1S0V
 
 | | Structural basis for substrate selection by T7 RNA polymerase | | 分子名称: | 5'-D(*G*GP*GP*AP*AP*TP*CP*GP*AP*TP*AP*TP*CP*GP*CP*CP*GP*C)-3', 5'-D(*GP*TP*CP*GP*AP*TP*TP*CP*CP*C)-3', 5'-R(*AP*AP*CP*U*GP*CP*GP*GP*CP*GP*AP*U)-3', ... | | 著者 | Temiakov, D, Patlan, V, Anikin, M, McAllister, W.T, Yokoyama, S, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2004-01-05 | | 公開日 | 2004-02-24 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural basis for substrate selection by t7 RNA polymerase.
Cell(Cambridge,Mass.), 116, 2004
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2A6H
 | | Crystal structure of the T. thermophilus RNA polymerase holoenzyme in complex with antibiotic sterptolydigin | | 分子名称: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | | 著者 | Temiakov, D, Zenkin, N, Vassylyeva, M.N, Perederina, A, Tahirov, T.H, Savkina, M, Zorov, S, Nikiforov, V, Igarashi, N, Matsugaki, N, Wakatsuki, S, Severinov, K, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-07-02 | | 公開日 | 2005-09-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural basis of transcription inhibition by antibiotic streptolydigin.
Mol.Cell, 19, 2005
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8T7E
 | | Cryo-EM structure of the Backtracking Initiation Complex (VII) of Human Mitochondrial DNA Polymerase Gamma | | 分子名称: | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... | | 著者 | Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D. | | 登録日 | 2023-06-20 | | 公開日 | 2024-01-10 | | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | | 主引用文献 | Structural basis for DNA proofreading.
Nat Commun, 14, 2023
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3SPA
 | | Crystal Structure of Human Mitochondrial RNA Polymerase | | 分子名称: | CHLORIDE ION, DNA-directed RNA polymerase, mitochondrial, ... | | 著者 | Ringel, R, Sologub, M, Morozov, Y.I, Litonin, D, Cramer, P, Temiakov, D. | | 登録日 | 2011-07-01 | | 公開日 | 2011-09-28 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Structure of human mitochondrial RNA polymerase
Nature, 478, 2011
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4BOC
 | | Structure of mitochondrial RNA polymerase elongation complex | | 分子名称: | 5'-D(*CP*AP*TP*GP*GP*GP*GP*TP*AP*AP*TP*TP*AP*TP *TP*TP*CP*GP*AP*CP*GP*CP*CP*AP*GP*AP*CP*G)-3', 5'-D(*CP*GP*TP*CP*TP*GP*GP*CP*GP*TP*GP*CP*GP*CP *GP*CP*CP*GP*CP*TP*AP*CP*CP*CP*CP*AP*TP*G)-3', 5'-R(*AP*GP*UP*CP*UP*GP*CP*GP*GP*CP*GP*CP*GP*CP)-3', ... | | 著者 | Schwinghammer, K, Cheung, A, Morozov, Y, Agaronyan, K, Temiakov, D, Cramer, P. | | 登録日 | 2013-05-18 | | 公開日 | 2013-09-25 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Structure of Human Mitochondrial RNA Polymerase Elongation Complex
Nat.Struct.Mol.Biol., 20, 2013
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7A9X
 | | Structure of yeast Rmd9p in complex with 16nt target RNA | | 分子名称: | CHLORIDE ION, Protein RMD9, mitochondrial, ... | | 著者 | Hillen, H.S, Markov, D.A, Ireneusz, W.D, Hofmann, K.B, Cowan, A.T, Jones, J.L, Temiakov, D, Cramer, P, Anikin, M. | | 登録日 | 2020-09-02 | | 公開日 | 2021-04-07 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | The pentatricopeptide repeat protein Rmd9 recognizes the dodecameric element in the 3'-UTRs of yeast mitochondrial mRNAs.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7A9W
 | | Structure of yeast Rmd9p in complex with 20nt target RNA | | 分子名称: | CHLORIDE ION, Protein RMD9, mitochondrial, ... | | 著者 | Hillen, H.S, Markov, D.A, Ireneusz, W.D, Hofmann, K.B, Cowan, A.T, Jones, J.L, Temiakov, D, Cramer, P, Anikin, M. | | 登録日 | 2020-09-02 | | 公開日 | 2021-04-07 | | 最終更新日 | 2021-05-05 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | The pentatricopeptide repeat protein Rmd9 recognizes the dodecameric element in the 3'-UTRs of yeast mitochondrial mRNAs.
Proc.Natl.Acad.Sci.USA, 118, 2021
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8G5L
 | | Cryo-EM structure of the Primer Separation Complex (IX) of Human Mitochondrial DNA Polymerase Gamma | | 分子名称: | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... | | 著者 | Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D. | | 登録日 | 2023-02-13 | | 公開日 | 2024-01-10 | | 実験手法 | ELECTRON MICROSCOPY (3 Å) | | 主引用文献 | Structural basis for DNA proofreading.
Nat Commun, 14, 2023
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8G5I
 | | Cryo-EM structure of the Mismatch Sensing Complex (I) of Human Mitochondrial DNA Polymerase Gamma | | 分子名称: | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... | | 著者 | Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D. | | 登録日 | 2023-02-13 | | 公開日 | 2024-01-10 | | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | | 主引用文献 | Structural basis for DNA proofreading.
Nat Commun, 14, 2023
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8G5O
 | | Cryo-EM structure of the Guide loop Engagement Complex (IV) of Human Mitochondrial DNA Polymerase Gamma | | 分子名称: | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... | | 著者 | Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D. | | 登録日 | 2023-02-13 | | 公開日 | 2024-01-10 | | 実験手法 | ELECTRON MICROSCOPY (2.61 Å) | | 主引用文献 | Structural basis for DNA proofreading.
Nat Commun, 14, 2023
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8G5M
 | | Cryo-EM structure of the Mismatch Locking Complex (III) of Human Mitochondrial DNA Polymerase Gamma | | 分子名称: | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... | | 著者 | Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D. | | 登録日 | 2023-02-13 | | 公開日 | 2024-01-10 | | 実験手法 | ELECTRON MICROSCOPY (2.58 Å) | | 主引用文献 | Structural basis for DNA proofreading.
Nat Commun, 14, 2023
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8G5N
 | | Cryo-EM structure of the Guide loop Engagement Complex (VI) of Human Mitochondrial DNA Polymerase Gamma | | 分子名称: | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... | | 著者 | Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D. | | 登録日 | 2023-02-13 | | 公開日 | 2024-01-10 | | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | | 主引用文献 | Structural basis for DNA proofreading.
Nat Commun, 14, 2023
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8G5K
 | | Cryo-EM structure of the Wedge Alignment Complex (VIII) of Human Mitochondrial DNA Polymerase Gamma | | 分子名称: | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... | | 著者 | Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D. | | 登録日 | 2023-02-13 | | 公開日 | 2024-01-10 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Structural basis for DNA proofreading.
Nat Commun, 14, 2023
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8G5P
 | | Cryo-EM structure of the Guide loop Engagement Complex (V) of Human Mitochondrial DNA Polymerase Gamma | | 分子名称: | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... | | 著者 | Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D. | | 登録日 | 2023-02-13 | | 公開日 | 2024-01-10 | | 実験手法 | ELECTRON MICROSCOPY (2.78 Å) | | 主引用文献 | Structural basis for DNA proofreading.
Nat Commun, 14, 2023
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8G5J
 | | Cryo-EM structure of the Mismatch Uncoupling Complex (II) of Human Mitochondrial DNA Polymerase Gamma | | 分子名称: | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... | | 著者 | Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D. | | 登録日 | 2023-02-13 | | 公開日 | 2024-01-10 | | 実験手法 | ELECTRON MICROSCOPY (2.63 Å) | | 主引用文献 | Structural basis for DNA proofreading.
Nat Commun, 14, 2023
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6ERQ
 | | Structure of the human mitochondrial transcription initiation complex at the HSP promoter | | 分子名称: | DNA-directed RNA polymerase, mitochondrial, Dimethyladenosine transferase 2, ... | | 著者 | Hillen, H.S, Morozov, Y.I, Sarfallah, A, Temiakov, D, Cramer, P. | | 登録日 | 2017-10-18 | | 公開日 | 2017-11-15 | | 最終更新日 | 2018-01-31 | | 実験手法 | X-RAY DIFFRACTION (4.5 Å) | | 主引用文献 | Structural Basis of Mitochondrial Transcription Initiation.
Cell, 171, 2017
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6ERO
 | | Structure of human TFB2M | | 分子名称: | CHLORIDE ION, Dimethyladenosine transferase 2, mitochondrial,Dimethyladenosine transferase 2, ... | | 著者 | Hillen, H.S, Morozov, Y.I, Sarfallah, A, Temiakov, D, Cramer, P. | | 登録日 | 2017-10-18 | | 公開日 | 2017-11-15 | | 最終更新日 | 2018-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural Basis of Mitochondrial Transcription Initiation.
Cell, 171, 2017
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6ERP
 | | Structure of the human mitochondrial transcription initiation complex at the LSP promoter | | 分子名称: | DNA-directed RNA polymerase, mitochondrial, Dimethyladenosine transferase 2, ... | | 著者 | Hillen, H.S, Morozov, Y.I, Sarfallah, A, Temiakov, D, Cramer, P. | | 登録日 | 2017-10-18 | | 公開日 | 2017-11-15 | | 最終更新日 | 2018-01-31 | | 実験手法 | X-RAY DIFFRACTION (4.502 Å) | | 主引用文献 | Structural Basis of Mitochondrial Transcription Initiation.
Cell, 171, 2017
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5OL9
 | | Structure of human mitochondrial transcription elongation factor (TEFM) N-terminal domain | | 分子名称: | ACETATE ION, Transcription elongation factor, mitochondrial | | 著者 | Hillen, H.S, Parshin, A.V, Agaronyan, K, Morozov, Y, Graber, J.J, Chernev, A, Schwinghammer, K, Urlaub, H, Anikin, M, Cramer, P, Temiakov, D. | | 登録日 | 2017-07-27 | | 公開日 | 2017-10-18 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.302 Å) | | 主引用文献 | Mechanism of Transcription Anti-termination in Human Mitochondria.
Cell, 171, 2017
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5OLA
 | | Structure of mitochondrial transcription elongation complex in complex with elongation factor TEFM | | 分子名称: | DNA (30-MER), DNA (5'-D(P*AP*TP*GP*GP*TP*GP*TP*AP*AP*CP*GP*CP*CP*AP*GP*AP*CP*GP*AP*AP*C)-3'), DNA-directed RNA polymerase, ... | | 著者 | Hillen, H.S, Parshin, A.V, Agaronyan, K, Morozov, Y, Graber, J.J, Chernev, A, Schwinghammer, K, Urlaub, H, Anikin, M, Cramer, P, Temiakov, D. | | 登録日 | 2017-07-27 | | 公開日 | 2017-10-18 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.904 Å) | | 主引用文献 | Mechanism of Transcription Anti-termination in Human Mitochondria.
Cell, 171, 2017
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5OL8
 | | Structure of human mitochondrial transcription elongation factor (TEFM) C-terminal domain | | 分子名称: | GLYCEROL, Transcription elongation factor, mitochondrial | | 著者 | Hillen, H.S, Parshin, A.V, Agaronyan, K, Morozov, Y, Graber, J.J, Chernev, A, Schwinghammer, K, Urlaub, H, Anikin, M, Cramer, P, Temiakov, D. | | 登録日 | 2017-07-27 | | 公開日 | 2017-10-18 | | 最終更新日 | 2017-11-29 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Mechanism of Transcription Anti-termination in Human Mitochondria.
Cell, 171, 2017
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1H38
 | | Structure of a T7 RNA polymerase elongation complex at 2.9A resolution | | 分子名称: | 5'-D(*GP*GP*GP*AP*AP*TP*CP*GP*AP*CP *AP*TP*CP*GP*CP*CP*GP*C)-3', 5'-D(*GP*TP*CP*GP*AP*TP*TP*CP*CP*CP)-3', 5'-R(*AP*AP*CP*UP*GP*CP*GP*GP*CP*GP *AP*U)-3', ... | | 著者 | Tahirov, T.H, Temyakov, D, Anikin, M, Patlan, V, McAllister, W.T, Vassylyev, D.G, Yokoyama, S. | | 登録日 | 2002-08-24 | | 公開日 | 2002-11-20 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structure of a T7 RNA Polymerase Elongation Complex at 2.9 A Resolution
Nature, 420, 2002
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2A6E
 | | Crystal structure of the T. Thermophilus RNA polymerase holoenzyme | | 分子名称: | DNA-directed RNA polymerase alpha chain, DNA-directed RNA polymerase beta chain, DNA-directed RNA polymerase beta' chain, ... | | 著者 | Artsimovitch, I, Vassylyeva, M.N, Svetlov, D, Svetlov, V, Perederina, A, Igarashi, N, Matsugaki, N, Wakatsuki, S, Tahirov, T.H, Vassylyev, D.G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | 登録日 | 2005-07-02 | | 公開日 | 2005-09-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Allosteric modulation of the RNA polymerase catalytic reaction is an essential component of transcription control by rifamycins.
Cell(Cambridge,Mass.), 122, 2005
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