5J3Q
 
 | | Crystal structure of S. pombe Dcp1:Edc1 mRNA decapping complex | | 分子名称: | Edc1, mRNA-decapping enzyme subunit 1 | | 著者 | Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E. | | 登録日 | 2016-03-31 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | | 主引用文献 | Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation.
Nat.Struct.Mol.Biol., 23, 2016
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5J3Y
 | | Crystal structure of S. pombe Dcp2:Dcp1 mRNA decapping complex | | 分子名称: | mRNA decapping complex subunit 2, mRNA-decapping enzyme subunit 1 | | 著者 | Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E. | | 登録日 | 2016-03-31 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.288 Å) | | 主引用文献 | Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation.
Nat.Struct.Mol.Biol., 23, 2016
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5J3T
 | | Crystal structure of S. pombe Dcp2:Dcp1:Edc1 mRNA decapping complex | | 分子名称: | Edc1, FORMIC ACID, MAGNESIUM ION, ... | | 著者 | Valkov, E, Muthukumar, S, Chang, C.T, Jonas, S, Weichenrieder, O, Izaurralde, E. | | 登録日 | 2016-03-31 | | 公開日 | 2016-05-18 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Structure of the Dcp2-Dcp1 mRNA-decapping complex in the activated conformation.
Nat.Struct.Mol.Biol., 23, 2016
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2Y92
 | | Crystal structure of MAL adaptor protein | | 分子名称: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, TOLL/INTERLEUKIN-1 RECEPTOR DOMAIN-CONTAINING ADAPTER PROTEIN, | | 著者 | Valkov, E, Stamp, A, Martin, J.L, Kobe, B. | | 登録日 | 2011-02-11 | | 公開日 | 2011-09-14 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.01 Å) | | 主引用文献 | Crystal Structure of Toll-Like Receptor Adaptor Mal/Tirap Reveals the Molecular Basis for Signal Transduction and Disease Protection.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3DLR
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5C5W
 | | 1.25 A resolution structure of an RNA 20-mer | | 分子名称: | RNA (5'-R(P*CP*CP*UP*GP*AP*GP*UP*UP*CP*AP*AP*UP*UP*CP*UP*AP*GP*CP*G)-3') | | 著者 | Stewart, M, Valkov, E. | | 登録日 | 2015-06-22 | | 公開日 | 2015-10-14 | | 最終更新日 | 2017-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | | 主引用文献 | 1.25 angstrom resolution structure of an RNA 20-mer that binds to the TREX2 complex.
Acta Crystallogr.,Sect.F, 71, 2015
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4WPX
 | | Chaetomium theromophilum TREX2 CID domain complex | | 分子名称: | Cell division control protein 31-like protein, Putative SAC3 family protein, Putative uncharacterized protein | | 著者 | Valkov, E, Stewart, M. | | 登録日 | 2014-10-21 | | 公開日 | 2015-06-17 | | 最終更新日 | 2015-07-15 | | 実験手法 | X-RAY DIFFRACTION (3.31 Å) | | 主引用文献 | Structural Characterization of the Chaetomium thermophilum TREX-2 Complex and its Interaction with the mRNA Nuclear Export Factor Mex67:Mtr2.
Structure, 23, 2015
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6FNY
 | | CRYSTAL STRUCTURE OF A CHOLINE SULFATASE FROM SINORHIZOBIUM MELLILOTI | | 分子名称: | CALCIUM ION, Choline-sulfatase | | 著者 | Valkov, E, Van Loo, B, Hollfelder, F, Hyvonen, M. | | 登録日 | 2018-02-05 | | 公開日 | 2018-02-28 | | 最終更新日 | 2018-04-04 | | 実験手法 | X-RAY DIFFRACTION (2.79 Å) | | 主引用文献 | Structural and Mechanistic Analysis of the Choline Sulfatase from Sinorhizobium melliloti: A Class I Sulfatase Specific for an Alkyl Sulfate Ester.
J. Mol. Biol., 430, 2018
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4UPK
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4AF0
 | | Crystal structure of cryptococcal inosine monophosphate dehydrogenase | | 分子名称: | INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE, INOSINIC ACID, MYCOPHENOLIC ACID, ... | | 著者 | Valkov, E, Stamp, A, Morrow, C.A, Kobe, B, Fraser, J.A. | | 登録日 | 2012-01-15 | | 公開日 | 2012-10-24 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | De Novo GTP Biosynthesis is Critical for Virulence of the Fungal Pathogen Cryptococcus Neoformans
Plos Pathog., 8, 2012
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4WPM
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4WP6
 | | Structure of the Mex67 LRR domain from Chaetomium thermophilum | | 分子名称: | mRNA export protein | | 著者 | Aibara, S, Valkov, E, Lamers, M, Stewart, M. | | 登録日 | 2014-10-17 | | 公開日 | 2015-07-15 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural characterization of the principal mRNA-export factor Mex67-Mtr2 from Chaetomium thermophilum.
Acta Crystallogr.,Sect.F, 71, 2015
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8FY3
 | | Structure of NOT1:NOT10:NOT11 module of the human CCR4-NOT complex | | 分子名称: | CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 10, CCR4-NOT transcription complex subunit 11 | | 著者 | Lea, S.M, Deme, J.C, Raisch, T, Pekovic, F, Valkov, E. | | 登録日 | 2023-01-25 | | 公開日 | 2023-07-26 | | 最終更新日 | 2023-08-02 | | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | | 主引用文献 | Structure and assembly of the NOT10:11 module of the CCR4-NOT complex.
Commun Biol, 6, 2023
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8FY4
 | | Structure of NOT1:NOT10:NOT11 module of the chicken CCR4-NOT complex | | 分子名称: | CCR4-NOT transcription complex subunit 1, CCR4-NOT transcription complex subunit 10, CCR4-NOT transcription complex subunit 11 | | 著者 | Lea, S.M, Deme, J.C, Raisch, T, Levdansky, Y, Valkov, E. | | 登録日 | 2023-01-25 | | 公開日 | 2023-08-30 | | 実験手法 | ELECTRON MICROSCOPY (2.57 Å) | | 主引用文献 | Structure and assembly of the NOT10:11 module of the CCR4-NOT complex.
Commun Biol, 6, 2023
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4WWU
 | | Structure of Mex67:Mtr2 | | 分子名称: | ZINC ION, mRNA export factor MEX67, mRNA transport regulator MTR2 | | 著者 | Aibara, S, Valkov, E, Stewart, M. | | 登録日 | 2014-11-12 | | 公開日 | 2015-02-04 | | 最終更新日 | 2015-02-25 | | 実験手法 | X-RAY DIFFRACTION (3.301 Å) | | 主引用文献 | Domain organization within the nuclear export factor Mex67:Mtr2 generates an extended mRNA binding surface.
Nucleic Acids Res., 43, 2015
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5T47
 | | Crystal structure of the D. melanogaster eIF4E-eIF4G complex | | 分子名称: | Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4G, isoform A, ... | | 著者 | Gruener, S, Peter, D, Weber, R, Wohlbold, L, Chung, M.-Y, Weichenrieder, O, Valkov, E, Igreja, C, Izaurralde, E. | | 登録日 | 2016-08-29 | | 公開日 | 2016-10-26 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation.
Mol.Cell, 64, 2016
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5T46
 | | Crystal structure of the human eIF4E-eIF4G complex | | 分子名称: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4 gamma 1, Eukaryotic translation initiation factor 4E, ... | | 著者 | Gruener, S, Peter, D, Weber, R, Wohlbold, L, Chung, M.-Y, Weichenrieder, O, Valkov, E, Igreja, C, Izaurralde, E. | | 登録日 | 2016-08-29 | | 公開日 | 2016-10-26 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation.
Mol.Cell, 64, 2016
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5T48
 | | Crystal structure of the D. melanogaster eIF4E-eIF4G complex without lateral contact | | 分子名称: | 7-METHYL-GUANOSINE-5'-TRIPHOSPHATE, Eukaryotic translation initiation factor 4E, Eukaryotic translation initiation factor 4G, ... | | 著者 | Gruener, S, Peter, D, Weber, R, Wohlbold, L, Chung, M.-Y, Weichenrieder, O, Valkov, E, Igreja, C, Izaurralde, E. | | 登録日 | 2016-08-29 | | 公開日 | 2016-10-26 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | The Structures of eIF4E-eIF4G Complexes Reveal an Extended Interface to Regulate Translation Initiation.
Mol.Cell, 64, 2016
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6S8R
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6S8S
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5FU7
 | | drosophila nanos NBR peptide bound to the NOT module of the human CCR4-NOT complex | | 分子名称: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3, ... | | 著者 | Raisch, T, Bhandari, D, Sabath, K, Helms, S, Valkov, E, Weichenrieder, O, Izaurralde, E. | | 登録日 | 2016-01-21 | | 公開日 | 2016-03-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Distinct Modes of Recruitment of the Ccr4-not Complex by Drosophila and Vertebrate Nanos
Embo J., 35, 2016
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5FU6
 | | NOT module of the human CCR4-NOT complex (Crystallization mutant) | | 分子名称: | CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 1, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 2, CCR4-NOT TRANSCRIPTION COMPLEX SUBUNIT 3 | | 著者 | Raisch, T, Bhandari, D, Sabath, K, Helms, S, Valkov, E, Weichenrieder, O, Izaurralde, E. | | 登録日 | 2016-01-21 | | 公開日 | 2016-03-23 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Distinct Modes of Recruitment of the Ccr4-not Complex by Drosophila and Vertebrate Nanos
Embo J., 35, 2016
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4LJ0
 | | Nab2 Zn fingers complexed with polyadenosine | | 分子名称: | ACETATE ION, MAGNESIUM ION, Nab2, ... | | 著者 | Stewart, M, Kuhlmann, S.I, Valkov, E. | | 登録日 | 2013-07-04 | | 公開日 | 2013-10-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.15 Å) | | 主引用文献 | Structural basis for the molecular recognition of polyadenosine RNA by Nab2 Zn fingers.
Nucleic Acids Res., 42, 2014
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4X2O
 | | Sac3N peptide bound to Mex67:Mtr2 | | 分子名称: | Putative SAC3 family protein, Putative mRNA export protein, Putative uncharacterized protein | | 著者 | Aibara, S, Valkov, E, Stewart, M. | | 登録日 | 2014-11-26 | | 公開日 | 2015-06-17 | | 最終更新日 | 2015-07-15 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural Characterization of the Chaetomium thermophilum TREX-2 Complex and its Interaction with the mRNA Nuclear Export Factor Mex67:Mtr2.
Structure, 23, 2015
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4WP5
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