7S8Z
| |
7S9G
| Room-temperature Human Hsp90a-NTD bound to BIIB021 | Descriptor: | 6-chloro-9-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-9H-purin-2-amine, Heat shock protein HSP 90-alpha, MAGNESIUM ION | Authors: | Stachowski, T.R, Vanarotti, M, Fischer, M. | Deposit date: | 2021-09-21 | Release date: | 2022-08-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Water Networks Repopulate Protein-Ligand Interfaces with Temperature. Angew.Chem.Int.Ed.Engl., 61, 2022
|
|
7S9F
| Cryogenic Human Hsp90a-NTD bound to BIIB021 | Descriptor: | 6-chloro-9-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-9H-purin-2-amine, Heat shock protein HSP 90-alpha, MAGNESIUM ION | Authors: | Stachowski, T.R, Vanarotti, M, Seetharaman, J, Fischer, M. | Deposit date: | 2021-09-20 | Release date: | 2022-08-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Water Networks Repopulate Protein-Ligand Interfaces with Temperature. Angew.Chem.Int.Ed.Engl., 61, 2022
|
|
7S95
| Room-temperature Human Hsp90a-NTD bound to adenine | Descriptor: | ADENINE, Heat shock protein HSP 90-alpha | Authors: | Stachowski, T.R, Vanarotti, M, Lopez, K, Fischer, M. | Deposit date: | 2021-09-20 | Release date: | 2022-08-03 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.71 Å) | Cite: | Water Networks Repopulate Protein-Ligand Interfaces with Temperature. Angew.Chem.Int.Ed.Engl., 61, 2022
|
|
7S9I
| Room-temperature Human Hsp90a-NTD bound to EC144 | Descriptor: | 5-{2-amino-4-chloro-7-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl}-2-methylpent-4-yn-2 -ol, Heat shock protein HSP 90-alpha | Authors: | Stachowski, T.R, Vanarotti, M, Fischer, M. | Deposit date: | 2021-09-21 | Release date: | 2022-08-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Water Networks Repopulate Protein-Ligand Interfaces with Temperature. Angew.Chem.Int.Ed.Engl., 61, 2022
|
|
7S9H
| Cryogenic Human Hsp90a-NTD bound to EC144 | Descriptor: | 5-{2-amino-4-chloro-7-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-7H-pyrrolo[2,3-d]pyrimidin-5-yl}-2-methylpent-4-yn-2 -ol, Heat shock protein HSP 90-alpha, MAGNESIUM ION | Authors: | Stachowski, T.R, Vanarotti, M, Seetharaman, J, Fischer, M. | Deposit date: | 2021-09-21 | Release date: | 2022-08-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Water Networks Repopulate Protein-Ligand Interfaces with Temperature. Angew.Chem.Int.Ed.Engl., 61, 2022
|
|
7S98
| Cryogenic Human Hsp90a-NTD bound to N6M | Descriptor: | Heat shock protein HSP 90-alpha, N-METHYL-9H-PURIN-6-AMINE | Authors: | Stachowski, T.R, Vanarotti, M, Lopez, K, Fischer, M. | Deposit date: | 2021-09-20 | Release date: | 2022-08-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Water Networks Repopulate Protein-Ligand Interfaces with Temperature. Angew.Chem.Int.Ed.Engl., 61, 2022
|
|
7S8Y
| |
7S90
| Cryogenic Human Hsp90a-NTD bound to adenine | Descriptor: | ADENINE, Heat shock protein HSP 90-alpha | Authors: | Stachowski, T.R, Vanarotti, M, Lopez, K, Fischer, M. | Deposit date: | 2021-09-20 | Release date: | 2022-08-03 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Water Networks Repopulate Protein-Ligand Interfaces with Temperature. Angew.Chem.Int.Ed.Engl., 61, 2022
|
|
7S99
| Room-temperature Human Hsp90a-NTD bound to N6M | Descriptor: | Heat shock protein HSP 90-alpha, N-METHYL-9H-PURIN-6-AMINE | Authors: | Stachowski, T.R, Vanarotti, M, Lopez, K, Fischer, M. | Deposit date: | 2021-09-20 | Release date: | 2022-08-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.52 Å) | Cite: | Water Networks Repopulate Protein-Ligand Interfaces with Temperature. Angew.Chem.Int.Ed.Engl., 61, 2022
|
|
1MEL
| CRYSTAL STRUCTURE OF A CAMEL SINGLE-DOMAIN VH ANTIBODY FRAGMENT IN COMPLEX WITH LYSOZYME | Descriptor: | LYSOZYME, VH SINGLE-DOMAIN ANTIBODY | Authors: | Desmyter, A, Transue, T.R, Arbabi Gharoudi, M, Dao Thi, M, Poortmans, F, Hamers, R, Muyldermans, S, Wyns, L. | Deposit date: | 1996-06-06 | Release date: | 1997-06-16 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structure of a camel single-domain VH antibody fragment in complex with lysozyme. Nat.Struct.Biol., 3, 1996
|
|
1N41
| Crystal Structure of Annexin V K27E Mutant | Descriptor: | CALCIUM ION, SULFATE ION, annexin V | Authors: | Mo, Y.D, Campos, B, Mealy, T.R, Commodore, L, Head, J.F, Dedman, J.R, Seaton, B.A. | Deposit date: | 2002-10-30 | Release date: | 2003-02-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Interfacial basic cluster in annexin V couples phospholipid
binding and trimer formation on membrane surfaces J.Biol.Chem., 278, 2003
|
|
1N44
| Crystal Structure of Annexin V R23E Mutant | Descriptor: | Annexin V, CALCIUM ION, SULFATE ION | Authors: | Mo, Y.D, Campos, B, Mealy, T.R, Commodore, L, Head, J.F, Dedman, J.R, Seaton, B.A. | Deposit date: | 2002-10-30 | Release date: | 2003-02-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Interfacial basic cluster in anexin V couples phospholipid binding and trimer formation on membrane surfaces J.Biol.Chem., 278, 2003
|
|
1N42
| Crystal Structure of Annexin V R149E Mutant | Descriptor: | Annexin V, CALCIUM ION, SULFATE ION | Authors: | Mo, Y.D, Campos, B, Mealy, T.R, Commodore, L, Head, J.F, Dedman, J.R, Seaton, B.A. | Deposit date: | 2002-10-30 | Release date: | 2003-02-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Interfacial basic cluster in annexin V couples phospholipid binding and trimer formation on membrane surfaces J.Biol.Chem., 278, 2003
|
|
1NTS
| 5'(dCCPUPCPCPUPUP)3':3'(rAGGAGGAAA)5', where P=propynyl | Descriptor: | 5'-D(*(5PC)P*(5PC)P*(PDU)P*(5PC)P*(5PC)P*(PDU)P*(PDU))-3', 5'-R(*AP*AP*AP*GP*GP*AP*GP*GP*A)-3' | Authors: | Znosko, B.M, Barnes III, T.W, Krugh, T.R, Turner, D.H. | Deposit date: | 2003-01-30 | Release date: | 2003-06-10 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | NMR Studies of DNA Single Strands and DNA:RNA Hybrids With and Without 1-Propynylation at C5 of Oligopyrimidines J.Am.Chem.Soc., 125, 2003
|
|
1OAB
| CRYSTAL STRUCTURE OF THE TYROSINE REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE FROM SACCHAROMYCES CEREVISIAE IN COMPLEX WITH PHOSPHOENOLPYRUVATE AND MANGANESE(II) | Descriptor: | MANGANESE (II) ION, PHOSPHOENOLPYRUVATE, TYROSINE-REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE | Authors: | Koenig, V, Pfeil, A, Heinrich, G, Braus, G.H, Schneider, T.R. | Deposit date: | 2003-01-06 | Release date: | 2004-01-23 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Substrate and Metal Complexes of 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate Synthase from Saccharomyces Cerevisiae Provide New Insights Into the Catalytic Mechanism J.Mol.Biol., 337, 2004
|
|
1OFO
| Crystal Structure of the Tyrosine Regulated 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate Synthase from Saccharomyces Cerevisiae in Complex with 2-Phosphoglycolate | Descriptor: | 2-PHOSPHOGLYCOLIC ACID, PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE | Authors: | Koenig, V, Pfeil, A, Heinrich, G, Braus, G, Schneider, T.R. | Deposit date: | 2003-04-17 | Release date: | 2004-04-15 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.86 Å) | Cite: | Substrate and Metal Complexes of 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate Synthase from Saccharomyces Cerevisiae Provide New Insights Into the Catalytic Mechanism. J.Mol.Biol., 337, 2004
|
|
1OFB
| CRYSTAL STRUCTURE OF THE TYROSINE-REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE FROM SACCHAROMYCES CEREVISIAE IN COMPLEX WITH MANGANESE(II) | Descriptor: | GLYCEROL, MANGANESE (II) ION, PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE | Authors: | Koenig, V, Pfeil, A, Heinrich, G, Braus, G.H, Schneider, T.R. | Deposit date: | 2003-04-09 | Release date: | 2004-04-08 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.01 Å) | Cite: | Substrate and Metal Complexes of 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate Synthase from Saccharomyces Cerevisiae Provide New Insights Into the Catalytic Mechanism J.Mol.Biol., 337, 2004
|
|
1OK0
| Crystal Structure of Tendamistat | Descriptor: | ALPHA-AMYLASE INHIBITOR HOE-467A, CHLORIDE ION, GLYCEROL | Authors: | Koenig, V, Vertesy, L, Schneider, T.R. | Deposit date: | 2003-07-16 | Release date: | 2004-01-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (0.93 Å) | Cite: | Crystal Structure of the Alpha-Amylase Inhibitor Tendamistat at 0.93 A Acta Crystallogr.,Sect.D, 59, 2003
|
|
1NTT
| 5'(dCPCPUPCPCPUPUP)3':(rAGGAGGAAA)5', where P=propynyl | Descriptor: | 5'-D(*CP*(5PC)P*(PDU)P*(5PC)P*(5PC)P*(PDU)P*(PDU))-3', 5'-R(*AP*AP*AP*GP*GP*AP*GP*GP*A)-3' | Authors: | Znosko, B.M, Barnes III, T.W, Krugh, T.R, Turner, D.H. | Deposit date: | 2003-01-30 | Release date: | 2003-06-10 | Last modified: | 2024-05-01 | Method: | SOLUTION NMR | Cite: | NMR Studies of DNA Single Strands and DNA:RNA Hybrids With and Without 1-Propynylation at C5 of Oligopyrimidines J.Am.Chem.Soc., 125, 2003
|
|
1OFR
| CRYSTAL STRUCTURE OF THE TYROSINE-REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE FROM SACCHAROMYCES CEREVISIAE COMPLEXED WITH PHENYLALANINE AND MANGANESE | Descriptor: | MANGANESE (II) ION, PHENYLALANINE, PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE | Authors: | Koenig, V, Pfeil, A, Heinrich, G, Braus, G, Schneider, T.R. | Deposit date: | 2003-04-18 | Release date: | 2004-04-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Substrate and Metal Complexes of 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate Synthase from Saccharomyces Cerevisiae Provide New Insights Into the Catalytic Mechanism. J.Mol.Biol., 337, 2004
|
|
1OFP
| CRYSTAL STRUCTURE OF THE TYROSINE-REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE FROM SACCHAROMYCES CEREVISIAE | Descriptor: | PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE | Authors: | Koenig, V, Pfeil, A, Heinrich, G, Braus, G.H, Schneider, T.R. | Deposit date: | 2003-04-17 | Release date: | 2004-04-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Substrate and Metal Complexes of 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate Synthase from Saccharomyces Cerevisiae Provide New Insights Into the Catalytic Mechanism J.Mol.Biol., 337, 2004
|
|
1OFQ
| CRYSTAL STRUCTURE OF THE TYROSINE-REGULATED 3-DEOXY-D-ARABINO-HEPTULOSONATE-7-PHOSPHATE SYNTHASE FROM SACCHAROMYCES CEREVISIAE IN COMPLEX WITH MANGANESE(II) | Descriptor: | MANGANESE (II) ION, PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE | Authors: | Koenig, V, Pfeil, A, Heinrich, G, Braus, G.H, Schneider, T.R. | Deposit date: | 2003-04-17 | Release date: | 2004-04-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Substrate and Metal Complexes of 3-Deoxy-D-Arabino-Heptulosonate-7-Phosphate Synthase from Saccharomyces Cerevisiae Provide New Insights Into the Catalytic Mechanism J.Mol.Biol., 337, 2004
|
|
1PGY
| Solution structure of the UBA domain in Saccharomyces cerevisiae protein, Swa2p | Descriptor: | Swa2p | Authors: | Chim, N, Gall, W.E, Xiao, J, Harris, M.P, Graham, T.R, Krezel, A.M. | Deposit date: | 2003-05-28 | Release date: | 2004-03-23 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | Solution structure of the ubiquitin-binding domain in Swa2p from Saccharomyces cerevisiae. PROTEINS: STRUCT.,FUNCT.,GENET., 54, 2004
|
|
1NTQ
| 5'(dCCUCCUU)3':3'(rAGGAGGAAA)5' | Descriptor: | 5'-D(*CP*CP*UP*CP*CP*UP*U)-3', 5'-R(*AP*AP*AP*GP*GP*AP*GP*GP*A)-3' | Authors: | Znosko, B.M, Barnes III, T.W, Krugh, T.R, Turner, D.H. | Deposit date: | 2003-01-30 | Release date: | 2003-06-10 | Last modified: | 2022-02-23 | Method: | SOLUTION NMR | Cite: | NMR Studies of DNA Single Strands and DNA:RNA Hybrids With and Without 1-Propynylation at C5 of Oligopyrimidines J.Am.Chem.Soc., 125, 2003
|
|