7S9G
Room-temperature Human Hsp90a-NTD bound to BIIB021
Summary for 7S9G
| Entry DOI | 10.2210/pdb7s9g/pdb |
| Descriptor | Heat shock protein HSP 90-alpha, 6-chloro-9-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]-9H-purin-2-amine, MAGNESIUM ION, ... (4 entities in total) |
| Functional Keywords | chaperone protein, signal transduction, heat shock, chaperone, hydrolase |
| Biological source | Homo sapiens (Human) |
| Total number of polymer chains | 1 |
| Total formula weight | 27082.99 |
| Authors | Stachowski, T.R.,Vanarotti, M.,Fischer, M. (deposition date: 2021-09-21, release date: 2022-08-03, Last modification date: 2023-10-18) |
| Primary citation | Stachowski, T.R.,Vanarotti, M.,Seetharaman, J.,Lopez, K.,Fischer, M. Water Networks Repopulate Protein-Ligand Interfaces with Temperature. Angew.Chem.Int.Ed.Engl., 61:e202112919-e202112919, 2022 Cited by PubMed: 35648650DOI: 10.1002/anie.202112919 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (1.79 Å) |
Structure validation
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