1A4L

ADA STRUCTURE COMPLEXED WITH DEOXYCOFORMYCIN AT PH 7.0

Summary for 1A4L

DescriptorADENOSINE DEAMINASE, ZINC ION, 2'-DEOXYCOFORMYCIN, ... (4 entities in total)
Functional Keywordshydrolase, adenosine deaminase, pentostatin, deoxycoformycin
Biological sourceMus musculus (house mouse)
Cellular locationCell membrane; Peripheral membrane protein; Extracellular side (By similarity) P03958
Total number of polymer chains4
Total molecular weight160195.46
Authors
Wang, Z.,Quiocho, F.A. (deposition date: 1998-01-31, release date: 1998-10-14, Last modification date: 2011-07-13)
Primary citation
Wang, Z.,Quiocho, F.A.
Complexes of adenosine deaminase with two potent inhibitors: X-ray structures in four independent molecules at pH of maximum activity.
Biochemistry, 37:8314-8324, 1998
PubMed: 9622483 (PDB entries with the same primary citation)
DOI: 10.1021/bi980324o
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.6 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers120.9%7.6%0.1%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution

More Asymmetric unit images

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