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3CF1
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BU of 3cf1 by Molmil
Structure of P97/vcp in complex with ADP/ADP.alfx
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ALUMINUM FLUORIDE, Transitional endoplasmic reticulum ATPase
Authors:Davies, J.M, Delabarre, B, Brunger, A.T, Weis, W.I.
Deposit date:2008-03-01
Release date:2008-04-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (4.4 Å)
Cite:Improved structures of full-length p97, an AAA ATPase: implications for mechanisms of nucleotide-dependent conformational change.
Structure, 16, 2008
1JPP
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BU of 1jpp by Molmil
The Structure of a beta-Catenin Binding Repeat from Adenomatous Polyposis Coli (APC) in Complex with beta-Catenin
Descriptor: ADENOMATOUS POLYPOSIS COLI PROTEIN, BETA-CATENIN, GLYCEROL
Authors:Spink, K.E, Fridman, S.G, Weis, W.I.
Deposit date:2001-08-02
Release date:2002-01-16
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Molecular mechanisms of beta-catenin recognition by adenomatous polyposis coli revealed by the structure of an APC-beta-catenin complex.
EMBO J., 20, 2001
1AFD
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BU of 1afd by Molmil
STRUCTURAL BASIS OF GALACTOSE RECOGNITION IN C-TYPE ANIMAL LECTINS
Descriptor: CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN-A
Authors:Kolatkar, A.R, Weis, W.I.
Deposit date:1995-11-03
Release date:1996-04-03
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of galactose recognition by C-type animal lectins.
J.Biol.Chem., 271, 1996
3CF0
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BU of 3cf0 by Molmil
Structure of D2 subdomain of P97/VCP in complex with ADP
Descriptor: ADENOSINE-5'-DIPHOSPHATE, Transitional endoplasmic reticulum ATPase
Authors:Davies, J.M, Brunger, A.T, Weis, W.I.
Deposit date:2008-03-01
Release date:2008-04-22
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (3 Å)
Cite:Improved Structures of Full-Length p97, an AAA ATPase: Implications for Mechanisms of Nucleotide-Dependent Conformational Change.
Structure, 16, 2008
1AFB
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BU of 1afb by Molmil
STRUCTURAL BASIS OF GALACTOSE RECOGNITION IN C-TYPE ANIMAL LECTINS
Descriptor: 2-acetamido-2-deoxy-beta-D-galactopyranose, CALCIUM ION, CHLORIDE ION, ...
Authors:Kolatkar, A.R, Weis, W.I.
Deposit date:1995-11-03
Release date:1996-04-03
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural basis of galactose recognition by C-type animal lectins.
J.Biol.Chem., 271, 1996
1AFA
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BU of 1afa by Molmil
STRUCTURAL BASIS OF GALACTOSE RECOGNITION IN C-TYPE ANIMAL LECTINS
Descriptor: CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN-A, ...
Authors:Kolatkar, A.R, Weis, W.I.
Deposit date:1995-11-03
Release date:1996-04-03
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis of galactose recognition by C-type animal lectins.
J.Biol.Chem., 271, 1996
1BCJ
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BU of 1bcj by Molmil
MANNOSE-BINDING PROTEIN-A MUTANT (QPDWGHV) COMPLEXED WITH N-ACETYL-D-GALACTOSAMINE
Descriptor: 2-acetamido-2-deoxy-beta-D-galactopyranose, CALCIUM ION, CHLORIDE ION, ...
Authors:Kolatkar, A.R, Weis, W.I.
Deposit date:1998-04-30
Release date:1998-06-17
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanism of N-acetylgalactosamine binding to a C-type animal lectin carbohydrate-recognition domain.
J.Biol.Chem., 273, 1998
1BCH
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BU of 1bch by Molmil
MANNOSE-BINDING PROTEIN-A MUTANT (QPDWGH) COMPLEXED WITH N-ACETYL-D-GALACTOSAMINE
Descriptor: 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-galactopyranose, CALCIUM ION, ...
Authors:Kolatkar, A.R, Weis, W.I.
Deposit date:1998-04-30
Release date:1998-06-17
Last modified:2023-08-02
Method:X-RAY DIFFRACTION (2 Å)
Cite:Mechanism of N-acetylgalactosamine binding to a C-type animal lectin carbohydrate-recognition domain.
J.Biol.Chem., 273, 1998
1EGG
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BU of 1egg by Molmil
STRUCTURE OF A C-TYPE CARBOHYDRATE-RECOGNITION DOMAIN (CRD-4) FROM THE MACROPHAGE MANNOSE RECEPTOR
Descriptor: CALCIUM ION, MACROPHAGE MANNOSE RECEPTOR
Authors:Feinberg, H, Park-Snyder, S, Kolatkar, A.R, Heise, C.T, Taylor, M.E, Weis, W.I.
Deposit date:2000-02-15
Release date:2000-08-30
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structure of a C-type carbohydrate recognition domain from the macrophage mannose receptor.
J.Biol.Chem., 275, 2000
1FIH
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BU of 1fih by Molmil
N-ACETYLGALACTOSAMINE BINDING MUTANT OF MANNOSE-BINDING PROTEIN A (QPDWG-HDRPY), COMPLEX WITH N-ACETYLGALACTOSAMINE
Descriptor: 2-acetamido-2-deoxy-beta-D-galactopyranose, CALCIUM ION, CHLORIDE ION, ...
Authors:Feinberg, H, Torgerson, D, Drickamer, K, Weis, W.I.
Deposit date:2000-08-03
Release date:2000-08-23
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Mechanism of pH-dependent N-acetylgalactosamine binding by a functional mimic of the hepatocyte asialoglycoprotein receptor.
J.Biol.Chem., 275, 2000
1FIF
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BU of 1fif by Molmil
N-ACETYLGALACTOSAMINE-SELECTIVE MUTANT OF MANNOSE-BINDING PROTEIN-A (QPDWG-HDRPY)
Descriptor: CALCIUM ION, CHLORIDE ION, MANNOSE-BINDING PROTEIN-A
Authors:Feinberg, H, Torgersen, D, Drickamer, K, Weis, W.I.
Deposit date:2000-08-03
Release date:2000-08-23
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Mechanism of pH-dependent N-acetylgalactosamine binding by a functional mimic of the hepatocyte asialoglycoprotein receptor.
J.Biol.Chem., 275, 2000
1HVV
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BU of 1hvv by Molmil
SELF-ASSOCIATION OF THE H3 REGION OF SYNTAXIN 1A: IMPLICATIONS FOR SNARE COMPLEX ASSEMBLY
Descriptor: D(-)-TARTARIC ACID, SYNTAXIN 1A
Authors:Misura, K.M.S, Scheller, R.H, Weis, W.I.
Deposit date:2001-01-08
Release date:2001-01-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Self-association of the H3 region of syntaxin 1A. Implications for intermediates in SNARE complex assembly.
J.Biol.Chem., 276, 2001
1IFQ
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BU of 1ifq by Molmil
Sec22b N-terminal domain
Descriptor: GLYCEROL, vesicle trafficking protein Sec22b
Authors:Gonzalez Jr, L.C, Weis, W.I, Scheller, R.H.
Deposit date:2001-04-13
Release date:2001-05-02
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:A novel snare N-terminal domain revealed by the crystal structure of Sec22b.
J.Biol.Chem., 276, 2001
1QDN
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BU of 1qdn by Molmil
AMINO TERMINAL DOMAIN OF THE N-ETHYLMALEIMIDE SENSITIVE FUSION PROTEIN (NSF)
Descriptor: BETA-MERCAPTOETHANOL, PROTEIN (N-ETHYLMALEIMIDE SENSITIVE FUSION PROTEIN (NSF)), SULFATE ION
Authors:May, A.P, Misura, K.M.S, Whiteheart, S.W, Weis, W.I.
Deposit date:1999-05-21
Release date:1999-06-21
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Crystal structure of the amino-terminal domain of N-ethylmaleimide-sensitive fusion protein.
Nat.Cell Biol., 1, 1999
1SL5
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BU of 1sl5 by Molmil
Crystal Structure of DC-SIGN carbohydrate recognition domain complexed with LNFP III (Dextra L504).
Descriptor: CALCIUM ION, MAGNESIUM ION, alpha-L-fucopyranose-(1-3)-[beta-D-galactopyranose-(1-4)]2-acetamido-2-deoxy-beta-D-glucopyranose-(1-3)-beta-D-galactopyranose, ...
Authors:Guo, Y, Feinberg, H, Conroy, E, Mitchell, D.A, Alvarez, R, Blixt, O, Taylor, M.E, Weis, W.I, Drickamer, K.
Deposit date:2004-03-05
Release date:2004-06-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Structural basis for distinct ligand-binding and targeting properties of the receptors DC-SIGN and DC-SIGNR
Nat.Struct.Mol.Biol., 11, 2004
1SL4
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BU of 1sl4 by Molmil
Crystal Structure of DC-SIGN carbohydrate recognition domain complexed with Man4
Descriptor: CALCIUM ION, alpha-D-mannopyranose-(1-3)-[alpha-D-mannopyranose-(1-6)]alpha-D-mannopyranose-(1-6)-alpha-D-mannopyranose, mDC-SIGN1B type I isoform
Authors:Guo, Y, Feinberg, H, Conroy, E, Mitchell, D.A, Alvarez, R, Blixt, O, Taylor, M.E, Weis, W.I, Drickamer, K.
Deposit date:2004-03-05
Release date:2004-06-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (1.55 Å)
Cite:Structural basis for distinct ligand-binding and targeting properties of the receptors DC-SIGN and DC-SIGNR
Nat.Struct.Mol.Biol., 11, 2004
1SL6
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BU of 1sl6 by Molmil
Crystal Structure of a fragment of DC-SIGNR (containg the carbohydrate recognition domain and two repeats of the neck) complexed with Lewis-x.
Descriptor: C-type lectin DC-SIGNR, CALCIUM ION, alpha-L-fucopyranose-(1-3)-[beta-D-galactopyranose-(1-4)]2-acetamido-2-deoxy-alpha-D-glucopyranose
Authors:Guo, Y, Feinberg, H, Conroy, E, Mitchell, D.A, Alvarez, R, Blixt, O, Taylor, M.E, Weis, W.I, Drickamer, K.
Deposit date:2004-03-05
Release date:2004-06-15
Last modified:2020-07-29
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Structural basis for distinct ligand-binding and targeting properties of the receptors DC-SIGN and DC-SIGNR
Nat.Struct.Mol.Biol., 11, 2004
1T08
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BU of 1t08 by Molmil
Crystal structure of beta-catenin/ICAT helical domain/unphosphorylated APC R3
Descriptor: Adenomatous polyposis coli protein, Beta-catenin, Beta-catenin-interacting protein 1
Authors:Ha, N.-C, Tonozuka, T, Stamos, J.L, Weis, W.I.
Deposit date:2004-04-07
Release date:2004-10-12
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation
Mol.Cell, 15, 2004
5XA5
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BU of 5xa5 by Molmil
Crystal structure of HMP-1-HMP-2 complex
Descriptor: Alpha-catenin-like protein hmp-1, Beta-catenin-like protein hmp-2
Authors:Shao, X, Kang, H, Weis, W.I, Hardin, J, Choi, H.J.
Deposit date:2017-03-11
Release date:2017-08-30
Last modified:2024-03-27
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:Cell-cell adhesion in metazoans relies on evolutionarily conserved features of the alpha-catenin· beta-catenin-binding interface.
J.Biol.Chem., 292, 2017
5X7D
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BU of 5x7d by Molmil
Structure of beta2 adrenoceptor bound to carazolol and an intracellular allosteric antagonist
Descriptor: (2S)-1-(9H-Carbazol-4-yloxy)-3-(isopropylamino)propan-2-ol, 1,4-BUTANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ...
Authors:Liu, X, Ahn, S, Kahsai, A.W, Meng, K.-C, Latorraca, N.R, Pani, B, Venkatakrishnan, A.J, Masoudi, A, Weis, W.I, Dror, R.O, Chen, X, Lefkowitz, R.J, Kobilka, B.K.
Deposit date:2017-02-25
Release date:2017-08-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.703 Å)
Cite:Mechanism of intracellular allosteric beta 2AR antagonist revealed by X-ray crystal structure.
Nature, 548, 2017
2M4N
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BU of 2m4n by Molmil
Solution structure of the putative Ras interaction domain of AFD-1, isoform a from Caenorhabditis elegans
Descriptor: Protein AFD-1, isoform a
Authors:Harris, R, Hillerich, B, Ahmed, M, Bonanno, J.B, Chamala, S, Evans, B, Lafleur, J, Hammonds, J, Washington, E, Stead, M, Love, J, Attonito, J, Seidel, R.D, Liddington, R.C, Weis, W.I, Nelson, W.J, Girvin, M.E, Almo, S.C, New York Structural Genomics Research Consortium (NYSGRC), Assembly, Dynamics and Evolution of Cell-Cell and Cell-Matrix Adhesions (CELLMAT)
Deposit date:2013-02-07
Release date:2013-03-20
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structure of the putative Ras interaction domain of AFD-1, isoform a from Caenorhabditis elegans
To be Published
2OAJ
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BU of 2oaj by Molmil
Crystal structure of Sro7 from S. cerevisiae
Descriptor: Protein SNI1, SODIUM ION, ZINC ION
Authors:Hattendorf, D.A, Weis, W.I.
Deposit date:2006-12-15
Release date:2007-04-03
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of the yeast polarity protein Sro7 reveals a SNARE regulatory mechanism.
Nature, 446, 2007
4YUP
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BU of 4yup by Molmil
Multiconformer fixed-target X-ray free electron (XFEL) model of CypA at 273 K
Descriptor: Peptidyl-prolyl cis-trans isomerase A
Authors:Keedy, D.A, Kenner, L.R, Warkentin, M, Woldeyes, R.A, Thompson, M.C, Brewster, A.S, Van Benschoten, A.H, Baxter, E.L, Hopkins, J.B, Uervirojnangkoorn, M, McPhillips, S.E, Song, J, Mori, R.A, Holton, J.M, Weis, W.I, Brunger, A.T, Soltis, M, Lemke, H, Gonzalez, A, Sauter, N.K, Cohen, A.E, van den Bedem, H, Thorne, R.E, Fraser, J.S.
Deposit date:2015-03-18
Release date:2015-10-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography.
Elife, 4, 2015
4YUG
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BU of 4yug by Molmil
Multiconformer synchrotron model of CypA at 100 K
Descriptor: Peptidyl-prolyl cis-trans isomerase A
Authors:Keedy, D.A, Kenner, L.R, Warkentin, M, Woldeyes, R.A, Thompson, M.C, Brewster, A.S, Van Benschoten, A.H, Baxter, E.L, Hopkins, J.B, Uervirojnangkoorn, M, McPhillips, S.E, Song, J, Mori, R.A, Holton, J.M, Weis, W.I, Brunger, A.T, Soltis, M, Lemke, H, Gonzalez, A, Sauter, N.K, Cohen, A.E, van den Bedem, H, Thorne, R.E, Fraser, J.S.
Deposit date:2015-03-18
Release date:2015-10-14
Last modified:2024-02-28
Method:X-RAY DIFFRACTION (1.48 Å)
Cite:Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography.
Elife, 4, 2015
4YUL
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BU of 4yul by Molmil
Multiconformer synchrotron model of CypA at 280 K
Descriptor: Peptidyl-prolyl cis-trans isomerase A
Authors:Keedy, D.A, Kenner, L.R, Warkentin, M, Woldeyes, R.A, Thompson, M.C, Brewster, A.S, Van Benschoten, A.H, Baxter, E.L, Hopkins, J.B, Uervirojnangkoorn, M, McPhillips, S.E, Song, J, Mori, R.A, Holton, J.M, Weis, W.I, Brunger, A.T, Soltis, M, Lemke, H, Gonzalez, A, Sauter, N.K, Cohen, A.E, van den Bedem, H, Thorne, R.E, Fraser, J.S.
Deposit date:2015-03-18
Release date:2015-10-14
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.42 Å)
Cite:Mapping the conformational landscape of a dynamic enzyme by multitemperature and XFEL crystallography.
Elife, 4, 2015

219869

數據於2024-05-15公開中

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