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5T3Y
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BU of 5t3y by Molmil
Solution structure of response regulator protein from Burkholderia multivorans
Descriptor: Two-component system response regulator
Authors:Yang, F, Lim, Y.-B, Barnwal, R, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2016-08-26
Release date:2016-09-14
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution structure of response regulator protein from Burkholderia multivorans
To Be Published
5VO7
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BU of 5vo7 by Molmil
NMR Assignment and Structure of Thioredoxin (Rv1471 ortholog) from Mycobacterium smegmatis ATCC 700084 / mc(2)155
Descriptor: Thioredoxin
Authors:Barnwal, R.P, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2017-05-02
Release date:2017-06-07
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Assignment and Structure of Thioredoxin (Rv1471 ortholog) type protein from Mycobacterium smegmatis ATCC 700084 / mc(2)155
To Be Published
5UZZ
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BU of 5uzz by Molmil
Structure of wild type pre-miR21 apical loop
Descriptor: 14-mer Peptide, pre-miR21
Authors:Shortridge, M.D, Varani, G.
Deposit date:2017-02-27
Release date:2017-06-14
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A Macrocyclic Peptide Ligand Binds the Oncogenic MicroRNA-21 Precursor and Suppresses Dicer Processing.
ACS Chem. Biol., 12, 2017
5UZT
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BU of 5uzt by Molmil
Structure of wild type pre-miR21 apical loop
Descriptor: pre-miR-21
Authors:Shortridge, M.D, Varani, G.
Deposit date:2017-02-27
Release date:2017-05-10
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:A Macrocyclic Peptide Ligand Binds the Oncogenic MicroRNA-21 Precursor and Suppresses Dicer Processing.
ACS Chem. Biol., 12, 2017
6D2U
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BU of 6d2u by Molmil
Solution structure of a ultra-high affinity macrocycle bound to HIV-1 TAR RNA
Descriptor: DAB-VAL-ARG-THR-ARG-LYS-GLY-ARG-ARG-ILE-NOR-ILE-DPR-PRO, RNA (29-MER)
Authors:Shortridge, M.D, Varani, G.
Deposit date:2018-04-13
Release date:2018-12-12
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:An ultra-high affinity ligand of HIV-1 TAR reveals the RNA structure recognized by P-TEFb.
Nucleic Acids Res., 47, 2019
1M5L
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BU of 1m5l by Molmil
Structure of wild-type and mutant internal loops from the SL-1 domain of the HIV-1 packaging signal
Descriptor: modified HIV-1 packaging signal stem-loop 1 RNA
Authors:Gallego, J, Greatorex, J, Varani, G, Lever, A.
Deposit date:2002-07-09
Release date:2002-09-18
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Structure and stability of wild-type and mutant RNA internal loops from the SL-1 domain of the HIV-1 packaging signal
J.Mol.Biol., 322, 2002
6C2V
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BU of 6c2v by Molmil
Solution structure of a phosphate-loop protein
Descriptor: phosphate-loop protein
Authors:Yang, F, Yang, W, Lin, Y.R, Romero Romero, M.L, Tawfik, D, Baker, D, Varani, G.
Deposit date:2018-01-09
Release date:2018-11-21
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Simple yet functional phosphate-loop proteins.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1OQ0
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BU of 1oq0 by Molmil
P6.1 stem loop from the activation domain of hTR
Descriptor: P6.1 RNA hairpin from hTR
Authors:Leeper, T, Leulliot, N, Varani, G.
Deposit date:2003-03-06
Release date:2003-05-13
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The solution structure of an essential stem-loop of human telomerase RNA
NUCLEIC ACIDS RES., 31, 2003
6DZ9
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BU of 6dz9 by Molmil
Solution structure of Rbfox2 RRM mimetic peptide CPfox2
Descriptor: CPfox2
Authors:Sun, Y.-T, Shortridge, M.D, Varani, G.
Deposit date:2018-07-03
Release date:2019-05-15
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A Small Cyclic beta-Hairpin Peptide Mimics the Rbfox2 RNA Recognition Motif and Binds to the Precursor miRNA 20b.
Chembiochem, 20, 2019
6DZB
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BU of 6dzb by Molmil
Solution structure of Rbfox2 RRM mimetic peptide CPfox5
Descriptor: CPfox5
Authors:Sun, Y.-T, Varani, G.
Deposit date:2018-07-03
Release date:2019-05-15
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:A Small Cyclic beta-Hairpin Peptide Mimics the Rbfox2 RNA Recognition Motif and Binds to the Precursor miRNA 20b.
Chembiochem, 20, 2019
1EKZ
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BU of 1ekz by Molmil
NMR STRUCTURE OF THE COMPLEX BETWEEN THE THIRD DSRBD FROM DROSOPHILA STAUFEN AND A RNA HAIRPIN
Descriptor: MATERNAL EFFECT PROTEIN (STAUFEN), STAUFEN DOUBLE-STRANDED RNA BINDING DOMAIN
Authors:Ramos, A, Grunert, S, Bycroft, M, St Johnston, D, Varani, G.
Deposit date:2000-03-11
Release date:2000-08-21
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:RNA recognition by a Staufen double-stranded RNA-binding domain.
EMBO J., 19, 2000
6C2U
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BU of 6c2u by Molmil
Solution structure of a phosphate-loop protein
Descriptor: phosphate-loop protein
Authors:Yang, F, Yang, W, Lin, Y.R, Romero Romero, M.L, Tawfik, D, Baker, D, Varani, G.
Deposit date:2018-01-09
Release date:2018-11-21
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Simple yet functional phosphate-loop proteins.
Proc. Natl. Acad. Sci. U.S.A., 115, 2018
1FHT
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BU of 1fht by Molmil
RNA-BINDING DOMAIN OF THE U1A SPLICEOSOMAL PROTEIN U1A117, NMR, 43 STRUCTURES
Descriptor: U1 SMALL NUCLEAR RIBONUCLEOPROTEIN A
Authors:Allain, F.H.-T, Gubser, C.C, Howe, P.W.A, Nagai, K, Neuhaus, D, Varani, G.
Deposit date:1996-02-21
Release date:1996-07-11
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the N-terminal RNP domain of U1A protein: the role of C-terminal residues in structure stability and RNA binding.
J.Mol.Biol., 257, 1996
1P1T
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BU of 1p1t by Molmil
NMR Structure of the N-terminal RRM domain of Cleavage stimulation factor 64 KDa subunit
Descriptor: Cleavage stimulation factor, 64 kDa subunit
Authors:Perez-Canadillas, J.M, Varani, G.
Deposit date:2003-04-14
Release date:2003-08-12
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Recognition of GU-rich polyadenylation regulatory elements by human CstF-64 protein
Embo J., 22, 2003
1M82
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BU of 1m82 by Molmil
SOLUTION STRUCTURE OF THE COMPLEMENTARY RNA PROMOTER OF INFLUENZA A VIRUS
Descriptor: RNA (25-MER): THE COMPLEMENTARY RNA PROMOTER OF INFLUENZA A VIRUS
Authors:Park, C.-J, Bae, S.-H, Lee, M.-K, Varani, G, Choi, B.-S.
Deposit date:2002-07-24
Release date:2003-06-03
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Solution structure of the influenza A virus cRNA promoter: implications for differential recognition of viral promoter structures by RNA-dependent RNA polymerase
NUCLEIC ACIDS RES., 31, 2003
1T4N
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BU of 1t4n by Molmil
Solution structure of Rnt1p dsRBD
Descriptor: Ribonuclease III
Authors:Leulliot, N, Quevillon-Cheruel, S, Graille, M, van Tilbeurgh, H, Leeper, T.C, Godin, K.S, Edwards, T.E, Sigurdsson, S.T, Rozenkrants, N, Nagel, R.J, Ares, M, Varani, G.
Deposit date:2004-04-30
Release date:2004-07-13
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:A new alpha-helical extension promotes RNA binding by the dsRBD of Rnt1p RNAse III
Embo J., 23, 2004
1T4O
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BU of 1t4o by Molmil
Crystal structure of rnt1p dsRBD
Descriptor: Ribonuclease III
Authors:Leulliot, N, Quevillon-Cheruel, S, Graille, M, van Tilbeurgh, H, Leeper, T.C, Godin, K.S, Edwards, T.E, Sigurdsson, S.T, Rozenkrants, N, Nagel, R.J, Ares Jr, M, Varani, G.
Deposit date:2004-04-30
Release date:2004-06-22
Last modified:2023-08-23
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:A new alpha-helical extension promotes RNA binding by the dsRBD of Rnt1p RNAse III
Embo J., 23, 2004
2J8P
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BU of 2j8p by Molmil
NMR structure of C-terminal domain of human CstF-64
Descriptor: CLEAVAGE STIMULATION FACTOR 64 KDA SUBUNIT
Authors:Qu, X, Perez-Canadillas, J.M, Agrawal, S, De Baecke, J, Cheng, H, Varani, G, Moore, C.
Deposit date:2006-10-27
Release date:2006-11-06
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The C-Terminal Domains of Vertebrate Cstf-64 and its Yeast Orthologue RNA15 Form a New Structure Critical for Mrna 3'-End Processing.
J.Biol.Chem., 282, 2007
2KM4
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BU of 2km4 by Molmil
Solution structure of Rtt103 CTD interacting domain
Descriptor: Regulator of Ty1 transposition protein 103
Authors:Lunde, B.M, Reichow, S, Kim, M, Leeper, T.C, Becker, R, Buratowski, S, Meinhart, A, Varani, G.
Deposit date:2009-07-20
Release date:2010-09-08
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:Cooperative interaction of transcription termination factors with the RNA polymerase II C-terminal domain.
Nat.Struct.Mol.Biol., 17, 2010
2KE0
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BU of 2ke0 by Molmil
Solution structure of peptidyl-prolyl cis-trans isomerase from Burkholderia pseudomallei
Descriptor: Peptidyl-prolyl cis-trans isomerase
Authors:Zheng, S, Leeper, T, Napuli, A, Nakazawa, S.H, Varani, G, Seattle Structural Genomics Center for Infectious Disease (SSGCID)
Deposit date:2009-01-21
Release date:2009-03-03
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:The structure of a Burkholderia pseudomallei immunophilin-inhibitor complex reveals new approaches to antimicrobial development.
Biochem.J., 437, 2011
2K8Q
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BU of 2k8q by Molmil
NMR Structure of Shq1p N-terminal domain
Descriptor: Protein SHQ1
Authors:Godin, K.S, Varani, G.
Deposit date:2008-09-18
Release date:2009-05-05
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:The box H/ACA snoRNP assembly factor Shq1p is a chaperone protein homologous to Hsp90 cochaperones that binds to the Cbf5p enzyme
J.Mol.Biol., 390, 2009
6BES
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BU of 6bes by Molmil
Solution structure of de novo macrocycle design11_ss
Descriptor: (DAL)Q(DPR)(DCY)(DLY)DS(DTY)(DCY)P(DSN)
Authors:Shortridge, M.D, Hosseinzadeh, P, Pardo-Avila, F, Varani, G, Baker, D.
Deposit date:2017-10-25
Release date:2017-12-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BF3
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BU of 6bf3 by Molmil
Solution structure of de novo macrocycle design7.3a
Descriptor: QDP(DPR)K(2TL)(DAS)
Authors:Shortridge, M.D, Hosseinzadeh, P, Pardo-Avila, F, Varani, G, Baker, D.
Deposit date:2017-10-25
Release date:2018-01-10
Last modified:2023-11-15
Method:SOLUTION NMR
Cite:Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BE7
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BU of 6be7 by Molmil
Solution structure of de novo macrocycle Design8.1
Descriptor: DDPT(DPR)(DAR)Q(DGN)
Authors:Shortridge, M.D, Hosseinzadeh, P, Pardo-Avila, F, Varani, G, Baker, D.
Deposit date:2017-10-24
Release date:2018-01-03
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017
6BEN
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BU of 6ben by Molmil
Solution structure of de novo macrocycle design8.2
Descriptor: (DAR)Q(DPR)(DGN)R(DGL)PQ
Authors:Shortridge, M.D, Hosseinzadeh, P, Pardo-Avila, F, Varani, G, Baker, B.
Deposit date:2017-10-25
Release date:2017-12-27
Last modified:2023-06-14
Method:SOLUTION NMR
Cite:Comprehensive computational design of ordered peptide macrocycles.
Science, 358, 2017

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