoxide Dismutase from Mycobacterium Tuberculosis. X-Ray Structure Analysis of Site-Directed Mutants Eur.J.Biochem., 251, 1998
|
|
1GJP
| SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH 4-OXOSEBACIC ACID | Descriptor: | 4-OXODECANEDIOIC ACID, 5-AMINOLAEVULINIC ACID DEHYDRATASE, ZINC ION | Authors: | Erskine, P.T, Coates, L, Newbold, R, Brindley, A.A, Wood, S.P, Warren, M.J, Cooper, J.B, Shoolingin-Jordan, P.M, Neier, R. | Deposit date: | 2001-08-01 | Release date: | 2001-08-02 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Two Diacid Inhibitors FEBS Lett., 503, 2001
|
|
1GN3
| H145Q mutant of Mycobacterium tuberculosis iron-superoxide dismutase. | Descriptor: | FE (III) ION, SUPEROXIDE DISMUTASE | Authors: | Bunting, K.A, Cooper, J.B, Badasso, M.O, Tickle, I.J, Newton, M, Wood, S.P, Zhang, Y, Young, D.B. | Deposit date: | 2001-10-02 | Release date: | 2001-10-05 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (4 Å) | Cite: | Engineering a Change in the Metal-Ion Specificity of the Iron-Depedent Superoxide Dismutase from Mycobacterium Tuberculosis. X-Ray Structure Analysis of Site-Directed Mutants. Eur.J.Biochem., 251, 1998
|
|
1GVW
| Endothiapepsin complex with PD-130,328 | Descriptor: | ENDOTHIAPEPSIN, N-(tert-butoxycarbonyl)-L-phenylalanyl-N-{(1S)-1-[(R)-hydroxy(2-{[(2S)-2-methylbutyl]amino}-2-oxoethyl)phosphoryl]-3-methylbutyl}-3-(1H-imidazol-3-ium-4-yl)-L-alaninamide, SULFATE ION | Authors: | Coates, L, Erskine, P.T, Crump, M.P, Wood, S.P, Cooper, J.B. | Deposit date: | 2002-02-27 | Release date: | 2002-07-04 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Five Atomic Resolution Structures of Endothiapepsin Inhibitor Complexes: Implications for the Aspartic Proteinase Mechanism J.Mol.Biol., 318, 2002
|
|
1GVV
| Five Atomic Resolution Structures of Endothiapepsin Inhibitor Complexes; implications for the Aspartic Proteinase Mechanism | Descriptor: | ENDOTHIAPEPSIN, N-[(5S,9S,10S,13S)-9-hydroxy-5,10-bis(2-methylpropyl)-4,7,12,16-tetraoxo-3,6,11,17-tetraazabicyclo[17.3.1]tricosa-1(23),19,21-trien-13-yl]-3-(naphthalen-1-yl)-2-(naphthalen-1-ylmethyl)propanamide, SULFATE ION | Authors: | Coates, L, Erskine, P.T, Crump, M.P, Wood, S.P, Cooper, J.B. | Deposit date: | 2002-02-27 | Release date: | 2002-07-04 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Five Atomic Resolution Structures of Endothiapepsin Inhibitor Complexes: Implications for the Aspartic Proteinase Mechanism J.Mol.Biol., 318, 2002
|
|
1GVT
| Endothiapepsin complex with CP-80,794 | Descriptor: | ENDOTHIAPEPSIN, N-(morpholin-4-ylcarbonyl)-L-phenylalanyl-N-[(1R,2S)-1-(cyclohexylmethyl)-2-hydroxy-3-(1-methylethoxy)-3-oxopropyl]-S-methyl-L-cysteinamide, SULFATE ION | Authors: | Coates, L, Erskine, P.T, Crump, M.P, Wood, S.P, Cooper, J.B. | Deposit date: | 2002-02-27 | Release date: | 2002-07-04 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (0.98 Å) | Cite: | Five Atomic Resolution Structures of Endothiapepsin Inhibitor Complexes: Implications for the Aspartic Proteinase Mechanism J.Mol.Biol., 318, 2002
|
|
1GVU
| Endothiapepsin complex with H189 | Descriptor: | ENDOTHIAPEPSIN, INHIBITOR, H189, ... | Authors: | Coates, L, Erskine, P.T, Crump, M.P, Wood, S.P, Cooper, J.B. | Deposit date: | 2002-02-27 | Release date: | 2002-07-04 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (0.94 Å) | Cite: | Five Atomic Resolution Structures of Endothiapepsin Inhibitor Complexes: Implications for the Aspartic Proteinase Mechanism J.Mol.Biol., 318, 2002
|
|
3M1O
| |
4LP9
| Endothiapepsin complexed with Phe-reduced-Tyr peptide. | Descriptor: | Endothiapepsin, GLYCEROL, SULFATE ION, ... | Authors: | Guo, J, Cooper, J.B, Wood, S.P. | Deposit date: | 2013-07-15 | Release date: | 2014-01-15 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | The structure of endothiapepsin complexed with a Phe-Tyr reduced-bond inhibitor at 1.35 angstrom resolution. Acta Crystallogr F Struct Biol Commun, 70, 2014
|
|
3NFT
| Near-atomic resolution analysis of BipD- A component of the type-III secretion system of Burkholderia pseudomallei | Descriptor: | Translocator protein bipD | Authors: | Pal, M, Erskine, P.T, Gill, R.S, Wood, S.P, Cooper, J.B. | Deposit date: | 2010-06-10 | Release date: | 2010-07-14 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Near-atomic resolution analysis of BipD, a component of the type III secretion system of Burkholderia pseudomallei. Acta Crystallogr.,Sect.F, 66, 2010
|
|
4MLV
| Crystal Structure of Bacillus megaterium porphobilinogen deaminase | Descriptor: | 3-[(5S)-5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-2-oxo-2,5-dihydro-1H-pyrrol-3-yl]propanoic acid, 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, ACETIC ACID, ... | Authors: | Azim, N, Deery, E, Warren, M.J, Erskine, P, Cooper, J.B, Coker, A, Wood, S.P, Akhtar, M. | Deposit date: | 2013-09-06 | Release date: | 2014-04-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.455 Å) | Cite: | Structural evidence for the partially oxidized dipyrromethene and dipyrromethanone forms of the cofactor of porphobilinogen deaminase: structures of the Bacillus megaterium enzyme at near-atomic resolution. Acta Crystallogr.,Sect.D, 70, 2014
|
|
4MRB
| Wild Type Human Transthyretin pH 7.5 | Descriptor: | CALCIUM ION, Transthyretin | Authors: | Chen, W.J, Wood, S.P. | Deposit date: | 2013-09-17 | Release date: | 2014-01-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.27 Å) | Cite: | Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4MLQ
| Crystal structure of Bacillus megaterium porphobilinogen deaminase | Descriptor: | 3-[(5S)-5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-2-oxo-2,5-dihydro-1H-pyrrol-3-yl]propanoic acid, 3-[5-{[3-(2-carboxyethyl)-4-(carboxymethyl)-5-methyl-1H-pyrrol-2-yl]methyl}-4-(carboxymethyl)-1H-pyrrol-3-yl]propanoic acid, ACETIC ACID, ... | Authors: | Azim, N, Deery, E, Warren, M.J, Erskine, P, Cooper, J.B, Coker, A, Wood, S.P, Akhtar, M. | Deposit date: | 2013-09-06 | Release date: | 2014-04-02 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Structural evidence for the partially oxidized dipyrromethene and dipyrromethanone forms of the cofactor of porphobilinogen deaminase: structures of the Bacillus megaterium enzyme at near-atomic resolution. Acta Crystallogr.,Sect.D, 70, 2014
|
|
4MRC
| Human Transthyretin Ser52Pro Mutant | Descriptor: | CALCIUM ION, Transthyretin | Authors: | Chen, W.J, Wood, S.P. | Deposit date: | 2013-09-17 | Release date: | 2014-01-08 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.54 Å) | Cite: | Proteolytic cleavage of Ser52Pro variant transthyretin triggers its amyloid fibrillogenesis. Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
4NDB
| X-ray structure of a mutant (T61D) of calexcitin - a neuronal calcium-signalling protein | Descriptor: | CALCIUM ION, Calexcitin | Authors: | Erskine, P.T, Fokas, A, Muriithi, C, Razzall, E, Bowyer, A, Findlow, I.S, Werner, J.M, Wallace, B.A, Wood, S.P, Cooper, J.B. | Deposit date: | 2013-10-25 | Release date: | 2014-10-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray, spectroscopic and normal-mode dynamics of calexcitin: structure-function studies of a neuronal calcium-signalling protein. Acta Crystallogr.,Sect.D, 71, 2015
|
|
4NDC
| X-ray structure of a mutant (T188D) of calexcitin - a neuronal calcium-signalling protein | Descriptor: | CALCIUM ION, Calexcitin | Authors: | Erskine, P.T, Fokas, A, Muriithi, C, Razzall, E, Bowyer, A, Findlow, I.S, Werner, J.M, Wallace, B.A, Wood, S.P, Cooper, J.B. | Deposit date: | 2013-10-25 | Release date: | 2014-10-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray, spectroscopic and normal-mode dynamics of calexcitin: structure-function studies of a neuronal calcium-signalling protein. Acta Crystallogr.,Sect.D, 71, 2015
|
|
4NDD
| X-ray structure of a double mutant of calexcitin - a neuronal calcium-signalling protein | Descriptor: | CALCIUM ION, Calexcitin | Authors: | Erskine, P.T, Fokas, A, Muriithi, C, Razzall, E, Bowyer, A, Findlow, I.S, Werner, J.M, Wallace, B.A, Wood, S.P, Cooper, J.B. | Deposit date: | 2013-10-25 | Release date: | 2014-10-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | X-ray, spectroscopic and normal-mode dynamics of calexcitin: structure-function studies of a neuronal calcium-signalling protein. Acta Crystallogr.,Sect.D, 71, 2015
|
|
4P9G
| Structure of the 2,4'-dihydroxyacetophenone dioxygenase from Alcaligenes sp. | Descriptor: | 2,4'-dihydroxyacetophenone dioxygenase, CARBONATE ION, FE (III) ION, ... | Authors: | Keegan, R, Lebedev, A, Erskine, P, Guo, J, Wood, S.P, Hopper, D.J, Cooper, J.B. | Deposit date: | 2014-04-03 | Release date: | 2014-09-10 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the 2,4'-dihydroxyacetophenone dioxygenase from Alcaligenes sp. 4HAP Acta Crystallogr.,Sect.D, 70, 2014
|
|
1GVX
| Endothiapepsin complexed with H256 | Descriptor: | ENDOTHIAPEPSIN, INHIBITOR H256, SULFATE ION | Authors: | Coates, L, Erskine, P.T, Crump, M.P, Wood, S.P, Cooper, J.B. | Deposit date: | 2002-02-27 | Release date: | 2002-07-04 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1 Å) | Cite: | Five Atomic Resolution Structures of Endothiapepsin Inhibitor Complexes: Implications for the Aspartic Proteinase Mechanism J.Mol.Biol., 318, 2002
|
|
1H7P
| SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH 4-KETO-5-AMINO-HEXANOIC (KAH) AT 1.64 A RESOLUTION | Descriptor: | 5-AMINO-4-HYDROXYHEXANOIC ACID, 5-AMINOLAEVULINIC ACID DEHYDRATASE, ZINC ION | Authors: | Erskine, P.T, Newbold, R, Brindley, A.A, Wood, S.P, Shoolingin-Jordan, P.M, Warren, M.J, Cooper, J.B. | Deposit date: | 2001-07-09 | Release date: | 2001-07-13 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.64 Å) | Cite: | The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Substrate and Three Inhibitors J.Mol.Biol., 312, 2001
|
|
1H4J
| Methylobacterium extorquens methanol dehydrogenase D303E mutant | Descriptor: | CALCIUM ION, Methanol dehydrogenase [cytochrome c] subunit 1, Methanol dehydrogenase [cytochrome c] subunit 2, ... | Authors: | Mohammed, F, Gill, R, Thompson, D, Cooper, J.B, Wood, S.P, Afolabi, P.R, Anthony, C. | Deposit date: | 2001-05-11 | Release date: | 2001-08-23 | Last modified: | 2018-09-19 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Site-Directed Mutagenesis and X-Ray Crystallography of the Pqq-Containing Quinoprotein Methanol Dehydrogenase and its Electron Acceptor, Cytochrome C(L)(,) Biochemistry, 40, 2001
|
|
1H7O
| SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH 5-AMINOLAEVULINIC ACID AT 1.7 A RESOLUTION | Descriptor: | 5-AMINOLAEVULINIC ACID DEHYDRATASE, DELTA-AMINO VALERIC ACID, ZINC ION | Authors: | Erskine, P.T, Newbold, R, Brindley, A.A, Wood, S.P, Shoolingin-Jordan, P.M, Warren, M.J, Cooper, J.B. | Deposit date: | 2001-07-09 | Release date: | 2001-07-10 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Substrate and Three Inhibitors J.Mol.Biol., 312, 2001
|
|
1GYK
| Serum Amyloid P Component co-crystallised with MOBDG at neutral pH | Descriptor: | CALCIUM ION, METHYL 4,6-O-[(1R)-1-CARBOXYETHYLIDENE]-BETA-D-GALACTOPYRANOSIDE, SERUM AMYLOID P-COMPONENT | Authors: | Thompson, D, Pepys, M.B, Tickle, I, Wood, S.P. | Deposit date: | 2002-04-25 | Release date: | 2003-05-22 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | The Structures of Crystalline Complexes of Human Serum Amyloid P Component with its Carbohydrate Ligand, the Cyclic Pyruvate Acetal of Galactose J.Mol.Biol., 320, 2002
|
|
1H7N
| SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH LAEVULINIC ACID AT 1.6 A RESOLUTION | Descriptor: | 5-AMINOLAEVULINIC ACID DEHYDRATASE, LAEVULINIC ACID, ZINC ION | Authors: | Erskine, P.T, Newbold, R, Brindley, A.A, Wood, S.P, Shoolingin-Jordan, P.M, Warren, M.J, Cooper, J.B. | Deposit date: | 2001-07-09 | Release date: | 2001-07-10 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Substrate and Three Inhibitors J.Mol.Biol., 312, 2001
|
|
1H7R
| SCHIFF-BASE COMPLEX OF YEAST 5-AMINOLAEVULINIC ACID DEHYDRATASE WITH SUCCINYLACETONE AT 2.0 A RESOLUTION. | Descriptor: | 4,6-DIOXOHEPTANOIC ACID, 5-AMINOLAEVULINIC ACID DEHYDRATASE, ZINC ION | Authors: | Erskine, P.T, Newbold, R, Brindley, A.A, Wood, S.P, Shoolingin-Jordan, P.M, Warren, M.J, Cooper, J.B. | Deposit date: | 2001-07-09 | Release date: | 2001-07-12 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The X-Ray Structure of Yeast 5-Aminolaevulinic Acid Dehydratase Complexed with Substrate and Three Inhibitors J.Mol.Biol., 312, 2001
|
|