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Three-dimensional reconstruction of human LRP6 ectodomain complexed with Dkk1
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者	Matoba, K, Mihara, E, Tamura-Kawakami, K, Hirai, H, Thompson, S, Iwasaki, K, Takagi, J.
登録日	2016-06-29
公開日	2017-01-18
最終更新日	2020-07-29
実験手法	ELECTRON MICROSCOPY (21 Å)
主引用文献	Conformational Freedom of the LRP6 Ectodomain Is Regulated by N-glycosylation and the Binding of the Wnt Antagonist Dkk1 Cell Rep, 18, 2017

4YNY

Crystal structure of monoclonal anti-human podoplanin antibody NZ-1
分子名称:	Heavy chain of antigen binding fragment, Fab, Light chain of antigen binding fragment
著者	Fujii, Y, Kitago, Y, Arimori, T, Takagi, J.
登録日	2015-03-11
公開日	2016-03-02
最終更新日	2023-11-08
実験手法	X-RAY DIFFRACTION (1.584 Å)
主引用文献	Tailored placement of a turn-forming PA tag into the structured domain of a protein to probe its conformational state J.Cell.Sci., 129, 2016

5B4Y

Crystal structure of the LA12 fragment of ApoER2
分子名称:	CALCIUM ION, Low-density lipoprotein receptor-related protein 8
著者	Nogi, T, Tabata, S, Hirai, H, Yasui, N, Takagi, J.
登録日	2016-04-20
公開日	2017-04-26
最終更新日	2023-11-08
実験手法	X-RAY DIFFRACTION (1.9 Å)
主引用文献	Crystal structure of the ectodomain from a LDLR close homologue in complex with its physiological ligand. To Be Published

5AUM

Crystal structure of a Fab fragment with the ligand peptide
分子名称:	Heavy chain of Fab fragment, Light chain of Fab fragment, ZINC ION, ...
著者	Kitago, Y, Takagi, J.
登録日	2015-04-30
公開日	2016-08-10
最終更新日	2023-11-08
実験手法	X-RAY DIFFRACTION (2.05 Å)
主引用文献	Crystal structure of a Fab fragment with the ligand peptide To Be Published

5B4W

Crystal structure of Plexin inhibitor complex
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, Plexin-B1, Synthesized cyclic peptide
著者	Matsunaga, Y, Kitago, Y, Arimori, T, Takagi, J.
登録日	2016-04-19
公開日	2016-12-28
最終更新日	2023-11-15
実験手法	X-RAY DIFFRACTION (2.6 Å)
主引用文献	Allosteric Inhibition of a Semaphorin 4D Receptor Plexin B1 by a High-Affinity Macrocyclic Peptide Cell Chem Biol, 23, 2016

5B4X

Crystal structure of the ApoER2 ectodomain in complex with the Reelin R56 fragment
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Low density lipoprotein receptor-related protein 8, ...
著者	Yasui, N, Hirai, H, Yamashita, K, Takagi, J, Nogi, T.
登録日	2016-04-20
公開日	2017-04-26
最終更新日	2020-07-29
実験手法	X-RAY DIFFRACTION (3.2 Å)
主引用文献	Crystal structure of the ectodomain from a LDLR close homologue in complex with its physiological ligand. To Be Published

2DDU

Crystal structure of the third repeat domain of reelin
分子名称:	CALCIUM ION, CHLORIDE ION, MAGNESIUM ION, ...
著者	Nogi, T, Yasui, N, Takagi, J.
登録日	2006-02-03
公開日	2006-09-26
最終更新日	2011-10-05
実験手法	X-RAY DIFFRACTION (2.05 Å)
主引用文献	Structure of a signaling-competent reelin fragment revealed by X-ray crystallography and electron tomography Embo J., 25, 2006

6LZ9

t8E4 antibody Fab complexed with the active form of HGF
分子名称:	Heavy chain of t8E4 Fab fragment, Hepatocyte growth factor, Light chain of t8E4 Fab fragment
著者	Kitago, Y, Umitsu, M, Takagi, J.
登録日	2020-02-18
公開日	2020-03-11
最終更新日	2023-11-29
実験手法	X-RAY DIFFRACTION (2.8 Å)
主引用文献	t8E4 antibody Fab complexed with the active form of HGF To Be Published

7VF3

Plexin B1 extracellular fragment in complex with lasso-grafted PB1m7 peptide
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, DI(HYDROXYETHYL)ETHER, Plexin-B1, ...
著者	Sugano, N.N, Hirata, K, Yamashita, K, Yamamoto, M, Arimori, T, Takagi, J.
登録日	2021-09-10
公開日	2022-08-17
最終更新日	2023-11-29
実験手法	X-RAY DIFFRACTION (2.29 Å)
主引用文献	De novo Fc-based receptor dimerizers differentially modulate PlexinB1 function. Structure, 30, 2022

7XOL

Cryo-EM structure of single empty ring 2 (SER2) of GroEL-UGT1A complex at 3.2 Ang. resolution
分子名称:	Chaperonin GroEL
著者	Stapleton, K, Takagi, J, Mizohata, E.
登録日	2022-05-01
公開日	2023-05-03
実験手法	ELECTRON MICROSCOPY (3.26 Å)
主引用文献	Unmasking GroEL: Structure, dynamics, and substrate binding revealed by single-particle cryo-EM To Be Published

7XOS

Cryo-EM structure of occupied ring subunit 4 (OR4) of GroEL from GroEL-UGT1A double occupied ring complex
分子名称:	Chaperonin GroEL
著者	Stapleton, K, Takagi, J, Mizohata, E.
登録日	2022-05-01
公開日	2023-05-03
実験手法	ELECTRON MICROSCOPY (3.2 Å)
主引用文献	Unmasking GroEL: Structure, dynamics, and substrate binding revealed by single-particle cryo-EM To Be Published

7XOQ

Cryo-EM structure of occupied ring subunit 2 (OR2) of GroEL from GroEL-UGT1A double occupied ring complex
分子名称:	Chaperonin GroEL
著者	Stapleton, K, Takagi, J, Mizohata, E.
登録日	2022-05-01
公開日	2023-05-03
実験手法	ELECTRON MICROSCOPY (3.3 Å)
主引用文献	Unmasking GroEL: Structure, dynamics, and substrate binding revealed by single-particle cryo-EM To Be Published

7XOK

Cryo-EM structure of double occupied ring (DOR) of GroEL-UGT1A complex at 2.7 Ang. resolution
分子名称:	Chaperonin GroEL
著者	Stapleton, K, Takagi, J, Mizohata, E.
登録日	2022-05-01
公開日	2023-05-03
実験手法	ELECTRON MICROSCOPY (2.7 Å)
主引用文献	Unmasking GroEL: Structure, dynamics, and substrate binding revealed by single-particle cryo-EM To Be Published

7XOP

Cryo-EM structure of occupied ring subunit 1 (OR1) of GroEL from GroEL-UGT1A double occupied ring complex
分子名称:	Chaperonin GroEL
著者	Stapleton, K, Takagi, J, Mizohata, E.
登録日	2022-05-01
公開日	2023-05-03
実験手法	ELECTRON MICROSCOPY (3.2 Å)
主引用文献	Unmasking GroEL: Structure, dynamics, and substrate binding revealed by single-particle cryo-EM To Be Published

7XON

Cryo-EM structure of empty ring subunit 1 (ER1) from single empty ring of GroEL-UGT1A complex
分子名称:	Chaperonin GroEL
著者	Stapleton, K, Takagi, J, Mizohata, E.
登録日	2022-05-01
公開日	2023-05-03
実験手法	ELECTRON MICROSCOPY (3.1 Å)
主引用文献	Unmasking GroEL: Structure, dynamics, and substrate binding revealed by single-particle cryo-EM To Be Published

7XOM

Cryo-EM structure of occupied ring subunit 4 (OR4) of GroEL complexed with polyalanine model of UGT1A from GroEL-UGT1A double occupied ring complex
分子名称:	Chaperonin GroEL, Polyalanine model of UDP-glucuronosyltransferase 1A (UGT1A)
著者	Stapleton, K, Takagi, J, Mizohata, E.
登録日	2022-05-01
公開日	2023-05-03
実験手法	ELECTRON MICROSCOPY (3.2 Å)
主引用文献	Unmasking GroEL: Structure, dynamics, and substrate binding revealed by single-particle cryo-EM To Be Published

7XOR

Cryo-EM structure of occupied ring subunit 3 (OR3) of GroEL from GroEL-UGT1A double occupied ring complex
分子名称:	Chaperonin GroEL
著者	Stapleton, K, Takagi, J, Mizohata, E.
登録日	2022-05-01
公開日	2023-05-03
実験手法	ELECTRON MICROSCOPY (3.3 Å)
主引用文献	Unmasking GroEL: Structure, dynamics, and substrate binding revealed by single-particle cryo-EM To Be Published

7XOJ

Cryo-EM structure of GroEL bound to unfolded substrate (UGT1A) at 2.8 Ang. resolution (Consensus Refinement)
分子名称:	Chaperonin GroEL
著者	Stapleton, K, Takagi, J, Mizohata, E.
登録日	2022-05-01
公開日	2023-05-03
実験手法	ELECTRON MICROSCOPY (2.8 Å)
主引用文献	Unmasking GroEL: Structure, dynamics, and substrate binding revealed by single-particle cryo-EM To Be Published

7XOO

Cryo-EM structure of empty ring subunit 2 (ER2) from GroEL-UGT1A single empty ring complex
分子名称:	Chaperonin GroEL
著者	Stapleton, K, Takagi, J, Mizohata, E.
登録日	2022-05-01
公開日	2023-05-03
実験手法	ELECTRON MICROSCOPY (3 Å)
主引用文献	Unmasking GroEL: Structure, dynamics, and substrate binding revealed by single-particle cryo-EM To Be Published

1L3Y

INTEGRIN EGF-LIKE MODULE 3 FROM THE BETA-2 SUBUNIT
分子名称:	Integrin beta-2:CYSTEINE-RICH MODULE 3
著者	Beglova, N, Blacklow, S.C, Takagi, J, Springer, T.A.
登録日	2002-03-03
公開日	2002-04-01
最終更新日	2022-02-23
実験手法	SOLUTION NMR
主引用文献	Cysteine-rich module structure reveals a fulcrum for integrin rearrangement upon activation. Nat.Struct.Biol., 9, 2002

1MQ8

Crystal structure of alphaL I domain in complex with ICAM-1
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Integrin alpha-L, ...
著者	Shimaoka, M, Xiao, T, Liu, J.-H, Yang, Y, Dong, Y, Jun, C.-D, McCormack, A, Zhang, R, Joachimiak, A, Takagi, J, Wang, J.-H, Springer, T.A.
登録日	2002-09-15
公開日	2003-01-14
最終更新日	2021-10-27
実験手法	X-RAY DIFFRACTION (3.3 Å)
主引用文献	Structures of the aL I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation Cell(Cambridge,Mass.), 112, 2003

1MQA

Crystal structure of high affinity alphaL I domain in the absence of ligand or metal
分子名称:	Integrin alpha-L
著者	Shimaoka, T, Xiao, T, Liu, J.-H, Yang, Y, Dong, Y, Jun, C.-D, Zhang, R, Takagi, J, Wang, J.-H, Springer, T.A.
登録日	2002-09-15
公開日	2003-01-14
最終更新日	2021-10-27
実験手法	X-RAY DIFFRACTION (2.5 Å)
主引用文献	Structures of the aL I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation Cell(Cambridge,Mass.), 112, 2003

1MQ9

Crystal structure of high affinity alphaL I domain with ligand mimetic crystal contact
分子名称:	Integrin alpha-L, MANGANESE (II) ION
著者	Shimaoka, M, Xiao, T, Liu, J.-H, Yang, Y, Dong, Y, Jun, C.-D, McCormack, A, Zhang, R, Joachimiak, A, Takagi, J, Wang, J.-H, Springer, T.A.
登録日	2002-09-15
公開日	2003-01-14
最終更新日	2021-10-27
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Structures of the aL I domain and its complex with ICAM-1 reveal a shape-shifting pathway for integrin regulation Cell(Cambridge,Mass.), 112, 2003

2E26

Crystal structure of two repeat fragment of reelin
分子名称:	2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ACETATE ION, ...
著者	Yasui, N, Nogi, T, Kitao, T, Takagi, J.
登録日	2006-11-08
公開日	2007-05-22
最終更新日	2023-10-25
実験手法	X-RAY DIFFRACTION (2 Å)
主引用文献	Structure of a receptor-binding fragment of reelin and mutational analysis reveal a recognition mechanism similar to endocytic receptors. Proc.Natl.Acad.Sci.Usa, 104, 2007

1IJQ

Crystal Structure of the LDL Receptor YWTD-EGF Domain Pair
分子名称:	LOW-DENSITY LIPOPROTEIN RECEPTOR
著者	Jeon, H, Meng, W, Takagi, J, Eck, M.J, Springer, T.A, Blacklow, S.C.
登録日	2001-04-27
公開日	2001-05-23
最終更新日	2018-04-04
実験手法	X-RAY DIFFRACTION (1.5 Å)
主引用文献	Implications for familial hypercholesterolemia from the structure of the LDL receptor YWTD-EGF domain pair. Nat.Struct.Biol., 8, 2001

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