1XXA
| C-TERMINAL DOMAIN OF ESCHERICHIA COLI ARGININE REPRESSOR/ L-ARGININE COMPLEX; PB DERIVATIVE | Descriptor: | ARGININE, ARGININE REPRESSOR, LEAD (II) ION | Authors: | Van Duyne, G.D, Ghosh, G, Maas, W.K, Sigler, P.B. | Deposit date: | 1995-11-03 | Release date: | 1996-03-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the oligomerization and L-arginine binding domain of the arginine repressor of Escherichia coli. J.Mol.Biol., 256, 1996
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1XXB
| C-TERMINAL DOMAIN OF ESCHERICHIA COLI ARGININE REPRESSOR/ L-ARGININE COMPLEX | Descriptor: | ARGININE, ARGININE REPRESSOR | Authors: | Van Duyne, G.D, Ghosh, G, Maas, W.K, Sigler, P.B. | Deposit date: | 1995-11-03 | Release date: | 1996-03-08 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure of the oligomerization and L-arginine binding domain of the arginine repressor of Escherichia coli. J.Mol.Biol., 256, 1996
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1XXC
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1FKB
| ATOMIC STRUCTURE OF THE RAPAMYCIN HUMAN IMMUNOPHILIN FKBP-12 COMPLEX | Descriptor: | FK506 BINDING PROTEIN, RAPAMYCIN IMMUNOSUPPRESSANT DRUG | Authors: | Van Duyne, G.D, Standaert, R.F, Schreiber, S.L, Clardy, J.C. | Deposit date: | 1992-07-02 | Release date: | 1993-10-31 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Atomic Structure of the Rapamycin Human Immunophilin Fkbp-12 Complex J.Am.Chem.Soc., 113, 1991
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5HOT
| Structural Basis for Inhibitor-Induced Aggregation of HIV-1 Integrase | Descriptor: | (2S)-tert-butoxy[4-(8-fluoro-5-methyl-3,4-dihydro-2H-chromen-6-yl)-2-methyl-1-oxo-1,2-dihydroisoquinolin-3-yl]ethanoic acid, Integrase | Authors: | Gupta, K, Turkki, V, Sherrill-Mix, S, Hwang, Y, Eilers, G, Taylor, L, McDanal, C, Wang, P, Temelkoff, D, Nolte, R, Velthuisen, E, Jeffrey, J, Van Duyne, G.D, Bushman, F.D. | Deposit date: | 2016-01-19 | Release date: | 2016-12-14 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (4.4 Å) | Cite: | Structural Basis for Inhibitor-Induced Aggregation of HIV Integrase. PLoS Biol., 14, 2016
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5CRX
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5UAE
| Crystal structure of the coiled-coil domain from Listeria Innocua Phage Integrase (Trigonal Form) | Descriptor: | CITRATE ANION, Putative integrase | Authors: | Gupta, K, Sharp, R, Yuan, J.B, Van Duyne, G.D. | Deposit date: | 2016-12-19 | Release date: | 2017-05-24 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Coiled-coil interactions mediate serine integrase directionality. Nucleic Acids Res., 45, 2017
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5UDO
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5U96
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6DNW
| Sequence Requirements of the Listeria innocua prophage attP site | Descriptor: | DNA (26-MER), Putative integrase [Bacteriophage A118], ZINC ION | Authors: | Li, H, Sharp, R, Rutherford, K, Gupta, K, Van Duyne, G.D. | Deposit date: | 2018-06-08 | Release date: | 2018-10-03 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.849 Å) | Cite: | Serine Integrase attP Binding and Specificity. J. Mol. Biol., 430, 2018
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5E6F
| Canarypox virus resolvase | Descriptor: | CNPV261 Holliday junction resolvase protein, D(-)-TARTARIC ACID, MAGNESIUM ION | Authors: | Li, H, Hwang, Y, Perry, K, Bushman, F.D, Van Duyne, G.D. | Deposit date: | 2015-10-09 | Release date: | 2016-03-30 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structure and Metal Binding Properties of a Poxvirus Resolvase. J.Biol.Chem., 291, 2016
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4CRX
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3C29
| Cre-loxP Synaptic structure | Descriptor: | LoxP DNA, chain C,, chain D,F, ... | Authors: | Ghosh, K, Van Duyne, G.D. | Deposit date: | 2008-01-24 | Release date: | 2009-02-17 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Synapsis study in detail To be Published
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3C28
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3BVP
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1P27
| Crystal Structure of the Human Y14/Magoh complex | Descriptor: | Mago nashi protein homolog, RNA-binding protein 8A | Authors: | Lau, C.K, Diem, M.D, Dreyfuss, G, Van Duyne, G.D. | Deposit date: | 2003-04-14 | Release date: | 2003-08-19 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure of the y14-magoh core of the exon junction complex. Curr.Biol., 13, 2003
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1CRX
| CRE RECOMBINASE/DNA COMPLEX REACTION INTERMEDIATE I | Descriptor: | CRE RECOMBINASE, DNA (5'-D(*AP*TP*AP*TP*GP*CP*TP*AP*TP*AP*CP*GP*AP*AP*GP*TP*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*CP*TP*TP*CP*GP*TP*AP*TP*AP*G)-3'), ... | Authors: | Guo, F, Gopaul, D.N, Van Duyne, G.D. | Deposit date: | 1997-07-02 | Release date: | 1998-10-14 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structure of Cre recombinase complexed with DNA in a site-specific recombination synapse. Nature, 389, 1997
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1B4B
| STRUCTURE OF THE OLIGOMERIZATION DOMAIN OF THE ARGININE REPRESSOR FROM BACILLUS STEAROTHERMOPHILUS | Descriptor: | ARGININE, ARGININE REPRESSOR | Authors: | Ni, J, Sakanyan, V, Charlier, D, Glansdorff, N, Van Duyne, G.D. | Deposit date: | 1998-12-18 | Release date: | 1999-06-15 | Last modified: | 2023-08-02 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of the arginine repressor from Bacillus stearothermophilus. Nat.Struct.Biol., 6, 1999
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1B4A
| STRUCTURE OF THE ARGININE REPRESSOR FROM BACILLUS STEAROTHERMOPHILUS | Descriptor: | ARGININE REPRESSOR | Authors: | Ni, J, Sakanyan, V, Charlier, D, Glansdorff, N, Van Duyne, G.D. | Deposit date: | 1998-12-18 | Release date: | 1999-06-15 | Last modified: | 2024-05-22 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Structure of the arginine repressor from Bacillus stearothermophilus. Nat.Struct.Biol., 6, 1999
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3IGC
| Smallpox virus topoisomerase-DNA transition state | Descriptor: | 5'-D(*AP*TP*TP*CP*C)-3', 5'-D(*CP*GP*GP*AP*AP*TP*AP*AP*GP*GP*GP*CP*GP*AP*CP*A)-3', 5'-D(*GP*TP*GP*TP*CP*GP*CP*CP*CP*TP*T)-3', ... | Authors: | Perry, K, Hwang, Y, Bushman, F.D, Van Duyne, G.D. | Deposit date: | 2009-07-27 | Release date: | 2010-03-02 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Insights from the Structure of a Smallpox Virus Topoisomerase-DNA Transition State Mimic. Structure, 18, 2010
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3MGV
| Cre recombinase-DNA transition state | Descriptor: | DNA (5'-D(*CP*AP*TP*AP*TP*GP*CP*TP*AP*TP*AP*CP*GP*AP*AP*GP*TP*TP*AP*T)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*CP*TP*TP*CP*GP*TP*AP*TP*AP*G)-3'), Recombinase cre, ... | Authors: | Gibb, B.P, Gupta, K, Ghosh, K, Sharp, R, Chen, J, Van Duyne, G.D. | Deposit date: | 2010-04-07 | Release date: | 2010-05-26 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | Requirements for catalysis in the Cre recombinase active site. Nucleic Acids Res., 38, 2010
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1XNS
| Peptide trapped Holliday junction intermediate in Cre-loxP recombination | Descriptor: | Recombinase CRE, loxP DNA | Authors: | Ghosh, K, Lau, C.K, Guo, F, Segall, A.M, Van Duyne, G.D. | Deposit date: | 2004-10-05 | Release date: | 2004-12-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Peptide trapping of the Holliday junction intermediate in Cre-loxP site-specific recombination. J.Biol.Chem., 280, 2005
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1XO0
| High resolution structure of the holliday junction intermediate in cre-loxp site-specific recombination | Descriptor: | Recombinase CRE, loxP | Authors: | Ghosh, K, Lau, C.K, Guo, F, Segall, A.M, Van Duyne, G.D. | Deposit date: | 2004-10-05 | Release date: | 2004-12-14 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Peptide trapping of the Holliday junction intermediate in Cre-loxP site-specific recombination. J.Biol.Chem., 280, 2005
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1Y96
| crystal structure of the Gemin6/Gemin7 heterodimer from the human SMN complex | Descriptor: | Gem-associated protein 6, Gem-associated protein 7 | Authors: | Ma, Y, Dostie, J, Dreyfuss, G, Van Duyne, G.D. | Deposit date: | 2004-12-14 | Release date: | 2005-06-21 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.002 Å) | Cite: | The Gemin6-Gemin7 Heterodimer from the Survival of Motor Neurons Complex Has an Sm Protein-like Structure. Structure, 13, 2005
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4RG5
| Crystal Structure of S. Pombe SMN YG-Dimer | Descriptor: | MALONATE ION, Maltose-binding periplasmic protein, Survival Motor Neuron protein chimera, ... | Authors: | Gupta, K, Martin, R.S, Sarachan, K.L, Sharp, B, Van Duyne, G.D. | Deposit date: | 2014-09-29 | Release date: | 2015-07-01 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | Oligomeric Properties of Survival Motor NeuronGemin2 Complexes. J.Biol.Chem., 290, 2015
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