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1BMK
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THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB218655
分子名称: 4-(FLUOROPHENYL)-1-CYCLOPROPYLMETHYL-5-(2-AMINO-4-PYRIMIDINYL)IMIDAZOLE, PROTEIN (MAP KINASE P38)
著者Wang, Z, Canagarajah, B, Boehm, J.C, Kassis, S, Cobb, M.H, Young, P.R, Abdel-Meguid, S, Adams, J.L, Goldsmith, E.J.
登録日1998-07-23
公開日1999-07-23
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural basis of inhibitor selectivity in MAP kinases.
Structure, 6, 1998
1BL6
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THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB216995
分子名称: 4-(4-FLUOROPHENYL)-1-CYCLOROPROPYLMETHYL-5-(4-PYRIDYL)-IMIDAZOLE, PROTEIN (MAP KINASE P38)
著者Wang, Z, Canagarajah, B.J, Boehm, J.C, Kassis, S, Cobb, M.H, Young, P.R, Abdel-Meguid, S, Adams, J.L, Goldsmith, E.J.
登録日1998-07-11
公開日1999-07-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of inhibitor selectivity in MAP kinases.
Structure, 6, 1998
1BL7
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THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB220025
分子名称: 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE, PROTEIN (MAP KINASE P38)
著者Wang, Z, Canagarajah, B.J, Boehm, J.C, Kassis, S, Cobb, M.H, Young, P.R, Abdel-Meguid, S, Adams, J.L, Goldsmith, E.J.
登録日1998-07-23
公開日1999-07-26
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of inhibitor selectivity in MAP kinases.
Structure, 6, 1998
1A9U
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BU of 1a9u by Molmil
THE COMPLEX STRUCTURE OF THE MAP KINASE P38/SB203580
分子名称: 4-[5-(4-FLUORO-PHENYL)-2-(4-METHANESULFINYL-PHENYL)-3H-IMIDAZOL-4-YL]-PYRIDINE, MAP KINASE P38
著者Wang, Z, Canagarajah, B, Boehm, J.C, Kassis, S, Cobb, M.H, Young, P.R, Abdel-Meguid, S, Adams, J.L, Goldsmith, E.J.
登録日1998-04-10
公開日1999-04-20
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of inhibitor selectivity in MAP kinases.
Structure, 6, 1998
1A4M
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BU of 1a4m by Molmil
ADA STRUCTURE COMPLEXED WITH PURINE RIBOSIDE AT PH 7.0
分子名称: 6-HYDROXY-1,6-DIHYDRO PURINE NUCLEOSIDE, ADENOSINE DEAMINASE, ZINC ION
著者Wang, Z, Quiocho, F.A.
登録日1998-01-31
公開日1998-10-14
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Complexes of adenosine deaminase with two potent inhibitors: X-ray structures in four independent molecules at pH of maximum activity.
Biochemistry, 37, 1998
1A4L
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ADA STRUCTURE COMPLEXED WITH DEOXYCOFORMYCIN AT PH 7.0
分子名称: 2'-DEOXYCOFORMYCIN, ADENOSINE DEAMINASE, ZINC ION
著者Wang, Z, Quiocho, F.A.
登録日1998-01-31
公開日1998-10-14
最終更新日2023-08-02
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Complexes of adenosine deaminase with two potent inhibitors: X-ray structures in four independent molecules at pH of maximum activity.
Biochemistry, 37, 1998
1IXG
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BU of 1ixg by Molmil
PHOSPHATE-BINDING PROTEIN MUTANT WITH THR 141 REPLACED BY ASP (T141D), COMPLEXED WITH PHOSPATE
分子名称: PHOSPHATE ION, PHOSPHATE-BINDING PROTEIN
著者Wang, Z, Luecke, H, Quiocho, F.A.
登録日1996-08-01
公開日1998-02-04
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献A low energy short hydrogen bond in very high resolution structures of protein receptor--phosphate complexes.
Nat.Struct.Biol., 4, 1997
1IXI
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PHOSPHATE-BINDING PROTEIN MUTANT WITH ASP 56 REPLACED BY ASN COMPLEX WITH MONOBASIC PHOSPHATE ION
分子名称: DIHYDROGENPHOSPHATE ION, PHOSPHATE-BINDING PROTEIN
著者Wang, Z, Quiocho, F.A.
登録日1996-10-17
公開日1997-10-22
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献A low energy short hydrogen bond in very high resolution structures of protein receptor--phosphate complexes.
Nat.Struct.Biol., 4, 1997
1IXH
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BU of 1ixh by Molmil
PHOSPHATE-BINDING PROTEIN (PBP) COMPLEXED WITH PHOSPHATE
分子名称: PHOSPHATE ION, PHOSPHATE-BINDING PROTEIN
著者Wang, Z, Luecke, H, Quiocho, F.A.
登録日1996-08-01
公開日1998-02-04
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (0.98 Å)
主引用文献A low energy short hydrogen bond in very high resolution structures of protein receptor--phosphate complexes.
Nat.Struct.Biol., 4, 1997
4QC2
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BU of 4qc2 by Molmil
Crystal structure of lipopolysaccharide transport protein LptB in complex with ATP and Magnesium ions
分子名称: ABC transporter related protein, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION
著者Wang, Z, Xiang, Q, Zhu, X, Dong, H, He, C, Wang, H, Zhang, Y, Wang, W, Dong, C.
登録日2014-05-09
公開日2014-10-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.22 Å)
主引用文献Structural and functional studies of conserved nucleotide-binding protein LptB in lipopolysaccharide transport.
Biochem.Biophys.Res.Commun., 452, 2014
4RF9
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BU of 4rf9 by Molmil
Crystal structure of double-domain arginine kinase from Anthopleura japonicas in complex with L-arginine and ATPgS
分子名称: ACETATE ION, ARGININE, Arginine kinase, ...
著者Wang, Z, Qiao, Z, Ye, S, Zhang, R.
登録日2014-09-25
公開日2015-04-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structure of a double-domain phosphagen kinase reveals an asymmetric arrangement of the tandem domains.
Acta Crystallogr.,Sect.D, 71, 2015
4RF6
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Crystal structure of double-domain arginine kinase from Anthopleura japonicas
分子名称: Arginine kinase
著者Wang, Z, Qiao, Z, Ye, S, Zhang, R.
登録日2014-09-25
公開日2015-04-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure of a double-domain phosphagen kinase reveals an asymmetric arrangement of the tandem domains.
Acta Crystallogr.,Sect.D, 71, 2015
4RF8
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Crystal structure of double-domain arginine kinase from Anthopleura japonicas in complex with ADP
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, ADENOSINE-5'-DIPHOSPHATE, Arginine kinase, ...
著者Wang, Z, Qiao, Z, Ye, S, Zhang, R.
登録日2014-09-25
公開日2015-04-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Structure of a double-domain phosphagen kinase reveals an asymmetric arrangement of the tandem domains.
Acta Crystallogr.,Sect.D, 71, 2015
4RF7
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BU of 4rf7 by Molmil
Crystal structure of double-domain arginine kinase from Anthopleura japonicas in complex with substrate L-arginine
分子名称: ACETATE ION, ARGININE, Arginine kinase
著者Wang, Z, Qiao, Z, Ye, S, Zhang, R.
登録日2014-09-25
公開日2015-04-08
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of a double-domain phosphagen kinase reveals an asymmetric arrangement of the tandem domains.
Acta Crystallogr.,Sect.D, 71, 2015
1PBP
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BU of 1pbp by Molmil
FINE TUNING OF THE SPECIFICITY OF THE PERIPLASMIC PHOSPHATE TRANSPORT RECEPTOR: SITE-DIRECTED MUTAGENESIS, LIGAND BINDING, AND CRYSTALLOGRAPHIC STUDIES
分子名称: PHOSPHATE ION, PHOSPHATE-BINDING PROTEIN
著者Wang, Z, Choudhary, A, Ledvina, P.S, Quiocho, F.A.
登録日1994-07-20
公開日1994-10-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Fine tuning the specificity of the periplasmic phosphate transport receptor. Site-directed mutagenesis, ligand binding, and crystallographic studies.
J.Biol.Chem., 269, 1994
5NG5
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BU of 5ng5 by Molmil
multi-drug efflux; membrane transport; RND superfamily; Drug resistance
分子名称: 6-[2-(3,4-dimethoxyphenyl)ethylsulfanyl]-8-[4-(2-methoxyethyl)piperazin-1-yl]-3,3-dimethyl-1,4-dihydropyrano[3,4-c]pyridine-5-carbonitrile, Multidrug efflux pump accessory protein AcrZ, Multidrug efflux pump subunit AcrA, ...
著者Wang, Z, Fan, G, Hryc, C.F, Blaza, J.N, Serysheva, I.I, Schmid, M.F, Chiu, W, Luisi, B.F, Du, D.
登録日2017-03-16
公開日2017-04-19
最終更新日2017-08-02
実験手法ELECTRON MICROSCOPY (6.5 Å)
主引用文献An allosteric transport mechanism for the AcrAB-TolC Multidrug Efflux Pump.
Elife, 6, 2017
7NEP
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BU of 7nep by Molmil
Homology model of the in situ actomyosin complex from the A-band of mouse psoas muscle sarcomere in the rigor state
分子名称: Actin, alpha skeletal muscle, Myosin light chain 1/3, ...
著者Wang, Z, Grange, M, Wagner, T, Kho, A.L, Gautel, M, Raunser, S.
登録日2021-02-04
公開日2021-04-07
最終更新日2021-04-28
実験手法ELECTRON MICROSCOPY (10.2 Å)
主引用文献The molecular basis for sarcomere organization in vertebrate skeletal muscle.
Cell, 184, 2021
3ERK
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BU of 3erk by Molmil
THE COMPLEX STRUCTURE OF THE MAP KINASE ERK2/SB220025
分子名称: 4-(4-FLUOROPHENYL)-1-(4-PIPERIDINYL)-5-(2-AMINO-4-PYRIMIDINYL)-IMIDAZOLE, EXTRACELLULAR REGULATED KINASE 2
著者Wang, Z, Canagarajah, B, Boehm, J.C, Cobb, M.H, Young, P.R, Abdel-Meguid, S, Adams, J.L, Goldsmith, E.J.
登録日1998-07-09
公開日1999-07-22
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of inhibitor selectivity in MAP kinases.
Structure, 6, 1998
1ZW8
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Solution structure of a ZAP1 zinc-responsive domain provides insights into metalloregulatory transcriptional repression in Saccharomyces cerevisiae
分子名称: ZINC ION, Zinc-responsive transcriptional regulator ZAP1
著者Wang, Z, Feng, L.S, Venkataraman, K, Matskevich, V.A, Parasuram, P, Laity, J.H.
登録日2005-06-03
公開日2006-01-10
最終更新日2021-10-20
実験手法SOLUTION NMR
主引用文献Solution structure of a Zap1 zinc-responsive domain provides insights into metalloregulatory transcriptional repression in Saccharomyces cerevisiae.
J.Mol.Biol., 357, 2006
6P6J
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Structure of YbtPQ importer with substrate Ybt-Fe bound
分子名称: ABC transporter protein, FE (III) ION, inner membrane ABC-transporter, ...
著者Wang, Z, Hu, W, Zheng, H.
登録日2019-06-04
公開日2020-03-04
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Pathogenic siderophore ABC importer YbtPQ adopts a surprising fold of exporter.
Sci Adv, 6, 2020
6P6I
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Structure of YbtPQ importer
分子名称: ABC transporter protein, inner membrane ABC-transporter
著者Wang, Z, Hu, W, Zheng, H.
登録日2019-06-04
公開日2020-03-04
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.67 Å)
主引用文献Pathogenic siderophore ABC importer YbtPQ adopts a surprising fold of exporter.
Sci Adv, 6, 2020
3LPY
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BU of 3lpy by Molmil
Crystal structure of the RRM domain of CyP33
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Peptidyl-prolyl cis-trans isomerase E, SULFATE ION
著者Wang, Z, Patel, D.J.
登録日2010-02-07
公開日2010-07-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression.
Cell(Cambridge,Mass.), 141, 2010
3LQH
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Crystal structure of MLL1 PHD3-Bromo in the free form
分子名称: Histone-lysine N-methyltransferase MLL, ZINC ION
著者Wang, Z, Patel, D.J.
登録日2010-02-09
公開日2010-07-07
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.72 Å)
主引用文献Pro isomerization in MLL1 PHD3-bromo cassette connects H3K4me readout to CyP33 and HDAC-mediated repression.
Cell(Cambridge,Mass.), 141, 2010
7Q48
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Solution structure of an intramolecular RNA G-quadruplex formed by the 6A8U17U mutant from a 22mer guanine-rich sequence within the 5'UTR of BCL-2 proto onco-gene
分子名称: RNA (5'-R(*GP*GP*GP*CP*CP*AP*UP*UP*GP*GP*GP*UP*GP*GP*GP*AP*UP*CP*UP*GP*GP*G)-3')
著者Wang, Z, Jurt, S, Dominguez-Martin, A, Johannsen, S, Sigel, R.K.O.
登録日2021-10-29
公開日2022-11-16
実験手法SOLUTION NMR
主引用文献Solution structure of an intramolecular RNA G-quadruplex formed by the 6A8U17U mutant from a 22mer guanine-rich sequence within the 5'UTR of BCL-2 proto onco-gene
To Be Published
7Q6L
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Solution structure of an intramolecular RNA G-quadruplex formed by the 6A8A17U mutant from a 22mer guanine-rich sequence within the 5'UTR of BCL-2 proto-oncogene
分子名称: RNA (5'-R(*GP*GP*GP*CP*CP*AP*UP*AP*GP*GP*GP*UP*GP*GP*GP*AP*UP*CP*UP*GP*GP*G)-3')
著者Wang, Z, Jurt, S, Dominguez-Martin, A, Johannsen, S, Sigel, R.K.O.
登録日2021-11-08
公開日2022-11-16
最終更新日2024-01-31
実験手法SOLUTION NMR
主引用文献Solution structure of an intramolecular RNA G-quadruplex formed by the 6A8A17U mutant from a 22mer guanine-rich sequence within the 5'UTR of BCL-2 proto-oncogene
To Be Published

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